{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:59:07Z","timestamp":1787241547504,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,6,26]],"date-time":"2014-06-26T00:00:00Z","timestamp":1403740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of Physiological Sciences"],"published-print":{"date-parts":[[2015,1]]},"DOI":"10.1007\/s12576-014-0324-9","type":"journal-article","created":{"date-parts":[[2014,6,25]],"date-time":"2014-06-25T09:04:59Z","timestamp":1403687099000},"page":"1-9","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Autonomic nervous regulation of ovarian function by noxious somatic afferent stimulation"],"prefix":"10.1016","volume":"65","author":[{"given":"Sae","family":"Uchida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fusako","family":"Kagitani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl 1","key":"10.1007\/s12576-014-0324-9_bb0010","doi-asserted-by":"crossref","first-page":"9","DOI":"10.3109\/09513590.2012.651929","article-title":"Neuroendocrine control of ovulation","volume":"28","author":"Berga","year":"2012","journal-title":"Gynecol Endocrinol"},{"key":"10.1007\/s12576-014-0324-9_bb0015","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1055\/s-0032-1306301","article-title":"Hormonal regulation of female reproduction","volume":"44","author":"Christensen","year":"2012","journal-title":"Horm Metab Res"},{"key":"10.1007\/s12576-014-0324-9_bb0020","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/ar.1092070410","article-title":"The sensory innervation of the ovary: a horseradish peroxidase study in the rat","volume":"207","author":"Burden","year":"1983","journal-title":"Anat Rec"},{"key":"10.1007\/s12576-014-0324-9_bb0025","first-page":"261","article-title":"The adrenergic innervation of mammalian ovaries","author":"Burden","year":"1985"},{"key":"10.1007\/s12576-014-0324-9_bb0030","first-page":"445","article-title":"Origin, distribution, and functional aspects of aminergic and peptidergic nerves in the male and female reproductive tracts","author":"Owman","year":"1988"},{"key":"10.1007\/s12576-014-0324-9_bb0035","first-page":"103","article-title":"Autonomic efferent and visceral sensory innervation of the female reproductive system: special reference to the functional roles of nerves in reproductive organs","author":"Traurig","year":"1993"},{"key":"10.1007\/s12576-014-0324-9_bb0040","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1159\/000054372","article-title":"Neuronal labeling in the rat brain and spinal cord from the ovary using viral transneuronal tracing technique","volume":"68","author":"Gerendai","year":"1998","journal-title":"Neuroendocrinol"},{"key":"10.1007\/s12576-014-0324-9_bb0045","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0165-1838(00)00071-0","article-title":"CNS structures presumably involved in vagal control of ovarian function","volume":"80","author":"Gerendai","year":"2000","journal-title":"J Auton Nerv Syst"},{"key":"10.1007\/s12576-014-0324-9_bb0050","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1152\/physrev.1973.53.4.916","article-title":"Somatosympathetic reflexes: afferent fibers, central pathways, discharge characteristics","volume":"53","author":"Sato","year":"1973","journal-title":"Physiol Rev"},{"key":"10.1007\/s12576-014-0324-9_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BFb0046598","article-title":"The impact of somatosensory input on autonomic functions","volume":"130","author":"Sato","year":"1997","journal-title":"Rev Physiol Biochem Pharmacol"},{"key":"10.1007\/s12576-014-0324-9_bb0060","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/0168-0102(95)00907-B","article-title":"Somatocardiovascular reflexes in anesthetized rats with the central nervous system intact or acutely spinalized at the cervical level","volume":"22","author":"Kimura","year":"1995","journal-title":"Neurosci Res"},{"key":"10.1007\/s12576-014-0324-9_bb0065","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0306-4522(84)90154-4","article-title":"Responses of adrenal sympathetic nerve activity and catecholamine secretion to cutaneous