{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:16:39Z","timestamp":1788869799036,"version":"build-2803163510"},"reference-count":20,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,6,1]],"date-time":"2019-06-01T00:00:00Z","timestamp":1559347200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T00:00:00Z","timestamp":1545264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.elsevierhealth.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Nuclear Cardiology"],"published-print":{"date-parts":[[2019,6]]},"DOI":"10.1007\/s12350-018-01548-0","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T11:40:26Z","timestamp":1545306026000},"page":"1007-1014","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Aminophylline shortage and current recommendations for reversal of vasodilator stress: An ASNC information statement endorsed by SCMR"],"prefix":"10.1016","volume":"26","author":[{"given":"Aiden","family":"Abidov","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasken","family":"Dilsizian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami","family":"Doukky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Lane","family":"Duvall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Dyke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fadi G.","family":"Hage","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena J.","family":"Henzlova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nils P.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald G.","family":"Schwartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory S.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Einstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1007\/s12350-018-01548-0_bib1","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1007\/s12350-015-0387-x","article-title":"ASNC imaging guidelines for SPECT nuclear cardiology procedures: Stress, protocols, and tracers","volume":"23","author":"Henzlova","year":"2016","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib2","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1007\/s12350-016-0553-9","article-title":"Effect of aminophylline administration on the diagnostic yield of vasodilator myocardial perfusion imaging","volume":"24","author":"Daya","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib3","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1007\/s12350-015-0141-4","article-title":"Serious and potentially life threatening complications of cardiac stress testing: Physiological mechanisms and management strategies","volume":"22","author":"Dilsizian","year":"2015","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib4","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1007\/s12350-016-0448-9","article-title":"Safety of vasodilator stress myocardial perfusion imaging in patients with elevated cardiac biomarkers","volume":"24","author":"Rai","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib5","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12350-012-9654-2","article-title":"The safety and tolerability of regadenoson in patients with end-stage renal disease: The first prospective evaluation","volume":"20","author":"Doukky","year":"2013","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib6","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1007\/s12350-014-0036-9","article-title":"Severe chronic kidney disease as a predictor of benefit from aminophylline administration in patients undergoing regadenoson stress myocardial perfusion imaging: A substudy of the ASSUAGE and ASSUAGE-CKD trials","volume":"22","author":"Rangel","year":"2015","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib7","first-page":"664","article-title":"Technetium-99m-tetrofosmin to assess myocardial blood flow: Experimental validation in an intact canine model of ischemia","volume":"35","author":"Sinusas","year":"1994","journal-title":"J Nucl Med"},{"key":"10.1007\/s12350-018-01548-0_bib8","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0002-8703(05)80321-7","article-title":"Relationship between regional myocardial blood flow and the distribution of 99mTc-sestamibi in the presence of total coronary artery occlusion","volume":"119","author":"Mousa","year":"1990","journal-title":"Am Heart J"},{"key":"10.1007\/s12350-018-01548-0_bib9","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1161\/01.CIR.96.7.2332","article-title":"Myocardial 99mTc-tetrofosmin uptake during adenosine-induced vasodilatation with either a critical or mild coronary stenosis: Comparison with 201Tl and regional myocardial blood flow","volume":"96","author":"Glover","year":"1997","journal-title":"Circulation"},{"key":"10.1007\/s12350-018-01548-0_bib10","series-title":"Clinical nuclear cardiology","first-page":"3","article-title":"Overview of tracer kinetics and cellular mechanisms of uptake","author":"Watson","year":"2010"},{"key":"10.1007\/s12350-018-01548-0_bib11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.brainres.2009.08.050","article-title":"Adenosine A2A receptor deficiency reduces striatal glutamate outflow and attenuates brain injury induced by transient focal cerebral ischemia in mice","volume":"1297","author":"Gui","year":"2009","journal-title":"Brain Res"},{"key":"10.1007\/s12350-018-01548-0_bib12","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1007\/s12350-016-0484-5","article-title":"Intravenous caffeine: An alternative to aminophylline to reverse adverse effects during regadenoson myocardial perfusion imaging","volume":"24","author":"Jolly","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib13","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1007\/s10554-012-0166-6","article-title":"Attenuation of the side effect profile of regadenoson: A randomized double-blind placebo-controlled study with aminophylline in patients undergoing myocardial perfusion imaging and have severe chronic kidney disease\u2014The ASSUAGE-CKD trial","volume":"29","author":"Doukky","year":"2013","journal-title":"Int J Cardiovasc Imaging"},{"key":"10.1007\/s12350-018-01548-0_bib14","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1007\/s12350-012-9533-x","article-title":"Attenuation of the side effect profile of regadenoson: A randomized double-blinded placebo-controlled study with aminophylline in patients undergoing myocardial perfusion imaging. \u201cThe ASSUAGE trial\u201d","volume":"19","author":"Doukky","year":"2012","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib15","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1007\/s12350-016-0506-3","article-title":"Impact of a regimented aminophylline administration protocol on the burden of regadenoson-induced ischemia detected by SPECT myocardial perfusion imaging","volume":"24","author":"Fughhi","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib16","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1007\/s12350-011-9445-1","article-title":"Dipyridamole reversal using theophylline during aminophylline shortage","volume":"18","author":"Johnson","year":"2011","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib17","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1007\/s12350-016-0452-0","article-title":"Aminophylline and caffeine for reversal of adverse symptoms associated with regadenoson SPECT MPI","volume":"24","author":"Doran","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib18","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1007\/s12350-014-9926-0","article-title":"Buccal caffeine for the routine reversal of Persantine","volume":"21","author":"Matangi","year":"2014","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib19","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1007\/s12350-016-0407-5","article-title":"Arrhythmias in vasodilator stress testing","volume":"24","author":"Subbiah","year":"2017","journal-title":"J Nucl Cardiol"},{"key":"10.1007\/s12350-018-01548-0_bib20","article-title":"Prognostic significance of ischemic electrocardiographic changes with regadenoson stress myocardial perfusion imaging","author":"Doukky","year":"2018","journal-title":"J Nucl Cardiol"}],"container-title":["Journal of Nuclear Cardiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12350-018-01548-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12350-018-01548-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071358123062074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1071358123062074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12350-018-01548-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T06:05:01Z","timestamp":1761026701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1071358123062074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,6]]}},"alternative-id":["S1071358123062074"],"URL":"https:\/\/doi.org\/10.1007\/s12350-018-01548-0","relation":{},"ISSN":["1071-3581"],"issn-type":[{"value":"1071-3581","type":"print"}],"subject":[],"published":{"date-parts":[[2019,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aminophylline shortage and current recommendations for reversal of vasodilator stress: An ASNC information statement endorsed by SCMR","name":"articletitle","label":"Article Title"},{"value":"Journal of Nuclear Cardiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s12350-018-01548-0","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2019 THE AUTHORS. Published by ELSEVIER INC. on behalf of American Society of Nuclear Cardiology. Published by Mosby, Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}