{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:11:59Z","timestamp":1790190719842,"version":"4.1.0"},"reference-count":40,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T00:00:00Z","timestamp":1751500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2025,9]]},"DOI":"10.1007\/s12325-025-03282-9","type":"journal-article","created":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T04:39:01Z","timestamp":1751517541000},"page":"4403-4417","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Relationships Among Glaucoma, Cardiovascular Diseases, and Mortality"],"prefix":"10.1007","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5462-1713","authenticated-orcid":false,"given":"Luciano","family":"Quaranta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0163-1034","authenticated-orcid":false,"given":"Alessia A.","family":"Galbussera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7345-0887","authenticated-orcid":false,"given":"Mauro","family":"Tettamanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5927-811X","authenticated-orcid":false,"given":"Alessio","family":"Novella","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4777-1350","authenticated-orcid":false,"given":"Luca","family":"Pasina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-6006-0376","authenticated-orcid":false,"given":"Ida","family":"Fortino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6906-2424","authenticated-orcid":false,"given":"Olivia","family":"Leoni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2504-0004","authenticated-orcid":false,"given":"Francesco","family":"Oddone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5260-0126","authenticated-orcid":false,"given":"Sara","family":"Giammaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4822-4291","authenticated-orcid":false,"given":"Miko\u0142aj","family":"Ku\u017cniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9553-3202","authenticated-orcid":false,"given":"Robert N.","family":"Weinreb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7813-0572","authenticated-orcid":false,"given":"Alessandro","family":"Nobili","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,7,3]]},"reference":[{"issue":"10108","key":"3282_CR1","doi-asserted-by":"publisher","first-page":"2183","DOI":"10.1016\/S0140-6736(17)31469-1","volume":"390","author":"JB Jonas","year":"2017","unstructured":"Jonas JB, Aung T, Bourne RR, Bron AM, Ritch R, Panda-Jonas S. Glaucoma. Lancet. 2017;390(10108):2183\u201393. https:\/\/doi.org\/10.1016\/S0140-6736(17)31469-1.","journal-title":"Lancet"},{"issue":"11","key":"3282_CR2","doi-asserted-by":"publisher","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","volume":"121","author":"YC Tham","year":"2014","unstructured":"Tham YC, Li X, Wong TY, Quigley HA, Aung T, Cheng CY. Global prevalence of glaucoma and projections of glaucoma burden through 2040. Ophthalmology. 2014;121(11):2081\u201390. https:\/\/doi.org\/10.1016\/j.ophtha.2014.05.013.","journal-title":"Ophthalmology"},{"issue":"18","key":"3282_CR3","doi-asserted-by":"publisher","first-page":"1901","DOI":"10.1001\/jama.2014.3192","volume":"311","author":"RN Weinreb","year":"2014","unstructured":"Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014;311(18):1901. https:\/\/doi.org\/10.1001\/jama.2014.3192.","journal-title":"JAMA"},{"issue":"3","key":"3282_CR4","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1093\/ajh\/hpad111","volume":"37","author":"J Van Eijgen","year":"2024","unstructured":"Van Eijgen J, Melgarejo JD, Van Laeken J, et al. The relevance of arterial blood pressure in the management of glaucoma progression: a systematic review. Am J Hypertens. 2024;37(3):179\u201398. https:\/\/doi.org\/10.1093\/ajh\/hpad111.","journal-title":"Am J Hypertens"},{"issue":"1","key":"3282_CR5","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.survophthal.2012.05.003","volume":"58","author":"L Quaranta","year":"2013","unstructured":"Quaranta L, Katsanos A, Russo A, Riva I. 24-hour intraocular pressure and ocular perfusion pressure in glaucoma. Surv Ophthalmol. 