{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T17:22:35Z","timestamp":1783099355287,"version":"3.54.6"},"reference-count":146,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T00:00:00Z","timestamp":1745625600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics &amp; Antimicro. Prot."],"published-print":{"date-parts":[[2025,8]]},"DOI":"10.1007\/s12602-025-10553-y","type":"journal-article","created":{"date-parts":[[2025,4,26]],"date-time":"2025-04-26T05:59:16Z","timestamp":1745647156000},"page":"2571-2585","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Probiotics as a Treatment of Chronic Stress Associated Abnormalities"],"prefix":"10.1007","volume":"17","author":[{"given":"Vipul","family":"Agarwal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rishabh","family":"Chaudhary","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anugya","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,4,26]]},"reference":[{"issue":"10","key":"10553_CR1","doi-asserted-by":"publisher","first-page":"5085","DOI":"10.3390\/ijms25105085","volume":"25","author":"AG White","year":"2024","unstructured":"White AG, Elias E, Orozco A, Robinson SA, Manners MT (2024) Chronic stress-induced neuroinflammation: relevance of rodent models to human disease. Int J Mol Sci 25(10):5085. https:\/\/doi.org\/10.3390\/ijms25105085","journal-title":"Int J Mol Sci"},{"key":"10553_CR2","doi-asserted-by":"publisher","first-page":"116425","DOI":"10.1016\/j.biopha.2024.116425","volume":"173","author":"Y Zhou","year":"2024","unstructured":"Zhou Y, Huang Y, Ye W et al (2024) Cynaroside improved depressive-like behavior in CUMS mice by suppressing microglial inflammation and ferroptosis. Biomed Pharmacother 173:116425. https:\/\/doi.org\/10.1016\/j.biopha.2024.116425","journal-title":"Biomed Pharmacother"},{"key":"10553_CR3","doi-asserted-by":"publisher","first-page":"4121","DOI":"10.7150\/jca.52658","volume":"12","author":"J Zheng","year":"2021","unstructured":"Zheng J, Cai W, Lu X et al (2021) Chronic stress accelerates the process of gastric precancerous lesions in rats. J Cancer 12:4121\u20134133. https:\/\/doi.org\/10.7150\/jca.52658","journal-title":"J Cancer"},{"key":"10553_CR4","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1111\/jcmm.12167","volume":"18","author":"S Vignjevi\u0107","year":"2014","unstructured":"Vignjevi\u0107 S, Bude\u010d M, Markovi\u0107 D et al (2014) Chronic psychological stress activates BMP4-dependent extramedullary erythropoiesis. J Cell Mol Med 18:91\u2013103. https:\/\/doi.org\/10.1111\/jcmm.12167","journal-title":"J Cell Mol Med"},{"key":"10553_CR5","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1007\/s12020-014-0307-x","volume":"48","author":"Y Han","year":"2015","unstructured":"Han Y, Lin M, Wang X et al (2015) Basis of aggravated hepatic lipid metabolism by chronic stress in high-fat diet-fed rat. Endocrine 48:483\u2013492. https:\/\/doi.org\/10.1007\/s12020-014-0307-x","journal-title":"Endocrine"},{"issue":"18","key":"10553_CR6","doi-asserted-by":"publisher","first-page":"9922","DOI":"10.3390\/ijerph18189922","volume":"18","author":"BA Franklin","year":"2021","unstructured":"Franklin BA, Rusia A, Haskin-Popp C, Tawney A (2021) Chronic stress, exercise and cardiovascular disease: placing the benefits and risks of physical activity into perspective. Int J Environ Res Public Health 18(18):9922. https:\/\/doi.org\/10.3390\/ijerph18189922","journal-title":"Int J Environ Res Public Health"},{"key":"10553_CR7","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-023-02611-5","author":"V Agarwal","year":"2023","unstructured":"Agarwal V, Kaushik AS, Chaudhary R et al (2023) Transcutaneous vagus nerve stimulation ameliorates cardiac abnormalities in chronically stressed rats. Naunyn Schmiedebergs Arch Pharmacol. https:\/\/doi.org\/10.1007\/s00210-023-02611-5","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10553_CR8","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-024-03205-5","author":"A Gupta","year":"2024","unstructured":"Gupta A, Agarwal V (2024) Inflammation as a shared mechanism of chronic stress related disorders with potential novel therapeutic targets. Naunyn Schmiedebergs Arch Pharmacol. https:\/\/doi.org\/10.1007\/s00210-024-03205-5","journal-title":"Naunyn Schmiedebergs Arch Pharmacol"},{"key":"10553_CR9","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1186\/s11689-020-09337-y","volume":"12","author":"KE Smith","year":"2020","unstructured":"Smith KE, Pollak SD (2020) Estr\u00e9s y desarrollo en la vida temprana: mecanismos potenciales para resultados adversos. J Neurodev Disord 12:34","journal-title":"J Neurodev Disord"},{"issue":"21","key":"10553_CR10","doi-asserted-by":"publisher","first-page":"6394","DOI":"10.3390\/jcm13216394","volume":"13","author":"A Alotiby","year":"2024","unstructured":"Alotiby A (2024) Immunology of stress: a review article. J Clin Med 13(21):6394. https:\/\/doi.org\/10.3390\/jcm13216394","journal-title":"J Clin Med"},{"key":"10553_CR11","doi-asserted-by":"publisher","first-page":"166","DOI":"10.1016\/j.socscimed.2014.08.009","volume":"118","author":"F Rutters","year":"2014","unstructured":"Rutters F, Pilz S, Koopman AD et al (2014) The association between psychosocial stress and mortality is mediated by lifestyle and chronic diseases: the Hoorn study. Soc Sci Med 118:166\u2013172. https:\/\/doi.org\/10.1016\/j.socscimed.2014.08.009","journal-title":"Soc Sci