{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T15:41:55Z","timestamp":1781710915622,"version":"3.54.5"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T00:00:00Z","timestamp":1450396800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Pediatr"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1007\/s12519-015-0064-9","type":"journal-article","created":{"date-parts":[[2015,12,18]],"date-time":"2015-12-18T12:53:28Z","timestamp":1450443208000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Predicting eczema severity beyond childhood"],"prefix":"10.1007","volume":"12","author":[{"given":"Kam Lun","family":"Hon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin-Ching K.","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Terence Chuen W.","family":"Poon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nga Hin","family":"Pong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Kwan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shirley","family":"Lau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuen-Chun","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hin-Hei","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Fan","family":"Leung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2015,12,18]]},"reference":[{"key":"64_CR1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1111\/j.1525-1470.2005.22303.x","volume":"22","author":"CL Carroll","year":"2005","unstructured":"Carroll CL, Balkrishnan R, Feldman SR, Fleischer AB Jr, Manuel JC. The burden of atopic dermatitis: impact on the patient, family, and society. Pediatr Dermatol 2005;22:192\u2013199.","journal-title":"Pediatr Dermatol"},{"key":"64_CR2","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.yapd.2007.03.013","volume":"54","author":"AK Leung","year":"2007","unstructured":"Leung AK, Hon KL, Robson WL. Atopic dermatitis. Adv Pediatr 2007;54:241\u2013273.","journal-title":"Adv Pediatr"},{"key":"64_CR3","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1136\/bmj.39405.503773.AD","volume":"335","author":"S Lewis-Jones","year":"2007","unstructured":"Lewis-Jones S, Mugglestone MA, Guideline Development Group. Management of atopic eczema in children aged up to 12 years: summary of NICE guidance. BMJ 2007;335:1263\u20131264.","journal-title":"BMJ"},{"key":"64_CR4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1007\/s12098-010-0042-0","volume":"77","author":"KL Hon","year":"2010","unstructured":"Hon KL, Tsang S, Wong CY, Tse PM, Wong C, To WH, et al. Atopy in children with eczema. Indian J Pediatr 2010;77:519\u2013522.","journal-title":"Indian J Pediatr"},{"key":"64_CR5","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.anai.2009.10.002","volume":"105","author":"JM Spergel","year":"2010","unstructured":"Spergel JM. From atopic dermatitis to asthma: the atopic march. Ann Allergy Asthma Immunol 2010;105:99\u2013106.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"64_CR6","first-page":"73","volume":"11","author":"KL Hon","year":"2012","unstructured":"Hon KL, Wang SS, Leung TF. The atopic march: from skin to the airways. Iran J Allergy Asthma Immunol 2012;11:73\u201377.","journal-title":"Iran J Allergy Asthma Immunol"},{"key":"64_CR7","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1007\/s12519-012-0354-4","volume":"8","author":"KL Hon","year":"2012","unstructured":"Hon KL, Wang SS, Wong WL, Poon WK, Mak KY, Leung TF. Skin prick testing in atopic eczema: atopic to what and at what age? World J Pediatr 2012;8:164\u2013168.","journal-title":"World J Pediatr"},{"key":"64_CR8","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1016\/j.jaci.2005.08.026","volume":"116","author":"HC Williams","year":"2005","unstructured":"Williams HC, Johansson SG. Two types of eczema\u2014or are there? J Allergy Clin Immunol 2005;116:1064\u20131066.","journal-title":"J Allergy Clin Immunol"},{"key":"64_CR9","first-page":"813","volume":"56","author":"SG Johansson","year":"2001","unstructured":"Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, et al. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force. Allergy 2001;56:813\u2013824.","journal-title":"An EAACI position statement from the EAACI nomenclature task force. Allergy"},{"key":"64_CR10","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1111\/j.1365-4632.2007.03407.x","volume":"46","author":"KL Hon","year":"2007","unstructured":"Hon KL, Lam MC, Leung TF, Wong KY, Chow CM, Fok TF, et al. Are age-specific high serum IgE levels associated with worse symptomatology in children with atopic dermatitis? Int J Dermatol 2007;46:1258\u20131262.","journal-title":"Int J Dermatol"},{"key":"64_CR11","first-page":"469","volume":"69","author":"HA Sampson","year":"1992","unstructured":"Sampson HA. Atopic dermatitis. Ann Allergy 1992;69:469\u2013479.","journal-title":"Ann Allergy"},{"key":"64_CR12","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1001\/archderm.1964.01590260047008","volume":"89","author":"HL Roth","year":"1964","unstructured":"Roth HL, Kierland RR. The natural history of atopic dermatitis. A 20-year follow-up study. Arch Dermatol 1964;89:209\u2013214.","journal-title":"A 20-year follow-up study. Arch Dermatol"},{"key":"64_CR13","doi-asserted-by":"crossref","first-page":"206","DOI":"10.2340\/0001555565206213","volume":"65","author":"I Rystedt","year":"1985","unstructured":"Rystedt I. Prognostic factors in atopic dermatitis. Acta Derm Venereol 1985;65:206\u2013213.","journal-title":"Acta Derm Venereol"},{"key":"64_CR14","first-page":"117","volume":"114","author":"I Rystedt","year":"1985","unstructured":"Rystedt I. Long term follow-up in atopic dermatitis. Acta Derm Venereol Suppl (Stockh) 1985;114:117\u2013120.","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"64_CR15","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1016\/S1081-1206(10)62852-9","volume":"83","author":"B Wuthrich","year":"1999","unstructured":"Wuthrich B. Clinical aspects, epidemiology, and prognosis of atopic dermatitis. Ann Allergy Asthma Immunol 1999;83:464\u2013470.","journal-title":"Ann Allergy Asthma Immunol"},{"key":"64_CR16","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1111\/j.1365-2133.1994.tb08532.x","volume":"131","author":"HC Williams","year":"1994","unstructured":"Williams HC, Burney PG, Pembroke AC, Hay RJ. The U.K. Working Party\u2019s Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation. Brit J Dermatol 1994;131:406\u2013416.","journal-title":"Brit J Dermatol"},{"key":"64_CR17","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1046\/j.1365-2133.2000.03300.x","volume":"142","author":"RM Emerson","year":"2000","unstructured":"Emerson RM, Charman CR, Williams HC. The Nottingham Eczema Severity Score: preliminary refinement of the Rajka and Langeland grading. Brit J Dermatol 2000;142:288\u2013297.","journal-title":"Brit J Dermatol"},{"key":"64_CR18","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1111\/j.1525-1470.2003.20601.x","volume":"20","author":"KL Hon","year":"2003","unstructured":"Hon KL, Ma KC, Wong E, Leung TF, Wong Y, Fok TF. Validation of a self-administered questionnaire in Chinese in the assessment of eczema severity. Pediatr Dermatol 2003;20:465\u2013469.","journal-title":"Pediatr Dermatol"},{"key":"64_CR19","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1007\/s11136-006-0019-7","volume":"15","author":"KL Hon","year":"2006","unstructured":"Hon KL, Kam WY, Lam MC, Leung TF, Ng PC. CDLQI, SCORAD and NESS: are they correlated? Qual Life Res 2006; 15:1551\u20131558.","journal-title":"Qual Life Res"},{"key":"64_CR20","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1046\/j.1365-2133.1998.02316.x","volume":"139","author":"RM Emerson","year":"1998","unstructured":"Emerson RM, Williams HC, Allen BR. Severity distribution of atopic dermatitis in the community and its relationship to secondary referral. Brit J Dermatol 1998;139:73\u201376.","journal-title":"Brit J Dermatol"},{"key":"64_CR21","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1111\/all.12112","volume":"68","author":"D Garmhausen","year":"2013","unstructured":"Garmhausen D, Hagemann T, Bieber T, Dimitriou I, Fimmers R, Diepgen T, et al. Characterization of different courses of atopic dermatitis in adolescent and adult patients. Allergy 2013;68:498\u2013506.","journal-title":"Allergy"},{"key":"64_CR22","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1080\/09546630510038938","volume":"16","author":"KL Hon","year":"2005","unstructured":"Hon KL, Ma KC, Wong Y, Leung TF, Fok TF. A survey of traditional Chinese medicine use in children with atopic dermatitis attending a paediatric dermatology