{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T14:42:20Z","timestamp":1787582540870,"version":"build-2736575974"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","issue":"9","license":[{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T00:00:00Z","timestamp":1785283200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neth Heart J"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The optimal valve substitute for young and middle-aged patients with severe symptomatic aortic valve disease remains a\u00a0subject of debate. In this patient group, prosthetic valves are associated with reduced survival, impaired hemodynamics, and lifelong risk of valve-related complications. The Ross procedure has re-emerged as the most optimal valve substitute following surgical refinements and improved perioperative care. The current study describes the feasibility in terms of safety and early outcomes of a\u00a0newly initiated Ross program using the patient-tailored total root technique.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>All patients who underwent the Ross procedure at the Radboud University Medical Center between April 2024 and December 2025 were included. Baseline characteristics, operative details, and postoperative outcomes were extracted from the electronic medical record.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A\u00a0total of 32\u00a0patients were included, with a\u00a0median age of 39\u00a0years; 65% were male, and 94% had a\u00a0bicuspid aortic valve. The predominant pathology was pure stenosis in 63%. All procedures were elective except one. There was no operative or 30-day mortality. Complications included one conversion to a\u00a0Bentall procedure for leaflet retraction and one urgent percutaneous coronary intervention, probably due to right coronary button kinking. No patient had more than mild aortic regurgitation at discharge.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The Ross procedure in young and middle-aged adults was associated with favorable short-term outcomes in this initial cohort. These results support the feasibility and safety of the Ross procedure when performed in a\u00a0dedicated expert center. Ongoing follow-up will be essential to assess medium- and long-term durability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1007\/s12471-026-02062-6","type":"journal-article","created":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T10:38:18Z","timestamp":1785321498000},"page":"306-311","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The feasibility of the introduction of the Ross program in adults: early safety and quality outcomes in a\u00a0single center"],"prefix":"10.1007","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-3206-5202","authenticated-orcid":false,"given":"Nabil","family":"Saouti","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthonie L.","family":"Duijnhouwer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim J.","family":"Ten Cate","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arie P. J.","family":"van Dijk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin H.","family":"Heijmen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,7,29]]},"reference":[{"key":"2062_CR1","doi-asserted-by":"crossref","unstructured":"Praz F, Borger MA, Lanz J, et\u00a0al. 2025 ESC\/EACTS Guidelines for the management of valvular heart disease. Eur Heart J. 2025;46:4635\u2013736.","DOI":"10.1093\/ejcts\/ezaf393"},{"key":"2062_CR2","doi-asserted-by":"crossref","unstructured":"Bowdish ME, Mehaffey JH, Chang SC, et\u00a0al. Bioprosthetic vs Mechanical Aortic Valve Replacement in Patients 40 to 75 Years of Age. J\u00a0Am Coll Cardiol. 2025;85:1289\u201398.","DOI":"10.1016\/j.jacc.2025.01.013"},{"key":"2062_CR3","doi-asserted-by":"crossref","unstructured":"El-Hamamsy I, Toyoda N, Itagaki S, et\u00a0al. 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T.J.\u00a0Ten Cate serves as an editor for The Netherlands Heart Journal.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}