{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:19:17Z","timestamp":1761808757381,"version":"build-2065373602"},"reference-count":32,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T00:00:00Z","timestamp":1719532800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100006769","name":"Russian Science Foundation","doi-asserted-by":"crossref","award":["22-25-00401","22-25-00401"],"award-info":[{"award-number":["22-25-00401","22-25-00401"]}],"id":[{"id":"10.13039\/501100006769","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics & Antimicro. Prot."],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1007\/s12602-024-10317-0","type":"journal-article","created":{"date-parts":[[2024,6,28]],"date-time":"2024-06-28T08:02:35Z","timestamp":1719561755000},"page":"3538-3545","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lactobacilli Have an Opposite Effect on the Resistance to Oxidative Damage of HPV-Infected Compared with Uninfected Vaginal Epithelial Cells"],"prefix":"10.1007","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1866-1678","authenticated-orcid":false,"given":"Andrey","family":"Sgibnev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1916-784X","authenticated-orcid":false,"given":"Elena","family":"Kremleva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2024,6,28]]},"reference":[{"issue":"3","key":"10317_CR1","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.fertnstert.2018.06.036","volume":"110","author":"SJ Kroon","year":"2018","unstructured":"Kroon SJ, Ravel J, Huston WM (2018) Cervicovaginal microbiota, women\u2019s health, and reproductive outcomes. Fertil Steril 110(3):327\u2013336. https:\/\/doi.org\/10.1016\/j.fertnstert.2018.06.036","journal-title":"Fertil Steril"},{"issue":"4","key":"10317_CR2","doi-asserted-by":"publisher","first-page":"643","DOI":"10.1097\/AOG.0000000000001932","volume":"129","author":"FMT Lewis","year":"2017","unstructured":"Lewis FMT, Bernstein KT, Aral SO (2017) Vaginal microbiome and its relationship to behavior, sexual health, and sexually transmitted diseases. Obstet Gynecol 129(4):643\u2013654. https:\/\/doi.org\/10.1097\/AOG.0000000000001932","journal-title":"Obstet Gynecol"},{"issue":"9\u201310","key":"10317_CR3","doi-asserted-by":"publisher","first-page":"859","DOI":"10.1016\/j.resmic.2017.02.003","volume":"168","author":"JHHM van de Wijgert","year":"2017","unstructured":"van de Wijgert JHHM, Jespers V (2017) The global health impact of vaginal dysbiosis. Res Microbiol 168(9\u201310):859\u2013864. https:\/\/doi.org\/10.1016\/j.resmic.2017.02.003","journal-title":"Res Microbiol"},{"issue":"2","key":"10317_CR4","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1067\/mob.2001.115867","volume":"185","author":"A Aroutcheva","year":"2001","unstructured":"Aroutcheva A, Gariti D, Simon M, Shott S, Faro J, Simoes JA, Gurguis A, Faro S (2001) Defense factors of vaginal lactobacilli. Am J Obstet Gynecol 185(2):375\u2013379. https:\/\/doi.org\/10.1067\/mob.2001.115867","journal-title":"Am J Obstet Gynecol"},{"key":"10317_CR5","doi-asserted-by":"publisher","first-page":"164","DOI":"10.3389\/fphys.2015.00164","volume":"6","author":"M Aldunate","year":"2015","unstructured":"Aldunate M, Srbinovski D, Hearps AC, Latham CF, Ramsland PA, Gugasyan R, Cone RA, Tachedjian G (2015) Antimicrobial and immune modulatory effects of lactic acid and short chain fatty acids produced by vaginal microbiota associated with eubiosis and bacterial vaginosis. Front Physiol 6:164. https:\/\/doi.org\/10.3389\/fphys.2015.00164","journal-title":"Front Physiol"},{"issue":"5","key":"10317_CR6","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1016\/j.immuni.2015.04.019","volume":"42","author":"MN Anahtar","year":"2015","unstructured":"Anahtar MN, Byrne EH, Doherty KE, Bowman BA, Yamamoto HS, Soumillon M, Padavattan N, Ismail N, Moodley A, Sabatini ME, Ghebremichael MS, Nusbaum C, Huttenhower C, Virgin HW, Ndung\u2019u T, Dong KL, Walker BD, Fichorova RN, Kwon DS, (2015) Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract. Immunity 42(5):965\u2013976. https:\/\/doi.org\/10.1016\/j.immuni.2015.04.019","journal-title":"Immunity"},{"issue":"3","key":"10317_CR7","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1007\/s00404-013-3064-9","volume":"289","author":"S