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This study aims to develop a method to more accurately predict final height.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>One hundred and seventy-three girls with menarche from August 2018 to June 2023 were analyzed retrospectively. BAs in Greulich and Pyle and Hoerr knee atlases were evaluated. Knee radiomic features were extracted using PyRadiomics; least absolute shrinkage and selection operator regression was utilized to develop radiomic scores of the distal femur and proximal tibia. Ordinary least squares regression with stepwise selection was used to build a multilinear equation. This was further compared with traditional methods in fivefold cross-validation (CV\u2009=\u20095) using residual distribution and Bland\u2013Altman agreement analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Height gain in our Chinese cohort after menarche was 8.94\u2009\u00b1\u20092.99\u00a0cm. A stepwise multilinear equation was built with height at menarche, BA of GP and radiomic score of the distal femur (\n                      <jats:italic>R<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u20090.733,\n                      <jats:italic>F<\/jats:italic>\n                      statistic\u2009=\u2009115.1,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Compared with traditional methods, a multilinear equation displayed the lowest residuals (residual range: \u2212\u00a05.677\u00a0cm to\u2009+\u20096.444\u00a0cm) and best Bland\u2013Altman agreement (the mean difference: \u2212\u00a00.01\u00a0cm, 95% limits of agreement: \u2212\u00a03.96 to\u2009+\u20093.93\u00a0cm).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A robust linear regression model that incorporates knee radiomic scores, BA of GP, height at menarche, and father\u2019s height demonstrated the best final height prediction in our cohort. This research is an innovative application of radiomic score of the distal femur to final height prediction. Further validation is warranted to test robustness across populations and scenarios.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Graphic abstract<\/jats:title>\n                  <\/jats:sec>","DOI":"10.1007\/s12519-025-01002-5","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T18:38:10Z","timestamp":1765651090000},"page":"129-141","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Final height prediction of girls at menarche: a combined model using left hand and wrist bone age, knee radiomic scores, and clinical characteristics"],"prefix":"10.1007","volume":"22","author":[{"given":"Xue-Qiong","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Rou","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei-Han","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guo-Ying","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2186-759X","authenticated-orcid":false,"given":"Xiu-Min","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,12,13]]},"reference":[{"key":"1002_CR1","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1186\/1477-7827-8-115","volume":"8","author":"O Karapanou","year":"2010","unstructured":"Karapanou O, Papadimitriou A. 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Authors\u00a0Yao Chen and Guo-Ying Chang are members of the Youth Editorial Board Member for\n                      World Journal of Pediatrics\n                      . The paper was handled by the other Editor and has undergone rigorous peer review process. Authors Yao Chen and Guo-Ying Chang were excluded from all editorial decisions related to this manuscript.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the Institutional Ethics Committee of Shanghai Children\u2019s Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China (approval number: SCMCIRB-K2025024-1). The ethics committee granted written consent waiver as this retrospective study used de-identified clinical cases obtained during prior diagnostic\/therapeutic procedures.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}}]}}