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We report a case of a 28 year old gravida 0 with recurrent Stage IIB invasive ductal breast carcinoma who managed to conceive twice despite showing clinical and biochemical signs of decreased ovarian reserve following treatment with chemotherapy and radiation. This case illustrates the potential for fertility in a patient with breast cancer despite chemotherapy\u2010related amenorrhea and undetectable anti\u2010M\u00fcllerian hormone levels. It exemplifies the imprecise nature of all clinical tests used to predict future fertility in breast cancer patients post\u2010treatment. It should remind all providers to be careful in basing recommendations for childbearing on these surrogate endpoints.<\/jats:p>","DOI":"10.1007\/s12522-012-0133-x","type":"journal-article","created":{"date-parts":[[2012,7,19]],"date-time":"2012-07-19T00:39:28Z","timestamp":1342658368000},"page":"35-38","source":"Crossref","is-referenced-by-count":5,"title":["Pregnancy despite ovarian insufficiency in a patient with breast cancer"],"prefix":"10.1002","volume":"12","author":[{"given":"Erica B.","family":"Mahany","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Medical Center  622 W 168th St. PH\u201016 10032 New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dawn L.","family":"Hershman","sequence":"additional","affiliation":[{"name":"Department of Medicine Columbia University Medical Center  622 W 168th St. PH\u20108 10032 New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark V.","family":"Sauer","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Medical Center  622 W 168th St. PH\u201016 10032 New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet M.","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Columbia University Medical Center  622 W 168th St. PH\u201016 10032 New York NY USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,7,19]]},"reference":[{"key":"e_1_2_6_2_1","unstructured":"Howlader N Noone AM Krapcho M Neyman N Aminou R Waldron W Altekruse SF et al. 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