stimulation in anesthetized rats","volume":"12","author":"Araki","year":"1984","journal-title":"Neurosci"},{"key":"10.1007\/s12576-014-0324-9_bb0070","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1152\/jn.1988.59.1.142","article-title":"Afferent fibers supplying the uterus in the rat","volume":"59","author":"Berkley","year":"1988","journal-title":"J Neurophysiol"},{"key":"10.1007\/s12576-014-0324-9_bb0075","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1152\/jn.1990.63.2.256","article-title":"Functional properties of afferent fibers supplying reproductive and other pelvic organs in pelvic nerve of female rat","volume":"63","author":"Berkley","year":"1990","journal-title":"J Neurophysiol"},{"key":"10.1007\/s12576-014-0324-9_bb0080","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/0304-3940(90)90791-7","article-title":"Responses of hypogastric nerve afferent fibers to uterine distension in estrous or metestrous rats","volume":"110","author":"Robbins","year":"1990","journal-title":"Neurosci Lett"},{"key":"10.1007\/s12576-014-0324-9_bb0085","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1152\/jn.1993.69.2.533","article-title":"Functional differences between afferent fibers in the hypogastric and pelvic nerves innervating female reproductive organs in the rat","volume":"69","author":"Berkley","year":"1993","journal-title":"J Neurophysiol"},{"key":"10.1007\/s12576-014-0324-9_bb0090","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0165-1838(96)00019-7","article-title":"Sympathetic and parasympathetic regulation of the uterine blood flow and contraction in the rat","volume":"59","author":"Sato","year":"1996","journal-title":"J Auton Nerv Syst"},{"key":"10.1007\/s12576-014-0324-9_bb0095","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0165-1838(98)00170-2","article-title":"Uterine contractility and blood flow are reflexively regulated by cutaneous afferent stimulation in anesthetized rats","volume":"75","author":"Hotta","year":"1999","journal-title":"J Auton Nerv Syst"},{"key":"10.1007\/s12576-014-0324-9_bb0100","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S1566-0702(03)00073-0","article-title":"Ovarian blood flow is reflexively regulated by mechanical afferent stimulation of a hindlimb in nonpregnant anesthetized rats","volume":"106","author":"Uchida","year":"2003","journal-title":"Auton Neurosci"},{"key":"10.1007\/s12576-014-0324-9_bb0105","doi-asserted-by":"crossref","first-page":"265","DOI":"10.2170\/jjphysiol.R2133","article-title":"Cutaneous mechanical stimulation regulates ovarian blood flow via activation of spinal and supraspinal reflex pathways in anesthetized rats","volume":"55","author":"Uchida","year":"2005","journal-title":"Jpn J Physiol"},{"key":"10.1007\/s12576-014-0324-9_bb0110","first-page":"410","article-title":"Responses of ovarian arterioles and ovarian blood flow to noradrenaline in rats","volume":"43","author":"Kanai","year":"2006","journal-title":"Autonomic Nerv Sys"},{"key":"10.1007\/s12576-014-0324-9_bb0115","doi-asserted-by":"crossref","first-page":"227","DOI":"10.2170\/physiolsci.RP003507","article-title":"Effects of thermal stimulation, applied to the hindpaw via a hot water bath, upon ovarian blood flow in anesthetized nonpregnant rats","volume":"57","author":"Uchida","year":"2007","journal-title":"J Physiol Sci"},{"key":"10.1007\/s12576-014-0324-9_bb0120","doi-asserted-by":"crossref","first-page":"133","DOI":"10.2170\/physiolsci.RP001508","article-title":"Effects of electrical stimulation of the superior ovarian nerve and the ovarian plexus nerve on the ovarian estradiol secretion rate in rats","volume":"58","author":"Kagitani","year":"2008","journal-title":"J Physiol Sci"},{"key":"10.1007\/s12576-014-0324-9_bb0125","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.autneu.2011.05.001","article-title":"Number, size, conduction, and vasoconstrictor ability of unmyelinated fibers of the ovarian nerve in adult and aged rats","volume":"164","author":"Hanada","year":"2011","journal-title":"Auton Neurosci"},{"key":"10.1007\/s12576-014-0324-9_bb0130","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s12576-011-0135-1","article-title":"The