Med"},{"key":"10553_CR12","doi-asserted-by":"publisher","first-page":"603","DOI":"10.1002\/cphy.c150015","volume":"6","author":"JP Herman","year":"2016","unstructured":"Herman JP, McKlveen JM, Ghosal S et al (2016) Regulation of the hypothalamic-pituitary-adrenocortical stress response. Compr Physiol 6:603\u2013621. https:\/\/doi.org\/10.1002\/cphy.c150015","journal-title":"Compr Physiol"},{"key":"10553_CR13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fnbeh.2020.601939","volume":"14","author":"JA Sheng","year":"2021","unstructured":"Sheng JA, Bales NJ, Myers SA et al (2021) The hypothalamic-pituitary-adrenal axis: development, programming actions of hormones, and maternal-fetal interactions. Front Behav Neurosci 14:1\u201321. https:\/\/doi.org\/10.3389\/fnbeh.2020.601939","journal-title":"Front Behav Neurosci"},{"issue":"9","key":"10553_CR14","doi-asserted-by":"publisher","first-page":"220","DOI":"10.3390\/diseases12090220","volume":"12","author":"A Sic","year":"2024","unstructured":"Sic A, Cvetkovic K, Manchanda E, Knezevic NN (2024) Neurobiological implications of chronic stress and metabolic dysregulation in inflammatory bowel diseases. Diseases 12(9):220. https:\/\/doi.org\/10.3390\/diseases12090220","journal-title":"Diseases"},{"issue":"23","key":"10553_CR15","doi-asserted-by":"publisher","first-page":"2726","DOI":"10.3390\/cells12232726","volume":"12","author":"E Knezevic","year":"2023","unstructured":"Knezevic E, Nenic K, Milanovic V, Knezevic NN (2023) The role of cortisol in chronic stress, neurodegenerative diseases, and psychological disorders. Cells 12(23):2726. https:\/\/doi.org\/10.3390\/cells12232726","journal-title":"Cells"},{"key":"10553_CR16","doi-asserted-by":"publisher","first-page":"127","DOI":"10.3389\/fnbeh.2018.00127","volume":"12","author":"LD Godoy","year":"2018","unstructured":"Godoy LD, Rossignoli MT, Delfino-Pereira P et al (2018) A comprehensive overview on stress neurobiology: basic concepts and clinical implications. Front Behav Neurosci 12:127. https:\/\/doi.org\/10.3389\/fnbeh.2018.00127","journal-title":"Front Behav Neurosci"},{"issue":"Suppl 2","key":"10553_CR17","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1111\/rda.14444","volume":"58","author":"M Kaiser","year":"2023","unstructured":"Kaiser M, Jaillardon L (2023) Pathogenesis of the crosstalk between reproductive function and stress in animals-part 1: hypothalamo-pituitary-adrenal axis, sympatho-adrenomedullary system and kisspeptin. Reprod Domest Anim 58(Suppl 2):176\u2013183. https:\/\/doi.org\/10.1111\/rda.14444","journal-title":"Reprod Domest Anim"},{"key":"10553_CR18","doi-asserted-by":"publisher","first-page":"780616","DOI":"10.1155\/2014\/780616","volume":"2014","author":"R Tian","year":"2014","unstructured":"Tian R, Hou G, Li D, Yuan TF (2014) A possible change process of inflammatory cytokines in the prolonged chronic stress and its ultimate implications for health. Sci World J 2014:780616. https:\/\/doi.org\/10.1155\/2014\/780616","journal-title":"Sci World J"},{"issue":"12","key":"10553_CR19","doi-asserted-by":"publisher","first-page":"e08522","DOI":"10.1016\/j.heliyon.2021.e08522","volume":"7","author":"V Agarwal","year":"2021","unstructured":"Agarwal V, Kaushik AS, Rehman M et al (2021) Interleukin-6 expression and its modulation by diacerein in a rat model of chronic stress induced cardiac dysfunction. Heliyon 7(12):e08522. https:\/\/doi.org\/10.1016\/j.heliyon.2021.e08522","journal-title":"Heliyon"},{"key":"10553_CR20","doi-asserted-by":"publisher","first-page":"114207","DOI":"10.1016\/j.physbeh.2023.114207","volume":"267","author":"M Rehman","year":"2023","unstructured":"Rehman M, Chaudhary R, Rajput S et al (2023) Butein ameliorates chronic stress induced atherosclerosis via targeting anti-inflammatory, anti-fibrotic and BDNF pathways. Physiol Behav 267:114207. https:\/\/doi.org\/10.1016\/j.physbeh.2023.114207","journal-title":"Physiol Behav"},{"key":"10553_CR21","doi-asserted-by":"publisher","first-page":"111046","DOI":"10.1016\/j.intimp.2023.111046","volume":"125","author":"R Chaudhary","year":"2023","unstructured":"Chaudhary R, Prasad A, Agarwal V et al (2023) Chronic stress predisposes to the aggravation of inflammation in autoimmune diseases with focus on rheumatoid arthritis and psoriasis. Int Immunopharmacol 125:111046. https:\/\/doi.org\/10.1016\/j.intimp.2023.111046","journal-title":"Int Immunopharmacol"},{"key":"10553_CR22","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1016\/j.jdsr.2022.11.003","volume":"58","author":"D Paudel","year":"2022","unstructured":"Paudel D, Uehara O, Giri S et al (2022) Effect of psychological stress on the oral-gut microbiota and the potential oral-gut-brain axis. Jpn Dent Sci Rev 58:365\u2013375. https:\/\/doi.org\/10.1016\/j.jdsr.2022.11.003","journal-title":"Jpn Dent Sci Rev"},{"key":"10553_CR23","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1016\/j.ynstr.2017.03.001","volume":"7","author":"JA Foster","year":"2017","unstructured":"Foster JA, Rinaman L, Cryan JF (2017) Stress & the gut-brain axis: regulation by the microbiome. Neurobiol Stress 7:124\u2013136. https:\/\/doi.org\/10.1016\/j.ynstr.2017.03.001","journal-title":"Neurobiol Stress"},{"key":"10553_CR24","doi-asserted-by":"publisher","first-page":"105","DOI":"10.1016\/j.cobeha.2019.01.011","volume":"28","author":"A Madison","year":"2019","unstructured":"Madison A, Kiecolt-Glaser JK (2019) Stress, depression, diet, and