{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:05:07Z","timestamp":1779966307254,"version":"3.53.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s12328-026-02305-4","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T06:20:05Z","timestamp":1773469205000},"page":"632-638","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Thoracoscopic biopsy should be considered for pulmonary nodules with the halo sign during immunotherapy for hepatocellular carcinoma"],"prefix":"10.1007","volume":"19","author":[{"given":"Yoichi","family":"Asano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satoru","family":"Iwamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Yamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Kaku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunio","family":"Hamanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koki","family":"Moriyoshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin\u2019ichi","family":"Miyamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,14]]},"reference":[{"key":"2305_CR1","doi-asserted-by":"publisher","first-page":"1894","DOI":"10.1056\/NEJMoa1915745","volume":"382","author":"RS Finn","year":"2020","unstructured":"Finn RS, Qin S, Ikeda M, et al. Atezolizumab plus bevacizumab in unresectable hepatocellular carcinoma. N Engl J Med. 2020;382:1894\u2013905.","journal-title":"N Engl J Med"},{"key":"2305_CR2","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1016\/j.jhep.2021.11.030","volume":"76","author":"AL Cheng","year":"2022","unstructured":"Cheng AL, Qin S, Ikeda M, et al. Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma. J Hepatol. 2022;76:862\u201373.","journal-title":"J Hepatol"},{"key":"2305_CR3","doi-asserted-by":"publisher","first-page":"1449","DOI":"10.1016\/j.jtho.2021.05.017","volume":"16","author":"C Pozzessere","year":"2021","unstructured":"Pozzessere C, Lazor R, Jumeau R, et al. Imaging features of pulmonary immune-related adverse events. J Thorac Oncol. 2021;16:1449\u201360.","journal-title":"J Thorac Oncol"},{"key":"2305_CR4","doi-asserted-by":"publisher","first-page":"190058","DOI":"10.1183\/16000617.0058-2019","volume":"28","author":"J Cadranel","year":"2019","unstructured":"Cadranel J, Canellas A, Matton L, et al. Pulmonary complications of immune checkpoint inhibitors. Eur Respir Rev. 2019;28:190058.","journal-title":"Eur Respir Rev"},{"key":"2305_CR5","doi-asserted-by":"publisher","first-page":"305","DOI":"10.3390\/cancers11030305","volume":"11","author":"M Porcu","year":"2019","unstructured":"Porcu M, De Silva P, Solinas C, et al. Immunotherapy-associated pulmonary toxicity. Cancers (Basel). 2019;11:305.","journal-title":"Cancers (Basel)"},{"key":"2305_CR6","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1200\/JCO.2016.68.2005","volume":"35","author":"J Naidoo","year":"2017","unstructured":"Naidoo J, Wang X, Woo KM, et al. Pneumonitis in patients treated with anti\u2013programmed death-1\/programmed death ligand 1 therapy. J Clin Oncol. 2017;35:709\u201317.","journal-title":"J Clin Oncol"},{"key":"2305_CR7","doi-asserted-by":"publisher","first-page":"83","DOI":"10.3892\/etm.2023.11782","volume":"25","author":"Y Wu","year":"2023","unstructured":"Wu Y, Yin Y, Yan X, et al. Late-onset immune checkpoint inhibitor-related pneumonitis. Exp Ther Med. 2023;25:83.","journal-title":"Exp Ther Med"},{"key":"2305_CR8","doi-asserted-by":"publisher","first-page":"e31","DOI":"10.1164\/rccm.201906-1202ST","volume":"200","author":"CR Sears","year":"2019","unstructured":"Sears CR, Peikert T, Possick JD, et al. Knowledge gaps in immune checkpoint inhibitor-related pneumonitis. Am J Respir Crit Care Med. 2019;200:e31\u201343.","journal-title":"Am J Respir Crit Care Med"},{"key":"2305_CR9","doi-asserted-by":"publisher","first-page":"862","DOI":"10.1259\/bjr\/77712845","volume":"78","author":"YR Lee","year":"2005","unstructured":"Lee YR, Choi YW, Lee KJ, et al. CT halo sign: the spectrum of pulmonary diseases. Br J Radiol. 2005;78:862\u20135.","journal-title":"Br J Radiol"},{"key":"2305_CR10","doi-asserted-by":"publisher","first-page":"1714","DOI":"10.1200\/JCO.2017.77.6385","volume":"36","author":"JR Brahmer","year":"2018","unstructured":"Brahmer JR, Lacchetti C, Schneider BJ, et al. Management of immune-related adverse events. J Clin Oncol. 2018;36:1714\u201368.","journal-title":"J Clin Oncol"},{"key":"2305_CR11","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1056\/NEJMc1505197","volume":"373","author":"M Nishino","year":"2015","unstructured":"Nishino M, Sholl LM, Hodi FS, et al. Anti\u2013PD-1\u2013related pneumonitis. N Engl J Med. 2015;373:288\u201390.","journal-title":"N Engl J Med"},{"issue":"24","key":"2305_CR12","doi-asserted-by":"publisher","first-page":"6051","DOI":"10.1158\/1078-0432.CCR-16-1320","volume":"22","author":"M Nishino","year":"2016","unstructured":"Nishino M, Ramaiya NH, Awad MM, et al. PD-1 Inhibitor-Related Pneumonitis in Advanced Cancer Patients: Radiographic Patterns and Clinical Course. Clin Cancer Res. 2016;22(24):6051\u201360.","journal-title":"Clin Cancer Res"},{"issue":"1","key":"2305_CR13","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1186\/s12885-023-10649-0","volume":"23","author":"L Pang","year":"2023","unstructured":"Pang L, Xie M, Ma X, et al. Clinical characteristics and therapeutic effects of checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer. BMC Cancer. 2023;23(1):203.","journal-title":"BMC Cancer"},{"issue":"1","key":"2305_CR14","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.chest.2021.12.659","volume":"162","author":"SV Cherian","year":"2022","unstructured":"Cherian SV, Patel D, Machnicki S, et al. Algorithmic Approach to the Diagnosis of Organizing Pneumonia: A Correlation of Clinical, Radiologic, and Pathologic Features. Chest. 2022;162(1):156\u201378.","journal-title":"Chest"},{"issue":"11","key":"2305_CR15","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1056\/NEJMra2116777","volume":"386","author":"TE King Jr","year":"2022","unstructured":"King TE Jr, Lee JS. Cryptogenic Organizing Pneumonia. N Engl J Med. 2022;386(11):1058\u201369.","journal-title":"N Engl J Med"},{"issue":"12","key":"2305_CR16","doi-asserted-by":"publisher","first-page":"e0871","DOI":"10.1002\/rcr2.871","volume":"9","author":"K Sugino","year":"2021","unstructured":"Sugino K, Ono H, Haraguchi S, et al. Post-coronavirus disease 2019 organizing pneumonia confirmed pathologically by video-assisted thoracoscopic surgery. Respirol Case Rep. 2021;9(12):e0871.","journal-title":"Respirol Case Rep"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02305-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12328-026-02305-4","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02305-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:22:30Z","timestamp":1779963750000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12328-026-02305-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,14]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["2305"],"URL":"https:\/\/doi.org\/10.1007\/s12328-026-02305-4","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"value":"1865-7257","type":"print"},{"value":"1865-7265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,14]]},"assertion":[{"value":"16 December 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"25 February 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"14 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"All the procedures followed were in accordance.with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008(5).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and animal rights"}},{"value":"Informed consent was obtained from the patient described in the study.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Informed consent"}}]}}