{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T11:07:40Z","timestamp":1782990460227,"version":"3.54.5"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"11","license":[{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T00:00:00Z","timestamp":1758240000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1007\/s12325-025-03369-3","type":"journal-article","created":{"date-parts":[[2025,9,19]],"date-time":"2025-09-19T03:53:56Z","timestamp":1758254036000},"page":"5427-5450","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Intraoperative Ventilatory Strategies in Patients Undergoing Video-Assisted Thoracic Surgery: A Narrative Review"],"prefix":"10.1007","volume":"42","author":[{"given":"Silvia","family":"Coppola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Pastene","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Fratti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mert","family":"Sent\u00fcrk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebru","family":"Emre Demirel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Leone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide Alberto","family":"Chiumello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,9,19]]},"reference":[{"issue":"6","key":"3369_CR1","doi-asserted-by":"publisher","first-page":"S2118","DOI":"10.1016\/j.athoracsur.2010.03.017","volume":"89","author":"K Kim","year":"2010","unstructured":"Kim K, Kim HK, Park JS, et al. Video-assisted thoracic surgery lobectomy: single institutional experience with 704 cases. Ann Thorac Surg. 2010;89(6):S2118\u201322. https:\/\/doi.org\/10.1016\/j.athoracsur.2010.03.017.","journal-title":"Ann Thorac Surg"},{"issue":"15","key":"3369_CR2","doi-asserted-by":"publisher","first-page":"2553","DOI":"10.1200\/JCO.2008.18.2733","volume":"27","author":"TD Yan","year":"2009","unstructured":"Yan TD, Black D, Bannon PG, McCaughan BC. Systematic review and meta-analysis of randomized and nonrandomized trials on safety and efficacy of video-assisted thoracic surgery lobectomy for early-stage non\u2013small-cell lung cancer. JCO. 2009;27(15):2553\u201362. https:\/\/doi.org\/10.1200\/JCO.2008.18.2733.","journal-title":"JCO"},{"issue":"2","key":"3369_CR3","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1213\/ane.0000000000000808","volume":"121","author":"J Lohser","year":"2015","unstructured":"Lohser J, Slinger P. Lung injury after one-lung ventilation: a review of the pathophysiologic mechanisms affecting the ventilated and the collapsed lung. Anesth Analg. 2015;121(2):302\u201318. https:\/\/doi.org\/10.1213\/ane.0000000000000808.","journal-title":"Anesth Analg"},{"issue":"10","key":"3369_CR4","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1097\/EJA.0000000000000804","volume":"35","author":"E Marret","year":"2018","unstructured":"Marret E, Cinotti R, Berard L, et al. Protective ventilation during anaesthesia reduces major postoperative complications after lung cancer surgery: a double-blind randomised controlled trial. Eur J Anaesthesiol. 2018;35(10):727\u201335. https:\/\/doi.org\/10.1097\/EJA.0000000000000804.","journal-title":"Eur J Anaesthesiol"},{"issue":"4","key":"3369_CR5","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1016\/j.jclinepi.2010.07.015","volume":"64","author":"H Balshem","year":"2011","unstructured":"Balshem H, Helfand M, Sch\u00fcnemann HJ, et al. Grade guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64(4):401\u20136. https:\/\/doi.org\/10.1016\/j.jclinepi.2010.07.015.","journal-title":"J Clin Epidemiol"},{"issue":"1","key":"3369_CR6","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1097\/ACO.0000000000000945","volume":"34","author":"K Kaufmann","year":"2021","unstructured":"Kaufmann K, Heinrich S. Minimizing postoperative pulmonary complications in thoracic surgery patients. Curr Opin Anaesthesiol. 