the gut microbiota: human-bacteria interactions at the core of psychoneuroimmunology and nutrition. Curr Opin Behav Sci 28:105\u2013110. https:\/\/doi.org\/10.1016\/j.cobeha.2019.01.011","journal-title":"Curr Opin Behav Sci"},{"key":"10553_CR25","doi-asserted-by":"publisher","first-page":"1877","DOI":"10.1152\/physrev.00018.2018","volume":"99","author":"JF Cryan","year":"2019","unstructured":"Cryan JF, O\u2019Riordan KJ, Cowan CSM et al (2019) The microbiota-gut-brain axis. Physiol Rev 99:1877\u20132013. https:\/\/doi.org\/10.1152\/physrev.00018.2018","journal-title":"Physiol Rev"},{"key":"10553_CR26","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1016\/j.tins.2013.01.005","volume":"36","author":"JA Foster","year":"2013","unstructured":"Foster JA, McVey Neufeld K-A (2013) Gut-brain axis: how the microbiome influences anxiety and depression. Trends Neurosci 36:305\u2013312. https:\/\/doi.org\/10.1016\/j.tins.2013.01.005","journal-title":"Trends Neurosci"},{"issue":"6","key":"10553_CR27","doi-asserted-by":"publisher","first-page":"2099","DOI":"10.3390\/nu13062099","volume":"13","author":"Y Chen","year":"2021","unstructured":"Chen Y, Xu J, Chen Y (2021) Regulation of neurotransmitters by the gut microbiota and effects on cognition in neurological disorders. Nutrients 13(6):2099. https:\/\/doi.org\/10.3390\/nu13062099","journal-title":"Nutrients"},{"key":"10553_CR28","doi-asserted-by":"publisher","first-page":"25","DOI":"10.3389\/fendo.2020.00025","volume":"11","author":"YP Silva","year":"2020","unstructured":"Silva YP, Bernardi A, Frozza RL (2020) The role of short-chain fatty acids from gut microbiota in gut-brain communication. Front Endocrinol (Lausanne) 11:25. https:\/\/doi.org\/10.3389\/fendo.2020.00025","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10553_CR29","doi-asserted-by":"publisher","first-page":"1500","DOI":"10.1053\/j.gastro.2014.02.037","volume":"146","author":"EA Mayer","year":"2014","unstructured":"Mayer EA, Savidge T, Shulman RJ (2014) Brain-gut microbiome interactions and functional bowel disorders. Gastroenterology 146:1500\u20131512. https:\/\/doi.org\/10.1053\/j.gastro.2014.02.037","journal-title":"Gastroenterology"},{"key":"10553_CR30","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1093\/procel\/pwad026","volume":"14","author":"Q Wang","year":"2023","unstructured":"Wang Q, Yang Q, Liu X (2023) The microbiota\u2013gut\u2013brain axis and neurodevelopmental disorders. Protein Cell 14:762\u2013775. https:\/\/doi.org\/10.1093\/procel\/pwad026","journal-title":"Protein Cell"},{"key":"10553_CR31","doi-asserted-by":"publisher","first-page":"104621","DOI":"10.1016\/j.nbd.2019.104621","volume":"134","author":"C Gubert","year":"2020","unstructured":"Gubert C, Kong G, Renoir T, Hannan AJ (2020) Exercise, diet and stress as modulators of gut microbiota: implications for neurodegenerative diseases. Neurobiol Dis 134:104621. https:\/\/doi.org\/10.1016\/j.nbd.2019.104621","journal-title":"Neurobiol Dis"},{"key":"10553_CR32","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1007\/s00335-013-9488-5","volume":"25","author":"RD Moloney","year":"2014","unstructured":"Moloney RD, Desbonnet L, Clarke G et al (2014) The microbiome: stress, health and disease. Mamm Genome 25:49\u201374. https:\/\/doi.org\/10.1007\/s00335-013-9488-5","journal-title":"Mamm Genome"},{"key":"10553_CR33","doi-asserted-by":"publisher","unstructured":"Ahmed GK, Karam H, Ramadan A et al (2024) Bridging the gap: associations between gut microbiota and psychiatric disorders. Middle East Curr Psychiatry 9:.https:\/\/doi.org\/10.1186\/s43045-024-00395-9","DOI":"10.1186\/s43045-024-00395-9"},{"key":"10553_CR34","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.ynstr.2016.03.001","volume":"4","author":"K Rea","year":"2016","unstructured":"Rea K, Dinan TG, Cryan JF (2016) The microbiome: a key regulator of stress and neuroinflammation. Neurobiol Stress 4:23\u201333. https:\/\/doi.org\/10.1016\/j.ynstr.2016.03.001","journal-title":"Neurobiol Stress"},{"issue":"4","key":"10553_CR35","doi-asserted-by":"publisher","first-page":"723","DOI":"10.3390\/microorganisms9040723","volume":"9","author":"T Bear","year":"2021","unstructured":"Bear T, Dalziel J, Coad J, Roy N, Butts C, Gopal P (2021) The microbiome-gut-brain axis and resilience to developing anxiety or depression under stress. Microorganisms 9(4):723. https:\/\/doi.org\/10.3390\/microorganisms9040723","journal-title":"Microorganisms"},{"key":"10553_CR36","doi-asserted-by":"publisher","first-page":"720","DOI":"10.1016\/j.biopsych.2013.05.001","volume":"74","author":"TG Dinan","year":"2013","unstructured":"Dinan TG, Stanton C, Cryan JF (2013) Psychobiotics: a novel class of psychotropic. Biol Psychiatry 74:720\u2013726. https:\/\/doi.org\/10.1016\/j.biopsych.2013.05.001","journal-title":"Biol Psychiatry"},{"key":"10553_CR37","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1016\/j.tins.2016.09.002","volume":"39","author":"A Sarkar","year":"2016","unstructured":"Sarkar A, Lehto SM, Harty S et al (2016) Psychobiotics and the manipulation of bacteria-gut-brain signals. Trends Neurosci 39:763\u2013781. https:\/\/doi.org\/10.1016\/j.tins.2016.09.002","journal-title":"Trends Neurosci"},{"key":"10553_CR38","doi-asserted-by":"publisher","first-page":"178","DOI":"10.1016\/j.tifs.2023.06.013","volume":"138","author":"T Ma","year":"2023","unstructured":"Ma T, Shen X, Shi X et al (2023) Targeting gut