{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T11:05:09Z","timestamp":1779966309494,"version":"3.53.1"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T00:00:00Z","timestamp":1775520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Clin J Gastroenterol"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1007\/s12328-026-02323-2","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T08:33:54Z","timestamp":1775550834000},"page":"676-683","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A case of multiple type I endocrine neoplasia with gastrin-producing and glucagon-producing tumors successfully resected 18\u00a0years after insulinoma surgery"],"prefix":"10.1007","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0348-2637","authenticated-orcid":false,"given":"Takashi","family":"Miyata","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taigo","family":"Nagayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hisashi","family":"Nishiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Sannomiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akifumi","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daisuke","family":"Kaida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuto","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichi","family":"Okamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideto","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Takamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"2323_CR1","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1507\/endocrj.K06-104","volume":"54","author":"A Nakagawa","year":"2007","unstructured":"Nakagawa A, Ueno K, Ito M, et al. Insulin responses to selective arterial calcium infusion under hyperinsulinemic euglycemic glucose clamps: case studies in adult nesidioblastosis and childhood insulinoma. Endocr J. 2007;54:27\u201333.","journal-title":"Endocr J"},{"key":"2323_CR2","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1297\/cpe.26.25","volume":"26","author":"M Itoh","year":"2017","unstructured":"Itoh M, Saikawa Y. A novel MEN1 mutation in a Japanese adolescent with multiple endocrine neoplasia type 1. Clin Pediatr Endocrinol. 2017;26:25\u20138.","journal-title":"Clin Pediatr Endocrinol"},{"issue":"5","key":"2323_CR3","doi-asserted-by":"publisher","DOI":"10.1111\/jne.13306","volume":"35","author":"F Panzuto","year":"2023","unstructured":"Panzuto F, Ramage J, Pritchard DM, et al. European Neuroendocrine Tumor Society (ENETS) 2023 guidance paper for gastroduodenal neuroendocrine tumours (NETs) G1\u2013G3. J Neuroendocrinol. 2023;35(5):e13306. https:\/\/doi.org\/10.1111\/jne.13306.","journal-title":"J Neuroendocrinol"},{"key":"2323_CR4","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1210\/endrev\/bnaa031","volume":"42","author":"ML Brandi","year":"2021","unstructured":"Brandi ML, Agarwal SK, Perrier ND, et al. Multiple endocrine neoplasia type 1 latest insights. Endocr Rev. 2021;42:133\u201370.","journal-title":"Endocr Rev"},{"key":"2323_CR5","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1111\/j.1365-2265.2011.04227.x","volume":"76","author":"A Sakurai","year":"2012","unstructured":"Sakurai A, Suzuki S, Kosugi S, et al. Multiple endocrine neoplasia type 1 in Japan: establishment and analysis of a multicentre database. Clin Endocrinol. 2012;76:533\u20139.","journal-title":"Clin Endocrinol"},{"key":"2323_CR6","doi-asserted-by":"publisher","first-page":"680","DOI":"10.1097\/MPA.0b013e3181d36341","volume":"39","author":"G Zhou","year":"2010","unstructured":"Zhou G, Wei Y, Chen X, et al. Multiple endocrine neoplasia type 1 simultaneous with various types of enteropancreatic endocrine tumors: one case report: lessons learned. Pancreas. 2010;39:680\u20133.","journal-title":"Pancreas"},{"key":"2323_CR7","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1007\/s11102-011-0334-z","volume":"15","author":"M Varsavsky","year":"2012","unstructured":"Varsavsky M, Reyes-Garc\u00eda R, Garc\u00eda GA, et al. An unusual association of neuroendocrine tumors in MEN 1A. Pituitary. 