{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T06:24:33Z","timestamp":1762323873173},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2015,10,11]],"date-time":"2015-10-11T00:00:00Z","timestamp":1444521600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Pediatr"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1007\/s12519-015-0042-2","type":"journal-article","created":{"date-parts":[[2015,10,10]],"date-time":"2015-10-10T03:21:17Z","timestamp":1444447277000},"page":"331-337","update-policy":"http:\/\/dx.doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Inflammatory bowel disease in Turkish children"],"prefix":"10.1007","volume":"11","author":[{"given":"Murat","family":"Cakir","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"Unal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gonul","family":"Dinler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masallah","family":"Baran","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan Ali","family":"Yuksekkaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gokhan","family":"Tumgor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erhun","family":"Kasirga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayhan Gazi","family":"Kalayci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sema","family":"Aydogdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2015,10,11]]},"reference":[{"key":"42_CR1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/gast.2001.22122","volume":"120","author":"F Shanahan","year":"2001","unstructured":"Shanahan F. Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeutics. Gastroenterology 2001;120:622\u2013635.","journal-title":"Gastroenterology"},{"key":"42_CR2","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/01.MIB.0000166932.66853.fd","volume":"11","author":"E Hait","year":"2005","unstructured":"Hait E, Bousvaros A, Grand R. Pediatric inflammatory bowel disease: what children can teach adults. Inflamm Bowel Dis 2005;11:519\u2013527.","journal-title":"Inflamm Bowel Dis"},{"key":"42_CR3","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1136\/archdischild-2012-302018","volume":"97","author":"P Henderson","year":"2012","unstructured":"Henderson P, Wilson DC. The rising incidence of paediatriconset infl ammatory bowel disease. Arch Dis Child 2012;97:585\u2013586.","journal-title":"Arch Dis Child"},{"key":"42_CR4","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1002\/ibd.20470","volume":"14","author":"M Castro","year":"2008","unstructured":"Castro M, Papadatou B, Baldassare M, Balli F, Barabino A, Barbera C, et al. Inflammatory bowel disease in children and adolescents in Italy: data from the pediatric national IBD register (1996\u20132003). Infl amm Bowel Dis 2008;14:1246\u20131252.","journal-title":"Infl amm Bowel Dis"},{"key":"42_CR5","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1067\/S0022-3476(03)00444-X","volume":"143","author":"S Kugathasan","year":"2003","unstructured":"Kugathasan S, Judd RH, Hoffmann RG, Heikenen J, Telega G, Khan F, et al. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J Pediatr 2003;143:525\u2013531.","journal-title":"J Pediatr"},{"key":"42_CR6","doi-asserted-by":"crossref","first-page":"323","DOI":"10.4103\/1319-3767.84487","volume":"17","author":"WA Al-Qabandi","year":"2011","unstructured":"Al-Qabandi WA, Buhamrah EK, Hamadi KA, Al-Osaimi SA, Al-Ruwayeh AA, Madda J. Infl ammatory bowel disease in children, an evolving problem in Kuwait. Saudi Saudi J Gastroenterol 2011;17:323\u2013327.","journal-title":"Saudi Saudi J Gastroenterol"},{"key":"42_CR7","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/S0140-6736(00)04309-9","volume":"357","author":"A Sawczenko","year":"2001","unstructured":"Sawczenko A, Sandhu BK, Logan RF, Jenkins H, Taylor CJ, Mian S, et al. Prospective survey of childhood inflammatory bowel disease in the British Isles. Lancet 