{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T23:51:01Z","timestamp":1782949861086,"version":"3.54.5"},"reference-count":51,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2018,8,29]],"date-time":"2018-08-29T00:00:00Z","timestamp":1535500800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Anat Sci Int"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1007\/s12565-018-0457-7","type":"journal-article","created":{"date-parts":[[2018,8,30]],"date-time":"2018-08-30T00:28:39Z","timestamp":1535588919000},"page":"119-127","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":56,"title":["Neuroprotective effect of crocin on substantia nigra in MPTP-induced Parkinson\u2019s disease model of mice"],"prefix":"10.1007","volume":"94","author":[{"given":"Parisa","family":"Haeri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Mohammadipour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Heidari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Ebrahimzadeh-bideskan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2018,8,29]]},"reference":[{"issue":"1","key":"457_CR1","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1186\/s12906-017-1731-2","volume":"17","author":"S Ahn","year":"2017","unstructured":"Ahn S et al (2017) Effects of a combination treatment of KD5040 and l-dopa in a mouse model of Parkinson\u2019s disease. BMC Complement Altern Med 17(1):220","journal-title":"BMC Complement Altern Med"},{"issue":"4","key":"457_CR2","doi-asserted-by":"publisher","first-page":"823","DOI":"10.3233\/NRE-172196","volume":"41","author":"MD Al-Jarrah","year":"2017","unstructured":"Al-Jarrah MD, Erekat NS (2017) Parkinson disease-induced upregulation of apoptotic mediators could be attenuated in the skeletal muscle following chronic exercise training. NeuroRehabilitation 41(4):823\u2013830","journal-title":"NeuroRehabilitation"},{"issue":"3","key":"457_CR3","first-page":"175","volume":"29","author":"H Aung","year":"2007","unstructured":"Aung H et al (2007) Crocin from Crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells. Exp Oncol 29(3):175\u2013180","journal-title":"Exp Oncol"},{"issue":"7","key":"457_CR4","first-page":"644","volume":"18","author":"F Bagheri-abassi","year":"2015","unstructured":"Bagheri-abassi F et al (2015) The effect of silver nanoparticles on apoptosis and dark neuron production in rat hippocampus. Iran J Basic Med Sci 18(7):644\u2013648","journal-title":"Iran J Basic Med Sci"},{"key":"457_CR5","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1007\/s11011-018-0194-6","volume":"33","author":"F Baghishani","year":"2018","unstructured":"Baghishani F (2018) The effects of tramadol administration on hippocampal cell apoptosis, learning and memory in adult rats and neuroprotective effects of crocin. Metab Brain Dis 33:907\u2013916","journal-title":"Metab Brain Dis"},{"issue":"3","key":"457_CR6","doi-asserted-by":"publisher","first-page":"551","DOI":"10.3390\/ijms18030551","volume":"18","author":"R Cacabelos","year":"2017","unstructured":"Cacabelos R (2017) Parkinson\u2019s disease: from pathogenesis to pharmacogenomics. Int J Mol Sci 18(3):551","journal-title":"Int J Mol Sci"},{"key":"457_CR7","first-page":"239","volume":"27","author":"D Catarzi","year":"2007","unstructured":"Catarzi D, Colotta V, Varana F (2007) Competitive AMPA receptor antagonists. Med Res 27:239\u2013278","journal-title":"Med Res"},{"issue":"1","key":"457_CR8","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.jneuroim.2009.09.003","volume":"216","author":"YX Chao","year":"2009","unstructured":"Chao YX, He BP, Tay SSW (2009) Mesenchymal stem cell transplantation attenuates blood brain barrier damage and neuroinflammation and protects dopaminergic neurons against MPTP toxicity in the substantia nigra in a model of Parkinson\u2019s disease. J Neuroimmunol 216(1):39\u201350","journal-title":"J Neuroimmunol"},{"issue":"10","key":"457_CR9","first-page":"958","volume":"18","author":"SA Dorri","year":"2015","unstructured":"Dorri SA et al (2015) Involvement of brain-derived neurotrophic factor (BDNF) on malathion induced depressive-like behavior in subacute exposure and protective effects of crocin. Iran J Basic Med Sci 18(10):958\u2013966","journal-title":"Iran J Basic Med Sci"},{"key":"457_CR10","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.cbi.2016.01.014","volume":"247","author":"NM