microbiota and metabolism as the major probiotic mechanism - an evidence-based review. Trends Food Sci Technol 138:178\u2013198. https:\/\/doi.org\/10.1016\/j.tifs.2023.06.013","journal-title":"Trends Food Sci Technol"},{"issue":"7","key":"10553_CR39","doi-asserted-by":"publisher","first-page":"1428","DOI":"10.3390\/microorganisms10071428","volume":"10","author":"GU Varela-Trinidad","year":"2022","unstructured":"Varela-Trinidad GU, Dom\u00ednguez-D\u00edaz C, Sol\u00f3rzano-Castanedo K et al (2022) Probiotics: protecting our health from the gut. Microorganisms 10(7):1428. https:\/\/doi.org\/10.3390\/microorganisms10071428","journal-title":"Microorganisms"},{"key":"10553_CR40","doi-asserted-by":"publisher","first-page":"1216674","DOI":"10.3389\/fmicb.2023.1216674","volume":"14","author":"A Latif","year":"2023","unstructured":"Latif A, Shehzad A, Niazi S et al (2023) Probiotics: mechanism of action, health benefits and their application in food industries. Front Microbiol 14:1216674. https:\/\/doi.org\/10.3389\/fmicb.2023.1216674","journal-title":"Front Microbiol"},{"key":"10553_CR41","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.neubiorev.2019.03.023","volume":"102","author":"RT Liu","year":"2019","unstructured":"Liu RT, Walsh RFL, Sheehan AE (2019) Prebiotics and probiotics for depression and anxiety: a systematic review and meta-analysis of controlled clinical trials. Neurosci Biobehav Rev 102:13\u201323. https:\/\/doi.org\/10.1016\/j.neubiorev.2019.03.023","journal-title":"Neurosci Biobehav Rev"},{"key":"10553_CR42","doi-asserted-by":"publisher","first-page":"115246","DOI":"10.1016\/j.bbr.2024.115246","volume":"476","author":"MF Khan","year":"2025","unstructured":"Khan MF, Khodve G, Yadav S et al (2025) Probiotic treatment improves post-traumatic stress disorder outcomes in mice. Behav Brain Res 476:115246. https:\/\/doi.org\/10.1016\/j.bbr.2024.115246","journal-title":"Behav Brain Res"},{"key":"10553_CR43","doi-asserted-by":"publisher","first-page":"E221023222518","DOI":"10.2174\/0126668629257875230920091340","volume":"3","author":"M Ghasvarian","year":"2025","unstructured":"Ghasvarian M, Mahboobi S, Sadeghi R et al (2025) Effects of probiotics and magnesium co-supplementation on stress levels and quality of life in obese patients with depressed mood: a randomized, double-blinded placebo-controlled clinical trial. Curr Funct Foods 3:E221023222518","journal-title":"Curr Funct Foods"},{"key":"10553_CR44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-024-60029-2","volume":"14","author":"M Sarkawi","year":"2024","unstructured":"Sarkawi M, Raja Ali RA, Abdul Wahab N et al (2024) A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep 14:1\u201314. https:\/\/doi.org\/10.1038\/s41598-024-60029-2","journal-title":"Sci Rep"},{"key":"10553_CR45","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fphar.2024.1398292","volume":"15","author":"M Ye","year":"2024","unstructured":"Ye M, Ji F, Huang C et al (2024) A novel probiotic formula, BLLL, ameliorates chronic stress-induced depression-like behaviors in mice by reducing neuroinflammation and increasing neurotrophic factors. Front Pharmacol 15:1\u201315. https:\/\/doi.org\/10.3389\/fphar.2024.1398292","journal-title":"Front Pharmacol"},{"key":"10553_CR46","doi-asserted-by":"publisher","first-page":"450","DOI":"10.1016\/j.jad.2024.03.117","volume":"355","author":"X Li","year":"2024","unstructured":"Li X, Cheng X, Shi Y et al (2024) Mixed probiotics reduce the severity of stress-induced depressive-like behaviors. J Affect Disord 355:450\u2013458. https:\/\/doi.org\/10.1016\/j.jad.2024.03.117","journal-title":"J Affect Disord"},{"issue":"2","key":"10553_CR47","doi-asserted-by":"publisher","first-page":"411","DOI":"10.3390\/microorganisms12020411","volume":"12","author":"E Merkouris","year":"2024","unstructured":"Merkouris E, Mavroudi T, Miliotas D et al (2024) Probiotics\u2019 effects in the treatment of anxiety and depression: a comprehensive review of 2014\u20132023 clinical trials. Microorganisms 12(2):411. https:\/\/doi.org\/10.3390\/microorganisms12020411","journal-title":"Microorganisms"},{"key":"10553_CR48","doi-asserted-by":"publisher","first-page":"2895","DOI":"10.1039\/D3FO03897A","volume":"15","author":"L Jia","year":"2024","unstructured":"Jia L, Xiao L, Fu Y et al (2024) Neuroprotective effects of probiotics on anxiety- and depression-like disorders in stressed mice by modulating tryptophan metabolism and the gut microbiota. Food Funct 15:2895\u20132905. https:\/\/doi.org\/10.1039\/D3FO03897A","journal-title":"Food Funct"},{"key":"10553_CR49","doi-asserted-by":"publisher","first-page":"105710","DOI":"10.1016\/j.jff.2023.105710","volume":"107","author":"J Ma","year":"2023","unstructured":"Ma J, Chen Y, Wang Z et al (2023) Lactiplantibacillus plantarum CR12 attenuates chronic unforeseeable mild stress induced anxiety and depression-like behaviors by modulating the gut microbiota-brain axis. J Funct Foods 107:105710. https:\/\/doi.org\/10.1016\/j.jff.2023.105710","journal-title":"J Funct Foods"},{"key":"10553_CR50","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12974-023-02693-1","volume":"20","author":"J Ma","year":"2023","unstructured":"Ma J, Wang R, Chen Y et al (2023) 5-HT attenuates chronic stress-induced cognitive impairment in mice through intestinal flora disruption. J Neuroinflammation 20:1\u201323. https:\/\/doi.org\/10.1186\/s12974-023-02693-1","journal-title":"J