{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T16:45:44Z","timestamp":1781801144818,"version":"3.54.5"},"reference-count":25,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T00:00:00Z","timestamp":1675987200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1007\/s12328-023-01769-y","type":"journal-article","created":{"date-parts":[[2023,2,10]],"date-time":"2023-02-10T16:36:03Z","timestamp":1676046963000},"page":"366-371","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Mixed high-grade serous and large cell neuroendocrine carcinoma arising from rectal endometriosis 11\u00a0years after hysterectomy"],"prefix":"10.1007","volume":"16","author":[{"given":"Takumi","family":"Yanagita","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9815-1557","authenticated-orcid":false,"given":"Takuto","family":"Hikichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Waragai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoto","family":"Abe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choichiro","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromi","family":"Kumakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masao","family":"Kobayakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromasa","family":"Ohira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,10]]},"reference":[{"key":"1769_CR1","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1097\/00000478-200104000-00003","volume":"25","author":"RK Yantiss","year":"2001","unstructured":"Yantiss RK, Clement PB, Young RH. Endometriosis of the intestinal tract: a study of 44 cases of a disease that may cause diverse challenges in clinical and pathologic evaluation. Am J Surg Pathol. 2001;25:445\u201354.","journal-title":"Am J Surg Pathol"},{"key":"1769_CR2","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1111\/j.1471-0528.1960.tb09211.x","volume":"67","author":"CH Macafee","year":"1960","unstructured":"Macafee CH, Greer HL. Intestinal endometriosis. A report of 29 cases and a survey of the literature. J Obstet Gynaecol Br Emp. 1960;67:539\u201355.","journal-title":"J Obstet Gynaecol Br Emp"},{"key":"1769_CR3","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.jmig.2006.07.009","volume":"14","author":"IK Orbuch","year":"2007","unstructured":"Orbuch IK, Reich H, Orbuch M, et al. Laparoscopic treatment of recurrent small bowel obstruction secondary to ileal endometriosis. J Minim Invasive Gynecol. 2007;14:113\u20135.","journal-title":"J Minim Invasive Gynecol"},{"key":"1769_CR4","first-page":"405","volume":"72","author":"M Paksoy","year":"2005","unstructured":"Paksoy M, Karabi\u00e7ak I, Ayan F, et al. Intestinal obstruction due to rectal endometriosis. Mt Sinai J Med. 2005;72:405\u20138.","journal-title":"Mt Sinai J Med"},{"key":"1769_CR5","first-page":"1023","volume":"75","author":"JM Heaps","year":"1990","unstructured":"Heaps JM, Nieberg RK, Berek JS. Malignant neoplasms arising in endometriosis. Obstet Gynecol. 1990;75:1023\u20138.","journal-title":"Obstet Gynecol"},{"key":"1769_CR6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1097\/pgp.0b013e31806219c5","volume":"27","author":"NJ Mulvany","year":"2008","unstructured":"Mulvany NJ, Allen DG. Combined large cell neuroendocrine and endometrioid carcinoma of the endometrium. Int J Gynecol Pathol. 2008;27:49\u201357.","journal-title":"Int J Gynecol Pathol"},{"key":"1769_CR7","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1097\/PGP.0b013e31815de006","volume":"27","author":"J Albores-Saavedra","year":"2008","unstructured":"Albores-Saavedra J, Martinez-Benitez B, Luevano E. Small cell carcinomas and large cell neuroendocrine carcinomas of the endometrium and cervix: polypoid tumors and those arising in polyps may have a favorable prognosis. Int J Gynecol Pathol. 