Elsherbiny","year":"2016","unstructured":"Elsherbiny NM et al (2016) Crocin protects against doxorubicin-induced myocardial toxicity in rats through down-regulation of inflammatory and apoptic pathways. Chem Biol Interact 247:39\u201348","journal-title":"Chem Biol Interact"},{"issue":"1","key":"457_CR11","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.jchemneu.2005.04.004","volume":"30","author":"SR Emmett","year":"2005","unstructured":"Emmett SR, Greenfield SA (2005) Correlation between dopaminergic neurons, acetylcholinesterase and nicotinic acetylcholine receptors containing the \u03b13-or \u03b15-subunit in the rat substantia nigra. J Chem Neuroanat 30(1):34\u201344","journal-title":"J Chem Neuroanat"},{"issue":"4","key":"457_CR12","doi-asserted-by":"publisher","first-page":"678","DOI":"10.1002\/ptr.6017","volume":"32","author":"R Fisher","year":"2018","unstructured":"Fisher R et al (2018) The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson\u2019s disease. Phytother Res 32(4):678\u2013687","journal-title":"Phytother Res"},{"key":"457_CR13","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.brainres.2008.08.069","volume":"1239","author":"F Gallyas","year":"2008","unstructured":"Gallyas F, Kiglics V, Baracskay P, Juh\u00e1sz G, Czurk\u00f3 A (2008) The mode of death of epilepsy-induced \u201cdark\u201d neurons is neither necrosis nor apoptosis: an electron-microscopic study. Brain Res 1239:207\u2013215","journal-title":"Brain Res"},{"issue":"6","key":"457_CR14","doi-asserted-by":"publisher","first-page":"2369","DOI":"10.1523\/JNEUROSCI.20-06-02369.2000","volume":"20","author":"SN Haber","year":"2000","unstructured":"Haber SN, Fudge JL, McFarland NR (2000) Striatonigrostriatal pathways in primates form an ascending spiral from the shell to the dorsolateral striatum. J Neurosci 20(6):2369\u20132382","journal-title":"J Neurosci"},{"issue":"4","key":"457_CR15","first-page":"195","volume":"14","author":"J Hami","year":"2015","unstructured":"Hami J et al (2015) Effects of l-arginine pre-treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson\u2019s diseases in Balb\/c mice. Iran J Neurol 14(4):195\u2013203","journal-title":"Iran J Neurol"},{"key":"457_CR16","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.nbd.2012.10.011","volume":"51","author":"DN Hauser","year":"2013","unstructured":"Hauser DN, Hastings TG (2013) Mitochondrial dysfunction and oxidative stress in Parkinson\u2019s disease and monogenic parkinsonism. Neurobiol Dis 51:35\u201342","journal-title":"Neurobiol Dis"},{"issue":"4","key":"457_CR17","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1007\/s12031-016-0831-7","volume":"60","author":"WF Hilario","year":"2016","unstructured":"Hilario WF et al (2016) Cholinergic and dopaminergic alterations in nigrostriatal neurons are involved in environmental enrichment motor protection in a mouse model of Parkinson\u2019s disease. J Mol Neurosci 60(4):453\u2013464","journal-title":"J Mol Neurosci"},{"issue":"1","key":"457_CR18","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1007\/BF00505805","volume":"313","author":"GK Hodge","year":"1980","unstructured":"Hodge GK, Butcher LL (1980) Pars compacta of the substantia nigra modulates motor activity but is not involved importantly in regulating food and water intake. Naunyn-Schmiedebergs Arch Pharmacol 313(1):51\u201367","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"issue":"6","key":"457_CR19","doi-asserted-by":"crossref","first-page":"35","DOI":"10.21315\/mjms2016.23.6.4","volume":"23","author":"M Hosseini","year":"2016","unstructured":"Hosseini M et al (2016) The effects of crocin on 6-OHDA-induced oxidative\/nitrosative damage and motor behaviour in hemiparkinsonian rats. Malays J Med Sci MJMS 23(6):35\u201343","journal-title":"Malays J Med Sci MJMS"},{"key":"457_CR20","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1007\/s13318-017-0449-3","volume":"43","author":"A Hosseini","year":"2017","unstructured":"Hosseini A, Razavi BM, Hosseinzadeh H (2017) Pharmacokinetic properties of saffron and its active components. Eur J Drug Metab Pharmacokinet 43:383\u2013390","journal-title":"Eur J Drug Metab Pharmacokinet"},{"issue":"52","key":"457_CR21","doi-asserted-by":"publisher","first-page":"627","DOI":"10.4103\/pm.pm_470_16","volume":"13","author":"L