role of alpha adrenoceptors in the vascular and estradiol secretory responses to stimulation of the superior ovarian nerve","volume":"61","author":"Kagitani","year":"2011","journal-title":"J Physiol Sci"},{"issue":"suppl 1","key":"10.1007\/s12576-014-0324-9_bb0135","first-page":"S215","article-title":"Effects of ovarian sympathetic nerve stimulation on ovarian testosterone secretion in rats","volume":"63","author":"Kagitani","year":"2013","journal-title":"J Physiol Sci"},{"key":"10.1007\/s12576-014-0324-9_bb0140","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.autneu.2013.10.007","article-title":"Effects of electrical stimulation of autonomic nerves to the ovary on the ovarian testosterone secretion rate in rats","volume":"180","author":"Uchida","year":"2014","journal-title":"Auton Neurosci"},{"key":"10.1007\/s12576-014-0324-9_bb0145","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.autneu.2012.08.014","article-title":"Reflex modulation of ovarian estradiol secretion by noxious mechanical stimulation of a hindpaw in anesthetized rats","volume":"171","author":"Uchida","year":"2012","journal-title":"Auton Neurosci"},{"key":"10.1007\/s12576-014-0324-9_bb0150","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/ar.1091960106","article-title":"The origin of the extrinsic adrenergic innervation to the rat ovary","volume":"196","author":"Lawrence","year":"1980","journal-title":"Anat Rec"},{"key":"10.1007\/s12576-014-0324-9_bb0155","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000145073","article-title":"The extrinsic innervation of the abdominal organs in the female rat","volume":"104","author":"Baljet","year":"1979","journal-title":"Acta Anat (Basel)"},{"key":"10.1007\/s12576-014-0324-9_bb0160","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/aja.1001330407","article-title":"Adrenergic innervation in ovaries of the rat and guinea pig","volume":"133","author":"Burden","year":"1972","journal-title":"Am J Anat"},{"key":"10.1007\/s12576-014-0324-9_bb0165","author":"Greene","year":"1963"},{"key":"10.1007\/s12576-014-0324-9_bb0170","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1093\/humrep\/15.2.264","article-title":"Evidence for the involvement of blood flow-related mechanisms in the ovulatory process of the rat","volume":"15","author":"Zackrisson","year":"2000","journal-title":"Hum Reprod"},{"key":"10.1007\/s12576-014-0324-9_bb0175","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1679\/aohc.51.299","article-title":"The blood vascular wreath of rat ovarian follicle, with special reference to its changes in ovulation and luteinization: a scanning electron microscopic study of corrosion casts","volume":"51","author":"Murakami","year":"1988","journal-title":"Arch Histol Cytol"},{"key":"10.1007\/s12576-014-0324-9_bb0180","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1530\/jrf.0.0710065","article-title":"Contractility of the ovarian vascular bed during the oestrous cycle and early pregnancy in gilts","volume":"71","author":"Reynolds","year":"1984","journal-title":"J Reprod Fert"},{"key":"10.1007\/s12576-014-0324-9_bb0185","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1159\/000299921","article-title":"Stimulation of the alpha- and beta-adrenergic receptors in human ovarian vasculature in vitro","volume":"10","author":"Varga","year":"1979","journal-title":"Gynecol Obstet Invest"},{"key":"10.1007\/s12576-014-0324-9_bb0190","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1530\/jrf.0.0750351","article-title":"Acute increase of noradrenaline on vascular resistance in the corpus luteum of the pseudopregnant rat","volume":"75","author":"Selstam","year":"1985","journal-title":"J Reprod Fert"},{"key":"10.1007\/s12576-014-0324-9_bb0195","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1530\/jrf.0.1010605","article-title":"Effects of noradrenaline on blood flow, progesterone secretion and oxygen consumption in the intact ovary of rats on day 16 of pregnancy","volume":"101","author":"Massa","year":"1994","journal-title":"J Reprod