{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T08:24:07Z","timestamp":1787387047914,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"},{"start":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T00:00:00Z","timestamp":1782777600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0"}],"funder":[{"name":"Opella"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Adv Ther"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s12325-026-03652-x","type":"journal-article","created":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T18:20:31Z","timestamp":1782843631000},"page":"4314-4324","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Exploring the Impact of Delivering Allergy Medication as Self-Care on Healthcare Greenhouse Gas Emissions in the United Kingdom"],"prefix":"10.1007","volume":"43","author":[{"given":"Patricia","family":"Pascual","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Caudwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie","family":"De Man","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Lally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Desrumaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Rigoine de Fougerolles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-8070-5426","authenticated-orcid":false,"given":"Fiona","family":"Adshead","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,6,30]]},"reference":[{"key":"3652_CR1","unstructured":"Sustainable Markets Initiative. Decarbonising patient care pathways. https:\/\/a.storyblok.com\/f\/109506\/x\/88fe7ea368\/smi-hstf-pcp-whitepaper.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR2","unstructured":"National Health Service. Delivering a net zero NHS. https:\/\/www.england.nhs.uk\/greenernhs\/a-net-zero-nhs\/. Accessed 12 May\u00a02026."},{"key":"3652_CR3","unstructured":"Global Self-Care Federation. The global social and economic value of self-care. https:\/\/www.selfcarefederation.org\/sites\/default\/files\/media\/documents\/2022-06\/FINAL_GSCF%20Socio-Economic%20Research%20Report%2022062022.pdf. Accessed 12 May\u00a02026."},{"issue":"1","key":"3652_CR4","doi-asserted-by":"publisher","first-page":"884","DOI":"10.1186\/s12889-025-21737-0","volume":"25","author":"S Barber","year":"2025","unstructured":"Barber S, Hayhoe B, Richardson S, Norton J, Karki M, El-Osta A. Drivers and barriers to promoting self-care in individuals living with multiple long-term health conditions: a cross-sectional online survey of health and care professionals. BMC Public Health. 2025;25(1):884.","journal-title":"BMC Public Health"},{"key":"3652_CR5","unstructured":"Association of the European Self-Care Industry. Self-care in Europe: economic and social impact on individuals and society. https:\/\/aesgp.eu\/content\/uploads\/2022\/01\/AESGP-Summary-Report-Self-Care-in-Europe-Economic-and-Social-Impact-on-Individuals-and-Society.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR6","unstructured":"PAGB. The economic impact of over-the-counter products in the UK. https:\/\/www.pagb.co.uk\/content\/uploads\/2023\/07\/20230712-Frontier-PAGB-OTC-Impact-Report-v1-0.pdf. Accessed 12 May\u00a02026."},{"issue":"1","key":"3652_CR7","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1038\/s41533-016-0001-y","volume":"27","author":"B Lipworth","year":"2017","unstructured":"Lipworth B, Newton J, Ram B, Small I, Schwarze J. An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel. NPJ Prim Care Respir Med. 2017;27(1):3.","journal-title":"NPJ Prim Care Respir Med"},{"key":"3652_CR8","unstructured":"Office for National Statistics. Population estimates time series dataset. https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/populationandmigration\/populationestimates\/datasets\/populationestimatestimeseriesdataset\/current. Accessed 12 May\u00a02026."},{"key":"3652_CR9","unstructured":"Allergy UK. Thunderstorm asthma. https:\/\/www.allergyuk.org\/news\/thunderstorm-asthma\/. Accessed 12 May\u00a02026."},{"key":"3652_CR10","unstructured":"United States Environmental Protection Agency. Particle pollution and your patients' health. https:\/\/www.epa.gov\/pmcourse\/particle-pollution-and-respiratory-effects. Accessed 12 May\u00a02026."