Neuroinflammation"},{"issue":"14","key":"10553_CR51","doi-asserted-by":"publisher","first-page":"3122","DOI":"10.3390\/nu15143122","volume":"15","author":"M Boehme","year":"2023","unstructured":"Boehme M, R\u00e9mond-Derbez N, Lerond C et al (2023) Bifidobacterium longum subsp. longum reduces perceived psychological stress in healthy adults: an exploratory clinical trial. Nutrients 15(14):3122. https:\/\/doi.org\/10.3390\/nu15143122","journal-title":"Nutrients"},{"key":"10553_CR52","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fimmu.2023.1158137","volume":"14","author":"R Zhu","year":"2023","unstructured":"Zhu R, Fang Y, Li H et al (2023) Psychobiotic Lactobacillus plantarum JYLP-326 relieves anxiety, depression, and insomnia symptoms in test anxious college via modulating the gut microbiota and its metabolism. Front Immunol 14:1\u201313. https:\/\/doi.org\/10.3389\/fimmu.2023.1158137","journal-title":"Front Immunol"},{"key":"10553_CR53","doi-asserted-by":"publisher","first-page":"5355","DOI":"10.1039\/d2fo03408e","volume":"14","author":"X Jin","year":"2023","unstructured":"Jin X, Hu Y, Lin T et al (2023) Selenium-enriched Bifidobacterium longum DD98 relieves irritable bowel syndrome induced by chronic unpredictable mild stress in mice. Food Funct 14:5355\u20135374. https:\/\/doi.org\/10.1039\/d2fo03408e","journal-title":"Food Funct"},{"key":"10553_CR54","doi-asserted-by":"publisher","first-page":"e0061520","DOI":"10.1128\/IAI.00615-20","volume":"89","author":"HS Youn","year":"2021","unstructured":"Youn HS, Kim J-H, Lee JS et al (2021) Lactobacillus plantarum reduces low-grade inflammation and glucose levels in a mouse model of chronic stress and diabetes. Infect Immun 89:e0061520. https:\/\/doi.org\/10.1128\/IAI.00615-20","journal-title":"Infect Immun"},{"key":"10553_CR55","doi-asserted-by":"publisher","first-page":"100174","DOI":"10.1016\/j.bbih.2020.100174","volume":"10","author":"GM Moloney","year":"2021","unstructured":"Moloney GM, Long-Smith CM, Murphy A et al (2021) Improvements in sleep indices during exam stress due to consumption of a Bifidobacterium longum. Brain, Behav Immun - Heal 10:100174. https:\/\/doi.org\/10.1016\/j.bbih.2020.100174","journal-title":"Brain, Behav Immun - Heal"},{"key":"10553_CR56","doi-asserted-by":"publisher","first-page":"175","DOI":"10.1016\/j.repbio.2020.03.005","volume":"20","author":"Y Guo","year":"2020","unstructured":"Guo Y, Du X, Bian Y, Wang S (2020) Chronic unpredictable stress-induced reproductive deficits were prevented by probiotics. Reprod Biol 20:175\u2013183. https:\/\/doi.org\/10.1016\/j.repbio.2020.03.005","journal-title":"Reprod Biol"},{"key":"10553_CR57","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/19490976.2020.1782156","volume":"12","author":"C Zhou","year":"2020","unstructured":"Zhou C, Fang X, Xu J et al (2020) Bifidobacterium longum alleviates irritable bowel syndrome-related visceral hypersensitivity and microbiota dysbiosis via Paneth cell regulation. Gut Microbes 12:1\u201317. https:\/\/doi.org\/10.1080\/19490976.2020.1782156","journal-title":"Gut Microbes"},{"key":"10553_CR58","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1080\/1040841X.2021.1902940","volume":"47","author":"TP Singh","year":"2021","unstructured":"Singh TP, Natraj BH (2021) Next-generation probiotics: a promising approach towards designing personalized medicine. Crit Rev Microbiol 47:479\u2013498. https:\/\/doi.org\/10.1080\/1040841X.2021.1902940","journal-title":"Crit Rev Microbiol"},{"key":"10553_CR59","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1038\/nrgastro.2014.66","volume":"11","author":"C Hill","year":"2014","unstructured":"Hill C, Guarner F, Reid G et al (2014) The international scientific association for probiotics and prebiotics consensus statement on the scope and appropriate use of the term probiotic. Nat Rev Gastroenterol Hepatol 11:506\u2013514. https:\/\/doi.org\/10.1038\/nrgastro.2014.66","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10553_CR60","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1111\/j.1574-6968.2012.02593.x","volume":"334","author":"R Nagpal","year":"2012","unstructured":"Nagpal R, Kumar A, Kumar M et al (2012) Probiotics, their health benefits and applications for developing healthier foods: a review. FEMS Microbiol Lett 334:1\u201315. https:\/\/doi.org\/10.1111\/j.1574-6968.2012.02593.x","journal-title":"FEMS Microbiol Lett"},{"key":"10553_CR61","doi-asserted-by":"publisher","first-page":"e420","DOI":"10.1002\/mco2.420","volume":"4","author":"J Ji","year":"2023","unstructured":"Ji J, Jin W, Liu S-J et al (2023) Probiotics, prebiotics, and postbiotics in health and disease. MedComm 4:e420. https:\/\/doi.org\/10.1002\/mco2.420","journal-title":"MedComm"},{"key":"10553_CR62","doi-asserted-by":"publisher","first-page":"561","DOI":"10.3390\/encyclopedia3020040","volume":"3","author":"HN Rabetafika","year":"2023","unstructured":"Rabetafika HN, Razafindralambo A, Ebenso B, Razafindralambo HL (2023) Probiotics as antibiotic alternatives for human and animal applications. Encyclopedia 3:561\u2013581. https:\/\/doi.org\/10.3390\/encyclopedia3020040","journal-title":"Encyclopedia"},{"issue":"12","key":"10553_CR63","doi-asserted-by":"publisher","first-page":"599","DOI":"10.3390\/fermentation10120599","volume":"10","author":"P Vinayamohan","year":"2024","unstructured":"Vinayamohan P, Joseph D, Viju LS et al (2024) Efficacy of probiotics in reducing