2021;34(1):13\u20139. https:\/\/doi.org\/10.1097\/ACO.0000000000000945.","journal-title":"Curr Opin Anaesthesiol"},{"issue":"1","key":"3369_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1097\/ACO.0000000000000669","volume":"32","author":"A Pedoto","year":"2019","unstructured":"Pedoto A, Perrino AC. Delayed recovery following thoracic surgery: persistent issues and potential interventions. Curr Opin Anaesthesiol. 2019;32(1):3\u20139. https:\/\/doi.org\/10.1097\/ACO.0000000000000669.","journal-title":"Curr Opin Anaesthesiol"},{"issue":"15","key":"3369_CR8","doi-asserted-by":"publisher","first-page":"356","DOI":"10.21037\/atm.2019.03.67","volume":"7","author":"D Lederman","year":"2019","unstructured":"Lederman D, Easwar J, Feldman J, Shapiro V. Anesthetic considerations for lung resection: preoperative assessment, intraoperative challenges and postoperative analgesia. Ann Transl Med. 2019;7(15):356\u2013356. https:\/\/doi.org\/10.21037\/atm.2019.03.67.","journal-title":"Ann Transl Med"},{"issue":"18","key":"3369_CR9","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1056\/NEJM200005043421801","volume":"342","author":"ARDS Network","year":"2000","unstructured":"Network ARDS. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342(18):1301\u20138. https:\/\/doi.org\/10.1056\/NEJM200005043421801.","journal-title":"N Engl J Med"},{"issue":"3","key":"3369_CR10","doi-asserted-by":"publisher","first-page":"530","DOI":"10.1378\/chest.09-2293","volume":"139","author":"M Yang","year":"2011","unstructured":"Yang M, Ahn HJ, Kim K, et al. Does a protective ventilation strategy reduce the risk of pulmonary complications after lung cancer surgery? Chest. 2011;139(3):530\u20137. https:\/\/doi.org\/10.1378\/chest.09-2293.","journal-title":"Chest"},{"issue":"1","key":"3369_CR11","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1213\/ANE.0000000000002151","volume":"125","author":"D Amar","year":"2017","unstructured":"Amar D, Zhang H, Pedoto A, Desiderio DP, Shi W, Tan KS. Protective lung ventilation and morbidity after pulmonary resection: a propensity score-matched analysis. Anesth Analg. 2017;125(1):190\u20139. https:\/\/doi.org\/10.1213\/ANE.0000000000002151.","journal-title":"Anesth Analg"},{"issue":"5","key":"3369_CR12","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1007\/s00464-018-6415-6","volume":"33","author":"HJ Kim","year":"2019","unstructured":"Kim HJ, Seo JH, Park KU, Kim YT, Park IK, Bahk JH. Effect of combining a recruitment maneuver with protective ventilation on inflammatory responses in video-assisted thoracoscopic lobectomy: a randomized controlled trial. Surg Endosc. 2019;33(5):1403\u201311. https:\/\/doi.org\/10.1007\/s00464-018-6415-6.","journal-title":"Surg Endosc"},{"issue":"5","key":"3369_CR13","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1177\/0310057X1204000505","volume":"40","author":"HJ Ahn","year":"2012","unstructured":"Ahn HJ, Kim JA, Yang M, Shim WS, Park KJ, Lee JJ. Comparison between conventional and protective one-lung ventilation for ventilator-assisted thoracic surgery. Anaesth Intensive Care. 2012;40(5):780\u20138. https:\/\/doi.org\/10.1177\/0310057X1204000505.","journal-title":"Anaesth Intensive Care"},{"issue":"5","key":"3369_CR14","doi-asserted-by":"publisher","first-page":"2760","DOI":"10.21037\/jtd.2018.04.90","volume":"10","author":"W Liu","year":"2018","unstructured":"Liu W, Huang Q, Lin D, Zhao L, Ma J. Effect of lung protective ventilation on coronary heart disease patients undergoing lung cancer resection. J Thorac Dis. 2018;10(5):2760\u201370. https:\/\/doi.org\/10.21037\/jtd.2018.04.90.","journal-title":"J Thorac Dis"},{"issue":"9","key":"3369_CR15","doi-asserted-by":"publisher","first-page":"466","DOI":"10.1097\/EJA.0000000000000072","volume":"31","author":"H Qutub","year":"2014","unstructured":"Qutub H, El-Tahan MR, Mowafi HA, El Ghoneimy YF, Regal MA, Al Saflan AA. Effect of tidal volume on extravascular lung water content during one-lung ventilation for video-assisted thoracoscopic surgery: a randomised, controlled trial. Eur J Anaesthesiol. 