Borges","year":"2014","unstructured":"Borges S, Silva J, Teixeira P (2014) The role of lactobacilli and probiotics in maintaining vaginal health. Arch Gynecol Obstet 289(3):479\u2013489. https:\/\/doi.org\/10.1007\/s00404-013-3064-9","journal-title":"Arch Gynecol Obstet"},{"issue":"10","key":"10317_CR8","doi-asserted-by":"publisher","DOI":"10.5812\/jjm.22913","volume":"8","author":"A Sgibnev","year":"2015","unstructured":"Sgibnev A, Kremleva E (2015) Vaginal protection by H2O2-producing lactobacilli. Jundishapur J Microbiol 8(10):e22913. https:\/\/doi.org\/10.5812\/jjm.22913","journal-title":"Jundishapur J Microbiol"},{"key":"10317_CR9","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s12602-016-9238-6","volume":"9","author":"A Sgibnev","year":"2017","unstructured":"Sgibnev A, Kremleva E (2017) Influence of hydrogen peroxide, lactic acid, and surfactants from vaginal lactobacilli on the antibiotic sensitivity of opportunistic bacteria. Probiotics & Antimicro Prot 9:131\u2013141. https:\/\/doi.org\/10.1007\/s12602-016-9238-6","journal-title":"Probiotics & Antimicro Prot"},{"issue":"1","key":"10317_CR10","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1186\/s40168-016-0203-0","volume":"4","author":"A Mitra","year":"2016","unstructured":"Mitra A, MacIntyre DA, Marchesi JR, Lee YS, Bennett PR, Kyrgiou M (2016) The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next? Microbiome 4(1):58. https:\/\/doi.org\/10.1186\/s40168-016-0203-0","journal-title":"Microbiome"},{"issue":"2","key":"10317_CR11","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1111\/1471-0528.15981","volume":"127","author":"JC Borgogna","year":"2020","unstructured":"Borgogna JC, Shardell MD, Santori EK, Nelson TM, Rath JM, Glover ED, Ravel J, Gravitt PE, Yeoman CJ, Brotman RM (2020) The vaginal metabolome and microbiota of cervical HPV-positive and HPV-negative women: a cross-sectional analysis. BJOG 127(2):182\u2013192. https:\/\/doi.org\/10.1111\/1471-0528.15981","journal-title":"BJOG"},{"issue":"2","key":"10317_CR12","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1111\/1471-0528.15854","volume":"127","author":"J Norenhag","year":"2020","unstructured":"Norenhag J, Du J, Olovsson M, Verstraelen H, Engstrand L, Brusselaers N (2020) The vaginal microbiota, human papillomavirus and cervical dysplasia: a systematic review and network meta-analysis. BJOG 127(2):171\u2013180. https:\/\/doi.org\/10.1111\/1471-0528.15854","journal-title":"BJOG"},{"issue":"6","key":"10317_CR13","doi-asserted-by":"publisher","first-page":"1863","DOI":"10.1086\/315127","volume":"180","author":"HL Martin","year":"1999","unstructured":"Martin HL, Richardson BA, Nyange PM, Lavreys L, Hillier SL, Chohan B, Mandaliya K, Ndinya-Achola JO, Bwayo J, Kreiss J (1999) Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisition. J Infect Dis 180(6):1863\u20131868. https:\/\/doi.org\/10.1086\/315127","journal-title":"J Infect Dis"},{"key":"10317_CR14","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.596166","volume":"10","author":"A Harper","year":"2021","unstructured":"Harper A, Vijayakumar V, Ouwehand AC, Ter Haar J, Obis D, Espadaler J, Binda S, Desiraju S, Day R (2021) Viral infections, the microbiome, and probiotics. Front Cell Infect Microbiol 10:596166. https:\/\/doi.org\/10.3389\/fcimb.2020.596166","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"10317_CR15","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1186\/s12879-017-2938-z","volume":"18","author":"E Palma","year":"2018","unstructured":"Palma E, Recine N, Domenici L, Giorgini M, Pierangeli A, Panici PB (2018) Long-term Lactobacillus rhamnosus BMX 54 application to restore a balanced vaginal ecosystem: a promising solution against HPV-infection. BMC Infect Dis 18(1):13. https:\/\/doi.org\/10.1186\/s12879-017-2938-z","journal-title":"BMC Infect Dis"},{"issue":"2","key":"10317_CR16","doi-asserted-by":"publisher","first-page":"273","DOI":"10.1016\/j.molcel.2014.01.027","volume":"54","author":"JW Upton","year":"2014","unstructured":"Upton JW, Chan FK (2014) Staying alive: cell death in antiviral immunity. Mol Cell 54(2):273\u2013280. https:\/\/doi.org\/10.1016\/j.molcel.2014.01.027","journal-title":"Mol