{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:27:29Z","timestamp":1791415649936,"version":"4.3.3"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T00:00:00Z","timestamp":1721001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics &amp; Antimicro. Prot."],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1007\/s12602-024-10321-4","type":"journal-article","created":{"date-parts":[[2024,7,15]],"date-time":"2024-07-15T01:01:22Z","timestamp":1721005282000},"page":"3887-3902","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Prophylactic Effect and Antiulcerogenic Potential of Probiotic Lactiplantibacillus plantarum E1K2R2 and its Exopolysaccharide Against Ibuprofen-Induced Acute Gastric Ulcer"],"prefix":"10.1007","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4417-0752","authenticated-orcid":false,"given":"Nadia","family":"Aliouche","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3849-6104","authenticated-orcid":false,"given":"Mohamed","family":"Sifour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1942-9500","authenticated-orcid":false,"given":"Widad","family":"Kebsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1992-4890","authenticated-orcid":false,"given":"Tarek","family":"Khennouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2339-5669","authenticated-orcid":false,"given":"Feriha","family":"Ercan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3880-7550","authenticated-orcid":false,"given":"Houria","family":"Ouled-Haddar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,7,15]]},"reference":[{"issue":"4","key":"10321_CR1","doi-asserted-by":"publisher","first-page":"1802","DOI":"10.13040\/IJPSR.0975-8232.11(4).1802-07","volume":"11","author":"P Kulkarni","year":"2020","unstructured":"Kulkarni P, Bhavimani G, Javalgikar A, Mahurkar N (2020) Evaluation of melatonin and coenzyme Q10 for gastroprotective effec t in aspirin and ibuprofen induced gastric ulcers in rats. Int J Pharm Sci Res 11(4):1802\u20131807. https:\/\/doi.org\/10.13040\/IJPSR.0975-8232.11(4).1802-07","journal-title":"Int J Pharm Sci Res"},{"key":"10321_CR2","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1016\/j.lfs.2018.08.035","volume":"209","author":"KRM Barboza","year":"2018","unstructured":"Barboza KRM, Coco LZ, Alves GM, Peters B, Vasquez EC, Pereira TMC, Campagnaro BP (2018) Gastroprotective effect of oral kefir on indomethacin-induced acute gastric lesions in mice: Impact on oxidative stress. Life Sci 209:370\u2013376. https:\/\/doi.org\/10.1016\/j.lfs.2018.08.035","journal-title":"Life Sci"},{"issue":"1","key":"10321_CR3","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s41936-018-0025-7","volume":"79","author":"S Gomaa","year":"2018","unstructured":"Gomaa S (2018) Adverse effects induced by diclofenac, ibuprofen, and paracetamol toxicity on immunological and biochemical parameters in Swiss albino mice. J Basic Appl Zool 79(1):1\u20139. https:\/\/doi.org\/10.1186\/s41936-018-0025-7","journal-title":"J Basic Appl Zool"},{"issue":"3","key":"10321_CR4","doi-asserted-by":"publisher","first-page":"074","DOI":"10.30574\/gscbps.2022.20.3.0347","volume":"20","author":"H Uslu","year":"2022","unstructured":"Uslu H, Uslu GA (2022) Gastroprotective effects of Taraxacum officinale (Dandelion) extract indomethacin-induced gastric ulcer model. GSC Biol Pharm Sci 20(3):074\u2013081. https:\/\/doi.org\/10.30574\/gscbps.2022.20.3.0347","journal-title":"GSC Biol Pharm