2013;58(1):26\u201341. https:\/\/doi.org\/10.1016\/j.survophthal.2012.05.003.","journal-title":"Surv Ophthalmol"},{"key":"3282_CR6","doi-asserted-by":"publisher","first-page":"S3","DOI":"10.1016\/0039-6257(94)90041-8","volume":"38","author":"J Flammer","year":"1994","unstructured":"Flammer J. The vascular concept of glaucoma. Surv Ophthalmol. 1994;38:S3\u20136. https:\/\/doi.org\/10.1016\/0039-6257(94)90041-8.","journal-title":"Surv Ophthalmol"},{"issue":"1","key":"3282_CR7","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1186\/1878-5085-4-14","volume":"4","author":"J Flammer","year":"2013","unstructured":"Flammer J, Konieczka K, Flammer AJ. The primary vascular dysregulation syndrome: implications for eye diseases. EPMA Journal. 2013;4(1):14. https:\/\/doi.org\/10.1186\/1878-5085-4-14.","journal-title":"EPMA Journal"},{"issue":"1","key":"3282_CR8","doi-asserted-by":"publisher","first-page":"2712","DOI":"10.1038\/s41598-023-29613-w","volume":"13","author":"JA Choi","year":"2023","unstructured":"Choi JA, Lee SN, Jung SH, Won HH, Yun JS. Association of glaucoma and lifestyle with incident cardiovascular disease: a longitudinal prospective study from UK Biobank. Sci Rep. 2023;13(1):2712. https:\/\/doi.org\/10.1038\/s41598-023-29613-w.","journal-title":"Sci Rep"},{"key":"3282_CR9","doi-asserted-by":"publisher","first-page":"1034976","DOI":"10.3389\/fneur.2022.1034976","volume":"13","author":"M Wang","year":"2022","unstructured":"Wang M, Chen N, Sun BC, et al. Association between glaucoma and risk of stroke: a systematic review and meta-analysis. Front Neurol. 2022;13:1034976. https:\/\/doi.org\/10.3389\/fneur.2022.1034976.","journal-title":"Front Neurol"},{"issue":"7","key":"3282_CR10","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1016\/j.ophtha.2006.02.062","volume":"113","author":"AJ Lee","year":"2006","unstructured":"Lee AJ, Wang JJ, Kifley A, Mitchell P. Open-angle glaucoma and cardiovascular mortality: the Blue Mountains Eye Study. Ophthalmology. 2006;113(7):1069\u201376. https:\/\/doi.org\/10.1016\/j.ophtha.2006.02.062.","journal-title":"Ophthalmology"},{"issue":"2","key":"3282_CR11","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1001\/archophthalmol.2008.571","volume":"127","author":"M Akbari","year":"2009","unstructured":"Akbari M. The association of primary open-angle glaucoma with mortality: a meta-analysis of observational studies. Arch Ophthalmol. 2009;127(2):204. https:\/\/doi.org\/10.1001\/archophthalmol.2008.571.","journal-title":"Arch Ophthalmol"},{"issue":"3","key":"3282_CR12","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1001\/archopht.1995.01100030089026","volume":"113","author":"R Klein","year":"1995","unstructured":"Klein R. Age-related eye disease and survival: the Beaver Dam eye study. Arch Ophthalmol. 1995;113(3):333. https:\/\/doi.org\/10.1001\/archopht.1995.01100030089026.","journal-title":"Arch Ophthalmol"},{"key":"3282_CR13","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/bs.pbr.2015.04.010","volume":"221","author":"C Nucci","year":"2015","unstructured":"Nucci C, Martucci A, Cesareo M, et al. Links among glaucoma, neurodegenerative, and vascular diseases of the central nervous system. Prog Brain Res. 2015;221:49\u201365. https:\/\/doi.org\/10.1016\/bs.pbr.2015.04.010.","journal-title":"Prog Brain Res"},{"issue":"9","key":"3282_CR14","doi-asserted-by":"publisher","first-page":"875","DOI":"10.1093\/aje\/153.9.875","volume":"153","author":"FB Hu","year":"2001","unstructured":"Hu FB. Prospective study of cataract extraction and risk of coronary heart disease in women. Am J Epidemiol. 2001;153(9):875\u201381. https:\/\/doi.org\/10.1093\/aje\/153.9.875.","journal-title":"Am J Epidemiol"},{"issue":"11","key":"3282_CR15","doi-asserted-by":"publisher","first-page":"1487","DOI":"10.1001\/archopht.117.11.1487","volume":"117","author":"R Klein","year":"1999","unstructured":"Klein R, Klein BE, Moss SE, Cruickshanks KJ. Association of ocular disease and mortality in a diabetic population. Arch Ophthalmol. 