2014;31(9):466\u201373. https:\/\/doi.org\/10.1097\/EJA.0000000000000072.","journal-title":"Eur J Anaesthesiol"},{"issue":"5","key":"3369_CR16","doi-asserted-by":"publisher","first-page":"1421","DOI":"10.3349\/ymj.2015.56.5.1421","volume":"56","author":"YS Choi","year":"2015","unstructured":"Choi YS, Bae MK, Kim SH, Park JE, Kim SY, Oh YJ. Effects of alveolar recruitment and positive end-expiratory pressure on oxygenation during one-lung ventilation in the supine position. Yonsei Med J. 2015;56(5):1421\u20137. https:\/\/doi.org\/10.3349\/ymj.2015.56.5.1421.","journal-title":"Yonsei Med J"},{"issue":"12","key":"3369_CR17","doi-asserted-by":"publisher","first-page":"2561","DOI":"10.1053\/j.jvca.2023.04.029","volume":"37","author":"F Piccioni","year":"2023","unstructured":"Piccioni F, Langiano N, Bignami E, et al. One-lung ventilation and postoperative pulmonary complications after major lung resection surgery. A multicenter randomized controlled trial. J Cardiothorac Vasc Anesth. 2023;37(12):2561\u201371. https:\/\/doi.org\/10.1053\/j.jvca.2023.04.029.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"4","key":"3369_CR18","doi-asserted-by":"publisher","first-page":"562","DOI":"10.1097\/ALN.0000000000003729","volume":"134","author":"DA Colquhoun","year":"2021","unstructured":"Colquhoun DA, Leis AM, Shanks AM, et al. A lower tidal volume regimen during one-lung ventilation for lung resection surgery is not associated with reduced postoperative pulmonary complications. Anesthesiology. 2021;134(4):562\u201376. https:\/\/doi.org\/10.1097\/ALN.0000000000003729.","journal-title":"Anesthesiology"},{"issue":"8","key":"3369_CR19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072675","volume":"8","author":"G Zick","year":"2013","unstructured":"Zick G, Elke G, Becher T, et al. Effect of PEEP and tidal volume on ventilation distribution and end-expiratory lung volume: a prospective experimental animal and pilot clinical study. PLoS ONE. 2013;8(8):e72675. https:\/\/doi.org\/10.1371\/journal.pone.0072675.","journal-title":"PLoS ONE"},{"key":"3369_CR20","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.938225","volume":"28","author":"W Yao","year":"2022","unstructured":"Yao W, Yang B, Wang W, et al. Effect of positive end-expiratory pressure (PEEP) titration in elderly patients undergoing lobectomy. Med Sci Monit. 2022;28:e938225. https:\/\/doi.org\/10.12659\/MSM.938225.","journal-title":"Med Sci Monit"},{"issue":"5","key":"3369_CR21","doi-asserted-by":"publisher","first-page":"565","DOI":"10.1016\/j.bjane.2021.04.001","volume":"71","author":"Y Zhang","year":"2021","unstructured":"Zhang Y, Zhang M, Wang X, Shang G, Dong Y. Individualized positive end-expiratory pressure in patients undergoing thoracoscopic lobectomy: a randomized controlled trial. Braz J Anesthesiol. 2021;71(5):565\u201371. https:\/\/doi.org\/10.1016\/j.bjane.2021.04.001.","journal-title":"Braz J Anesthesiol"},{"issue":"5","key":"3369_CR22","doi-asserted-by":"publisher","first-page":"1149","DOI":"10.1007\/s10877-020-00582-z","volume":"35","author":"S Spadaro","year":"2021","unstructured":"Spadaro S, Grasso S, Karbing DS, et al. Physiological effects of two driving pressure-based methods to set positive end-expiratory pressure during one lung ventilation. J Clin Monit Comput. 2021;35(5):1149\u201357. https:\/\/doi.org\/10.1007\/s10877-020-00582-z.","journal-title":"J Clin Monit Comput"},{"key":"3369_CR23","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58070940","author":"YS Kim","year":"2022","unstructured":"Kim YS, Seo KH, Jeon YS, et al. Effects of positive end-expiratory pressure on intraocular pressure during one-lung ventilation in the lateral decubitus position-a prospective randomized trial. Medicina (Kaunas). 