Sci"},{"key":"10321_CR5","doi-asserted-by":"publisher","first-page":"114331","DOI":"10.1016\/j.biopha.2023.114331","volume":"160","author":"MF Mahmoud","year":"2023","unstructured":"Mahmoud MF, Abdo W, Nabil M, Drissi B, El-Shazly AM, Abdelfattah MA, Sobeh M (2023) Apple (Malus domestica Borkh) leaves attenuate indomethacin-induced gastric ulcer in rats. Biomed Pharmacother 160:114331. https:\/\/doi.org\/10.1016\/j.biopha.2023.114331","journal-title":"Biomed Pharmacother"},{"issue":"3","key":"10321_CR6","first-page":"433","volume":"8","author":"IZ Abdallah","year":"2011","unstructured":"Abdallah IZ, Khattab HA, Gehan HH (2011) Gastroprotective effect of Cordia myxa L. fruit extract against indomethacin-induced gastric ulceration in rats. Life Sci J 8(3):433\u2013445","journal-title":"Life Sci J"},{"issue":"2","key":"10321_CR7","doi-asserted-by":"publisher","first-page":"83","DOI":"10.47583\/ijpsrr.2022.v73i02.017","volume":"73","author":"HB Akpan","year":"2022","unstructured":"Akpan HB, Elijah SO, Amadi MA, Onyeleonu I, Enya JI, Fubara BT (2022) Ibuprofen-induced gastric ulcer in Wistar rats: Evaluating the impact of fermented ripe and unripe Carica papaya compared to omeprazole. Int J Pharm Sci Rev Res 73(2):83\u201391. https:\/\/doi.org\/10.47583\/ijpsrr.2022.v73i02.017","journal-title":"Int J Pharm Sci Rev Res"},{"issue":"16","key":"10321_CR8","doi-asserted-by":"publisher","first-page":"7250","DOI":"10.1039\/D1FO00181G","volume":"12","author":"R Yang","year":"2021","unstructured":"Yang R, Li J, Xu X, Xu K, Shi J (2021) Preventive and therapeutic effects of Lactobacillus rhamnosus SHA113 and its culture supernatant on alcoholic gastric ulcers. Food Funct 12(16):7250\u20137259. https:\/\/doi.org\/10.1039\/D1FO00181G","journal-title":"Food Funct"},{"issue":"9","key":"10321_CR9","doi-asserted-by":"publisher","first-page":"311","DOI":"10.4236\/jbm.2022.109022","volume":"10","author":"FA Ngwa","year":"2022","unstructured":"Ngwa FA, Fossi BT, Taiwe GS, Tatsinkou LLT, Bobga PT, Ndalloka MT, Wanji S (2022) Isolation, characterisation and evaluation of antiulcerogenic potentials of probiotic lactic acid bacteria isolated from fermented milk and palm wine against ethanol-induced gastric ulcer in mice. J Biosci Med 10(9):311\u2013331. https:\/\/doi.org\/10.4236\/jbm.2022.109022","journal-title":"J Biosci Med"},{"key":"10321_CR10","unstructured":"FAO\/WHO (2002) Guidelines for the Evaluation of Probiotics in Food. London, Ontario, Canada, 30"},{"key":"10321_CR11","doi-asserted-by":"publisher","first-page":"109722","DOI":"10.1016\/j.enzmictec.2020.109722","volume":"143","author":"M Moradi","year":"2021","unstructured":"Moradi M, Molaei R, Guimar\u00e3es JT (2021) A review on preparation and chemical analysis of postbiotics from lactic acid bacteria. Enzyme Microb Technol 143:109722. https:\/\/doi.org\/10.1016\/j.enzmictec.2020.109722","journal-title":"Enzyme Microb Technol"},{"key":"10321_CR12","doi-asserted-by":"publisher","first-page":"123845","DOI":"10.1016\/j.ijbiomac.2023.123845","volume":"235","author":"R Yang","year":"2023","unstructured":"Yang R, Li J, Jiang C, Shi J (2023) Preventive and therapeutic effects of an exopolysaccharide produced by Lacticaseibacillus rhamnosus on alcoholic gastric ulcers. Int J Biol Macromol 235:123845. https:\/\/doi.org\/10.1016\/j.ijbiomac.2023.123845","journal-title":"Int J Biol Macromol"},{"issue":"3","key":"10321_CR13","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1007\/s00217-012-1779-7","volume":"235","author":"W Li","year":"2012","unstructured":"Li W, Mutuvulla M, Chen X, Jiang M, Dong M (2012) Isolation and identification of high viscosity-producing lactic acid bacteria from a traditional fermented milk in Xinjiang and its role in fermentation process. Eur Food Res Technol 235(3):497\u2013505. https:\/\/doi.org\/10.1007\/s00217-012-1779-7","journal-title":"Eur Food Res Technol"},{"issue":"3","key":"10321_CR14","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1021\/ac60111a017","volume":"28","author":"M Dubois","year":"1956","unstructured":"Dubois M et al (1956) Colorimetric method for determination of sugars and related substances. Anal Chem 28(3):350\u2013356","journal-title":"Anal Chem"},{"key":"10321_CR15","doi-asserted-by":"publisher","first-page":"1615","DOI":"10.1007\/s42770-020-00302-4","volume":"51","author":"K Riane","year":"2020","unstructured":"Riane K, Sifour M, Ouled-Haddar H, Espinosa C, Esteban MA, Lahouel M (2020) Effect of probiotic supplementation on oxidative stress markers in rats with diclofenac-induced hepatotoxicity. Braz J Microbiol 51:1615\u20131622. https:\/\/doi.org\/10.1007\/s42770-020-00302-4","journal-title":"Braz J Microbiol"},{"key":"10321_CR16","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s13205-021-02784-x","volume":"11","author":"V Deepak","year":"2021","unstructured":"Deepak V, Sundar WA, Pandian SRK, Sivasubramaniam SD, Hariharan N, Sundar K (2021) Exopolysaccharides from Lactobacillus acidophilus modulates the antioxidant status of 1, 2\u2013dimethyl hydrazine-induced colon cancer rat model. 3 Biotech 11:1\u20139. https:\/\/doi.org\/10.1007\/s13205-021-02784-x","journal-title":"3 Biotech"},{"key":"10321_CR17","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.lfs.2016.02.045","volume":"149","author":"J Liu","year":"2016","unstructured":"Liu J, Sun D, He J, Yang C, Hu T, Zhang L, Zheng Y (2016) Gastroprotective effects of several H2RAs on ibuprofen-induced gastric ulcer in rats. Life Sci 149:65\u201371. https:\/\/doi.org\/10.1016\/j.lfs.2016.02.045","journal-title":"Life Sci"},{"issue":"1\u20132","key":"10321_CR18","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/j.jep.2004.09.007","volume":"96","author":"KB Ajaikumar","year":"2005","unstructured":"Ajaikumar KB, Asheef M, Babu BH, Padikkala J (2005) The inhibition of gastric mucosal injury by Punica granatum L. (pomegranate) methanolic extract. J Ethnopharmacol 96(1\u20132):171\u2013176. https:\/\/doi.org\/10.1016\/j.jep.2004.09.007","journal-title":"J Ethnopharmacol"},{"issue":"2","key":"10321_CR19","doi-asserted-by":"publisher","first-page":"236","DOI":"10.4103\/0975-7406.80778","volume":"3","author":"P Kalra","year":"2011","unstructured":"Kalra P, Sharma S, Kumar S (2011) Antiulcer effect of the methanolic extract of Tamarindus indica seeds in different experimental models. J Pharm Bioallied Sci 3(2):236\u2013241. https:\/\/doi.org\/10.4103\/0975-7406.80778","journal-title":"J Pharm Bioallied Sci"},{"key":"10321_CR20","doi-asserted-by":"publisher","first-page":"985","DOI":"10.1007\/s00210-016-1262-2","volume":"389","author":"FA dos Reis L\u00edvero","year":"2016","unstructured":"dos Reis L\u00edvero FA, Da Silva LM, Ferreira DM, Galuppo LF, Borato DG, Prando TBL, Acco A (2016) Hydroethanolic extract of Baccharis trimera promotes gastroprotection and healing of acute and chronic gastric ulcers induced by ethanol and acetic acid. Naunyn Schmiedebergs Arch Pharmaco 389:985\u2013998. https:\/\/doi.org\/10.1007\/s00210-016-1262-2","journal-title":"Naunyn Schmiedebergs Arch