{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T20:04:35Z","timestamp":1762459475690,"version":"3.37.3"},"reference-count":14,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T00:00:00Z","timestamp":1495584000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1007\/s12328-017-0749-9","type":"journal-article","created":{"date-parts":[[2017,5,24]],"date-time":"2017-05-24T05:18:40Z","timestamp":1495603120000},"page":"357-360","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Negative conversion of high serum p53 antibody titers in a patient with gastric cancer at 31\u00a0months after surgery"],"prefix":"10.1007","volume":"10","author":[{"given":"Kenji","family":"Murayama","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuki","family":"Nanami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takashi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Oshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Yajima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuo","family":"Nemoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1990-8217","authenticated-orcid":false,"given":"Hideaki","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2017,5,24]]},"reference":[{"key":"749_CR1","first-page":"41","volume":"99","author":"G Shiota","year":"1998","unstructured":"Shiota G, Ishida M, Noguchi N, et al. Clinical significance of serum p53 antibody in patients with gastric cancer. Res Commun Mol Pathol Pharmacol. 1998;99:41\u201351.","journal-title":"Res Commun Mol Pathol Pharmacol"},{"key":"749_CR2","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1007\/s10120-005-0337-4","volume":"8","author":"K Shimizu","year":"2005","unstructured":"Shimizu K, Ueda Y, Yamagishi H. Titration of serum p53 antibodies in patients with gastric cancer: a single-institute study of 40 patients. Gastric Cancer. 2005;8:214\u20139.","journal-title":"Gastric Cancer"},{"key":"749_CR3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000030057","volume":"20","author":"K Nakajima","year":"1999","unstructured":"Nakajima K, Suzuki T, Shimada H, et al. Detection of preoperative serum anti-p53 antibodies in gastric cancer. Tumour Biol. 1999;20:147\u201352.","journal-title":"Tumour Biol"},{"key":"749_CR4","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/s00268-008-9821-4","volume":"33","author":"H Shimada","year":"2009","unstructured":"Shimada H, Shiratori T, Takeda A, et al. Perioperative changes of serum p53 antibody titer is a predictor for survival in patients with esophageal squamous cell carcinoma. World J Surg. 2009;33:272\u20137.","journal-title":"World J Surg"},{"key":"749_CR5","doi-asserted-by":"crossref","first-page":"1957","DOI":"10.1007\/s00595-013-0787-y","volume":"44","author":"H Shimada","year":"2014","unstructured":"Shimada H, Nagata M, Cho A, et al. Long-term monitoring of serum p53 antibody after neoadjuvant chemotherapy and surgery for esophageal adenocarcinoma: report of a case. Surg Today. 2014;44:1957\u201361.","journal-title":"Surg Today"},{"key":"749_CR6","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1002\/(SICI)1097-0142(19990115)85:2<302::AID-CNCR6>3.0.CO;2-6","volume":"85","author":"Y Maehara","year":"1999","unstructured":"Maehara Y, Kakeji Y, Watanabe A, et al. Clinical implications of serum anti-p53 antibodies for patients with gastric carcinoma. Cancer. 1999;85:302\u20138.","journal-title":"Cancer"},{"key":"749_CR7","doi-asserted-by":"crossref","first-page":"2243","DOI":"10.1002\/ijc.28807","volume":"136","author":"S Werner","year":"2015","unstructured":"Werner S, Chen H, Tao S, et al. Systematic review: serum autoantibodies in the early detection of gastric cancer. Int J Cancer. 2015;136:2243\u201352.","journal-title":"Int J Cancer"},{"key":"749_CR8","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1007\/s00595-016-1464-8","volume":"47","author":"R Tokunaga","year":"2017","unstructured":"Tokunaga R, Sakamoto Y, Nakagawa S, et al. The utility of tumor marker combination, including\u00a0serum\u00a0p53\u00a0antibody, in\u00a0colorectal cancer\u00a0treatment. Surg Today. 2017;47:636\u201342.","journal-title":"Surg Today"},{"key":"749_CR9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s12328-016-0633-z","volume":"9","author":"T Suzuki","year":"2016","unstructured":"Suzuki T, Shimada H, Ushigome M, et al. Three-year monitoring of\u00a0serum\u00a0p53\u00a0antibody\u00a0during chemotherapy and surgery for stage IV rectal\u00a0cancer. Clin J Gastroenterol. 2016;9:55\u20138.","journal-title":"Clin J Gastroenterol"},{"key":"749_CR10","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1002\/cncr.11092","volume":"97","author":"H Shimada","year":"2003","unstructured":"Shimada H, Ochiai T, Nomura F. Japan p53 Antibody Research Group. Titration of serum p53 antibodies in 1,085 patients with various types of malignant tumors: a multiinstitutional analysis by the Japan p53 Antibody Research Group. Cancer. 2003;97:682\u20139.","journal-title":"Cancer"},{"key":"749_CR11","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s10120-011-0041-5","volume":"14","author":"Japanese Gastric Cancer Association","year":"2011","unstructured":"Japanese Gastric Cancer Association: Japanese classification of gastric carcinoma: 3rd English edition. Gastric Cancer. 2011;14:101\u201312.","journal-title":"Gastric Cancer"},{"key":"749_CR12","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1007\/s10120-013-0259-5","volume":"17","author":"H Shimada","year":"2014","unstructured":"Shimada H, Noie T, Ohashi M, et al. Clinical significance of serum tumor markers for gastric cancer: a systematic review of literature by the Task Force of the Japanese Gastric Cancer Association. Gastric Cancer. 2014;17:26\u201333.","journal-title":"Gastric Cancer"},{"key":"749_CR13","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1067\/msy.2002.125307","volume":"132","author":"H Shimada","year":"2002","unstructured":"Shimada H, Nabeya Y, Okazumi S, et al. Prognostic significance of serum p53 antibody in patients with esophageal squamous cell carcinoma. Surgery. 2002;132:41\u20137.","journal-title":"Surgery"},{"key":"749_CR14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1172\/JCI106279","volume":"49","author":"A Morell","year":"1970","unstructured":"Morell A, Terry WD, Waldmann TA. Metabolic properties of IgG subclasses in man. J Clin Invest. 1970;49:673\u201380.","journal-title":"J Clin Invest"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12328-017-0749-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-017-0749-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-017-0749-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,7,18]],"date-time":"2017-07-18T13:23:55Z","timestamp":1500384235000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12328-017-0749-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5,24]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["749"],"URL":"https:\/\/doi.org\/10.1007\/s12328-017-0749-9","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"type":"print","value":"1865-7257"},{"type":"electronic","value":"1865-7265"}],"subject":[],"published":{"date-parts":[[2017,5,24]]}}}