{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:25:45Z","timestamp":1787239545262,"version":"build-2736575974"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"7-8","license":[{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T00:00:00Z","timestamp":1614988800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neth Heart J"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Circulatory extracorporeal life support (ECLS) has been performed at the University Medical Centre Utrecht for 12\u00a0years. During this time, case mix, indications, ECLS set-ups and outcomes seem to have substantially changed. We set out to describe these characteristics and their evolution over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients receiving circulatory ECLS between 2007 and 2018 were retrospectively identified and divided into six groups according to a\u00a02-year period of time corresponding to the date of ECLS initiation. General characteristics plus data pertaining to comorbidities, indications and technical details of ECLS commencement as well as in-hospital, 30-day, 1\u2011year and overall mortality were collected. Temporal trends in these characteristics were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A\u00a0total of 347 circulatory ECLS runs were performed in 289\u00a0patients. The number of patients and ECLS runs increased from 8\u00a0till a\u00a0maximum of 40\u00a0runs a\u00a0year. The distribution of circulatory ECLS indications shifted from predominantly postcardiotomy to a\u00a0wider set of indications. The proportion of peripheral insertions with or without application of left ventricular unloading techniques substantially increased, while in-hospital, 30-day, 1\u2011year and overall mortality decreased over time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Circulatory ECLS was increasingly applied at the University Medical Centre Utrecht. Over time, indications as well as treatment goals broadened, and cannulation techniques shifted from central to mainly peripheral approaches. Meanwhile, weaning success increased and mortality rates diminished.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12471-021-01552-z","type":"journal-article","created":{"date-parts":[[2021,3,6]],"date-time":"2021-03-06T06:04:28Z","timestamp":1615010668000},"page":"394-401","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Twelve years of circulatory extracorporeal life support at the University Medical Centre Utrecht"],"prefix":"10.1007","volume":"29","author":[{"given":"C. L.","family":"Meuwese","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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The other authors have no conflict of interest to report. C.L.\u00a0Meuwese, J.A.\u00a0Hermens, M.\u00a0de Haan, S.A.\u00a0Braithwaite, F.\u00a0Ramjankhan, M.P.\u00a0Buijsrogge, N.\u00a0de Jonge, J.H.\u00a0Kirkels, M.\u00a0de Jong, W.\u00a0Pasma, J.L.P.\u00a0Vromen-Wijsman, A.O.\u00a0Kraaijeveld, E.E.\u00a0de Waal, E.\u00a0Torn, M.\u00a0Platenkamp, J.J.\u00a0van der Heijden, O.L.\u00a0Cremer and D.\u00a0van Dijk declare that they have no competing interests.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}