Pharmaco"},{"issue":"2","key":"10321_CR21","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3923\/rjphyto.2016","volume":"10","author":"TA Ngenge","year":"2016","unstructured":"Ngenge TA, Carol DME, Emmanuel T, Vernyuy TP, Joseph MT, Popova M, Bankova V (2016) Chemical constituents and anti-ulcer activity of propolis from the North-West region of Cameroon. Res J Phytochem 10(2):45\u201357. https:\/\/doi.org\/10.3923\/rjphyto.2016","journal-title":"Res J Phytochem"},{"issue":"1\u20132","key":"10321_CR22","doi-asserted-by":"publisher","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","volume":"72","author":"MM Bradford","year":"1976","unstructured":"Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72(1\u20132):248\u2013254. https:\/\/doi.org\/10.1016\/0003-2697(76)90527-3","journal-title":"Anal Biochem"},{"issue":"1","key":"10321_CR23","doi-asserted-by":"publisher","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","volume":"82","author":"GL Ellman","year":"1959","unstructured":"Ellman GL (1959) Tissue sulfhydryl groups. Arch Biochem Biophys 82(1):70\u201377","journal-title":"Arch Biochem Biophys"},{"issue":"2","key":"10321_CR24","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95(2):351\u2013358. https:\/\/doi.org\/10.1016\/0003-2697(79)90738-3","journal-title":"Anal Biochem"},{"issue":"1\u20132","key":"10321_CR25","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1016\/j.jep.2005.10.028","volume":"105","author":"E Sanmugapriya","year":"2006","unstructured":"Sanmugapriya E, Venkataraman S (2006) Studies on hepatoprotective and antioxidant actions of Strychnos potatorum Linn. seeds on CCl4-induced acute hepatic injury in experimental rats. J Ethnopharmacol 105(1\u20132):154\u2013160. https:\/\/doi.org\/10.1016\/j.jep.2005.10.028","journal-title":"J Ethnopharmacol"},{"key":"10321_CR26","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1016\/S0076-6879(84)05015-1","volume":"105","author":"L Flohe","year":"1984","unstructured":"Flohe L, G\u00fcnzler WA (1984) [12] Assays of glutathione peroxidase. Methods Enzymol 105:114\u2013120. https:\/\/doi.org\/10.1016\/S0076-6879(84)05015-1","journal-title":"Methods Enzymol"},{"key":"10321_CR27","doi-asserted-by":"publisher","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","volume":"249","author":"WH Habig","year":"1974","unstructured":"Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione-S-transferases: The first step in enzymatic mercapturic acid formation. J Biol Chem 249:7130\u20137139","journal-title":"J Biol Chem"},{"issue":"3","key":"10321_CR28","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","volume":"47","author":"S Marklund","year":"1974","unstructured":"Marklund S, Marklund G (1974) Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 47(3):469\u2013474","journal-title":"Eur J Biochem"},{"key":"10321_CR29","first-page":"283","volume-title":"Handbook of methods for oxygen radical research","author":"AJFCP Claiborne","year":"1985","unstructured":"Claiborne AJFCP (1985) Handbook of methods for oxygen radical research. CRC Press Boca Raton, Florida, pp 283\u2013284"},{"issue":"8","key":"10321_CR30","doi-asserted-by":"publisher","first-page":"827","DOI":"10.1016\/j.acthis.2013.04.005","volume":"115","author":"D Akakin","year":"2013","unstructured":"Akakin D, Kiran D, Ozkan N, Er\u015fahin M, Ozdemir-Kumral ZN, Ye\u011fen B, \u015eener G (2013) Protective effects of melatonin against spinal cord injury induced oxidative damage in rat kidney: A morphological and biochemical study. Acta Histocheme 