2012;15:393\u20137.","journal-title":"Pituitary"},{"key":"2323_CR8","doi-asserted-by":"publisher","first-page":"953","DOI":"10.3346\/jkms.2010.25.6.953","volume":"25","author":"SR Lee","year":"2010","unstructured":"Lee SR, Choi MC, Ahn KJ. A case of multiple endocrine neoplasia type 1 with primary liver gastrinoma. J Korean Med Sci. 2010;25:953\u20136.","journal-title":"J Korean Med Sci"},{"key":"2323_CR9","doi-asserted-by":"publisher","first-page":"224","DOI":"10.12659\/AJCR.883383","volume":"13","author":"J Li","year":"2012","unstructured":"Li J, Zeng L, Yang Y, et al. Multiple endocrine neoplasia type 1 presenting multiple lipomas and hypoglycemia onset. Am J Case Rep. 2012;13:224\u20139.","journal-title":"Am J Case Rep"},{"key":"2323_CR10","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1086\/301729","volume":"62","author":"JH Bassett","year":"1998","unstructured":"Bassett JH, Forbes SA, Pannett AA, et al. Characterization of mutations in patients with multiple endocrine neoplasia type 1. Am J Hum Genet. 1998;62:232\u201344.","journal-title":"Am J Hum Genet"},{"key":"2323_CR11","doi-asserted-by":"publisher","first-page":"173","DOI":"10.1159\/000098009","volume":"84","author":"RT Jensen","year":"2006","unstructured":"Jensen RT, Niederle B, Mitry E, et al. Gastrinoma (duodenal and pancreatic). Neuroendocrinology. 2006;84:173\u201382.","journal-title":"Neuroendocrinology"},{"key":"2323_CR12","doi-asserted-by":"publisher","first-page":"1469","DOI":"10.1053\/j.gastro.2008.05.047","volume":"135","author":"DC Metz","year":"2008","unstructured":"Metz DC, Jensen RT. Gastrointestinal neuroendocrine tumors: pancreatic endocrine tumors. Gastroenterology. 2008;135:1469\u201392.","journal-title":"Gastroenterology"},{"key":"2323_CR13","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.gie.2014.09.037","volume":"81","author":"SJ van Asselt","year":"2015","unstructured":"van Asselt SJ, Brouwers AH, van Dullemen HM, et al. EUS is superior for detection of pancreatic lesions compared with standard imaging in patients with multiple endocrine neoplasia type l. Gastrointest Endosc. 2015;81:159\u201367.","journal-title":"Gastrointest Endosc"},{"key":"2323_CR14","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1007\/s00535-009-0194-8","volume":"45","author":"T Ito","year":"2010","unstructured":"Ito T, Sasano H, Tanaka M, et al. Epidemiological study of gastroenteropancreatic neuroendocrine tumors in Japan. J Gastroenterol. 2010;45:234\u201343.","journal-title":"J Gastroenterol"},{"key":"2323_CR15","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1159\/000335591","volume":"95","author":"RT Jensen","year":"2012","unstructured":"Jensen RT, Cadiot G, Brandi ML, et al. ENETS consensus guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes. Neuroendocrinology. 2012;95:98.","journal-title":"Neuroendocrinology"},{"key":"2323_CR16","doi-asserted-by":"publisher","first-page":"1378","DOI":"10.1097\/00000478-199611000-00009","volume":"20","author":"MF Le Bodic","year":"1996","unstructured":"Le Bodic MF, Heymann MF, Lecomte M, et al. Immunohistochemical study of 100 pancreatic tumors in 28 patients with multiple endocrine neoplasia, type I. Am J Surg Pathol. 1996;20:1378\u201384.","journal-title":"Am J Surg Pathol"}],"container-title":["Clinical Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02323-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12328-026-02323-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12328-026-02323-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,28]],"date-time":"2026-05-28T10:22:50Z","timestamp":1779963770000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12328-026-02323-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,7]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["2323"],"URL":"https:\/\/doi.org\/10.1007\/s12328-026-02323-2","relation":{},"ISSN":["1865-7257","1865-7265"],"issn-type":[{"value":"1865-7257","type":"print"},{"value":"1865-7265","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,7]]},"assertion":[{"value":"26 September 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 April 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors report no potential conflicts of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Informed consent was obtained from patient, and the study was performed in accordance with the principles of the Declaration of Helsinki. Ethical approval was deemed unnecessary for this work.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"The patient gave written informed consent for the publication of the case details and associated images. A copy of the signed consent is accessible to the Editor-in-Chief of this journal for verification.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}}]}}