{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T08:27:25Z","timestamp":1779179245842,"version":"3.51.4"},"reference-count":42,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T00:00:00Z","timestamp":1467158400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T00:00:00Z","timestamp":1467158400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["World J Pediatr"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1007\/s12519-016-0025-y","type":"journal-article","created":{"date-parts":[[2016,6,29]],"date-time":"2016-06-29T02:41:47Z","timestamp":1467168107000},"page":"320-326","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Incidence and consequences of varicella in children treated for cancer in Guatemala"],"prefix":"10.1007","volume":"12","author":[{"given":"Amy E. Caruso","family":"Brown","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edwin J.","family":"Asturias","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mario","family":"Melgar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Federico A.","family":"Antillon-Klussmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pamela","family":"Mettler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Myron J.","family":"Levin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,6,29]]},"reference":[{"key":"25_CR1","doi-asserted-by":"publisher","first-page":"2095","DOI":"10.1016\/S0140-6736(12)61728-0","volume":"380","author":"R Lozano","year":"2012","unstructured":"Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V, et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2095\u20132128.","journal-title":"Lancet"},{"key":"25_CR2","doi-asserted-by":"publisher","first-page":"4788","DOI":"10.1002\/cncr.26107","volume":"117","author":"S Gupta","year":"2011","unstructured":"Gupta S, Antillon FA, Bonilla M, Fu L, Howard SC, Ribeiro RC, et al. Treatment-related mortality in children with acute lymphoblastic leukemia in Central America. Cancer 2011;117:4788\u20134795.","journal-title":"Cancer"},{"key":"25_CR3","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.1016\/j.ejca.2011.10.009","volume":"48","author":"S Gupta","year":"2012","unstructured":"Gupta S, Bonilla M, Valverde P, Fu L, Howard SC, Ribeiro RC, et al. Treatment-related mortality in children with acute myeloid leukaemia in Central American: incidence, timing and predictors. Eur J Cancer 2012;48:1363\u20131369.","journal-title":"Eur J Cancer"},{"key":"25_CR4","doi-asserted-by":"publisher","first-page":"48","DOI":"10.1002\/(SICI)1096-911X(199701)28:1<48::AID-MPO9>3.0.CO;2-T","volume":"28","author":"Z Aziz","year":"1997","unstructured":"Aziz Z, Zahid M, Mahmood R, Maqbool S. Modified BFM protocol for childhood acute lymphoblastic leukemia: a retrospective analysis. Med Pediatr Oncol 1997;28:48\u201353.","journal-title":"Med Pediatr Oncol"},{"key":"25_CR5","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1023\/A:1008366814109","volume":"10","author":"S Advani","year":"1999","unstructured":"Advani S, Pai S, Venzon D, Adde M, Kurkure PK, Nair CN, et al. Acute lymphoblastic leukemia in India: an analysis of prognostic factors using a single treatment regimen. Ann Oncol 1999;10:167\u2013176.","journal-title":"Ann Oncol"},{"key":"25_CR6","doi-asserted-by":"publisher","first-page":"266","DOI":"10.1002\/mpo.1321","volume":"38","author":"V Laosombat","year":"2002","unstructured":"Laosombat V, Wongchanchailert M, Sattayasevana B, Wiriyasateinkul A, Watana-Arepornchai S. The treatment of children with acute lymphoblastic leukemia in Thailand. Med Pediatr Oncol 2002;38:266\u2013268.","journal-title":"Med Pediatr Oncol"},{"key":"25_CR7","doi-asserted-by":"publisher","first-page":"2471","DOI":"10.1001\/jama.291.20.2471","volume":"291","author":"SC Howard","year":"2004","unstructured":"Howard SC, Pedrosa M, Lins M, Pedrosa A, Pui CH, Ribeiro RC, et al. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004;291:2471\u20132475.","journal-title":"JAMA"},{"key":"25_CR8","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1016\/S0140-6736(03)14228-6","volume":"362","author":"ML Metzger","year":"2003","unstructured":"Metzger ML, Howard SC, Fu LC, Pe\u00f1a A, Stefan R, Hancock ML, et al. Outcomes of childhood acute lymphoblastic leukemia in resource-poor countries. Lancet 2003;362:706\u2013708.","journal-title":"Lancet"},{"key":"25_CR9","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1542\/peds.80.4.465","volume":"80","author":"S Feldman","year":"1987","unstructured":"Feldman S, Lott L. Varicella in children with cancer: impact of antiviral therapy and prophylaxis. Pediatrics 1987;80:465\u2013472.","journal-title":"Pediatrics"},{"key":"25_CR10","unstructured":"American Academy of Pediatrics. Varicella-zoster infections. In: Pickering LK, Baker CJ, Long S, McMillan JA, eds. Red Book Online: 2012 Report of the Committee on Infectious Diseases, 29th edition. Available at: http:\/\/aapredbook.aappublications.org\/content\/current (accessed September 21, 2014)."