115(8):827\u2013834. https:\/\/doi.org\/10.1016\/j.acthis.2013.04.005","journal-title":"Acta Histocheme"},{"issue":"4","key":"10321_CR31","doi-asserted-by":"publisher","first-page":"590","DOI":"10.3109\/08923973.2011.641971","volume":"34","author":"K Abdelouhab","year":"2012","unstructured":"Abdelouhab K, Rafa H, Toumi R, Bouaziz S, Medjeber O, Touil-Boukoffa C (2012) Mucosal intestinal alteration in experimental colitis correlates with nitric oxide production by peritoneal macrophages: Effect of probiotics and prebiotics. Immunopharmacol Immunotoxicol 34(4):590\u2013597. https:\/\/doi.org\/10.3109\/08923973.2011.641971","journal-title":"Immunopharmacol Immunotoxicol"},{"issue":"6","key":"10321_CR32","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1111\/j.1440-1746.2007.04840.x","volume":"22","author":"S Santhosh","year":"2007","unstructured":"Santhosh S, Anandan R, Sini TK, Mathew PT (2007) Protective effect of glucosamine against ibuprofen-induced peptic ulcer in rats. J Gastroenterol Hepatol 22(6):949\u2013953. https:\/\/doi.org\/10.1111\/j.1440-1746.2007.04840.x","journal-title":"J Gastroenterol Hepatol"},{"issue":"3","key":"10321_CR33","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1159\/000275146","volume":"85","author":"P Girard","year":"2010","unstructured":"Girard P, Copp\u00e9 MC, Pansart Y, Gillardin JM (2010) Gastroprotective effect of Saccharomyces boulardii in a rat model of ibuprofen-induced gastric ulcer. Pharmacolo 85(3):188\u2013193. https:\/\/doi.org\/10.1159\/000275146","journal-title":"Pharmacolo"},{"issue":"3","key":"10321_CR34","doi-asserted-by":"publisher","first-page":"2679","DOI":"10.1039\/C9FO02474C","volume":"11","author":"R Wang","year":"2020","unstructured":"Wang R, Zeng X, Liu B, Yi R, Zhou X, Mu J, Zhao X (2020) Prophylactic effect of Lactobacillus plantarum KSFY06 on HCl\/ethanol-induced gastric injury in mice. Food Funct 11(3):2679\u20132692. https:\/\/doi.org\/10.1039\/C9FO02474C","journal-title":"Food Funct"},{"key":"10321_CR35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s13765-020-00536-8","volume":"63","author":"F Li","year":"2020","unstructured":"Li F, Sun H, Ran G, Liu X, Yi R, Tan F, Liu H (2020) Preventive effect of Lactobacillus plantarum HFY09 on HCl\/ ethanol-induced gastric injury in mice. Appl Biol Chem 63:1\u201311. https:\/\/doi.org\/10.1186\/s13765-020-00536-8","journal-title":"Appl Biol Chem"},{"issue":"4","key":"10321_CR36","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S0016-5085(19)34720-1","volume":"47","author":"RG Bianchi","year":"1964","unstructured":"Bianchi RG, Cook DL (1964) Antipeptic and antiulcerogenic properties of a synthetic sulfated polysaccharide (SN-263). Gastroenterol 47(4):409\u2013414. https:\/\/doi.org\/10.1016\/S0016-5085(19)34720-1","journal-title":"Gastroenterol"},{"key":"10321_CR37","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/j.toxrep.2017.11.004","volume":"4","author":"MA Adefisayo","year":"2017","unstructured":"Adefisayo MA, Akomolafe RO, Akinsomisoye SO, Alabi QK, Ogundipe OL, Omole JG, Olamilosoye KP (2017) Gastro-protective effect of methanol extract of Vernonia amygdalina (del.) leaf on aspirin-induced gastric ulcer in Wistar rats. Toxicol Rep 4:625\u2013633. https:\/\/doi.org\/10.1016\/j.toxrep.2017.11.004","journal-title":"Toxicol Rep"},{"key":"10321_CR38","doi-asserted-by":"publisher","first-page":"339","DOI":"10.1007\/s00580-018-2852-9","volume":"28","author":"S Goorani","year":"2019","unstructured":"Goorani S, Zhaleh M, Zangeneh A, Koohi MK, Rashidi K, Moradi R, Zangeneh