},{"issue":"1","key":"3652_CR11","doi-asserted-by":"publisher","first-page":"1234","DOI":"10.1038\/s41467-022-28764-0","volume":"13","author":"Y Zhang","year":"2022","unstructured":"Zhang Y, Steiner AL. Projected climate-driven changes in pollen emission season length and magnitude over the continental United States. Nat Commun. 2022;13(1):1234.","journal-title":"Nat Commun"},{"issue":"2","key":"3652_CR12","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/j.jaci.2004.11.047","volume":"115","author":"M Riedl","year":"2005","unstructured":"Riedl M, Diaz-Sanchez D. Biology of diesel exhaust effects on respiratory function. J Allergy Clin Immunol. 2005;115(2):221\u20138.","journal-title":"J Allergy Clin Immunol"},{"key":"3652_CR13","unstructured":"National Wildlife Federation. Extreme allergies and global warming. https:\/\/aafa.org\/wp-content\/uploads\/2022\/08\/extreme-allergies-global-warming-report-2010.pdf. Accessed 12 May\u00a02026."},{"issue":"3","key":"3652_CR14","doi-asserted-by":"publisher","first-page":"e124","DOI":"10.1016\/S2542-5196(19)30015-4","volume":"3","author":"LH Ziska","year":"2019","unstructured":"Ziska LH, Makra L, Harry SK, et al. Temperature-related changes in airborne allergenic pollen abundance and seasonality across the northern hemisphere: a retrospective data analysis. Lancet Planet Health. 2019;3(3):e124\u201331.","journal-title":"Lancet Planet Health"},{"issue":"6","key":"3652_CR15","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1029\/2020GL091753","volume":"48","author":"J Wang","year":"2021","unstructured":"Wang J, Guan Y, Wu L, Guan X, Cai W, Huang J. Changing lengths of the four seasons by global warming. Geophys Res Lett. 2021;48(6):1\u20139.","journal-title":"Geophys Res Lett"},{"issue":"10363","key":"3652_CR16","doi-asserted-by":"publisher","first-page":"1619","DOI":"10.1016\/S0140-6736(22)01540-9","volume":"400","author":"M Romanello","year":"2022","unstructured":"Romanello M, Di Napoli C, Drummond P, et al. The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels. Lancet. 2022;400(10363):1619\u201354.","journal-title":"Lancet"},{"issue":"6","key":"3652_CR17","doi-asserted-by":"publisher","first-page":"891","DOI":"10.1046\/j.1365-2222.2000.00914.x","volume":"30","author":"P Van Cauwenberge","year":"2000","unstructured":"Van Cauwenberge P, Juniper EF. Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120\u00a0mg, loratadine 10\u00a0mg and placebo administered once daily for the treatment of seasonal allergic rhinitis. Clin Exp Allergy. 2000;30(6):891\u20139.","journal-title":"Clin Exp Allergy"},{"key":"3652_CR18","unstructured":"World Resources Institute. The Greenhouse gas protocol: a corporate and reporting standard. https:\/\/ghgprotocol.org\/sites\/default\/files\/standards\/ghg-protocol-revised.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR19","unstructured":"Environmental Resources Management. Greenhouse gas accounting sector guidance for pharmaceutical products and medical devices. https:\/\/ghgprotocol.org\/sites\/default\/files\/tools\/Summary-Document_Pharmaceutical-Product-and-Medical-Device-GHG-Accounting_November-2012.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR20","unstructured":"Sustainable Healthcare Coalition. Sustainable care pathways guidance. https:\/\/shcoalition.org\/sustainable-care-pathways-guidance\/. Accessed 12 May\u00a02026."},{"issue":"2","key":"3652_CR21","doi-asserted-by":"publisher","first-page":"e84","DOI":"10.1016\/S2542-5196(20)30271-0","volume":"5","author":"I Tennison","year":"2021","unstructured":"Tennison I, Roschnik S, Ashby B, et al. Health care\u2019s response to climate change: a carbon footprint assessment of the NHS in England. Lancet Planet Health. 2021;5(2):e84\u201392.","journal-title":"Lancet Planet Health"},{"key":"3652_CR22","unstructured":"Coalition for Sustainable Pharmaceuticals and Medical Devices (CSPM). Care pathways: guidance on appraising sustainability. https:\/\/shcoalition.org\/wp-content\/uploads\/2019\/10\/Sustainable-Care-Pathways-Guidance-Summary-Oct-2015.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR23","unstructured":"Northern Ireland Statistics and Research Agency. Registrar general annual report 2019 births. https:\/\/www.nisra.gov.uk\/publications\/registrar-general-annual-report-2019-births. Accessed 12 May\u00a02026."},{"key":"3652_CR24","unstructured":"National Records of Scotland. The registrar general's annual review of demographic trends. https:\/\/www.nrscotland.gov.uk\/files\/statistics\/rgar\/2019\/Pages\/bir-sec.html. Accessed 12 May\u00a02026."