Hosseinzadeh","year":"2017","unstructured":"Hosseinzadeh L et al (2017) Bioassay-guided isolation of neuroprotective fatty acids from Nigella sativa against 1-methyl-4-phenylpyridinium-induced neurotoxicity. Pharmacognosy magazine 13(52):627\u2013633","journal-title":"Pharmacognosy magazine"},{"issue":"3","key":"457_CR22","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1007\/s12565-017-0419-5","volume":"93","author":"Z Jalayeri-Darbandi","year":"2018","unstructured":"Jalayeri-Darbandi Z et al (2018) The effect of methamphetamine exposure during pregnancy and lactation on hippocampal doublecortin expression, learning and memory of rat offspring. Anat Sci Int 93(3):351\u2013363","journal-title":"Anat Sci Int"},{"issue":"4","key":"457_CR23","doi-asserted-by":"publisher","first-page":"628","DOI":"10.1016\/j.neuro.2006.03.002","volume":"27","author":"BS Jortner","year":"2006","unstructured":"Jortner BS (2006) The return of the dark neuron. A histological artifact complicating contemporary neurotoxicologic evaluation. Neurotoxicology 27(4):628\u2013634","journal-title":"Neurotoxicology"},{"issue":"1","key":"457_CR24","doi-asserted-by":"publisher","first-page":"83","DOI":"10.1186\/1742-2094-7-83","volume":"7","author":"F L\u2019Episcopo","year":"2010","unstructured":"L\u2019Episcopo F et al (2010) Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson\u2019s disease. J Neuroinflammation 7(1):83","journal-title":"J Neuroinflammation"},{"key":"457_CR25","doi-asserted-by":"publisher","first-page":"22","DOI":"10.3389\/fnsyn.2014.00022","volume":"6","author":"SAO Lim","year":"2014","unstructured":"Lim SAO, Kang UJ, McGehee DS (2014) Striatal cholinergic interneuron regulation and circuit effects. Front Synaptic Neurosci 6:22","journal-title":"Front Synaptic Neurosci"},{"issue":"5","key":"457_CR26","doi-asserted-by":"publisher","first-page":"e62905","DOI":"10.1371\/journal.pone.0062905","volume":"8","author":"Y Liu","year":"2013","unstructured":"Liu Y et al (2013) Targeting caspase-3 as dual therapeutic benefits by RNAi facilitating brain-targeted nanoparticles in a rat model of Parkinson\u2019s disease. PLoS One 8(5):e62905","journal-title":"PLoS One"},{"issue":"12","key":"457_CR27","doi-asserted-by":"publisher","first-page":"1945","DOI":"10.4103\/1673-5374.221147","volume":"12","author":"B Martinez","year":"2017","unstructured":"Martinez B, Peplow PV (2017) MicroRNAs in Parkinson\u2019s disease and emerging therapeutic targets. Neural Regen Res 12(12):1945\u20131959","journal-title":"Neural Regen Res"},{"key":"457_CR28","doi-asserted-by":"publisher","first-page":"108","DOI":"10.1016\/j.brainres.2009.09.107","volume":"1305","author":"N Matsui","year":"2009","unstructured":"Matsui N et al (2009) Magnolol protects against MPTP\/MPP\u2009+\u2009-induced toxicity via inhibition of oxidative stress in in vivo and in vitro models of Parkinson\u2019s disease. Brain Res 1305:108\u2013117","journal-title":"Brain Res"},{"issue":"1","key":"457_CR29","doi-asserted-by":"publisher","first-page":"296","DOI":"10.3892\/ol.2016.5383","volume":"13","author":"F Meng","year":"2017","unstructured":"Meng F et al (2017) Neuroprotective effect of matrine on MPTP-induced Parkinson\u2019s disease and on Nrf2 expression. Oncol Lett 13(1):296\u2013300","journal-title":"Oncol Lett"},{"issue":"1","key":"457_CR30","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1016\/S0304-3940(99)00463-2","volume":"270","author":"M Mogi","year":"1999","unstructured":"Mogi M et al (1999) Brain-derived growth factor and nerve growth factor concentrations are decreased in the substantia nigra in Parkinson\u2019s disease. Neurosci Lett 270(1):45\u201348","journal-title":"Neurosci Lett"},{"issue":"1","key":"457_CR31","doi-asserted-by":"publisher","first-page":"14","DOI":"10.4103\/ajm.AJM_70_17","volume":"8","author":"E Mohammadi","year":"2018","unstructured":"Mohammadi E et al (2018) Protective effect of crocin against d-galactose-induced aging in mice. Avicenna J Phytomed 8(1):14\u201323","journal-title":"Avicenna J Phytomed"},{"issue":"2","key":"457_CR32","doi-asserted-by":"publisher","first-page":"617","DOI":"10.1016\/j.etap.2014.01.014","volume":"37","author":"A Mohammadipour","year":"2014","unstructured":"Mohammadipour A et al (2014) Maternal