MM (2019) The aqueous extract of Glycyrrhiza glabra effectively prevents induced gastroduodenal ulcers: Experimental study on Wistar rats. Comp Clin Path 28:339\u2013347. https:\/\/doi.org\/10.1007\/s00580-018-2852-9","journal-title":"Comp Clin Path"},{"issue":"2","key":"10321_CR39","doi-asserted-by":"publisher","first-page":"15","DOI":"10.32819\/2022.10008","volume":"10","author":"AY Lisna","year":"2022","unstructured":"Lisna AY, Stepchenko LM (2022) Haematological changes in laboratory rats with Ibuprofen-induced gastric ulcer treated with Humilid. Theor Appl Vet Med 10(2):15\u201322. https:\/\/doi.org\/10.32819\/2022.10008","journal-title":"Theor Appl Vet Med"},{"issue":"1","key":"10321_CR40","doi-asserted-by":"publisher","first-page":"7","DOI":"10.5923\/j.ajb.20190901.03","volume":"9","author":"OK Afolabi","year":"2019","unstructured":"Afolabi OK, Oyewo EB, Adeleke GE, Badmus JA, Wusu AD (2019) Mitigation of aluminium phosphide-induced hematotoxicity and ovarian oxidative damage in Wistar rats by hesperidin. Am J Biochem 9(1):7\u201316. https:\/\/doi.org\/10.5923\/j.ajb.20190901.03","journal-title":"Am J Biochem"},{"issue":"12","key":"10321_CR41","doi-asserted-by":"publisher","first-page":"101","DOI":"10.4236\/jbm.2017.512011","volume":"5","author":"KO Ajeigbe","year":"2017","unstructured":"Ajeigbe KO, Jaja LE, Onifade AA, Obabueki PO, Owonikoko WM (2017) Folic acid supplementation ameliorates inflammation and apoptosis in ethanol-induced gastric ulceration in rats. J Biosci Med 5(12):101\u2013117. https:\/\/doi.org\/10.4236\/jbm.2017.512011","journal-title":"J Biosci Med"},{"issue":"2","key":"10321_CR42","doi-asserted-by":"publisher","first-page":"237","DOI":"10.53555\/jptcp.v28i2.3704","volume":"28","author":"WMS Ahmed","year":"2021","unstructured":"Ahmed WMS, Amer AESA, Fayed EM, Dmerdash M, El-Gazzar UB, Genedy D, Awad MM (2021) Comparative study of the possible gastroprotective effect of probiotic (Lactobacillus plantarum) and ranitidine on indomethacin induced gastric ulcer in adult male albino rat. J Popul Ther Clin Pharmacol 28(2):237\u2013253. https:\/\/doi.org\/10.53555\/jptcp.v28i2.3704","journal-title":"J Popul Ther Clin Pharmacol"},{"issue":"11","key":"10321_CR43","doi-asserted-by":"publisher","first-page":"1334","DOI":"10.1111\/j.1745-7254.2005.00186.x","volume":"26","author":"LR Pan","year":"2005","unstructured":"Pan LR, Tang Q, Fu Q, Hu BR, Xiang JZ, Qian JQ (2005) Roles of nitric oxide in protective effect of berberine in ethanol-induced gastric ulcer mice. Acta Pharmacol Sin 26(11):1334\u20131338. https:\/\/doi.org\/10.1111\/j.1745-7254.2005.00186.x","journal-title":"Acta Pharmacol Sin"},{"issue":"21","key":"10321_CR44","doi-asserted-by":"publisher","first-page":"11985","DOI":"10.3390\/ijms222111985","volume":"22","author":"WS Li","year":"2021","unstructured":"Li WS, Lin SC, Chu CH, Chang YK, Zhang X, Lin CC, Tung YT (2021) The gastroprotective effect of naringenin against ethanol-induced gastric ulcers in mice through inhibiting oxidative and inflammatory responses. Int J Mol Sci 22(21):11985. https:\/\/doi.org\/10.3390\/ijms222111985","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10321_CR45","doi-asserted-by":"publisher","first-page":"213","DOI":"10.21608\/ejhm.2023.279317","volume":"90","author":"HR Mousa","year":"2023","unstructured":"Mousa HR, Fahmy N (2023) Gastroprotective and healing effect of naringin and quercetin in experimentally induced gastric ulcer by diclofenac sodium in adult male albino rat: A histological