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Both organ systems contain sensation devices necessary for visual perception and sexual intercourse. Their terminal structures are covered with eyelid\/prepuce followed by the sensitive epithelia of cornea\/glans facing the eyeball and glans. These structures have been closely studied in humans for appropriate visual perception and copulation and have thus been treated by numerous surgeries for long periods. Despite the vastly divergent anatomy and physiological functions, there are a few intriguing topohistological similarities for both structures, functions, and pathology. The current article focuses on such features from various viewpoints.<\/jats:p>","DOI":"10.1007\/s12565-025-00844-3","type":"journal-article","created":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T05:28:10Z","timestamp":1747114090000},"page":"1-5","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Topohistological alignments of ocular\/penile organs"],"prefix":"10.1007","volume":"101","author":[{"given":"Gen","family":"Yamada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daiki","family":"Hashimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kota","family":"Fujimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masanori","family":"Nakata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichi","family":"Asamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuhiko","family":"Kawakami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Lwigale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2025,5,13]]},"reference":[{"issue":"2","key":"844_CR1","doi-asserted-by":"publisher","first-page":"201","DOI":"10.1038\/s41443-019-0138-7","volume":"32","author":"T Antoniassi","year":"2020","unstructured":"Antoniassi T, J\u00fanior FNF, Spessoto LCF, Guerra LH, Campos SS, Taboga S (2020) Anti-fibrotic effect of mycophenolate mofetil on Peyronie\u2019s disease experimentally induced with TGF-\u03b2. 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