Cell"},{"key":"10317_CR17","doi-asserted-by":"publisher","first-page":"367","DOI":"10.3389\/fcimb.2017.00367","volume":"7","author":"G Canedo-Marroqu\u00edn","year":"2017","unstructured":"Canedo-Marroqu\u00edn G, Acevedo-Acevedo O, Rey-Jurado E, Saavedra JM, Lay MK, Bueno SM, Riedel CA, Kalergis AM (2017) Modulation of host immunity by human respiratory syncytial virus virulence factors: a synergic inhibition of both innate and adaptive immunity. Front Cell Infect Microbiol 7:367. https:\/\/doi.org\/10.3389\/fcimb.2017.00367","journal-title":"Front Cell Infect Microbiol"},{"issue":"1","key":"10317_CR18","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1189\/jlb.0705397","volume":"79","author":"A Iannello","year":"2006","unstructured":"Iannello A, Debbeche O, Martin E, Attalah LH, Samarani S, Ahmad A (2006) Viral strategies for evading antiviral cellular immune responses of the host. J Leukoc Biol 79(1):16\u201335. https:\/\/doi.org\/10.1189\/jlb.0705397","journal-title":"J Leukoc Biol"},{"key":"10317_CR19","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.mcp.2016.11.006","volume":"32","author":"VV Demkin","year":"2017","unstructured":"Demkin VV, Koshechkin SI, Slesarev A (2017) A novel real-time PCR assay for highly specific detection and quantification of vaginal lactobacilli. Mol Cell Probes 32:33\u201339. https:\/\/doi.org\/10.1016\/j.mcp.2016.11.006","journal-title":"Mol Cell Probes"},{"key":"10317_CR20","doi-asserted-by":"publisher","first-page":"81","DOI":"10.3389\/fphys.2015.00081","volume":"6","author":"MI Petrova","year":"2015","unstructured":"Petrova MI, Lievens E, Malik S, Imholz N, Lebeer S (2015) Lactobacillus species as biomarkers and agents that can promote various aspects of vaginal health. Front Physiol 6:81. https:\/\/doi.org\/10.3389\/fphys.2015.00081","journal-title":"Front Physiol"},{"issue":"sup1","key":"10317_CR21","doi-asserted-by":"publisher","first-page":"877","DOI":"10.1080\/13102818.2009.10818562","volume":"23","author":"E Shikova","year":"2009","unstructured":"Shikova E, Todorova I, Ganchev G, Kouseva-Dragneva V (2009) Detection and typing of human papillomaviruses by PCR. Biotechnol Biotechnol Equip 23(sup1):877\u2013880. https:\/\/doi.org\/10.1080\/13102818.2009.10818562","journal-title":"Biotechnol Biotechnol Equip"},{"issue":"1","key":"10317_CR22","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1134\/s0006297906010093","volume":"71","author":"OY Pletjushkina","year":"2006","unstructured":"Pletjushkina OY, Fetisova EK, Lyamzaev KG, Ivanova OY, Domnina LV, Vyssokikh MY, Pustovidko AV, Alexeevski AV, Alexeevski DA, Vasiliev JM, Murphy MP, Chernyak BV, Skulachev VP (2006) Hydrogen peroxide produced inside mitochondria takes part in cell-to-cell transmission of apoptotic signal. Biochemistry (Mosc) 71(1):60\u201367. https:\/\/doi.org\/10.1134\/s0006297906010093","journal-title":"Biochemistry (Mosc)"},{"issue":"7","key":"10317_CR23","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S1473-3099(07)70158-5","volume":"7","author":"S de Sanjos\u00e9","year":"2007","unstructured":"de Sanjos\u00e9 S, Diaz M, Castellsagu\u00e9 X, Clifford G, Bruni L, Mu\u00f1oz N, Bosch FX (2007) Worldwide prevalence and genotype distribution of cervical human papillomavirus DNA in women with normal cytology: a meta-analysis. Lancet Infect Dis 7(7):453\u2013459. https:\/\/doi.org\/10.1016\/S1473-3099(07)70158-5","journal-title":"Lancet Infect Dis"},{"issue":"11","key":"10317_CR24","doi-asserted-by":"publisher","first-page":"660","DOI":"10.1097\/OLQ.0000000000000193","volume":"41","author":"HW Chesson","year":"2014","unstructured":"Chesson HW, Dunne EF, Hariri S, Markowitz LE (2014) The estimated lifetime probability of acquiring human papillomavirus in the United States. Sex Transm Dis 41(11):660\u2013664. https:\/\/doi.org\/10.1097\/OLQ.0000000000000193","journal-title":"Sex Transm Dis"},{"issue":"1","key":"10317_CR25","doi-asserted-by":"publisher","first-page":"130","DOI":"10.3390\/foods10010130","volume":"10","author":"A Lopez-Santamarina","year":"2021","unstructured":"Lopez-Santamarina A, Lamas A, Del Carmen MA, Cardelle-Cobas A, Regal P, Rodriguez-Avila JA, Miranda JM, Franco CM, Cepeda A (2021) Probiotic effects