{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,21]],"date-time":"2025-06-21T20:22:16Z","timestamp":1750537336388,"version":"3.37.3"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T00:00:00Z","timestamp":1591660800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T00:00:00Z","timestamp":1591660800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1007\/s12328-020-01147-y","type":"journal-article","created":{"date-parts":[[2020,6,9]],"date-time":"2020-06-09T22:02:41Z","timestamp":1591740161000},"page":"766-770","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Double small bowel cancers leading to the diagnosis of Lynch syndrome with germline MSH6 mutation in an elderly patient"],"prefix":"10.1007","volume":"13","author":[{"given":"Sae","family":"Ohwada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9003-9846","authenticated-orcid":false,"given":"Kentaro","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoe","family":"Kazama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kei","family":"Mitsuhashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Ichiyanagi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Nakachi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiro-o","family":"Yamano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takayuki","family":"Nobuoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuya","family":"Ito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wataru","family":"Sasao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Nakase","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,6,9]]},"reference":[{"key":"1147_CR1","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1097\/00054725-200401000-00005","volume":"10","author":"CA Solem","year":"2004","unstructured":"Solem CA, Harmsen WS, Zinsmeister AR, et al. Small intestinal adenocarcinoma in Crohn\u2019s disease: a case-control study. Inflamm Bowel Dis. 2004;10:32\u20135.","journal-title":"Inflamm Bowel Dis"},{"key":"1147_CR2","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1056\/NEJMra071600","volume":"357","author":"PH Green","year":"2007","unstructured":"Green PH, Cellier C. Celiac disease. N Engl J Med. 2007;357:1731\u201343.","journal-title":"N Engl J Med"},{"key":"1147_CR3","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1038\/ajg.2014.435","volume":"110","author":"S Syngal","year":"2015","unstructured":"Syngal S, Brand RE, Church JM, et al. ACG clinical guideline: genetic testing and management of hereditary gastrointestinal cancer syndromes. Am J Gastroenterol. 2015;110:233\u201362.","journal-title":"Am J Gastroenterol"},{"key":"1147_CR4","doi-asserted-by":"publisher","first-page":"1198","DOI":"10.1136\/gut.2006.118299","volume":"56","author":"GL ten Kate","year":"2007","unstructured":"ten Kate GL, Kleibeuker JH, Nagengast FM, et al. Is surveillance of the small bowel indicated for Lynch syndrome families? Gut. 2007;56:1198\u2013201.","journal-title":"Gut"},{"key":"1147_CR5","doi-asserted-by":"publisher","first-page":"2304","DOI":"10.1001\/jama.2011.743","volume":"305","author":"V Bonadona","year":"2011","unstructured":"Bonadona V, Bonaiti B, Olschwang S, et al. Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome. JAMA. 2011;305:2304\u201310.","journal-title":"JAMA"},{"key":"1147_CR6","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1093\/jnci\/djs351","volume":"104","author":"AK Win","year":"2012","unstructured":"Win AK, Lindor NM, Young JP, et al. Risks of primary extracolonic cancers following colorectal cancer in Lynch syndrome. J Natl Cancer Inst. 2012;104:1363\u201372.","journal-title":"J Natl Cancer Inst"},{"key":"1147_CR7","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1186\/s13053-018-0098-9","volume":"16","author":"M Karimi","year":"2018","unstructured":"Karimi M, von Salome J, Aravidis C, et al. A retrospective study of extracolonic, non-endometrial cancer in Swedish Lynch syndrome families. Hered Cancer Clin Pract. 2018;16:16.","journal-title":"Hered Cancer Clin Pract"},{"key":"1147_CR8","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1097\/SLA.0b013e31818e4641","volume":"249","author":"KY Bilimoria","year":"2009","unstructured":"Bilimoria KY, Bentrem DJ, Wayne JD, et al. Small bowel cancer in the United States. Changes in epidemiology, treatment, and survival over the last 20 years. Ann Surg. 2009;249:63\u201371.","journal-title":"Ann Surg"},{"key":"1147_CR9","unstructured":"National institute of health. Cancer stat facts; small intestine cancer. Surveillance, epidemiology and end results program https:\/\/seer.cancer.gov\/statfacts\/html\/smint.html Accessed on 29 Feb 2020."},{"key":"1147_CR10","doi-asserted-by":"publisher","first-page":"181","DOI":"10.1007\/s00535-019-01636-z","volume":"55","author":"AM Bouvier","year":"2020","unstructured":"Bouvier AM, Robaszkiewicz M, Jooste V, et al. Trends in incidence of small bowel cancer according to histology: a population-based study. J Gastroenterol. 2020;55:181\u20138.","journal-title":"J Gastroenterol"},{"key":"1147_CR11","unstructured":"National comprehensive cancer network. NCCN clinical practice guidelines in oncology. Genetic\/familial high-risk assessment: colorectal version 3.2019 https:\/\/www.nccn.org\/professionals\/physician_gls\/pdf\/genetics_colon.pdf Accessed on 29 Feb 2020."},{"key":"1147_CR12","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1055\/a-1016-4977","volume":"51","author":"ME van Leerdam","year":"2019","unstructured":"van Leerdam ME, Roos VH, van Hooft JE, et al. Endoscopic management of Lynch syndrome and of familial risk of colorectal cancer: European society of gastrointestinal endoscopy (ESGE) guideline. Endoscopy. 2019;51:1082\u201393.","journal-title":"Endoscopy"},{"key":"1147_CR13","doi-asserted-by":"publisher","first-page":"1057","DOI":"10.1055\/s-0030-1255742","volume":"42","author":"JC Saurin","year":"2010","unstructured":"Saurin JC, Pilleul F, Soussan EB, et al. Small-bowel capsule endoscopy diagnoses early and advanced neoplasms in asymptomatic patients with Lynch syndrome. Endoscopy. 2010;42:1057\u201362.","journal-title":"Endoscopy"},{"key":"1147_CR14","doi-asserted-by":"publisher","first-page":"1578","DOI":"10.1136\/gutjnl-2014-307348","volume":"64","author":"JF Haanstra","year":"2015","unstructured":"Haanstra JF, Al-Toma A, Dekker E, et al. Prevalence of small-bowel neoplasia in Lynch syndrome assessed by video capsule endoscopy. Gut. 2015;64:1578\u201383.","journal-title":"Gut"},{"key":"1147_CR15","doi-asserted-by":"publisher","first-page":"E622","DOI":"10.1055\/s-0043-111723","volume":"5","author":"JF Haanstra","year":"2017","unstructured":"Haanstra JF, Al-Toma A, Dekker E, et al. Incidence of small bowel neoplasiain Lynch syndrome assessed by video capsule endoscopy. Endosc Int Open. 2017;5:E622\u2013E626626.","journal-title":"Endosc Int Open"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-020-01147-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12328-020-01147-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-020-01147-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T05:38:58Z","timestamp":1623217138000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12328-020-01147-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,9]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["1147"],"URL":"https:\/\/doi.org\/10.1007\/s12328-020-01147-y","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"type":"print","value":"1865-7257"},{"type":"electronic","value":"1865-7265"}],"subject":[],"published":{"date-parts":[[2020,6,9]]},"assertion":[{"value":"17 March 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 May 2020","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 June 2020","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"All authors declare no conflict of interest for this study.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human Rights"}},{"value":"Informed consent was obtained from all patients for being included in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed Consent"}}]}}