exposure to titanium dioxide nanoparticles during pregnancy; impaired memory and decreased hippocampal cell proliferation in rat offspring. Environ Toxicol Pharmacol 37(2):617\u2013625","journal-title":"Environ Toxicol Pharmacol"},{"issue":"5","key":"457_CR33","doi-asserted-by":"publisher","first-page":"4904","DOI":"10.1007\/s11356-017-0842-0","volume":"25","author":"L Mohammadzadeh","year":"2018","unstructured":"Mohammadzadeh L et al (2018) Neuroprotective potential of crocin against malathion-induced motor deficit and neurochemical alterations in rats. Environ Sci Pollut Res 25(5):4904\u20134914","journal-title":"Environ Sci Pollut Res"},{"key":"457_CR34","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1016\/j.expneurol.2015.07.024","volume":"273","author":"RB Mounsey","year":"2015","unstructured":"Mounsey RB et al (2015) Increasing levels of the endocannabinoid 2-AG is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson\u2019s disease. Exp Neurol 273:36\u201344","journal-title":"Exp Neurol"},{"issue":"12","key":"457_CR35","doi-asserted-by":"publisher","first-page":"2021","DOI":"10.1016\/j.neurobiolaging.2008.02.009","volume":"30","author":"A Nadjar","year":"2009","unstructured":"Nadjar A et al (2009) IGF-1 signaling reduces neuro-inflammatory response and sensitivity of neurons to MPTP. Neurobiol Aging 30(12):2021\u20132030","journal-title":"Neurobiol Aging"},{"issue":"5","key":"457_CR36","doi-asserted-by":"publisher","first-page":"1794","DOI":"10.1007\/s10753-017-0623-4","volume":"40","author":"H Najafi","year":"2017","unstructured":"Najafi H, Yarijani ZM, Najafi M (2017) Theoretical and experimental in vivo study of antioxidant activity of crocin in order to propose novel derivatives with higher antioxidant activity and their delivery via nanotubes and nanocones. Inflammation 40(5):1794\u20131802","journal-title":"Inflammation"},{"issue":"1\u20133","key":"457_CR37","doi-asserted-by":"publisher","first-page":"110","DOI":"10.1016\/j.ejphar.2010.09.003","volume":"648","author":"KN Nam","year":"2010","unstructured":"Nam KN et al (2010) Anti-inflammatory effects of crocin and crocetin in rat brain microglial cells. Eur J Pharmacol 648(1\u20133):110\u2013116","journal-title":"Eur J Pharmacol"},{"key":"457_CR38","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1016\/j.neuint.2017.08.003","volume":"110","author":"N Pasquarelli","year":"2017","unstructured":"Pasquarelli N et al (2017) Contrasting effects of selective MAGL and FAAH inhibition on dopamine depletion and GDNF expression in a chronic MPTP mouse model of Parkinson\u2019s disease. Neurochem Int 110:14\u201324","journal-title":"Neurochem Int"},{"issue":"7","key":"457_CR39","doi-asserted-by":"publisher","first-page":"5055","DOI":"10.1074\/jbc.M110.178905","volume":"286","author":"HY Qureshi","year":"2011","unstructured":"Qureshi HY, Paudel HK (2011) Parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and \u03b1-synuclein mutations promote Tau protein phosphorylation at Ser262 and destabilize microtubule cytoskeleton in vitro. J Biol Chem 286(7):5055\u20135068","journal-title":"J Biol Chem"},{"issue":"1","key":"457_CR40","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1186\/1423-0127-19-56","volume":"19","author":"A Rajabzadeh","year":"2012","unstructured":"Rajabzadeh A et al (2012) The effect of PTZ-induced epileptic seizures on hippocampal expression of PSA-NCAM in offspring born to kindled rats. J Biomed Sci 19(1):56","journal-title":"J Biomed Sci"},{"issue":"1\u20132","key":"457_CR41","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/j.etp.2011.06.008","volume":"65","author":"T Sai","year":"2013","unstructured":"Sai T, Uchida K, Nakayama H (2013) Acute toxicity of MPTP and MPP\u2009+\u2009in the brain of embryo and newborn mice. Exp Toxicol Pathol 65(1\u20132):113\u2013119","journal-title":"Exp Toxicol Pathol"},{"issue":"11","key":"457_CR42","first-page":"895","volume":"17","author":"JR Sarshoori","year":"2014","unstructured":"Sarshoori JR, Asadi MH, Mohammadi MT (2014) Neuroprotective effects of crocin on the histopathological alterations following brain ischemia-reperfusion injury in rat. Iran J Basic Med Sci 17(11):895\u2013902","journal-title":"Iran J Basic Med Sci"},{"issue":"7","key":"457_CR43","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.4103\/1673-5374.211194","volume":"12","author":"S