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Yan Zhou, Na Li, Qi Zheng, Wei Han, Luqian Zhou, Hui Zhao, Xunchao Liu, Wuping Bao, Yilin Pan, Yingying Zhang, Chengjian Lv, Huifang Cao, Dang Li, Changsheng Ge, Hui Zhu, Shilong Zhu, Huahao Shen, and Min Zhang have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"This study protocol was approved by the Institutional Review Board of Shanghai General Hospital (Ethics No. YL2022-005) and registered on chictr.org.cn (No. ChiCTR2400094311). Ethical approval numbers for all participating institutions are provided in the Supplementary Material. Written informed consent was obtained from all participants.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}