clinic. J Dermatolog Treat 2005;16:154\u2013157.","journal-title":"J Dermatolog Treat"},{"key":"64_CR23","doi-asserted-by":"crossref","unstructured":"Spergel JM, Paller AS. Atopic dermatitis and the atopic march. J Allergy Clin Immol 2003;112:S118\u2013127.","DOI":"10.1016\/j.jaci.2003.09.033"},{"key":"64_CR24","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1744-313X.2009.00859.x","volume":"36","author":"G Ching","year":"2009","unstructured":"Ching G, Hon KL. Filaggrin null mutations in childhood atopic dermatitis among the Chinese. Int J Immunogenetics 2009;36:251\u2013254.","journal-title":"Int J Immunogenetics"},{"key":"64_CR25","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1038\/jid.2012.62","volume":"132","author":"SS Wang","year":"2012","unstructured":"Wang SS, Hon KL, Sy HY, Kong AP, Chan IH, Tse LY, et al. Interactions between genetic variants of FLG and chromosome 11q13 locus determine susceptibility for eczema phenotypes. J Invest Dermatol 2012;132:1930\u20131932.","journal-title":"J Invest Dermatol"},{"key":"64_CR26","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1111\/pai.12167","volume":"25","author":"SS Wang","year":"2014","unstructured":"Wang SS, Hon KL, Kong AP, Pong HN, Wong GW, Leung TF. Vitamin D deficiency is associated with diagnosis and severity of childhood atopic dermatitis. Pediatr Allergy Immunol 2014;25:30\u201335.","journal-title":"Pediatr Allergy Immunol"},{"key":"64_CR27","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1001\/archderm.136.6.763","volume":"136","author":"C Charman","year":"2000","unstructured":"Charman C, Williams H. Outcome measures of disease severity in atopic eczema. Arch Dermatol 2000;136:763\u2013769.","journal-title":"Arch Dermatol"},{"key":"64_CR28","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1046\/j.1365-2133.2002.04644.x","volume":"146","author":"CR Charman","year":"2002","unstructured":"Charman CR, Venn AJ, Williams HC. Reliability testing of the Six Area, Six Sign Atopic Dermatitis severity score. Brit J Dermatol 2002;146:1057\u20131060.","journal-title":"Brit J Dermatol"},{"key":"64_CR29","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1046\/j.1523-1747.2003.12251.x","volume":"120","author":"C Charman","year":"2003","unstructured":"Charman C, Chambers C, Williams H. Measuring atopic dermatitis severity in randomized controlled clinical trials: what exactly are we measuring? J Invest Dermatol 2003;120:932\u2013941.","journal-title":"J Invest Dermatol"},{"key":"64_CR30","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.0736-8046.2004.21203.x","volume":"21","author":"KL Hon","year":"2004","unstructured":"Hon KL. Skin diseases in Chinese children at a pediatric dermatology center. Pediatr Dermatol 2004;21:109\u2013112.","journal-title":"Pediatr Dermatol"},{"key":"64_CR31","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.jaci.2007.08.011","volume":"120","author":"J Schmitt","year":"2007","unstructured":"Schmitt J, Langan S, Williams HC. What are the best outcome measurements for atopic eczema? A systematic review. J Allergy Clin Immunol 2007;120:1389\u20131398.","journal-title":"J Allergy Clin Immunol"},{"key":"64_CR32","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1016\/j.jaci.2013.07.008","volume":"132","author":"J Schmitt","year":"2013","unstructured":"Schmitt J, Langan S, Deckert S, Svensson A, von Kobyletzki L, Thomas K, et al. Assessment of clinical signs of atopic dermatitis: a systematic review and recommendation. J Allergy Clin Immunol 2013;132:1337\u20131347.","journal-title":"J Allergy Clin Immunol"}],"container-title":["World Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-015-0064-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12519-015-0064-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-015-0064-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T05:52:07Z","timestamp":1718257927000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12519-015-0064-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,18]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["64"],"URL":"https:\/\/doi.org\/10.1007\/s12519-015-0064-9","relation":{},"ISSN":["1708-8569","1867-0687"],"issn-type":[{"value":"1708-8569","type":"print"},{"value":"1867-0687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,18]]}}}