1999;117(11):1487\u201395. https:\/\/doi.org\/10.1001\/archopht.117.11.1487.","journal-title":"Arch Ophthalmol"},{"issue":"23","key":"3282_CR16","doi-asserted-by":"publisher","first-page":"1438","DOI":"10.1056\/NEJM198512053132303","volume":"313","author":"MJ Podgor","year":"1985","unstructured":"Podgor MJ, Cassel GH, Kannel WB. Lens changes and survival in a population-based study. N Engl J Med. 1985;313(23):1438\u201344. https:\/\/doi.org\/10.1056\/NEJM198512053132303.","journal-title":"N Engl J Med"},{"issue":"3","key":"3282_CR17","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1001\/archopht.118.3.393","volume":"118","author":"SK West","year":"2000","unstructured":"West SK. Mixed lens opacities and subsequent mortality. Arch Ophthalmol. 2000;118(3):393. https:\/\/doi.org\/10.1001\/archopht.118.3.393.","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"3282_CR18","doi-asserted-by":"publisher","first-page":"440","DOI":"10.1016\/S0002-9394(99)00187-7","volume":"128","author":"R Hiller","year":"1999","unstructured":"Hiller R, Podgor MJ, Sperduto RD, Wilson PWF, Chew EY, D\u2019Agostino RB. High intraocular pressure and survival: the Framingham studies. Am J Ophthalmol. 1999;128(4):440\u20135. https:\/\/doi.org\/10.1016\/S0002-9394(99)00187-7.","journal-title":"Am J Ophthalmol"},{"issue":"4","key":"3282_CR19","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1034\/j.1600-0420.1999.770407.x","volume":"77","author":"K Egge","year":"1999","unstructured":"Egge K, Zahl PH. Survival of glaucoma patients: survival of glaucoma patients. Acta Ophthalmol Scand. 1999;77(4):397\u2013401. https:\/\/doi.org\/10.1034\/j.1600-0420.1999.770407.x.","journal-title":"Acta Ophthalmol Scand"},{"issue":"12","key":"3282_CR20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0188377","volume":"12","author":"R Gini","year":"2017","unstructured":"Gini R, Schuemie MJ, Pasqua A, et al. Monitoring compliance with standards of care for chronic diseases using healthcare administrative databases in Italy: strengths and limitations. PLoS ONE. 2017;12(12):e0188377. https:\/\/doi.org\/10.1371\/journal.pone.0188377.","journal-title":"PLoS ONE"},{"issue":"7","key":"3282_CR21","doi-asserted-by":"publisher","first-page":"967","DOI":"10.1016\/j.ophtha.2019.03.001","volume":"126","author":"J Kwon","year":"2019","unstructured":"Kwon J, Jo YH, Jeong D, Shon K, Kook MS. Baseline systolic versus diastolic blood pressure dip and subsequent visual field progression in normal-tension glaucoma. Ophthalmology. 2019;126(7):967\u201379. https:\/\/doi.org\/10.1016\/j.ophtha.2019.03.001.","journal-title":"Ophthalmology"},{"issue":"17","key":"3282_CR22","doi-asserted-by":"publisher","first-page":"13211","DOI":"10.3390\/ijms241713211","volume":"24","author":"X Wang","year":"2023","unstructured":"Wang X, Wang M, Liu H, et al. The association between vascular abnormalities and glaucoma-what comes first? Int J Mol Sci. 2023;24(17):13211. https:\/\/doi.org\/10.3390\/ijms241713211.","journal-title":"Int J Mol Sci"},{"issue":"5","key":"3282_CR23","doi-asserted-by":"publisher","first-page":"944","DOI":"10.1161\/HYPERTENSIONAHA.118.11507","volume":"73","author":"M Leeman","year":"2019","unstructured":"Leeman M, Kestelyn P. Glaucoma and blood pressure. Hypertension. 2019;73(5):944\u201350. https:\/\/doi.org\/10.1161\/HYPERTENSIONAHA.118.11507.","journal-title":"Hypertension"},{"issue":"10","key":"3282_CR24","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1007\/s11892-021-01404-5","volume":"21","author":"Y Li","year":"2021","unstructured":"Li Y, Mitchell W, Elze T, Zebardast N. Association between diabetes, diabetic retinopathy, and glaucoma. Curr Diab Rep. 2021;21(10):38. https:\/\/doi.org\/10.1007\/s11892-021-01404-5.","journal-title":"Curr Diab Rep"},{"issue":"9288","key":"3282_CR25","doi-asserted-by":"publisher","first-page":"1134","DOI":"10.1016\/S0140-6736(01)06253-5","volume":"358","author":"TY Wong","year":"2001","unstructured":"Wong TY, Klein R, Couper DJ, et al. Retinal microvascular abnormalities and incident stroke: the Atherosclerosis Risk in Communities Study. Lancet. 2001;358(9288):1134\u201340. https:\/\/doi.org\/10.1016\/S0140-6736(01)06253-5.","journal-title":"Lancet"},{"issue":"4","key":"3282_CR26","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1055\/a-2275-2323","volume":"241","author":"K Konieczka","year":"2024","unstructured":"Konieczka K. Glaucoma patient with suspected Flammer syndrome: diagnostic procedures and therapeutic implications. Klin Monbl Augenheilkd. 