against virus infections: new weapons for an old war. Foods 10(1):130. https:\/\/doi.org\/10.3390\/foods10010130","journal-title":"Foods"},{"issue":"8","key":"10317_CR26","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1007\/s11912-021-01079-x","volume":"23","author":"LM Chambers","year":"2021","unstructured":"Chambers LM, Bussies P, Vargas R, Esakov E, Tewari S, Reizes O, Michener C (2021) The microbiome and gynecologic cancer: current evidence and future opportunities. Curr Oncol Rep 23(8):92. https:\/\/doi.org\/10.1007\/s11912-021-01079-x","journal-title":"Curr Oncol Rep"},{"issue":"1","key":"10317_CR27","doi-asserted-by":"publisher","first-page":"68","DOI":"10.1186\/s13048-020-00668-x","volume":"13","author":"M Jahanshahi","year":"2020","unstructured":"Jahanshahi M, Maleki Dana P, Badehnoosh B, Asemi Z, Hallajzadeh J, Mansournia MA, Yousefi B, Moazzami B, Chaichian S (2020) Anti-tumor activities of probiotics in cervical cancer. J Ovarian Res 13(1):68. https:\/\/doi.org\/10.1186\/s13048-020-00668-x","journal-title":"J Ovarian Res"},{"issue":"11","key":"10317_CR28","doi-asserted-by":"publisher","first-page":"800","DOI":"10.1016\/j.tcb.2017.05.007","volume":"27","author":"MH Orzalli","year":"2017","unstructured":"Orzalli MH, Kagan JC (2017) Apoptosis and necroptosis as host defense strategies to prevent viral infection. Trends Cell Biol 27(11):800\u2013809. https:\/\/doi.org\/10.1016\/j.tcb.2017.05.007","journal-title":"Trends Cell Biol"},{"issue":"1","key":"10317_CR29","doi-asserted-by":"publisher","first-page":"1978","DOI":"10.1038\/s41598-020-58862-2","volume":"10","author":"E Roselletti","year":"2020","unstructured":"Roselletti E, Sabbatini S, Perito S, Mencacci A, Vecchiarelli A, Monari C (2020) Apoptosis of vaginal epithelial cells in clinical samples from women with diagnosed bacterial vaginosis. Sci Rep 10(1):1978. https:\/\/doi.org\/10.1038\/s41598-020-58862-2","journal-title":"Sci Rep"},{"key":"10317_CR30","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1186\/1471-2334-12-33","volume":"12","author":"MA Clarke","year":"2012","unstructured":"Clarke MA, Rodriguez AC, Gage JC, Herrero R, Hildesheim A, Wacholder S, Burk R, Schiffman M (2012) A large, population-based study of age-related associations between vaginal pH and human papillomavirus infection. BMC Infect Dis 12:33. https:\/\/doi.org\/10.1186\/1471-2334-12-33","journal-title":"BMC Infect Dis"},{"key":"10317_CR31","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2022.863208","volume":"12","author":"D Pacha-Herrera","year":"2022","unstructured":"Pacha-Herrera D, Erazo-Garcia MP, Cueva DF, Orellana M, Borja-Serrano P, Arboleda C, Tejera E, Machado A (2022) Clustering analysis of the multi-microbial consortium by lactobacillus species against vaginal dysbiosis among ecuadorian women. Front Cell Infect Microbiol 12:863208. https:\/\/doi.org\/10.3389\/fcimb.2022.863208","journal-title":"Front Cell Infect Microbiol"},{"issue":"3","key":"10317_CR32","doi-asserted-by":"publisher","first-page":"636","DOI":"10.3390\/microorganisms11030636","volume":"11","author":"S Pendharkar","year":"2023","unstructured":"Pendharkar S, Skafte-Holm A, Simsek G, Haahr T (2023) Lactobacilli and their probiotic effects in the vagina of reproductive age women. Microorganisms 11(3):636. https:\/\/doi.org\/10.3390\/microorganisms11030636","journal-title":"Microorganisms"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-024-10317-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-024-10317-0\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-024-10317-0.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T13:05:44Z","timestamp":1760619944000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-024-10317-0"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":32,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["10317"],"URL":"https:\/\/doi.org\/10.1007\/s12602-024-10317-0","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"type":"print","value":"1867-1306"},{"type":"electronic","value":"1867-1314"}],"subject":[],"published":{"date-parts":[[2024,6,28]]},"assertion":[{"value":"23 June 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 June 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}