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Uazman Alam has also received investigator-led funding from Procter & Gamble, GSK, and Axonis Therapeutics and is a council member of the Royal Society of Medicine\u2019s Vascular, Lipid & Metabolic Medicine Section. Uazman Alam is supported by the National Institute for Health Research Applied Research Collaboration North West Coast (ARC NWC). The views expressed in this publication are those of the author(s) and not necessarily those of the National Institute for Health Research or the Department of Health and Social Care. Uazman Alam is an Editorial Board member of\n                      Diabetes and Therapy\n                      . Uazman Alam was not involved in the selection of peer reviewers for the manuscript or any of the subsequent editorial decisions. Aikaterini Eleftheriadou, Matthew Anson, Zien Fozo, Shehzaad Khan and Khalid Al-Hourani have no conflicts of interest to disclose.","order":1,"name":"Ethics","label":"Conflict of Interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study used de-identified data obtained from the TriNetX global federated health research network. Data were de-identified in accordance with the Health Insurance Portability and Accountability Act (HIPAA) \u00a7164.514(b)(1) through a Qualified Expert Determination. As the study did not involve identifiable human participants, it was not considered human subjects research and institutional review board approval was not required.","order":2,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Aikaterini Eleftheriadou was affiliated with Frimley Park Hospital at the time the study was conducted and has since moved to the Department of Trauma and Orthopaedics, Ashford and St Peter\u2019s Hospitals, Chertsey, Surrey, UK.","order":3,"name":"Ethics","label":"Affiliations","group":{"name":"EthicsHeading","label":"Declarations"}}]}}