2022. https:\/\/doi.org\/10.3390\/medicina58070940.","journal-title":"Medicina (Kaunas)"},{"issue":"3","key":"3369_CR24","doi-asserted-by":"publisher","first-page":"385","DOI":"10.1097\/ALN.0000000000002600","volume":"130","author":"M Park","year":"2019","unstructured":"Park M, Ahn HJ, Kim JA, et al. Driving pressure during thoracic surgery: a randomized clinical trial. Anesthesiology. 2019;130(3):385\u201393. https:\/\/doi.org\/10.1097\/ALN.0000000000002600.","journal-title":"Anesthesiology"},{"issue":"2","key":"3369_CR25","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.ccc.2006.12.005","volume":"23","author":"D Nichols","year":"2007","unstructured":"Nichols D, Haranath S. Pressure control ventilation. Crit Care Clin. 2007;23(2):183\u201399. https:\/\/doi.org\/10.1016\/j.ccc.2006.12.005.","journal-title":"Crit Care Clin"},{"issue":"3","key":"3369_CR26","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1016\/S0272-5231(05)70324-5","volume":"17","author":"NR MacIntyre","year":"1996","unstructured":"MacIntyre NR. New modes of mechanical ventilation. Clin Chest Med. 1996;17(3):411\u201321. https:\/\/doi.org\/10.1016\/S0272-5231(05)70324-5.","journal-title":"Clin Chest Med"},{"issue":"2","key":"3369_CR27","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1007\/BF00254777","volume":"11","author":"N Al-Saady","year":"1985","unstructured":"Al-Saady N, Bennett ED. Decelerating inspiratory flow waveform improves lung mechanics and gas exchange in patients on intermittent positive-pressure ventilation. Intensive Care Med. 1985;11(2):68\u201375. https:\/\/doi.org\/10.1007\/BF00254777.","journal-title":"Intensive Care Med"},{"issue":"4","key":"3369_CR28","doi-asserted-by":"publisher","first-page":"1382","DOI":"10.1378\/chest.122.4.1382","volume":"122","author":"M Prella","year":"2002","unstructured":"Prella M, Feihl F, Domenighetti G. Effects of short-term pressure-controlled ventilation on gas exchange, airway pressures, and gas distribution in patients with acute lung injury\/ARDS. Chest. 2002;122(4):1382\u20138. https:\/\/doi.org\/10.1378\/chest.122.4.1382.","journal-title":"Chest"},{"issue":"4","key":"3369_CR29","doi-asserted-by":"publisher","first-page":"258","DOI":"10.4097\/kjae.2014.67.4.258","volume":"67","author":"SY Song","year":"2014","unstructured":"Song SY, Jung JY, Cho MS, Kim JH, Ryu TH, Kim BI. Volume-controlled versus pressure-controlled ventilation-volume guaranteed mode during one-lung ventilation. Korean J Anesthesiol. 2014;67(4):258. https:\/\/doi.org\/10.4097\/kjae.2014.67.4.258.","journal-title":"Korean J Anesthesiol"},{"issue":"5","key":"3369_CR30","doi-asserted-by":"publisher","first-page":"1029","DOI":"10.1213\/01.ane.0000260313.63893.2f","volume":"104","author":"MC Unzueta","year":"2007","unstructured":"Unzueta MC, Casas JI, Moral MV. Pressure-controlled versus volume-controlled ventilation during one-lung ventilation for thoracic surgery. Anesth Analg. 2007;104(5):1029\u201333. https:\/\/doi.org\/10.1213\/01.ane.0000260313.63893.2f.","journal-title":"Anesth Analg"},{"issue":"6","key":"3369_CR31","first-page":"9955","volume":"8","author":"F Lin","year":"2015","unstructured":"Lin F, Pan L, Qian W, Ge W, Dai H, Liang Y. Comparison of three ventilatory modes during one-lung ventilation in elderly patients. Int J Clin Exp Med. 2015;8(6):9955\u201360.","journal-title":"Int J Clin Exp Med"},{"issue":"5","key":"3369_CR32","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.21037\/jtd.2017.04.36","volume":"9","author":"YQ Zhu","year":"2017","unstructured":"Zhu YQ, Fang F, Ling XM, Huang J, Cang J. Pressure-controlled versus volume-controlled ventilation during one-lung ventilation for video-assisted thoracoscopic lobectomy. J Thorac Dis. 2017;9(5):1303\u20139. https:\/\/doi.org\/10.21037\/jtd.2017.04.36.","journal-title":"J Thorac