2024;241(4):355\u201360. https:\/\/doi.org\/10.1055\/a-2275-2323.","journal-title":"Klin Monbl Augenheilkd"},{"issue":"4","key":"3282_CR27","doi-asserted-by":"publisher","first-page":"712","DOI":"10.1016\/s0161-6420(97)30247-4","volume":"104","author":"P Mitchell","year":"1997","unstructured":"Mitchell P, Smith W, Chey T, Healey PR. Open-angle glaucoma and diabetes: the Blue Mountains eye study, Australia. Ophthalmology. 1997;104(4):712\u20138. https:\/\/doi.org\/10.1016\/s0161-6420(97)30247-4.","journal-title":"Ophthalmology"},{"issue":"7","key":"3282_CR28","doi-asserted-by":"publisher","first-page":"1173","DOI":"10.1016\/s0161-6420(94)31191-2","volume":"101","author":"BE Klein","year":"1994","unstructured":"Klein BE, Klein R, Jensen SC. Open-angle glaucoma and older-onset diabetes. The Beaver Dam Eye Study. Ophthalmology. 1994;101(7):1173\u20137. https:\/\/doi.org\/10.1016\/s0161-6420(94)31191-2.","journal-title":"Ophthalmology"},{"issue":"11","key":"3282_CR29","doi-asserted-by":"publisher","first-page":"1218","DOI":"10.1136\/bjo.84.11.1218","volume":"84","author":"JD Ellis","year":"2000","unstructured":"Ellis JD, Evans JM, Ruta DA, et al. Glaucoma incidence in an unselected cohort of diabetic patients: is diabetes mellitus a risk factor for glaucoma? DARTS\/MEMO collaboration. Diabetes Audit and Research in Tayside Study. Medicines Monitoring Unit. Br J Ophthalmol. 2000;84(11):1218\u201324. https:\/\/doi.org\/10.1136\/bjo.84.11.1218.","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"3282_CR30","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1016\/s0161-6420(95)31055-x","volume":"102","author":"JM Tielsch","year":"1995","unstructured":"Tielsch JM, Katz J, Quigley HA, Javitt JC, Sommer A. Diabetes, intraocular pressure, and primary open-angle glaucoma in the Baltimore Eye Survey. Ophthalmology. 1995;102(1):48\u201353. https:\/\/doi.org\/10.1016\/s0161-6420(95)31055-x.","journal-title":"Ophthalmology"},{"issue":"1","key":"3282_CR31","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1080\/00015385.2018.1549004","volume":"75","author":"KC Yilmaz","year":"2020","unstructured":"Yilmaz KC, Sur Gungor S, Ciftci O, Akman A, Muderrisoglu H. Relationship between primary open angle glaucoma and blood pressure. Acta Cardiol. 2020;75(1):54\u20138. https:\/\/doi.org\/10.1080\/00015385.2018.1549004.","journal-title":"Acta Cardiol"},{"issue":"7","key":"3282_CR32","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1038\/s41433-018-0057-8","volume":"32","author":"P Raman","year":"2018","unstructured":"Raman P, Suliman NB, Zahari M, Kook M, Ramli N. Low nocturnal diastolic ocular perfusion pressure as a risk factor for NTG progression: a 5-year prospective study. Eye (Lond). 2018;32(7):1183\u20139. https:\/\/doi.org\/10.1038\/s41433-018-0057-8.","journal-title":"Eye (Lond)"},{"issue":"9","key":"3282_CR33","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1093\/ajh\/hpv016","volume":"28","author":"A Bowe","year":"2015","unstructured":"Bowe A, Gr\u00fcnig M, Schubert J, et al. Circadian variation in arterial blood pressure and glaucomatous optic neuropathy\u2014a systematic review and meta-analysis. Am J Hypertens. 2015;28(9):1077\u201382. https:\/\/doi.org\/10.1093\/ajh\/hpv016.","journal-title":"Am J Hypertens"},{"issue":"7","key":"3282_CR34","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1097\/IJG.0000000000000981","volume":"27","author":"CG De Moraes","year":"2018","unstructured":"De Moraes CG, Cioffi GA, Weinreb RN, Liebmann JM. New recommendations for the treatment of systemic hypertension and their potential implications for glaucoma management. J Glaucoma. 