2008;27:333\u20139.","journal-title":"Int J Gynecol Pathol"},{"key":"1769_CR8","doi-asserted-by":"publisher","first-page":"1821","DOI":"10.5858\/132.11.1821","volume":"132","author":"L Posligua","year":"2008","unstructured":"Posligua L, Malpica A, Liu J, et al. Combined large cell neuroendocrine carcinoma and papillary serous carcinoma of the endometrium with pagetoid spread. Arch Pathol Lab Med. 2008;132:1821\u20134.","journal-title":"Arch Pathol Lab Med"},{"key":"1769_CR9","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1016\/j.prp.2009.12.008","volume":"206","author":"T Terada","year":"2010","unstructured":"Terada T. Large cell neuroendocrine carcinoma with sarcomatous changes of the endometrium: a case report with immunohistochemical studies and molecular genetic study of KIT and PDGFRA. Pathol Res Pract. 2010;206:420\u20135.","journal-title":"Pathol Res Pract"},{"key":"1769_CR10","doi-asserted-by":"publisher","first-page":"211","DOI":"10.4103\/0973-1482.82942","volume":"7","author":"KK Deodhar","year":"2011","unstructured":"Deodhar KK, Kerkar RA, Suryawanshi P, et al. Large cell neuroendocrine carcinoma of the endometrium: an extremely uncommon diagnosis, but worth the efforts. J Cancer Res Ther. 2011;7:211\u20133.","journal-title":"J Cancer Res Ther"},{"key":"1769_CR11","doi-asserted-by":"publisher","DOI":"10.4081\/rt.2011.e41","volume":"3","author":"S Shahabi","year":"2011","unstructured":"Shahabi S, Pellicciotta I, Hou J, et al. Clinical utility of chromogranin A and octreotide in large cell neuro endocrine carcinoma of the uterine corpus. Rare Tumors. 2011;3: e41.","journal-title":"Rare Tumors"},{"key":"1769_CR12","doi-asserted-by":"publisher","DOI":"10.4081\/rt.2012.4098","volume":"4","author":"N Makihara","year":"2012","unstructured":"Makihara N, Maeda T, Nishimura M, et al. Large cell neuroendocrine carcinoma originating from the uterine endometrium: a report on magnetic resonance features of 2 cases with very rare and aggressive tumor. Rare Tumors. 2012;4: e37.","journal-title":"Rare Tumors"},{"key":"1769_CR13","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1177\/1066896920901764","volume":"28","author":"G Rivera","year":"2020","unstructured":"Rivera G, Niu S, Chen H, et al. Collision tumor of endometrial large cell neuroendocrine carcinoma and low-grade endometrial stromal sarcoma: a case report and review of the literature. Int J Surg Pathol. 2020;28:569\u201373.","journal-title":"Int J Surg Pathol"},{"key":"1769_CR14","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1016\/j.ijscr.2013.04.027","volume":"4","author":"ML Nguyen","year":"2013","unstructured":"Nguyen ML, Han L, Minors AM, et al. Rare large cell neuroendocrine tumor of the endometrium: a case report and review of the literature. Int J Surg Case Rep. 2013;4:651\u20135.","journal-title":"Int J Surg Case Rep"},{"key":"1769_CR15","first-page":"109","volume":"25","author":"Y Erhan","year":"2004","unstructured":"Erhan Y, Dikmen Y, Yucebilgin MS, et al. Large cell neuroendocrine carcinoma of the uterine corpus metastatic to brain and lung: case report and review of the literature. Eur J Gynaecol Oncol. 2004;25:109\u201312.","journal-title":"Eur J Gynaecol Oncol"},{"key":"1769_CR16","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1097\/PAS.0000000000000633","volume":"40","author":"CE Pocrnich","year":"2016","unstructured":"Pocrnich CE, Ramalingam P, Euscher ED, et al. Neuroendocrine carcinoma of the endometrium: a clinicopathologic study of 25 cases. Am J Surg Pathol. 2016;40:577\u201386.","journal-title":"Am J Surg Pathol"},{"key":"1769_CR17","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.tjog.2017.12.025","volume":"57","author":"YA Tu","year":"2018","unstructured":"Tu YA, Chen YL, Lin MC, et al. Large cell neuroendocrine carcinoma of the endometrium: a case report and literature review. Taiwan J Obstet Gynecol. 