Dis"},{"issue":"3","key":"3369_CR33","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.21037\/jtd.2018.03.03","volume":"10","author":"J Tan","year":"2018","unstructured":"Tan J, Song Z, Bian Q, Li P, Gu L. Effects of volume-controlled ventilation vs. pressure-controlled ventilation on respiratory function and inflammatory factors in patients undergoing video-assisted thoracoscopic radical resection of pulmonary carcinoma. J Thorac Dis. 2018;10(3):1483\u20139. https:\/\/doi.org\/10.21037\/jtd.2018.03.03.","journal-title":"J Thorac Dis"},{"issue":"1","key":"3369_CR34","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1186\/1476-9255-8-32","volume":"8","author":"A Breunig","year":"2011","unstructured":"Breunig A, Gambazzi F, Beck-Schimmer B, et al. Cytokine & chemokine response in the lungs, pleural fluid and serum in thoracic surgery using one-lung ventilation. J Inflamm. 2011;8(1):32. https:\/\/doi.org\/10.1186\/1476-9255-8-32.","journal-title":"J Inflamm"},{"issue":"4","key":"3369_CR35","doi-asserted-by":"publisher","first-page":"511","DOI":"10.1111\/j.1440-1843.2009.01516.x","volume":"14","author":"C Wu","year":"2009","unstructured":"Wu C, Lin L, Yang J, Chan M, Hsueh C. Attenuation of lipopolysaccharide-induced acute lung injury by treatment with IL-10. Respirology. 2009;14(4):511\u201321. https:\/\/doi.org\/10.1111\/j.1440-1843.2009.01516.x.","journal-title":"Respirology"},{"issue":"1","key":"3369_CR36","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1186\/s13019-019-0910-2","volume":"14","author":"R Kremer","year":"2019","unstructured":"Kremer R, Aboud W, Haberfeld O, Armali M, Barak M. Differential lung ventilation for increased oxygenation during one lung ventilation for video assisted lung surgery. J Cardiothorac Surg. 2019;14(1):89. https:\/\/doi.org\/10.1186\/s13019-019-0910-2.","journal-title":"J Cardiothorac Surg"},{"issue":"8","key":"3369_CR37","doi-asserted-by":"publisher","first-page":"5057","DOI":"10.21037\/jtd.2018.07.79","volume":"10","author":"DK Lee","year":"2018","unstructured":"Lee DK, Kim H, Kim HK, Chung DI, Han KN, Choi YH. CO(2) during single incisional thoracoscopic bleb resection with two-lung ventilation. J Thorac Dis. 2018;10(8):5057\u201365. https:\/\/doi.org\/10.21037\/jtd.2018.07.79.","journal-title":"J Thorac Dis"},{"issue":"4","key":"3369_CR38","doi-asserted-by":"publisher","first-page":"568","DOI":"10.1007\/s00540-012-1348-z","volume":"26","author":"SH Kim","year":"2012","unstructured":"Kim SH, Jung KT, An TH. Effects of tidal volume and PEEP on arterial blood gases and pulmonary mechanics during one-lung ventilation. J Anesth. 2012;26(4):568\u201373. https:\/\/doi.org\/10.1007\/s00540-012-1348-z.","journal-title":"J Anesth"},{"issue":"6","key":"3369_CR39","doi-asserted-by":"publisher","first-page":"899","DOI":"10.1510\/icvts.2010.264911","volume":"12","author":"MR El-Tahan","year":"2011","unstructured":"El-Tahan MR, El Ghoneimy YF, Regal MA, El Emam H. Comparative study of the non-dependent continuous positive pressure ventilation and high-frequency positive-pressure ventilation during one-lung ventilation for video-assisted thoracoscopic surgery. Interact Cardiovasc Thorac Surg. 2011;12(6):899\u2013902. https:\/\/doi.org\/10.1510\/icvts.2010.264911.","journal-title":"Interact Cardiovasc Thorac Surg"},{"issue":"6","key":"3369_CR40","doi-asserted-by":"publisher","first-page":"898","DOI":"10.1016\/j.bja.2019.08.017","volume":"123","author":"CC Young","year":"2019","unstructured":"Young CC, Harris EM, Vacchiano C, et al. Lung-protective ventilation for the surgical patient: international expert panel-based consensus recommendations. Br J Anaesth. 