and immunohistochemical study. Egypt J Hosp Med 90(1):213\u2013225. https:\/\/doi.org\/10.21608\/ejhm.2023.279317","journal-title":"Egypt J Hosp Med"},{"issue":"9","key":"10321_CR46","doi-asserted-by":"publisher","first-page":"2285","DOI":"10.3390\/microorganisms11092285","volume":"11","author":"H Jin","year":"2023","unstructured":"Jin H, Park SK, Yun YG, Song NE, Baik SH (2023) Isolation of Latilactobacillus curvatus with enhanced nitric oxide synthesis from Korean traditional fermented food and investigation of its probiotic properties. Microorganisms 11(9):2285. https:\/\/doi.org\/10.3390\/microorganisms11092285","journal-title":"Microorganisms"},{"issue":"2","key":"10321_CR47","first-page":"102","volume":"34","author":"M Bartoskova","year":"2013","unstructured":"Bartoskova M, Dobsikova R, Stancova V, Zivna D, Blahova J, Marsalek P, Faggio C (2013) Evaluation of ibuprofen toxicity for zebrafish (Danio rerio) targeting on selected biomarkers of oxidative stress. Neuro Endocrinol Lett 34(2):102\u2013108","journal-title":"Neuro Endocrinol Lett"},{"key":"10321_CR48","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12906-017-1992-9","volume":"17","author":"H Siti Zawanah","year":"2017","unstructured":"Siti Zawanah H, Zainul Amiruddin O, Maizatul Hasyima O, Mohtarrudin N, Ikarastika R, Abdul W, Nazrul M, Abdullah H (2017) Synergistic gastroprotective activity of methanolic extract of a mixture of Melastoma malabathricum and Muntingia calabura leaves in rats. BMC Complement Altern Med 17:1\u201316. https:\/\/doi.org\/10.1186\/s12906-017-1992-9","journal-title":"BMC Complement Altern Med"},{"issue":"12","key":"10321_CR49","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.3109\/13880209.2014.905794","volume":"52","author":"D Laloo","year":"2014","unstructured":"Laloo D, Prasad SK, Sairam K, Hemalatha S (2014) Gastroprotective activity of polyphenolic-rich extract of Potentilla mooniana. Pharm Biol 52(12):1532\u20131542. https:\/\/doi.org\/10.3109\/13880209.2014.905794","journal-title":"Pharm Biol"},{"key":"10321_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10856-018-6132-7","volume":"29","author":"H Radhouani","year":"2018","unstructured":"Radhouani H, Gon\u00e7alves C, Maia FR, Oliveira JM, Reis RL (2018) Biological performance of a promising Kefiran-biopolymer with potential in regenerative medicine applications: A comparative study with hyaluronic acid. J Mater Sci Mater Med 29:1\u201310. https:\/\/doi.org\/10.1007\/s10856-018-6132-7","journal-title":"J Mater Sci Mater Med"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-024-10321-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-024-10321-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-024-10321-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,20]],"date-time":"2025-11-20T12:44:00Z","timestamp":1763642640000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-024-10321-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,15]]},"references-count":50,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["10321"],"URL":"https:\/\/doi.org\/10.1007\/s12602-024-10321-4","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,15]]},"assertion":[{"value":"8 July 2024","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"15 July 2024","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"All in vivo experimental assays were carried out in conformity with international guidelines for the care and use of laboratory animals.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}}]}}