2018;27(7):567\u201371. https:\/\/doi.org\/10.1097\/IJG.0000000000000981.","journal-title":"J Glaucoma"},{"issue":"11","key":"3282_CR35","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1007\/s11886-017-0927-x","volume":"19","author":"RM Levine","year":"2017","unstructured":"Levine RM, Yang A, Brahma V, Martone JF. Management of blood pressure in patients with glaucoma. Curr Cardiol Rep. 2017;19(11):109. https:\/\/doi.org\/10.1007\/s11886-017-0927-x.","journal-title":"Curr Cardiol Rep"},{"issue":"7","key":"3282_CR36","doi-asserted-by":"publisher","first-page":"739","DOI":"10.1016\/j.jfo.2019.03.007","volume":"42","author":"R Karadag","year":"2019","unstructured":"Karadag R, Koyun E, Ozsoy I, Caliskan M. Evaluation of the 24-hour intraocular pressure and systemic blood pressure at the same time. J Fr Ophtalmol. 2019;42(7):739\u201345. https:\/\/doi.org\/10.1016\/j.jfo.2019.03.007.","journal-title":"J Fr Ophtalmol"},{"issue":"3","key":"3282_CR37","doi-asserted-by":"publisher","first-page":"338","DOI":"10.1136\/bjophthalmol-2017-310415","volume":"102","author":"TH Rim","year":"2018","unstructured":"Rim TH, Lee SY, Bae HW, Kim SS, Kim CY. Increased stroke risk among patients with open-angle glaucoma: a 10-year follow-up cohort study. Br J Ophthalmol. 2018;102(3):338\u201343. https:\/\/doi.org\/10.1136\/bjophthalmol-2017-310415.","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"3282_CR38","doi-asserted-by":"publisher","first-page":"1952","DOI":"10.1038\/s41598-025-85505-1","volume":"15","author":"KI Jung","year":"2025","unstructured":"Jung KI, Kim YC, Shin HJ, Park CK. Nationwide cohort study of primary open angle glaucoma risk and cardiovascular factors among in Korean glaucoma suspects. Sci Rep. 2025;15(1):1952. https:\/\/doi.org\/10.1038\/s41598-025-85505-1.","journal-title":"Sci Rep"},{"issue":"3","key":"3282_CR39","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1001\/archophthalmol.2007.77","volume":"126","author":"SY Wu","year":"2008","unstructured":"Wu SY. Open-angle glaucoma and mortality: the Barbados eye studies. Arch Ophthalmol. 2008;126(3):365. https:\/\/doi.org\/10.1001\/archophthalmol.2007.77.","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"3282_CR40","doi-asserted-by":"publisher","first-page":"e336","DOI":"10.1111\/aos.12354","volume":"92","author":"A Huck","year":"2014","unstructured":"Huck A, Harris A, Siesky B, et al. Vascular considerations in glaucoma patients of African and European descent. Acta Ophthalmol. 2014;92(5):e336-340. https:\/\/doi.org\/10.1111\/aos.12354.","journal-title":"Acta Ophthalmol"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03282-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-025-03282-9","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03282-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,18]],"date-time":"2026-04-18T07:28:54Z","timestamp":1776497334000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-025-03282-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,3]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9]]}},"alternative-id":["3282"],"URL":"https:\/\/doi.org\/10.1007\/s12325-025-03282-9","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,3]]},"assertion":[{"value":"14 February 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"5 June 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 July 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Luciano Quaranta received payment honoraria for educational events by Thea, Abbvie and Omikron. Robert N Weinreb received grants from NIH and Research to Prevent Blindness. Luciano Quaranta is an Editorial Board member of\n                      Advances in Therapy\n                      . Luciano Quaranta was not involved in the selection of peer reviewers for the manuscript or any of the subsequent editorial decisions. Alessia A. Galbussera, Mauro Tettamanti, Alessio Novella, Luca Pasina, Ida Fortino, Olivia Leoni, Francesco Oddone, Sara Giammaria, Miko\u0142aj Ku\u017cniak, and Alessandro Nobili have nothing to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"According to the Italian law, studies using anonymous data from administrative databases that do not involve direct access to individual patient data need no approval from or notification by an ethics committee\/institutional review board, and informed patient consent is not required. All data were managed according to Italian law on privacy.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}