2001;357:1093\u20131094.","journal-title":"Lancet"},{"key":"42_CR8","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1136\/archdischild-2011-300651","volume":"97","author":"B Hope","year":"2012","unstructured":"Hope B, Shahdadpuri R, Dunne C, Broderick AM, Grant T, Hamzawi M, et al. Rapid rise in incidence of Irish paediatric infl ammatory bowel disease. Arch Dis Child 2012;97:590\u2013594.","journal-title":"Arch Dis Child"},{"key":"42_CR9","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1007\/s10620-009-0963-5","volume":"55","author":"BJ Kim","year":"2010","unstructured":"Kim BJ, Song SM, Kim KM, Lee YJ, Rhee KW, Jang JY, et al. Characteristics and trends in the incidence of inflammatory bowel disease in Korean children: a single-center experience. Dig Dis Sci 2010;55:1989\u20131995.","journal-title":"Dig Dis Sci"},{"key":"42_CR10","first-page":"423","volume":"33","author":"M A El Mouzan","year":"2012","unstructured":"El Mouzan MI, Al Mofarreh MA, Assiri AM, Hamid YH, Al Jebreen AM, Azzam NA. Presenting features of childhoodonset infl ammatory bowel disease in the central region of Saudi Arabia. Saudi Med J 2012;33:423\u2013428.","journal-title":"Saudi Med J"},{"key":"42_CR11","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1097\/MPG.0b013e3182662233","volume":"55","author":"D Turner","year":"2012","unstructured":"Turner D, Levine A, Escher JC, Griffiths AM, Russell RK, Dignass A, et al. Management of pediatric ulcerative colitis: joint ECCO and ESPGHAN evidence-based consensus guidelines. J Pediatr Gastroenterol Nutr 2012;55:340\u2013361.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR12","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1002\/ibd.21493","volume":"17","author":"A Levine","year":"2011","unstructured":"Levine A, Griffiths A, Markowitz J, Wilson DC, Turner D, Russell RK, et al. Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classifi cation. Infl amm Bowel Dis 2011;17:1314\u20131321.","journal-title":"Infl amm Bowel Dis"},{"key":"42_CR13","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1002\/ibd.21349","volume":"17","author":"EI Benchimol","year":"2011","unstructured":"Benchimol EI, Fortinsky KJ, Gozdyra P, Van den Heuvel M, Van Limbergen J, Griffiths AM. Epidemiology of pediatric infl ammatory bowel disease: a systematic review of international trends. Infl amm Bowel Dis 2011;17:423\u2013439.","journal-title":"Infl amm Bowel Dis"},{"key":"42_CR14","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1177\/153537020422901108","volume":"229","author":"MT Cantorna","year":"2004","unstructured":"Cantorna MT, Mahon BD. Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence. Exp Biol Med (Maywood) 2004;229:1136\u20131142.","journal-title":"Exp Biol Med (Maywood)"},{"key":"42_CR15","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1097\/MPG.0000000000000274","volume":"58","author":"G Karag\u00fczel","year":"2014","unstructured":"Karag\u00fczel G, Dilber B, \u00c7an G, \u00d6kten A, Deger O, Holick MF. Seasonal vitamin D status of healthy schoolchildren and predictors of low vitamin D status. J Pediatr Gastroenterol Nutr 2014;58:654\u2013660.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR16","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1136\/gut.30.5.618","volume":"30","author":"JR Barton","year":"1989","unstructured":"Barton JR, Gillon S, Ferguson A. Incidence of inflammatory bowel disease in Scottish children between 1968 and 1983; marginal fall in ulcerative colitis, three-fold rise in Crohn\u2019s disease. Gut 1989;30:618\u2013622.","journal-title":"Gut"},{"key":"42_CR17","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1136\/adc.74.5.460","volume":"74","author":"M Cosgrove","year":"1996","unstructured":"Cosgrove M, Al-Atia RF, Jenkins HR. The epidemiology of paediatric inflammatory bowel disease. Arch Dis Child 1996;74:460\u2013461.","journal-title":"Arch Dis Child"},{"key":"42_CR18","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1097\/00005176-200003000-00009","volume":"30","author":"E Lindberg","year":"2000","unstructured":"Lindberg E, Lindquist B, Holmquist L, Hildebrand H. Inflammatory bowel disease in children and adolescents in Sweden, 1984\u20131995. J Pediatr Gastroenterol Nutr 2000;30:259\u2013264.