},{"key":"25_CR11","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1097\/00043426-199605000-00003","volume":"18","author":"K Buda","year":"1996","unstructured":"Buda K, Tubergen DG, Levin M. The frequency and consequences of varicella exposure and varicella infection in children receiving maintenance therapy for acute lymphoblastic leukemia. J Pediatr Hematol Oncol 1996;18:106\u2013112.","journal-title":"J Pediatr Hematol Oncol"},{"key":"25_CR12","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/infdis\/157.2.309","volume":"157","author":"G Nyerges","year":"1988","unstructured":"Nyerges G, Meszner Z, Gyarmati E, Kerpel-Fronius S. Acyclovir prevents dissemination of varicella in immunocompromised children. J Infect Dis 1988;157:309.","journal-title":"J Infect Dis"},{"key":"25_CR13","doi-asserted-by":"publisher","first-page":"199","DOI":"10.1097\/INF.0b013e3181bbf2a0","volume":"29","author":"SS Shah","year":"2010","unstructured":"Shah SS, Wood SM, Luan X, Ratner AJ. Decline in varicellarelated ambulatory visits and hospitalizations in the United States since routine immunization against varicella. Ped Infect Dis J 2010;29:199\u2013204.","journal-title":"Ped Infect Dis J"},{"key":"25_CR14","doi-asserted-by":"publisher","first-page":"214","DOI":"10.1542\/peds.2010-3385","volume":"128","author":"M Marin","year":"2011","unstructured":"Marin M, Zhang JX, Seward JF. Near elimination of varicella deaths in the US after implementation of the vaccination program. Pediatrics 2011;128:214\u2013220.","journal-title":"Pediatrics"},{"key":"25_CR15","doi-asserted-by":"publisher","first-page":"866","DOI":"10.1086\/590358","volume":"29","author":"AL Adler","year":"2008","unstructured":"Adler AL, Casper C, Boeckh M, Heath J, Zerr DM. An outbreak of varicella with likely breakthrough disease in a population of pediatric cancer patients. Infect Control Hosp Epidemiol 2008;29:866\u2013870.","journal-title":"Infect Control Hosp Epidemiol"},{"key":"25_CR16","doi-asserted-by":"publisher","first-page":"402","DOI":"10.1016\/j.vaccine.2012.10.100","volume":"31","author":"A Paternina-Caicedo","year":"2013","unstructured":"Paternina-Caicedo A, De la Hoz-Restrepo F, Gamboa-Garay O, Casta\u00f1eda-Orjuela C, Velandia-Gonz\u00e1lez M, Alvis-Guzm\u00e1n N. How cost effective is universal varicella vaccination in developing countries? A case-study from Colombia. Vaccine 2013;31:402\u2013409.","journal-title":"Vaccine"},{"key":"25_CR17","doi-asserted-by":"publisher","first-page":"2071","DOI":"10.1002\/pbc.25060","volume":"61","author":"M De Pernillo","year":"2014","unstructured":"De Pernillo M, Rivas S, Fuentes L, Antill\u00f3n F, Barr RD. Measurement of socio-economic status in families of children with cancer in Guatemala. Pediatr Blood Cancer 2014;61:2071\u20132073.","journal-title":"Pediatr Blood Cancer"},{"key":"25_CR18","doi-asserted-by":"publisher","first-page":"911","DOI":"10.1002\/pbc.24377","volume":"60","author":"F Antill\u00f3n","year":"2013","unstructured":"Antill\u00f3n F, Rossi E, Molina AL, Sala A, Pencharz P, Valsecchi MG, Barr R. Nutritional status of children during treatment for acute lymphoblastic leukemia in Guatemala. Pediatr Blood Cancer 2013;60:911\u2013915.","journal-title":"Pediatr Blood Cancer"},{"key":"25_CR19","first-page":"227","volume":"164","author":"Y Quintana","year":"2011","unstructured":"Quintana Y, Patel AN, Naidu PE, Howard SC, Antillon FA, Ribeiro RC. POND4Kids: a web-based pediatric cancer database for hospital-based cancer registration and clinical collaboration. Stud Health Technol Inform 2011;164:227\u2013231.","journal-title":"Stud Health Technol Inform"},{"key":"25_CR20","doi-asserted-by":"publisher","first-page":"A15","DOI":"10.1186\/1471-2105-13-S12-A15","volume":"13","author":"PA Harris","year":"2012","unstructured":"Harris PA. Research electronic data capture (REDCap)\u2013planning, collecting and managing data for clinical and translational research. BMC Bioinformatics 2012;13:A15.","journal-title":"BMC Bioinformatics"},{"key":"25_CR21","unstructured":"World Health Organization. WHO SAS macro package, 2007. http:\/\/www.who.int\/growthref\/tools\/readme_sas.pdf (accessed August 3, 2013)."