{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:05:06Z","timestamp":1779966306319,"version":"3.53.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s12328-026-02304-5","type":"journal-article","created":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T06:58:51Z","timestamp":1773039531000},"page":"522-528","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diffuse duodenitis in a patient with ulcerative colitis who was successfully treated with upadacitinib"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0808-7529","authenticated-orcid":false,"given":"Ryosuke","family":"Murata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiki","family":"Okita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Urayoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Yoshikane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuriko","family":"Uomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Misaki","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhei","family":"Umeda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikio","family":"Kawamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Toiyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hayato","family":"Nakagawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"issue":"3","key":"2304_CR1","doi-asserted-by":"publisher","first-page":"193","DOI":"10.1007\/s00535-007-2143-8","volume":"43","author":"K Hori","year":"2008","unstructured":"Hori K, Ikeuchi H, Nakano H, et al. Gastroduodenitis associated with ulcerative colitis. J Gastroenterol. 2008;43(3):193\u2013201. https:\/\/doi.org\/10.1007\/s00535-007-2143-8.","journal-title":"J Gastroenterol"},{"issue":"4","key":"2304_CR2","doi-asserted-by":"publisher","first-page":"268","DOI":"10.1111\/j.1443-1661.2010.01006.x","volume":"22","author":"T Hisabe","year":"2010","unstructured":"Hisabe T, Matsui T, Miyaoka M, et al. Diagnosis and clinical course of ulcerative gastroduodenal lesion associated with ulcerative colitis: possible relationship with pouchitis. Dig Endosc. 2010;22(4):268\u201374. https:\/\/doi.org\/10.1111\/j.1443-1661.2010.01006.x.","journal-title":"Dig Endosc"},{"issue":"1","key":"2304_CR3","doi-asserted-by":"publisher","first-page":"128","DOI":"10.15403\/jgld-5903","volume":"34","author":"S Cauchi","year":"2025","unstructured":"Cauchi S, Van Venetien F, Sciberras M, et al. Colitis trouble up high: a case of gastroduodenal ulcerative colitis and literature review. J Gastrointestin Liver Dis. 2025;34(1):128\u201332. https:\/\/doi.org\/10.15403\/jgld-5903.","journal-title":"J Gastrointestin Liver Dis"},{"key":"2304_CR4","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1007\/s12328-022-01716-3","volume":"16","author":"K Adachi","year":"2023","unstructured":"Adachi K, Sugiyama T, Yamaguchi Y, et al. A case of ulcerative colitis-related postoperative enteritis treated with granulocyte and monocyte apheresis. Clin J Gastroenterol. 2023;16:43\u20137. https:\/\/doi.org\/10.1007\/s12328-022-01716-3.","journal-title":"Clin J Gastroenterol"},{"issue":"1","key":"2304_CR5","doi-asserted-by":"publisher","first-page":"e415","DOI":"10.1002\/deo2.415","volume":"5","author":"K Kojima","year":"2024","unstructured":"Kojima K, Takada J, Otani K, et al. Duodenitis associated with ulcerative colitis and pouchitis after total colectomy successfully treated with upadacitinib: a case report. DEN Open. 2024;5(1):e415. https:\/\/doi.org\/10.1002\/deo2.415.","journal-title":"DEN Open"},{"issue":"10","key":"2304_CR6","doi-asserted-by":"publisher","first-page":"2199","DOI":"10.11280\/gee.63.2199","volume":"63","author":"M Miyakawa","year":"2021","unstructured":"Miyakawa M, Nasuno M, Kato M, et al. Severe enteritis with uncontrollable massive bleeding after total colectomy for ulcerative colitis: a case report. Gastroenterol Endosc. 