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR19","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1093\/oxfordjournals.aje.a009735","volume":"149","author":"CN Bernstein","year":"1999","unstructured":"Bernstein CN, Blanchard JF, Rawsthorne P, Wajda A. Epidemiology of Crohn\u2019s disease and ulcerative colitis in a central Canadian province: a population-based study. Am J Epidemiol 1999;149:916\u2013924.","journal-title":"Am J Epidemiol"},{"key":"42_CR20","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1097\/MPG.0b013e31826d9987","volume":"56","author":"M El Mouzan","year":"2013","unstructured":"El Mouzan M, Al-Mofarreh M, Assiri A, Hamid Y, Saeed A. Consanguinity and inflammatory bowel diseases: is there a relation? J Pediatr Gastroenterol Nutr 2013;56:182\u2013185.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR21","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1097\/00005176-200311000-00020","volume":"37","author":"TA Weinstein","year":"2003","unstructured":"Weinstein TA, Levine M, Pettei MJ, Gold DM, Kessler BH, Levine JJ. Age and family history at presentation of pediatric inflammatory bowel disease. J Pediatr Gastroenterol Nutr 2003;37:609\u2013613.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR22","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1002\/ibd.21585","volume":"17","author":"MD Long","year":"2011","unstructured":"Long MD, Crandall WV, Leibowitz IH, Duffy L, del Rosario F, Kim SC, et al. Prevalence and epidemiology of overweight and obesity in children with inflammatory bowel disease. Inflamm Bowel Dis 2011;17:2162\u20132168.","journal-title":"Inflamm Bowel Dis"},{"key":"42_CR23","doi-asserted-by":"crossref","first-page":"3488","DOI":"10.1007\/s10620-010-1178-5","volume":"55","author":"N Uslu","year":"2010","unstructured":"Uslu N, Y\u00fcce A, Demir H, Saltik-Temizel IN, Usta Y, Yilmaz E, et al. The association of inflammatory bowel disease and Mediterranean fever gene (MEFV) mutations in Turkish children. Dig Dis Sci 2010;55:3488\u20133494.","journal-title":"Dig Dis Sci"},{"key":"42_CR24","doi-asserted-by":"crossref","first-page":"e23","DOI":"10.1097\/MCG.0b013e3182597992","volume":"47","author":"F Akyuz","year":"2013","unstructured":"Akyuz F, Besisik F, Ustek D, Ekmek\u00e7i C, Uyar A, Pinarbasi B, et al. Association of the MEFV gene variations with inflammatory bowel disease in Turkey. J Clin Gastroenterol 2013;47:e23\u2013e27.","journal-title":"J Clin Gastroenterol"},{"key":"42_CR25","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1007\/s00431-007-0508-x","volume":"167","author":"S Sari","year":"2008","unstructured":"Sari S, Egritas O, Dalgic B. The familial Mediterranean fever (MEFV) gene may be a modifier factor of inflammatory bowel disease in infancy. Eur J Pediatr 2008;167:391\u2013393.","journal-title":"Eur J Pediatr"},{"key":"42_CR26","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1097\/MPG.0b013e31827dd763","volume":"56","author":"OF Beser","year":"2013","unstructured":"Beser OF, Kasap\u00e7opur O, Cokugras FC, Kutlu T, Arsoy N, Erkan T. Association of inflammatory bowel disease with familial Mediterranean fever in Turkish children. J Pediatr Gastroenterol Nutr 2013;56:498\u2013502.","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"42_CR27","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1136\/archdischild-2011-300633","volume":"96","author":"MD Kappelman","year":"2011","unstructured":"Kappelman MD, Galanko JA, Porter CQ, Sandler RS. Association of paediatric infl ammatory bowel disease with other immune-mediated diseases. Arch Dis Child 2011;96:1042\u20131046.","journal-title":"Arch Dis