pathogenic potential of infectious agents. Fermentation 10(12):599. https:\/\/doi.org\/10.3390\/fermentation10120599","journal-title":"Fermentation"},{"issue":"4","key":"10553_CR64","doi-asserted-by":"publisher","first-page":"113","DOI":"10.3390\/fermentation6040113","volume":"6","author":"A Vilela","year":"2020","unstructured":"Vilela A, Cosme F, In\u00eas A (2020) Wine and non-dairy fermented beverages: a novel source of pro-and prebiotics. Fermentation 6(4):113. https:\/\/doi.org\/10.3390\/fermentation6040113","journal-title":"Fermentation"},{"key":"10553_CR65","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1177\/1756283X13482996","volume":"6","author":"CM Guinane","year":"2013","unstructured":"Guinane CM, Cotter PD (2013) Role of the gut microbiota in health and chronic gastrointestinal disease: understanding a hidden metabolic organ. Therap Adv Gastroenterol 6:295\u2013308. https:\/\/doi.org\/10.1177\/1756283X13482996","journal-title":"Therap Adv Gastroenterol"},{"key":"10553_CR66","doi-asserted-by":"publisher","first-page":"110814","DOI":"10.1016\/j.foodres.2021.110814","volume":"150","author":"NARM Rodzi","year":"2021","unstructured":"Rodzi NARM, Lee LK (2021) Traditional fermented foods as vehicle of non-dairy probiotics: perspectives in South East Asia countries. Food Res Int 150:110814. https:\/\/doi.org\/10.1016\/j.foodres.2021.110814","journal-title":"Food Res Int"},{"key":"10553_CR67","doi-asserted-by":"publisher","first-page":"374s","DOI":"10.1093\/ajcn\/73.2.374s","volume":"73","author":"KJ Heller","year":"2001","unstructured":"Heller KJ (2001) Probiotic bacteria in fermented foods: product characteristics and starter organisms. Am J Clin Nutr 73:374s\u2013379s. https:\/\/doi.org\/10.1093\/ajcn\/73.2.374s","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"10553_CR68","doi-asserted-by":"publisher","first-page":"118","DOI":"10.3390\/fermentation9020118","volume":"9","author":"AM Shah","year":"2023","unstructured":"Shah AM, Tarfeen N, Mohamed H, Song Y (2023) Fermented foods: their health-promoting components and potential effects on gut microbiota. Fermentation 9(2):118. https:\/\/doi.org\/10.3390\/fermentation9020118","journal-title":"Fermentation"},{"issue":"8","key":"10553_CR69","doi-asserted-by":"publisher","first-page":"1806","DOI":"10.3390\/nu11081806","volume":"11","author":"E Dimidi","year":"2019","unstructured":"Dimidi E, Cox SR, Rossi M, Whelan K (2019) Fermented foods: definitions and characteristics, impact on the gut microbiota and effects on gastrointestinal health and disease. Nutrients 11(8):1806. https:\/\/doi.org\/10.3390\/nu11081806","journal-title":"Nutrients"},{"key":"10553_CR70","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41575-019-0173-3","volume":"16","author":"M Sanders","year":"2019","unstructured":"Sanders M, Merenstein D, Reid G et al (2019) Probiotics and prebiotics in intestinal health and disease: from biology to the clinic. Nat Rev Gastroenterol Hepatol 16:1. https:\/\/doi.org\/10.1038\/s41575-019-0173-3","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"10553_CR71","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmicb.2020.01662","volume":"11","author":"S Binda","year":"2020","unstructured":"Binda S, Hill C, Johansen E et al (2020) Criteria to qualify microorganisms as \u201cprobiotic\u201d in foods and dietary supplements. Front Microbiol 11:1\u20139. https:\/\/doi.org\/10.3389\/fmicb.2020.01662","journal-title":"Front Microbiol"},{"key":"10553_CR72","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1177\/1756283X12459294","volume":"6","author":"P Hemarajata","year":"2013","unstructured":"Hemarajata P, Versalovic J (2013) Effects of probiotics on gut microbiota: mechanisms of intestinal immunomodulation and neuromodulation. Therap Adv Gastroenterol 6:39\u201351. https:\/\/doi.org\/10.1177\/1756283X12459294","journal-title":"Therap Adv Gastroenterol"},{"key":"10553_CR73","doi-asserted-by":"publisher","first-page":"1","DOI":"10.3389\/fmicb.2023.1296447","volume":"14","author":"OA Petrariu","year":"2023","unstructured":"Petrariu OA, Barbu IC, Niculescu AG et al (2023) Role of probiotics in managing various human diseases, from oral pathology to cancer and gastrointestinal diseases. Front Microbiol 14:1\u201323. https:\/\/doi.org\/10.3389\/fmicb.2023.1296447","journal-title":"Front Microbiol"},{"issue":"2","key":"10553_CR74","doi-asserted-by":"publisher","first-page":"234","DOI":"10.3390\/microorganisms12020234","volume":"12","author":"N-M Maftei","year":"2024","unstructured":"Maftei N-M, Raileanu CR, Balta AA et al (2024) The potential impact of probiotics on human health: an update on their health-promoting properties. Microorganisms 12(2):234. https:\/\/doi.org\/10.3390\/microorganisms12020234","journal-title":"Microorganisms"},{"key":"10553_CR75","doi-asserted-by":"publisher","first-page":"4948","DOI":"10.1111\/ijfs.16619","volume":"58","author":"SA Ibrahim","year":"2023","unstructured":"Ibrahim SA, Yeboah PJ, Ayivi RD et al (2023) A review and comparative perspective on health benefits of probiotic and fermented foods. Int J Food Sci Technol 58:4948\u20134964. https:\/\/doi.org\/10.1111\/ijfs.16619","journal-title":"Int J Food Sci Technol"},{"key":"10553_CR76","doi-asserted-by":"crossref","unstructured":"Prajapati J, Nair B (2003) The history of fermented foods in fermented functional foods. Handb fermented foods 