2021;63(10):2199\u2013206. https:\/\/doi.org\/10.11280\/gee.63.2199.","journal-title":"Gastroenterol Endosc"},{"issue":"19","key":"2304_CR7","doi-asserted-by":"publisher","first-page":"e15035","DOI":"10.1097\/MD.0000000000015035","volume":"98","author":"M Li","year":"2019","unstructured":"Li M, Liu Y, Cui J, et al. Ulcerative colitis with mucosal lesions in duodenum: two case reports. Med (Baltim). 2019;98(19):e15035. https:\/\/doi.org\/10.1097\/MD.0000000000015035.","journal-title":"Med (Baltim)"},{"key":"2304_CR8","doi-asserted-by":"publisher","first-page":"1396","DOI":"10.1007\/s12328-021-01485-5","volume":"14","author":"F Shimoda","year":"2021","unstructured":"Shimoda F, Kuroha M, Chiba H, et al. Ulcerative colitis-related postoperative enteritis treated with anti-tumor necrosis factor therapy: two case reports and a literature review. Clin J Gastroenterol. 2021;14:1396\u2013403. https:\/\/doi.org\/10.1007\/s12328-021-01485-5.","journal-title":"Clin J Gastroenterol"},{"key":"2304_CR9","doi-asserted-by":"publisher","first-page":"396521","DOI":"10.1155\/2012\/396521","volume":"2012","author":"K Endo","year":"2012","unstructured":"Endo K, Kuroha M, Shiga H, et al. Two cases of diffuse duodenitis associated with ulcerative colitis. Case Rep Gastrointest Med. 2012;2012:396521. https:\/\/doi.org\/10.1155\/2012\/396521.","journal-title":"Case Rep Gastrointest Med"},{"issue":"10","key":"2304_CR10","doi-asserted-by":"publisher","first-page":"1407","DOI":"10.1097\/00000478-200010000-00011","volume":"24","author":"R Valdez","year":"2000","unstructured":"Valdez R, Appelman HD, Bronner MP, et al. Diffuse duodenitis associated with ulcerative colitis. Am J Surg Pathol. 2000;24(10):1407\u201313. https:\/\/doi.org\/10.1097\/00000478-200010000-00011.","journal-title":"Am J Surg Pathol"},{"issue":"4","key":"2304_CR11","doi-asserted-by":"publisher","first-page":"405","DOI":"10.23922\/jarc.2021-031","volume":"5","author":"Y Horio","year":"2021","unstructured":"Horio Y, Uchino M, Hori K, et al. Clinical features and therapeutic outcomes of post-colectomy enteritis with ulcerative colitis. J Anus Rectum Colon. 2021;5(4):405\u201313. https:\/\/doi.org\/10.23922\/jarc.2021-031.","journal-title":"J Anus Rectum Colon"},{"issue":"3","key":"2304_CR12","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1007\/s12328-025-02107-0","volume":"18","author":"K Endo","year":"2025","unstructured":"Endo K, Satoh T, Yoshino Y, et al. A case of relapsed pan-colonic ulcerative colitis accompanied with gastroduodenal lesions immediately after COVID-19. Clin J Gastroenterol. 2025;18(3):399\u2013407. https:\/\/doi.org\/10.1007\/s12328-025-02107-0.","journal-title":"Clin J Gastroenterol"},{"issue":"7","key":"2304_CR13","doi-asserted-by":"publisher","first-page":"929","DOI":"10.2169\/internalmedicine.2047-23","volume":"63","author":"T Hayashi","year":"2024","unstructured":"Hayashi T, Terashima T, Nishitani M, et al. Gastroduodenitis associated with active ulcerative colitis treated with infliximab: different clinical course in the colon and gastroduodenal lesions. Intern Med. 2024;63(7):929\u201335. https:\/\/doi.org\/10.2169\/internalmedicine.2047-23.","journal-title":"Intern Med"},{"issue":"25","key":"2304_CR14","doi-asserted-by":"publisher","first-page":"e42924","DOI":"10.1097\/MD.0000000000042924","volume":"104","author":"Q He","year":"2025","unstructured":"He Q, Wei W, Li J, et al. Ulcerative colitis-associated diffuse enteritis without prior colectomy: a case report. Med (Baltim). 