Child"},{"key":"42_CR28","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.jpeds.2004.08.043","volume":"146","author":"MB Heyman","year":"2005","unstructured":"Heyman MB, Kirschner BS, Gold BD, Ferry G, Baldassano R, Cohen SA, et al. Children with early-onset infl ammatory bowel disease (IBD): analysis of a pediatric IBD consortium registry. J Pediatr 2005;146:35\u201340.","journal-title":"J Pediatr"},{"key":"42_CR29","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1542\/peds.2006-1865","volume":"119","author":"DR Mack","year":"2007","unstructured":"Mack DR, Langton C, Markowitz J, LeLeiko N, Griffiths A, Bousvaros A, et al. Laboratory values for children with newly diagnosed inflammatory bowel disease. Pediatrics 2007;119:1113\u20131119.","journal-title":"Pediatrics"},{"key":"42_CR30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1007\/s12519-011-0245-0","volume":"7","author":"M Cakir","year":"2011","unstructured":"Cakir M, Ozgenc F, Yusekkaya HA, Ecevit CO, Yagci RV. Steroid response in moderate to severe pediatric ulcerative colitis: a single center\u2019s experience. World J Pediatr 2011;7:50\u201353.","journal-title":"World J Pediatr"},{"key":"42_CR31","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1053\/j.gastro.2010.02.047","volume":"138","author":"D Turner","year":"2010","unstructured":"Turner D, Mack D, Leleiko N, Walters TD, Uusoue K, Leach ST, et al. Severe pediatric ulcerative colitis: a prospective multicenter study of outcomes and predictors of response. Gastroenterology 2010;138:2282\u20132291.","journal-title":"Gastroenterology"},{"key":"42_CR32","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.jpedsurg.2013.03.006","volume":"48","author":"FL Gray","year":"2013","unstructured":"Gray FL, Turner CG, Zurakowski D, Bousvaros A, Linden BC, Shamberger RC, et al. Predictive value of the Pediatric Ulcerative Colitis Activity Index in the surgical management of ulcerative colitis. J Pediatr Surg 2013;48:1540\u20131545.","journal-title":"J Pediatr Surg"},{"key":"42_CR33","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.crohns.2011.05.003","volume":"5","author":"D Turner","year":"2011","unstructured":"Turner D, Mack DR, Hyams J, LeLeiko N, Otley A, Markowitz J, et al. C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitis. J Crohns Colitis 2011;5:423\u2013429.","journal-title":"J Crohns Colitis"},{"key":"42_CR34","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1136\/gutjnl-2013-305607","volume":"63","author":"C Rungoe","year":"2014","unstructured":"Rungoe C, Langholz E, Andersson M, Basit S, Nielsen NM, Wohlfahrt J, et al. Changes in medical treatment and surgery rates in inflammatory bowel disease: a nationwidecohort study 1979\u20132011. Gut 2014;63:1607\u20131616.","journal-title":"Gut"},{"key":"42_CR35","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1038\/ajg.2013.242","volume":"108","author":"A Peneau","year":"2013","unstructured":"Peneau A, Savoye G, Turck D, Dauchet L, Fumery M, Salleron J, et al. Mortality and cancer in pediatric-onset inflammatory bowel disease: a population-based study. Am J Gastroenterol 2013;108:1647\u20131653.","journal-title":"Am J Gastroenterol"}],"container-title":["World Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-015-0042-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12519-015-0042-2\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-015-0042-2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T07:01:11Z","timestamp":1567234871000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12519-015-0042-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10,11]]},"references-count":35,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["42"],"URL":"https:\/\/doi.org\/10.1007\/s12519-015-0042-2","relation":{},"ISSN":["1708-8569","1867-0687"],"issn-type":[{"value":"1708-8569","type":"print"},{"value":"1867-0687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,10,11]]}}}