2019;123(6):898\u2013913. https:\/\/doi.org\/10.1016\/j.bja.2019.08.017.","journal-title":"Br J Anaesth"},{"issue":"1","key":"3369_CR41","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1186\/s12871-020-01098-4","volume":"20","author":"C Uhlig","year":"2020","unstructured":"Uhlig C, Neto AS, Van Der Woude M, et al. Intraoperative mechanical ventilation practice in thoracic surgery patients and its association with postoperative pulmonary complications: results of a multicenter prospective observational study. BMC Anesthesiol. 2020;20(1):179. https:\/\/doi.org\/10.1186\/s12871-020-01098-4.","journal-title":"BMC Anesthesiol"},{"issue":"2","key":"3369_CR42","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1164\/rccm.200706-906OC","volume":"177","author":"Z Wang","year":"2008","unstructured":"Wang Z, Su F, Bruhn A, Yang X, Vincent JL. Acute hypercapnia improves indices of tissue oxygenation more than dobutamine in septic shock. Am J Respir Crit Care Med. 2008;177(2):178\u201383. https:\/\/doi.org\/10.1164\/rccm.200706-906OC.","journal-title":"Am J Respir Crit Care Med"},{"issue":"4","key":"3369_CR43","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1097\/00000542-200210000-00009","volume":"97","author":"O Ak\u00e7a","year":"2002","unstructured":"Ak\u00e7a O, Doufas AG, Morioka N, Iscoe S, Fisher J, Sessler DI. Hypercapnia improves tissue oxygenation. Anesthesiology. 2002;97(4):801\u20136. https:\/\/doi.org\/10.1097\/00000542-200210000-00009.","journal-title":"Anesthesiology"},{"issue":"9","key":"3369_CR44","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1097\/EJA.0000000000001873","volume":"40","author":"YE Joe","year":"2023","unstructured":"Joe YE, Lee CY, Kim N, Lee K, Kang SJ, Oh YJ. Effect of permissive hypercarbia on lung oxygenation during one-lung ventilation and postoperative pulmonary complications in patients undergoing thoracic surgery: a prospective randomised controlled trial. Eur J Anaesthesiol. 2023;40(9):691\u20138. https:\/\/doi.org\/10.1097\/EJA.0000000000001873.","journal-title":"Eur J Anaesthesiol"},{"issue":"5","key":"3369_CR45","doi-asserted-by":"publisher","first-page":"1215","DOI":"10.1378\/chest.109.5.1215","volume":"109","author":"DG Kiely","year":"1996","unstructured":"Kiely DG, Cargill RI, Lipworth BJ. Effects of hypercapnia on hemodynamic, inotropic, lusitropic, and electrophysiologic indices in humans. Chest. 1996;109(5):1215\u201321. https:\/\/doi.org\/10.1378\/chest.109.5.1215.","journal-title":"Chest"},{"issue":"1","key":"3369_CR46","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1378\/chest.126.1.281","volume":"126","author":"RJ Cerfolio","year":"2004","unstructured":"Cerfolio RJ, Bryant AS, Sheils TM, Bass CS, Bartolucci AA. Video-assisted thoracoscopic surgery using single-lumen endotracheal tube anesthesia. Chest. 2004;126(1):281\u20135. https:\/\/doi.org\/10.1378\/chest.126.1.281.","journal-title":"Chest"},{"issue":"5","key":"3369_CR47","doi-asserted-by":"publisher","first-page":"1183","DOI":"10.1183\/09031936.00056810","volume":"37","author":"H Kim","year":"2011","unstructured":"Kim H, Kim HK, Kang DY, Lee DK, Choi YH, Lim SH. A comparative study of two- versus one-lung ventilation for needlescopic bleb resection. Eur Respir J. 2011;37(5):1183\u20138. https:\/\/doi.org\/10.1183\/09031936.00056810.","journal-title":"Eur Respir J"},{"issue":"4","key":"3369_CR48","doi-asserted-by":"publisher","first-page":"972","DOI":"10.1053\/j.jvca.2014.06.029","volume":"29","author":"DK Lee","year":"2015","unstructured":"Lee DK, Kim HK, Lee K, Choi YH, Lim SH, Kim H. Optimal respiratory rate for low-tidal volume and two-lung ventilation in thoracoscopic bleb resection. J Cardiothorac Vasc Anesth. 2015;29(4):972\u20136. https:\/\/doi.org\/10.1053\/j.jvca.2014.06.029.","journal-title":"J Cardiothorac Vasc Anesth"},{"issue":"1","key":"3369_CR49","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1007\/s00464-019-06742-w","volume":"34","author":"R Souche","year":"2020","unstructured":"Souche R, Nayeri M, Chati R, et al. Thoracoscopy in prone position with two-lung ventilation compared to conventional thoracotomy during Ivor Lewis procedure: a multicenter case\u2013control study. Surg Endosc. 