{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T07:16:45Z","timestamp":1789197405620,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neth Heart J"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec>\n<jats:title>Aims<\/jats:title>\n<jats:p>Spinal cord stimulation (SCS) is a\u00a0treatment for patients with refractory angina pectoris (RAP) who remain symptomatic despite optimal medical therapy and without revascularisation options. Previous studies have shown that SCS improves the quality of life in this patient group and reduces the severity of the angina pectoris. The aim of this prospective, single-arm observational study is to show this effect in a\u00a0single-centre cohort using a\u00a0multidisciplinary team approach to the selection process, with a\u00a0follow-up period of 1\u00a0year.<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Methods and results<\/jats:title>\n<jats:p>Between July 2010 and March 2017, 87\u00a0patients with RAP referred to our centre received SCS. The Seattle Angina Questionnaire (SAQ) and RAND 36-Item Health Survey (RAND-36) were completed at baseline, prior to implantation, and 1\u00a0year post-implantation. After 1\u00a0year of follow-up there was a\u00a0statistically significant decrease in the frequency of angina pectoris attacks from more than 4\u00a0times a\u00a0day to 1\u20132\u00a0times a\u00a0week (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001). The SAQ showed statistically significant improvement in four of the five dimensions: physical limitation (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), angina frequency (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), angina stability (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001) and quality of life (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001). The RAND-36 showed statistically significant improvement in all nine dimensions: physical functioning (<jats:italic>p<\/jats:italic>\u202f=\u20090.001), role\/physical (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), social functioning (<jats:italic>p<\/jats:italic>\u202f=\u20090.03), role\/emotional (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.05), bodily pain (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), general health (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), vitality (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001), mental health (<jats:italic>p<\/jats:italic>\u202f=\u20090.02) and health change (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.001).<\/jats:p>\n<\/jats:sec><jats:sec>\n<jats:title>Conclusion<\/jats:title>\n<jats:p>This study showed a\u00a0significant improvement in quality of life and reduction of angina pectoris severity after 1\u00a0year of follow-up in patients treated with SCS for RAP.<\/jats:p>\n<\/jats:sec>","DOI":"10.1007\/s12471-020-01422-0","type":"journal-article","created":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T14:19:16Z","timestamp":1589897956000},"page":"478-484","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Improvement in quality of life and angina pectoris: 1-year follow-up of patients with refractory angina pectoris and spinal cord stimulation"],"prefix":"10.1007","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6693-7355","authenticated-orcid":false,"given":"F. 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