{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T19:41:06Z","timestamp":1787859666903,"version":"build-2784847793"},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2011,5,19]],"date-time":"2011-05-19T00:00:00Z","timestamp":1305763200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Reprod Medicine &amp; Biology"],"published-print":{"date-parts":[[2011,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To investigate potential indicators of in vitro fertilization (IVF) treatment outcome for female infertility patients aged \u2265 40 years based on the clinical course.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We retrospectively examined results of 111 female infertility patients aged \u2265 40 years undergoing IVF treatment. We investigated the relationship between treatment cycle cancellation and the final outcome of IVF treatment in female infertility patients aged \u2265 40 years.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 44 pregnancies were achieved. Overall pregnancy rate per initiated treatment cycle was 12.1%, and 24 spontaneous abortions occurred (54.5%). No woman aged \u2265 45 years achieved pregnancy. No patients conceived after 10 treatment cycles while 42 (11.5%) oocyte pick\u2010up cycles and 120 (33.0%) embryo transfer cycles were canceled. Investigation of correlation with treatment cycle cancellation revealed that patients who experienced embryo transfer cancellation had a high spontaneous abortion rate while only a few patients who experienced oocyte pick\u2010up cancellation achieved pregnancy and even fewer achieved a successful outcome.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Our study suggests that, in addition to patient age and number of treatment cycles, cancellation of treatment cycle also provides another useful indicator for pregnancy outcome.<\/jats:p><\/jats:sec>","DOI":"10.1007\/s12522-011-0089-2","type":"journal-article","created":{"date-parts":[[2011,5,18]],"date-time":"2011-05-18T02:41:18Z","timestamp":1305686478000},"page":"179-184","source":"Crossref","is-referenced-by-count":2,"title":["Cancellation of in vitro fertilization treatment cycles predicts treatment outcome in female infertility patients aged 40 years or older"],"prefix":"10.1002","volume":"10","author":[{"given":"Kouhei","family":"Sugimoto","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Hashimoto","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eri","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukiyo","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takayuki","family":"Haino","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koji","family":"Kusuhara","sequence":"additional","affiliation":[{"name":"Kusuhara Ladies Clinic  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tadao","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology The Jikei University School of Medicine  3\u201025\u20108 Nishi\u2010Shinbashi, Minato\u2010ku 105\u20108461 Tokyo 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