2020;34(1):142\u201352. https:\/\/doi.org\/10.1007\/s00464-019-06742-w.","journal-title":"Surg Endosc"},{"issue":"1","key":"3369_CR50","doi-asserted-by":"publisher","first-page":"6978","DOI":"10.1038\/s41598-021-86554-y","volume":"11","author":"Y Tanigawa","year":"2021","unstructured":"Tanigawa Y, Nakamura K, Yamashita T, Nakagawachi A, Sakaguchi Y. Changes in respiratory mechanics of artificial pneumothorax two-lung ventilation in video-assisted thoracoscopic esophagectomy in prone position. Sci Rep. 2021;11(1):6978. https:\/\/doi.org\/10.1038\/s41598-021-86554-y.","journal-title":"Sci Rep"},{"issue":"1","key":"3369_CR51","doi-asserted-by":"publisher","first-page":"117","DOI":"10.21037\/jtd.2017.01.27","volume":"9","author":"L Cai","year":"2017","unstructured":"Cai L, Li Y, Sun L, et al. Better perioperative outcomes in thoracoscopic-esophagectomy with two-lung ventilation in semi-prone position. J Thorac Dis. 2017;9(1):117\u201322. https:\/\/doi.org\/10.21037\/jtd.2017.01.27.","journal-title":"J Thorac Dis"},{"issue":"12","key":"3369_CR52","doi-asserted-by":"publisher","first-page":"5501","DOI":"10.1007\/s00464-019-07347-z","volume":"34","author":"S Nomura","year":"2020","unstructured":"Nomura S, Tsujimoto H, Ishibashi Y, et al. Efficacy of artificial pneumothorax under two-lung ventilation in video-assisted thoracoscopic surgery for esophageal cancer. Surg Endosc. 2020;34(12):5501\u20137. https:\/\/doi.org\/10.1007\/s00464-019-07347-z.","journal-title":"Surg Endosc"},{"issue":"5","key":"3369_CR53","doi-asserted-by":"publisher","first-page":"1820","DOI":"10.51253\/pafmj.v71i5.5773","volume":"71","author":"I Baloch","year":"2021","unstructured":"Baloch I, Umair B, Asghar A, Khan MI, Hanif MS. Operative outcomes in thoracoscopic-esophagectomy with two-lung ventilation in prone position. PAFMJ. 2021;71(5):1820\u20133. https:\/\/doi.org\/10.51253\/pafmj.v71i5.5773.","journal-title":"PAFMJ"},{"issue":"6","key":"3369_CR54","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1080\/13645706.2019.1660681","volume":"29","author":"M Zhao","year":"2020","unstructured":"Zhao M, Jiang T, Li M, et al. Video-assisted thoracoscopic total thymectomy: two-lung ventilation with artificial pneumothorax. Minim Invasive Ther Allied Technol. 2020;29(6):380\u20134. https:\/\/doi.org\/10.1080\/13645706.2019.1660681.","journal-title":"Minim Invasive Ther Allied Technol"}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03369-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-025-03369-3\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-025-03369-3.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T21:02:38Z","timestamp":1762030958000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-025-03369-3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,19]]},"references-count":54,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["3369"],"URL":"https:\/\/doi.org\/10.1007\/s12325-025-03369-3","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,19]]},"assertion":[{"value":"2 June 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"3 September 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 September 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Authors Silvia Coppola, Bruno Pastene, Isabella Fratti, Mert Sent\u00fcrk, Ebru Emre Demirel, and Davide Alberto Chiumello have no conflicts of interest to declare. Author Marc Leone is a member of the Editorial Board of\n                      Advances in Therapy\n                      . He was not involved in the selection of peer reviewers for the manuscript nor in any of the subsequent editorial decisions.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflicts of Interest"}},{"value":"This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}