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Donald L. Bliwise acts as a consultant for Ferring, Idorsia, and Merck. Duygu Alpan and Patricia Koochaki are employees of ICON Plc which received funding from Idorsia Pharmaceuticals Ltd for this analysis. Michael Meinel, Antonio Olivieri, Racheal Rowles and Annyesha Satapathy are employees of Idorsia Pharmaceuticals Ltd. Katharina Lederer has no conflicts of interest to disclose.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All subjects gave written informed consent.\u00a0Ethics approval for this study\u00a0were\u00a0obtained\u00a0from\u00a0Advarra\u00a0(in the US),\u00a0Bundesinstitut\u00a0f\u00fcr Arzneimittel und\u00a0Medizinprodukte\u00a0(in Germany) and\u00a0Medicinal Product Research Ethics Committee of Parc de Salut MAR\u00a0(In\u00a0Spain).\u00a0Detailed ethical approval information is available in the Supplementary Material.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"IDSIQ\n                      \u00a9\n                      \u00a02020, University of Pittsburgh. All rights reserved. IDSIQ-14 derivative was created, and distributed by Idorsia Pharmaceuticals Ltd under license in 2020. IDSIQ is further a registered trademark of Idorsia Pharmaceuticals Ltd. The Insomnia Severity Index (ISI) is a copyrighted instrument (\u00a9 Morin, C.M.) and was used with permission. A license for its use in this clinical study (ID-078A401; Idorsia Pharmaceuticals Ltd.) was obtained via Mapi Research Trust.","order":3,"name":"Ethics","label":"Permissions and Licenses","group":{"name":"EthicsHeading","label":"Declarations"}}]}}