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These patients are easily misdiagnosed, and their prognosis is poor, even after surgical treatment. This study aimed to analyse potential factors that can improve the prognosis of BD patients with aortic regurgitation and\/or aortic involvement.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Methods<\/jats:title>\n                <jats:p>Twenty-two patients with diagnosed or suspected BD as well as aortic regurgitation and\/or aortic involvement in our hospital from 2012 through 2017 were collected in this study. Their clinical characteristics were listed, and the diagnosis of BD was evaluated by two different criteria sets. The influences of surgical treatment and immunosuppressive therapy (IST) on their prognosis were also explored.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Results<\/jats:title>\n                <jats:p>The diagnostic positive rate of the International Criteria for Beh\u00e7et\u2019s Disease was higher than that of the International Study Group criteria (kappa value 0.31, <jats:italic>p<\/jats:italic>\u202f&lt;\u20090.05), indicating that the diagnostic consistency between the criteria sets was poor. There was no significant difference in survival between patients who had undergone \u2264\u202f1 operation and those with \u2265\u202f2 operations. Aortic valve replacement alone or in combination with aortic root replacement had no significant effect on the incidence of reoperation or death, but IST did significantly reduce this incidence (<jats:italic>p<\/jats:italic>\u202f&lt;\u20090.05). However, there was no significant difference in the occurrence of reoperation or death between preoperative and postoperative IST versus postoperative IST only.<\/jats:p>\n              <\/jats:sec><jats:sec>\n                <jats:title>Conclusion<\/jats:title>\n                <jats:p>IST significantly improved the prognosis of BD patients with aortic regurgitation and\/or aortic involvement.<\/jats:p>\n              <\/jats:sec>","DOI":"10.1007\/s12471-021-01567-6","type":"journal-article","created":{"date-parts":[[2021,4,20]],"date-time":"2021-04-20T06:03:24Z","timestamp":1618898604000},"page":"172-180","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Prognostic analysis of Beh\u00e7et\u2019s disease with aortic regurgitation or involvement"],"prefix":"10.1007","volume":"30","author":[{"given":"X.","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Q.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,4,20]]},"reference":[{"key":"1567_CR1","doi-asserted-by":"publisher","first-page":"63","DOI":"10.5830\/CVJA-2014-003","volume":"25","author":"Z Ulusan","year":"2014","unstructured":"Ulusan\u00a0Z, Karadag\u00a0AS, Tasar\u00a0M, Kalender\u00a0M, Darcin\u00a0OT. 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