},{"key":"3652_CR25","unstructured":"Office for National Statistics. Birth characteristics in England and Wales: 2019. https:\/\/www.ons.gov.uk\/peoplepopulationandcommunity\/birthsdeathsandmarriages\/livebirths\/bulletins\/birthcharacteristicsinenglandandwales\/2019#:~:text=Since%202010%2C%20the%20percentage%20of,point%20to%207.8%25%20in%202019. Accessed 12 May\u00a02026."},{"key":"3652_CR26","unstructured":"PAGB. Take care \u2013 of yourself and the NHS. https:\/\/www.selfcareforum.org\/wp-content\/uploads\/2024\/03\/PAGB-Self-Care-Survey-2023.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR27","unstructured":"Department for Transport. National Travel Survey: 2019. https:\/\/www.gov.uk\/government\/statistics\/national-travel-survey-2019. Accessed 12 May\u00a02026."},{"key":"3652_CR28","unstructured":"KettleMag. How far do you have to travel to pick up medical prescriptions? https:\/\/kettlemag.co.uk\/how-far-do-you-have-to-travel-to-pick-up-medical-prescriptions\/. Accessed 12 May\u00a02026."},{"key":"3652_CR29","unstructured":"British Broadcasting Corporation. Climate change: Should you fly, drive or take the train? https:\/\/www.bbc.com\/news\/science-environment-49349566. Accessed 12 May\u00a02026."},{"key":"3652_CR30","unstructured":"UK Health Security Agency. GP in hours syndromic surveillance system bulletin (England) (2023\u00a0week\u00a015). https:\/\/assets.publishing.service.gov.uk\/media\/643ffa1022ef3b000f66f52e\/UKHSA_GPinHoursEngBulletin2023Wk15.pdf. Accessed 12 May\u00a02026."},{"issue":"2","key":"3652_CR31","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12209","volume":"13","author":"S Moitra","year":"2023","unstructured":"Moitra S, Simoni M, Baldacci S, et al. Symptom control and health-related quality of life in allergic rhinitis with and without comorbid asthma: a multicentre European study. Clin Transl Allergy. 2023;13(2):e12209.","journal-title":"Clin Transl Allergy"},{"key":"3652_CR32","unstructured":"National Institute for Health and Care Excellence. Asthma inhalers and climate change. https:\/\/www.nice.org.uk\/guidance\/ng80\/resources\/asthma-inhalers-and-climate-change-patient-decision-aid-pdf-6727144573. Accessed 12 May\u00a02026."},{"key":"3652_CR33","unstructured":"PrescQIPP. Inhaler carbon footprint. https:\/\/www.prescqipp.info\/umbraco\/surface\/authorisedmediasurface\/index?url=%2fmedia%2f5719%2f295-inhaler-carbon-footprint-22.pdf. Accessed 12 May\u00a02026."},{"key":"3652_CR34","unstructured":"UK Health Security Agency. Environmental policy. https:\/\/www.gov.uk\/government\/publications\/sustainability-in-ukhsa\/environmental-policy. Accessed 12 May\u00a02026."}],"container-title":["Advances in Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-026-03652-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12325-026-03652-x","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12325-026-03652-x.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,22]],"date-time":"2026-08-22T08:04:32Z","timestamp":1787385872000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12325-026-03652-x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":34,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["3652"],"URL":"https:\/\/doi.org\/10.1007\/s12325-026-03652-x","relation":{},"ISSN":["0741-238X","1865-8652"],"issn-type":[{"value":"0741-238X","type":"print"},{"value":"1865-8652","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,30]]},"assertion":[{"value":"26 March 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 May 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"30 June 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Patricia Pascual and Amanda Caudwell are employees of Opella. Thierry Rigoine de Fougerolles, Stephanie De Man, and Edouard Desrumaux are employees of CVA, and Michael Lally was an employee of CVA at the time of the analysis and is now an employee of HarbourVest Partners. CVA received consulting fees from Opella to conduct the research. Fiona Adshead declares no conflict of interest.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Ethical approval was not required for this study, which did not involve any animals or human participants.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}