2018;57:144\u20139.","journal-title":"Taiwan J Obstet Gynecol"},{"key":"1769_CR18","doi-asserted-by":"publisher","first-page":"96","DOI":"10.1016\/j.gore.2019.03.006","volume":"28","author":"C Jenny","year":"2019","unstructured":"Jenny C, Kimball K, Kilgore L, et al. Large cell neuroendocrine carcinoma of the endometrium: a report and review of the literature. Gynecol Oncol Rep. 2019;28:96\u2013100.","journal-title":"Gynecol Oncol Rep"},{"key":"1769_CR19","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000016433","volume":"98","author":"R Hu","year":"2019","unstructured":"Hu R, Jiang J, Song G, et al. Mixed large and small cell neuroendocrine carcinoma of the endometrium with serous carcinoma: a case report and literature review. Medicine. 2019;98: e16433.","journal-title":"Medicine"},{"key":"1769_CR20","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-234977","volume":"13","author":"LE Hardy","year":"2020","unstructured":"Hardy LE, Chaudry Z, Wan K, et al. Primary mixed large cell neuroendocrine and high grade serous carcinoma of the endometrium. BMJ Case Rep. 2020;13: e234977.","journal-title":"BMJ Case Rep"},{"key":"1769_CR21","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1053\/hp.2000.6712","volume":"31","author":"RE Slavin","year":"2000","unstructured":"Slavin RE, Krum R, Van Dinh T. Endometriosis-associated intestinal tumors: a clinical and pathological study of 6 cases with a review of the literature. Hum Pathol. 2000;31:456\u201363.","journal-title":"Hum Pathol"},{"key":"1769_CR22","doi-asserted-by":"publisher","DOI":"10.1007\/s11912-017-0617-2","author":"BE Howitt","year":"2017","unstructured":"Howitt BE, Kelly P, McCluggage WG. Pathology of neuroendocrine tumours of the female genital tract. Curr Oncol Rep. 2017. https:\/\/doi.org\/10.1007\/s11912-017-0617-2.","journal-title":"Curr Oncol Rep"},{"key":"1769_CR23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1001\/archsurg.1925.01120100007001","volume":"10","author":"JA Sampson","year":"1925","unstructured":"Sampson JA. Endometrial carcinoma of the ovary, arising in endometrial tissue in that organ. Arch Surg. 1925;10:1\u201372.","journal-title":"Arch Surg"},{"key":"1769_CR24","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s13691-016-0263-9","volume":"6","author":"M Ariura","year":"2017","unstructured":"Ariura M, Kasajima R, Miyagi Y, et al. Combined large cell neuroendocrine carcinoma and endometrioid carcinoma of the endometrium: a shared gene mutation signature between the two histological components. Int Cancer Conf J. 2017;6:11\u20135.","journal-title":"Int Cancer Conf J"},{"key":"1769_CR25","first-page":"482","volume":"18","author":"MA Abu","year":"1997","unstructured":"Abu MA, Sinha P, Totoe L, et al. Endometrial cancer thirteen years after total abdominal hysterectomy and bilateral salpingo-oophorectomy and hormone replacement therapy: a case report. Eur J Gynaecol Oncol. 1997;18:482\u20133.","journal-title":"Eur J Gynaecol Oncol"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-023-01769-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12328-023-01769-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-023-01769-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,20]],"date-time":"2023-05-20T13:12:25Z","timestamp":1684588345000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12328-023-01769-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,10]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["1769"],"URL":"https:\/\/doi.org\/10.1007\/s12328-023-01769-y","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"value":"1865-7257","type":"print"},{"value":"1865-7265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,10]]},"assertion":[{"value":"29 July 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 January 2023","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 February 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Takumi Yanagita, Takuto Hikichi, Yuichi Waragai, Hiroshi Shimizu, Yuta Takahashi, Naoto Abe, Choichiro Hashimoto, Hiromi Kumakawa, Masao Kobayakawa, Hiromasa Ohira declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Informed consent was obtained from this patient for being included in the paper.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}