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Author Si-Tang Gong is a member of the Editorial Board for\n                      World Journal of Pediatrics\n                      . The paper was handled by the other editor and has undergone a rigorous peer review process. Author Si-Tang Gong was not involved in the journal\u2019s review or decisions related to this manuscript. The authors have no conflicts of interest to declare.","order":1,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was conducted according to the Declaration of Helsinki for biomedical research involving humans (version 2008)\u00a0and the criteria for the quality control of clinical trials of drugs. It\u00a0was approved by the Regional Scientific Ethical Committee of Guangzhou Women and Children\u2019s Medical Center (No. 2018101108).\u00a0Ethical approval was obtained from the Scientific Ethics Committees of all the participating hospitals, and written informed consent was obtained from parents or legal guardians before enrollment. The study was registered in the Chinese Clinical Trial Registry prior to initiation (ChiCTR1800020375).","order":2,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}}]}}