2025;104(25):e42924. https:\/\/doi.org\/10.1097\/MD.0000000000042924.","journal-title":"Med (Baltim)"},{"issue":"2","key":"2304_CR15","doi-asserted-by":"publisher","first-page":"273","DOI":"10.5217\/ir.2018.00122","volume":"17","author":"YS Choi","year":"2019","unstructured":"Choi YS, Kim JK, Kim WJ, et al. Remission of diffuse ulcerative duodenitis in a patient with ulcerative colitis after infliximab therapy: a case study and review of the literature. Intest Res. 2019;17(2):273\u20137. https:\/\/doi.org\/10.5217\/ir.2018.00122.","journal-title":"Intest Res"},{"issue":"2","key":"2304_CR16","doi-asserted-by":"publisher","first-page":"172","DOI":"10.1097\/00004836-200102000-00018","volume":"32","author":"S Terashima","year":"2001","unstructured":"Terashima S, Hoshino Y, Kanzaki N, Kogure M, et al. Ulcerative duodenitis accompanying ulcerative colitis. J Clin Gastroenterol. 2001;32(2):172\u20135. https:\/\/doi.org\/10.1097\/00004836-200102000-00018.","journal-title":"J Clin Gastroenterol"},{"issue":"17","key":"2304_CR17","doi-asserted-by":"publisher","first-page":"3847","DOI":"10.12998\/wjcc.v8.i17.3847","volume":"8","author":"Y Yang","year":"2020","unstructured":"Yang Y, Li CQ, Chen WJ, et al. Gastroduodenitis associated with ulcerative colitis: a case report. World J Clin Cases. 2020;8(17):3847\u201352. https:\/\/doi.org\/10.12998\/wjcc.v8.i17.3847.","journal-title":"World J Clin Cases"},{"issue":"1","key":"2304_CR18","doi-asserted-by":"publisher","first-page":"e70205","DOI":"10.1002\/deo2.70205","volume":"6","author":"S Nakatani","year":"2025","unstructured":"Nakatani S, Yamazaki Y, Higuchi K, et al. Vedolizumab induces remission in two cases of ulcerative colitis with upper gastrointestinal involvement. DEN Open. 2025;6(1):e70205. https:\/\/doi.org\/10.1002\/deo2.70205.","journal-title":"DEN Open"},{"issue":"12","key":"2304_CR19","doi-asserted-by":"publisher","first-page":"2335","DOI":"10.1093\/ibd\/izae004","volume":"30","author":"G D\u2019Haens","year":"2024","unstructured":"D\u2019Haens G, Higgins PDR, Peyrin-Biroulet L, et al. Extended induction and prognostic indicators of response in patients treated with Mirikizumab with moderately to severely active ulcerative colitis in the LUCENT trials. Inflamm Bowel Dis. 2024;30(12):2335\u201346. https:\/\/doi.org\/10.1093\/ibd\/izae004.","journal-title":"Inflamm Bowel Dis"},{"issue":"9","key":"2304_CR20","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1016\/j.cgh.2022.11.029","volume":"21","author":"EV Loftus Jr","year":"2023","unstructured":"Loftus EV Jr, Colombel JF, Takeuchi K, et al. Upadacitinib therapy reduces ulcerative colitis symptoms as early as day 1 of induction treatment. clin gastroenterol hepatol. 2023;21(9):2347\u201358. https:\/\/doi.org\/10.1016\/j.cgh.2022.11.029. e6.","journal-title":"Clin Gastroenterol Hepatol"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02304-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12328-026-02304-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02304-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:22:29Z","timestamp":1779963749000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12328-026-02304-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,9]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["2304"],"URL":"https:\/\/doi.org\/10.1007\/s12328-026-02304-5","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"value":"1865-7257","type":"print"},{"value":"1865-7265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,9]]},"assertion":[{"value":"26 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"9 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"This study was conducted in accordance with the ethical principles of the Declaration of Helsinki. Written informed consent for publication, including the use of clinical data and endoscopic images, was obtained from the patient. Patient confidentiality has been strictly maintained.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The authors declare that they have no conflicts of interest.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}