Fert"},{"key":"10.1007\/s12576-014-0324-9_bb0200","first-page":"3","article-title":"Organization of the endocrine system","author":"Ojeda","year":"2012"},{"key":"10.1007\/s12576-014-0324-9_bb0205","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0303-7207(94)90278-X","article-title":"Follicular oestrogen synthesis: the \u2018two-cell, two-gonadotrophin\u2019 model revisited","volume":"100","author":"Hillier","year":"1994","journal-title":"Mol Cell Endocrinol"},{"key":"10.1007\/s12576-014-0324-9_bb0210","first-page":"194","article-title":"Female reproductive function","author":"Ojeda","year":"2012"},{"key":"10.1007\/s12576-014-0324-9_bb0215","first-page":"231","article-title":"Neuroendocrine components in the regulation of renin secretion","author":"Ganong","year":"1982"},{"key":"10.1007\/s12576-014-0324-9_bb0220","unstructured":"Reiter RJ (1982) Neuroendocrine effects of the pineal gland and of melatonin. In: Ganong WF, Martini L (eds) Frontiers in Neuroendocrinology, Raven Press, vol 7. New York, pp 287-316"},{"key":"10.1007\/s12576-014-0324-9_bb0225","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1172\/JCI107168","article-title":"Neural regulation of insulin secretion in the dog","volume":"52","author":"Porte","year":"1973","journal-title":"J Clin Invest"},{"key":"10.1007\/s12576-014-0324-9_bb0230","doi-asserted-by":"crossref","first-page":"554","DOI":"10.2337\/diab.27.5.554","article-title":"Induction of defective insulin secretion and impaired glucose tolerance by clonidine. Selective stimulation of metabolic alpha-adrenergic pathways","volume":"27","author":"Metz","year":"1978","journal-title":"Diabetes"},{"key":"10.1007\/s12576-014-0324-9_bb0235","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1016\/S0022-3565(25)32473-0","article-title":"Postsynaptic alpha-2 adrenergic receptors in isolated rat islets of Langerhans: inhibition of insulin release and cyclic 3\u2032:5\u2032-adenosine monophosphate accumulation","volume":"216","author":"Nakaki","year":"1981","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1007\/s12576-014-0324-9_bb0240","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1210\/endo.133.6.7902268","article-title":"Activation of ovarian sympathetic nerves in polycystic ovary syndrome","volume":"133","author":"Lara","year":"1993","journal-title":"Endocrinology"},{"key":"10.1007\/s12576-014-0324-9_bb0245","doi-asserted-by":"crossref","first-page":"E576","DOI":"10.1152\/ajpendo.00725.2007","article-title":"Is polycystic ovary syndrome associated with high sympathetic nerve activity and size at birth?","volume":"294","author":"Sverrisd\u00f3ttir","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"}],"container-title":["The Journal of Physiological Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12576-014-0324-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12576-014-0324-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S188065462400831X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S188065462400831X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12576-014-0324-9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12576-014-0324-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,12]],"date-time":"2025-04-12T17:42:28Z","timestamp":1744479748000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S188065462400831X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1]]},"references-count":48,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["S188065462400831X"],"URL":"https:\/\/doi.org\/10.1007\/s12576-014-0324-9","relation":{},"ISSN":["1880-6546"],"issn-type":[{"value":"1880-6546","type":"print"}],"subject":[],"published":{"date-parts":[[2015,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autonomic nervous regulation of ovarian function by noxious somatic afferent stimulation","name":"articletitle","label":"Article Title"},{"value":"The Journal of Physiological Sciences","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s12576-014-0324-9","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 \u00a9 The Author(s) 2014. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}