},{"key":"25_CR22","unstructured":"R Development Core Team. R: A language and environment for statistical computing. Version 2. 15. 3. http:\/\/www.Rproject.org\/ (accessed August 3, 2013)."},{"key":"25_CR23","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1097\/INF.0b013e31826ff3a5","volume":"31","author":"A Bardach","year":"2012","unstructured":"Bardach A, Cafferata ML, Klein K, Cormick G, Gibbons L, Ruvinsky S. Incidence and use of resources for chickenpox and herpes zoster in Latin America and the Caribbean\u2013A systematic review and meta-analysis. Pediatr Infectious Dis J 2012;31:1263\u20131268.","journal-title":"Pediatr Infectious Dis J"},{"key":"25_CR24","doi-asserted-by":"publisher","first-page":"759","DOI":"10.4067\/S0034-98872003000700007","volume":"131","author":"I Folatre","year":"2003","unstructured":"Folatre I, Zolezzi P, Schmidt D, Mar\u00edn F, T\u00e4ger M. Infections caused by Varicella Zoster virus in children with cancer aged less than 15 years old. Rev Med Chil 2003;131:759\u2013764. [In Spanish]","journal-title":"Rev Med Chil"},{"key":"25_CR25","doi-asserted-by":"publisher","first-page":"2094","DOI":"10.1200\/JCO.2011.38.9924","volume":"30","author":"S Bhatia","year":"2012","unstructured":"Bhatia S, Landier W, Shangguan M, Hageman L, Schaible AN, Carter AR, et al. Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the Children\u2019s Oncology Group. J Clin Oncol 2012;30:2094\u20132101.","journal-title":"J Clin Oncol"},{"key":"25_CR26","doi-asserted-by":"publisher","first-page":"S71","DOI":"10.1086\/522156","volume":"197","author":"D Guris","year":"2008","unstructured":"Guris D, Jumaan AO, Mascola L, Watson BM, Zhang JX, Chaves SS, et al. Changing varicella epidemiology in active surveillance sites\u2013United States, 1995-2005. J Infect Dis 2008;197:S71\u2013S75.","journal-title":"J Infect Dis"},{"key":"25_CR27","doi-asserted-by":"publisher","first-page":"e1134","DOI":"10.1542\/peds.2013-0863","volume":"132","author":"SR Bialek","year":"2013","unstructured":"Bialek SR, Perella D, Zhang J, Mascola L, Viner K, Jackson C, et al. Impact of a routine two-dose varicella vaccination program on varicella epidemiology. Pediatrics 2013;132:e1134\u2013e1140.","journal-title":"Pediatrics"},{"key":"25_CR28","doi-asserted-by":"publisher","first-page":"571","DOI":"10.1016\/S0891-5520(05)70313-5","volume":"10","author":"M Wharton","year":"1996","unstructured":"Wharton M. The epidemiology of varicella-zoster virus infections. Inf Dis Clinics North America 1996;10:571\u2013581.","journal-title":"Inf Dis Clinics North America"},{"key":"25_CR29","unstructured":"Joint Committee on Vaccination and Immunisation. Statement on varicella and herpes zoster vaccines. Available from: http:\/\/webarchive.nationalarchives.gov.uk\/20120907090205\/http:\/www.dh.gov.uk\/prod_consum_dh\/groups\/dh_digitalassets\/@dh\/@ab\/documents\/digitalasset\/dh_133599. pdf (accessed March 12, 2014)."},{"key":"25_CR30","doi-asserted-by":"crossref","unstructured":"Macartney K, McIntyre P. Vaccines for post-exposure prophylaxis against varicella (chickenpox) in children and adults. Cochrane Database Syst Rev 2008;(3):CD001833.","DOI":"10.1002\/14651858.CD001833.pub2"},{"key":"25_CR31","doi-asserted-by":"publisher","first-page":"S200","DOI":"10.1086\/522133","volume":"197","author":"MJ Levin","year":"2008","unstructured":"Levin MJ. Varicella vaccination of immunocompromised children. J Infect Dis 2008;197:S200\u2013S206.","journal-title":"J Infect Dis"},{"key":"25_CR32","first-page":"1","volume":"56","author":"M Marin","year":"2007","unstructured":"Marin M, G\u00fcris D, Chaves SS, Schmid S, Seward JF; Advisory Committee on Immunization Practices, Centers for Disease Control and Prevention (CDC). Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2007;56:1\u201340.","journal-title":"Prevention of varicella: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep"},{"key":"25_CR33","doi-asserted-by":"publisher","first-page":"1375","DOI":"10.1093\/infdis\/jit344","volume":"208","author":"KM Mullane","year":"2013","unstructured":"Mullane KM, Winston DJ, Wertheim MS, Betts RF, Poretz DM, Camacho LH, et al. Safety and immunogenicity of heat-treated zoster vaccine (ZVHT) in immunocompromised adults. J Infect Dis 2013;208:1375\u20131385.","journal-title":"J Infect Dis"},{"key":"25_CR34","doi-asserted-by":"publisher","first-page":"1280","DOI":"10.1093\/infdis\/jis497","volume":"206","author":"I Leroux-Roels","year":"2012","unstructured":"Leroux-Roels I, Leroux-Roels G, Clement F, Vandepapeli\u00e8re P, Vassilev V, Ledent E, et al. A phase I\/II clinical trial evaluating safety and immunogenicity of a varicella zoster glycoprotein E subunit vaccine candidate in young and older adults. J Infect Dis 2012;206:1280\u20131290.","journal-title":"J Infect Dis"},{"key":"25_CR35","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1542\/peds.97.1.150","volume":"97","author":"Y Ishida","year":"1996","unstructured":"Ishida Y, Tauchi H, Higaki A, Yokota-Outou Y, Kida K. Postexposure prophylaxis of varicella in children with leukemia by oral acyclovir. Pediatrics 1996;97:150.","journal-title":"Pediatrics"},{"key":"25_CR36","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1542\/peds.92.2.219","volume":"92","author":"Y Asano","year":"1993","unstructured":"Asano Y, Yoshikawa T, Suga S, Kobayashi I, Nakashima T, Yazaki T, et al. Postexposure prophylaxis of varicella in family contact by oral acyclovir. Pediatrics 1993;92:219\u2013222.","journal-title":"Pediatrics"},{"key":"25_CR37","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1136\/adc.69.6.639","volume":"69","author":"S Suga","year":"1993","unstructured":"Suga S, Yoshikawa T, Ozaki T, Asano Y. Effect of oral acyclovir against primary and secondary viraemia in incubation period of varicella. Arch Dis Child 1993;69:639\u2013642.","journal-title":"Arch Dis Child"},{"key":"25_CR38","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1016\/j.jhin.2009.01.020","volume":"72","author":"M Shinjoh","year":"2009","unstructured":"Shinjoh M, Takahashi T. Varicella zoster exposure on paediatric wards between 2000 and 2007: safe and effective postexposure prophylaxis with oral aciclovir. J Hosp Infec 2009;72:163\u2013168.","journal-title":"J Hosp Infec"},{"key":"25_CR39","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1097\/QCO.0b013e328345d666","volume":"24","author":"JPH Fisher","year":"2011","unstructured":"Fisher JPH, Bate J, Hambleton S. Preventing varicella in children with malignancies: what is the evidence? Curr Opin Infect Dis 2011;24:203\u2013211.","journal-title":"Curr Opin Infect Dis"},{"key":"25_CR40","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1136\/adc.2010.209650","volume":"96","author":"J Bate","year":"2011","unstructured":"Bate J, Chisholm J, Heath PT, Breuer J, Skinner R, Manley S, et al. PEPtalk: postexposure prophylaxis against varicella in children with cancer. Arch Dis Child 2011;96:841\u2013845.","journal-title":"Arch Dis Child"},{"key":"25_CR41","doi-asserted-by":"publisher","first-page":"1383","DOI":"10.1093\/infdis\/171.5.1383","volume":"171","author":"MJ Levin","year":"1995","unstructured":"Levin MJ, Rotbart HA, Hayward AR. Immune response to varicella-zoster five years after acyclovir therapy of childhood varicella. J Infect Dis 1995;171:1383\u20131384.","journal-title":"J Infect Dis"},{"key":"25_CR42","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/82_2010_31","volume-title":"Varicella-zoster virus: current topics in microbiology and immunology","author":"A Weinberg","year":"2010","unstructured":"Weinberg A, Levin MJ. VZV T cell-mediated immunity. In: Arvin A, Abendroth A, eds. Varicella-zoster virus: current topics in microbiology and immunology. Berlin: Springer Verlag, 2010: 341\u2013358."}],"container-title":["World Journal of Pediatrics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-016-0025-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12519-016-0025-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-016-0025-y","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12519-016-0025-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T05:05:22Z","timestamp":1744175122000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12519-016-0025-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,6,29]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["25"],"URL":"https:\/\/doi.org\/10.1007\/s12519-016-0025-y","relation":{},"ISSN":["1708-8569","1867-0687"],"issn-type":[{"value":"1708-8569","type":"print"},{"value":"1867-0687","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,6,29]]},"assertion":[{"value":"26 November 2014","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 February 2015","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 June 2016","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}}]}}