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All other authors; Changjun Su, Jiucheng Shen, Kaida Guo, Jing Wang, Zhijun Wang, Shiyuan Gao, Qiaojun Wang, Fei Han and Rui Chen declare no conflicts of interest.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The parent randomized clinical trial was approved by the institutional review board of Peking University Sixth Hospital ([2023] Ethics Review No. 22-1) and by the 25 independent ethics committees at all other participating sites. The ethical approval numbers for each study site are summarized in Table\u00a0\n                      \n                      .","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}