Singh","year":"2017","unstructured":"Singh S, Jamwal S, Kumar P (2017) Neuroprotective potential of Quercetin in combination with piperine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. Neural Regen Res 12(7):1137\u20131144","journal-title":"Neural Regen Res"},{"issue":"25","key":"457_CR44","doi-asserted-by":"publisher","first-page":"8557","DOI":"10.1523\/JNEUROSCI.0589-14.2014","volume":"34","author":"C Straub","year":"2014","unstructured":"Straub C et al (2014) Multiphasic modulation of cholinergic interneurons by nigrostriatal afferents. J Neurosci 34(25):8557\u20138569","journal-title":"J Neurosci"},{"key":"457_CR45","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.pneurobio.2013.04.004","volume":"106","author":"SR Subramaniam","year":"2013","unstructured":"Subramaniam SR, Chesselet M-F (2013) Mitochondrial dysfunction and oxidative stress in Parkinson\u2019s disease. Prog Neurobiol 106:17\u201332","journal-title":"Prog Neurobiol"},{"issue":"18","key":"457_CR46","first-page":"3439","volume":"41","author":"R Tunje","year":"2016","unstructured":"Tunje R et al (2016) Effect of Shouwu Shudi Yin on dopaminegic neurons in MPTP-induced Parkinson\u2019s disease mouse model (in Chinese). Zhongguo Zhong Yao Za Zhi 41(18):3439\u20133442","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"6","key":"457_CR47","first-page":"5569","volume":"14","author":"L Xia","year":"2017","unstructured":"Xia L, Guo D, Chen B (2017) Neuroprotective effects of astragaloside IV on Parkinson disease models of mice and primary astrocytes. Exp Ther Med 14(6):5569\u20135575","journal-title":"Exp Ther Med"},{"key":"457_CR48","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1016\/j.ejphar.2016.08.011","volume":"791","author":"L Xiao-feng","year":"2016","unstructured":"Xiao-feng L et al (2016) Protective role of 6-hydroxy-1-H-indazole in an MPTP-induced mouse model of Parkinson\u2019s disease. Eur J Pharmacol 791:348\u2013354","journal-title":"Eur J Pharmacol"},{"issue":"4","key":"457_CR49","doi-asserted-by":"publisher","first-page":"1019","DOI":"10.1016\/j.bbrc.2017.12.149","volume":"496","author":"W Yan","year":"2018","unstructured":"Yan W et al (2018) LncRNA NEAT1 promotes autophagy in MPTP-induced Parkinson\u2019s disease through stabilizing PINK1 protein. Biochem Biophys Res Commun 496(4):1019\u20131024","journal-title":"Biochem Biophys Res Commun"},{"issue":"2","key":"457_CR50","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/j.biocel.2012.11.015","volume":"45","author":"X Zhang","year":"2013","unstructured":"Zhang X et al (2013) Acetylcholinesterase deficiency decreases apoptosis in dopaminergic neurons in the neurotoxin model of Parkinson\u2019s disease. Int J Biochem Cell Biol 45(2):265\u2013272","journal-title":"Int J Biochem Cell Biol"},{"key":"457_CR51","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.neuropharm.2017.12.012","volume":"131","author":"Y-L Zhang","year":"2018","unstructured":"Zhang Y-L et al (2018) Ginsenoside Rb1 confers neuroprotection via promotion of glutamate transporters in a mouse model of Parkinson\u2019s disease. Neuropharmacology 131:223\u2013237","journal-title":"Neuropharmacology"}],"container-title":["Anatomical Science International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12565-018-0457-7\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12565-018-0457-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12565-018-0457-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,6]],"date-time":"2025-07-06T17:36:09Z","timestamp":1751823369000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12565-018-0457-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8,29]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["457"],"URL":"https:\/\/doi.org\/10.1007\/s12565-018-0457-7","relation":{},"ISSN":["1447-6959","1447-073X"],"issn-type":[{"value":"1447-6959","type":"print"},{"value":"1447-073X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,8,29]]},"assertion":[{"value":"16 May 2018","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"16 August 2018","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 August 2018","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with ethical standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}