1\u201325","DOI":"10.1201\/9780203009727.ch1"},{"key":"10553_CR77","doi-asserted-by":"publisher","first-page":"1328620","DOI":"10.3389\/fnut.2024.1328620","volume":"11","author":"GN Saleem","year":"2024","unstructured":"Saleem GN, Gu R, Qu H et al (2024) Therapeutic potential of popular fermented dairy products and its benefits on human health. Front Nutr 11:1328620. https:\/\/doi.org\/10.3389\/fnut.2024.1328620","journal-title":"Front Nutr"},{"issue":"1","key":"10553_CR78","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s42779-024-00241-7","volume":"11","author":"R Surya","year":"2024","unstructured":"Surya R (2024) Fermented foods of Southeast Asia other than soybean- or seafood-based ones. J Ethn Foods 11(1):27. https:\/\/doi.org\/10.1186\/s42779-024-00241-7","journal-title":"J Ethn Foods"},{"key":"10553_CR79","doi-asserted-by":"publisher","unstructured":"Summers WC (2009) History of microbiology. Encycl Microbiol Third Ed 30\u201347. https:\/\/doi.org\/10.1016\/B978-012373944-5.00295-9","DOI":"10.1016\/B978-012373944-5.00295-9"},{"key":"10553_CR80","doi-asserted-by":"publisher","first-page":"959941","DOI":"10.3389\/fnut.2022.959941","volume":"9","author":"M Idrees","year":"2022","unstructured":"Idrees M, Imran M, Atiq N et al (2022) Probiotics, their action modality and the use of multi-omics in metamorphosis of commensal microbiota into target-based probiotics. Front Nutr 9:959941. https:\/\/doi.org\/10.3389\/fnut.2022.959941","journal-title":"Front Nutr"},{"key":"10553_CR81","first-page":"466","volume":"1","author":"K Anukam","year":"2007","unstructured":"Anukam K, Reid G (2007) Probiotics: 100 years (1907\u20132007) after Elie Metchnikoff\u2019s observation. Commun Curr Res Educ Top Trends Appl Microbiol 1:466\u2013474","journal-title":"Commun Curr Res Educ Top Trends Appl Microbiol"},{"key":"10553_CR82","doi-asserted-by":"publisher","unstructured":"Chen W (2019) Lactic acid bacteria: omics and functional evaluation. https:\/\/doi.org\/10.1007\/978-981-13-7832-4","DOI":"10.1007\/978-981-13-7832-4"},{"key":"10553_CR83","doi-asserted-by":"publisher","first-page":"456","DOI":"10.1080\/03036758.2019.1692364","volume":"50","author":"J Crane","year":"2020","unstructured":"Crane J, Barthow C, Kang J et al (2020) Probiotics for humans: hoax, hype, hope, or help. J R Soc New Zeal 50:456\u2013469. https:\/\/doi.org\/10.1080\/03036758.2019.1692364","journal-title":"J R Soc New Zeal"},{"issue":"1","key":"10553_CR84","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1186\/s42269-023-01098-7","volume":"47","author":"D Singh","year":"2023","unstructured":"Singh D, Singh A, Kumar S (2023) Probiotics: friend or foe to the human immune system. Bull Natl Res Cent 47(1):126. https:\/\/doi.org\/10.1186\/s42269-023-01098-7","journal-title":"Bull Natl Res Cent"},{"key":"10553_CR85","doi-asserted-by":"publisher","first-page":"100185","DOI":"10.1016\/j.afres.2022.100185","volume":"2","author":"TK Das","year":"2022","unstructured":"Das TK, Pradhan S, Chakrabarti S et al (2022) Current status of probiotic and related health benefits. Appl Food Res 2:100185. https:\/\/doi.org\/10.1016\/j.afres.2022.100185","journal-title":"Appl Food Res"},{"key":"10553_CR86","doi-asserted-by":"publisher","first-page":"127336","DOI":"10.1016\/j.micres.2023.127336","volume":"270","author":"Y Qi","year":"2023","unstructured":"Qi Y, Yu L, Tian F et al (2023) In vitro models to study human gut-microbiota interactions: applications, advances, and limitations. Microbiol Res 270:127336. https:\/\/doi.org\/10.1016\/j.micres.2023.127336","journal-title":"Microbiol Res"},{"key":"10553_CR87","doi-asserted-by":"publisher","first-page":"117207","DOI":"10.1016\/j.biopha.2024.117207","volume":"178","author":"S Lu","year":"2024","unstructured":"Lu S, Zhao Q, Guan Y et al (2024) The communication mechanism of the gut-brain axis and its effect on central nervous system diseases: a systematic review. Biomed Pharmacother 178:117207. https:\/\/doi.org\/10.1016\/j.biopha.2024.117207","journal-title":"Biomed Pharmacother"},{"key":"10553_CR88","doi-asserted-by":"publisher","first-page":"87","DOI":"10.1016\/j.carbpol.2017.06.119","volume":"175","author":"P Singh","year":"2017","unstructured":"Singh P, Medronho B, Alves L et al (2017) Development of carboxymethyl cellulose-chitosan hybrid micro- and macroparticles for encapsulation of probiotic bacteria. Carbohydr Polym 175:87\u201395. https:\/\/doi.org\/10.1016\/j.carbpol.2017.06.119","journal-title":"Carbohydr Polym"},{"key":"10553_CR89","doi-asserted-by":"publisher","first-page":"106337","DOI":"10.1016\/j.jff.2024.106337","volume":"119","author":"O Victoria Obayomi","year":"2024","unstructured":"Victoria Obayomi O, FolakemiOlaniran A, OlugbemigaOwa S (2024) Unveiling the role of functional foods with emphasis on prebiotics and probiotics in human health: a review. J Funct Foods 119:106337. https:\/\/doi.org\/10.1016\/j.jff.2024.106337","journal-title":"J Funct Foods"},{"key":"10553_CR90","doi-asserted-by":"publisher","first-page":"e35980","DOI":"10.1016\/j.heliyon.2024.e35980","volume":"10","author":"T Jan","year":"2024","unstructured":"Jan T, Negi R, Sharma B et al (2024) Next generation probiotics for human health: an emerging perspective. Heliyon 10:e35980. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e35980","journal-title":"Heliyon"},{"key":"10553_CR91","doi-asserted-by":"publisher","first-page":"8411","DOI":"10.1007\/s00253-021-11622-2","volume":"105","author":"Y Ding","year":"2021","unstructured":"Ding Y, Bu F, Chen T et al (2021) A next-generation probiotic: Akkermansia muciniphila ameliorates chronic stress\u2013induced depressive-like behavior in mice by regulating gut microbiota and metabolites. Appl Microbiol Biotechnol 105:8411\u20138426. https:\/\/doi.org\/10.1007\/s00253-021-11622-2","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"10553_CR92","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1038\/s41522-024-00571-z","volume":"10","author":"Y Zhang","year":"2024","unstructured":"Zhang Y, Li X, Lu S et al (2024) Stress triggers gut dysbiosis via CRH-CRHR1-mitochondria pathway. npj Biofilms Microbiomes 10(1):93. https:\/\/doi.org\/10.1038\/s41522-024-00571-z","journal-title":"npj Biofilms Microbiomes"},{"key":"10553_CR93","doi-asserted-by":"publisher","first-page":"187","DOI":"10.1016\/j.jad.2022.02.024","volume":"303","author":"F Gao","year":"2022","unstructured":"Gao F, Guo R, Ma Q et al (2022) Stressful events induce long-term gut microbiota dysbiosis and associated post-traumatic stress symptoms in healthcare workers fighting against COVID-19. J Affect Disord 303:187\u2013195. https:\/\/doi.org\/10.1016\/j.jad.2022.02.024","journal-title":"J Affect Disord"},{"key":"10553_CR94","doi-asserted-by":"publisher","first-page":"1365871","DOI":"10.3389\/fimmu.2024.1365871","volume":"15","author":"A Warren","year":"2024","unstructured":"Warren A, Nyavor Y, Beguelin A, Frame LA (2024) Dangers of the chronic stress response in the context of the microbiota-gut-immune-brain axis and mental health: a narrative review. Front Immunol 15:1365871. https:\/\/doi.org\/10.3389\/fimmu.2024.1365871","journal-title":"Front Immunol"},{"issue":"9","key":"10553_CR95","doi-asserted-by":"publisher","first-page":"e70043","DOI":"10.7759\/cureus.70043","volume":"16","author":"M Meenatchi","year":"2024","unstructured":"Meenatchi M, Vellapandian C (2024) Exploring the long-term effect of artificial sweeteners on metabolic health. Cureus 16(9):e70043. https:\/\/doi.org\/10.7759\/cureus.70043","journal-title":"Cureus"},{"key":"10553_CR96","doi-asserted-by":"publisher","first-page":"518","DOI":"10.1002\/jpen.1861","volume":"45","author":"C Tan","year":"2021","unstructured":"Tan C, Wu Q, Wang H et al (2021) Dysbiosis of gut microbiota and short-chain fatty acids in acute ischemic stroke and the subsequent risk for poor functional outcomes. JPEN J Parenter Enteral Nutr 45:518\u2013529. https:\/\/doi.org\/10.1002\/jpen.1861","journal-title":"JPEN J Parenter Enteral Nutr"},{"issue":"6","key":"10553_CR97","doi-asserted-by":"publisher","first-page":"738","DOI":"10.1038\/mp.2016.50","volume":"21","author":"GB Rogers","year":"2016","unstructured":"Rogers GB, Keating DJ, Young RL et al (2016) From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways. Mol Psychiatry 21(6):738\u2013748. https:\/\/doi.org\/10.1038\/mp.2016.50","journal-title":"Mol Psychiatry"},{"key":"10553_CR98","doi-asserted-by":"publisher","first-page":"109951","DOI":"10.1016\/j.pnpbp.2020.109951","volume":"102","author":"B Misiak","year":"2020","unstructured":"Misiak B, \u0141oniewski I, Marlicz W et al (2020) The HPA axis dysregulation in severe mental illness: can we shift the blame to gut microbiota? Prog Neuro-Psychopharmacol Biol Psychiatry 102:109951. https:\/\/doi.org\/10.1016\/j.pnpbp.2020.109951","journal-title":"Prog Neuro-Psychopharmacol Biol Psychiatry"},{"key":"10553_CR99","doi-asserted-by":"publisher","first-page":"604179","DOI":"10.3389\/fimmu.2020.604179","volume":"11","author":"A Rutsch","year":"2020","unstructured":"Rutsch A, Kantsj\u00f6 JB, Ronchi F (2020) The gut-brain axis: how microbiota and host inflammasome influence brain physiology and pathology. Front Immunol 11:604179. https:\/\/doi.org\/10.3389\/fimmu.2020.604179","journal-title":"Front Immunol"},{"issue":"16","key":"10553_CR100","doi-asserted-by":"publisher","first-page":"5231","DOI":"10.3390\/jcm12165231","volume":"12","author":"TS Chaudhry","year":"2023","unstructured":"Chaudhry TS, Senapati SG, Gadam S et al (2023) The impact of microbiota on the gut\u2013brain axis: examining the complex interplay and implications. J Clin Med 12(16):5231. https:\/\/doi.org\/10.3390\/jcm12165231","journal-title":"J Clin Med"},{"key":"10553_CR101","doi-asserted-by":"publisher","first-page":"47","DOI":"10.3390\/applmicrobiol4010004","volume":"4","author":"RS Aleman","year":"2024","unstructured":"Aleman RS, Yadav A (2024) Systematic review of probiotics and their potential for developing functional nondairy foods. Appl Microbiol 4:47\u201369. https:\/\/doi.org\/10.3390\/applmicrobiol4010004","journal-title":"Appl Microbiol"},{"key":"10553_CR102","doi-asserted-by":"publisher","first-page":"S49","DOI":"10.1093\/advances\/nmy063","volume":"10","author":"J Plaza-Diaz","year":"2019","unstructured":"Plaza-Diaz J, Ruiz-Ojeda FJ, Gil-Campos M, Gil A (2019) Mechanisms of action of probiotics. Adv Nutr 10:S49\u2013S66. https:\/\/doi.org\/10.1093\/advances\/nmy063","journal-title":"Adv Nutr"},{"issue":"11","key":"10553_CR103","doi-asserted-by":"publisher","first-page":"6022","DOI":"10.3390\/ijms25116022","volume":"25","author":"P Chandrasekaran","year":"2024","unstructured":"Chandrasekaran P, Weiskirchen S, Weiskirchen R (2024) Effects of probiotics on gut microbiota: an overview. Int J Mol Sci 25(11):6022. https:\/\/doi.org\/10.3390\/ijms25116022","journal-title":"Int J Mol Sci"},{"issue":"20","key":"10553_CR104","doi-asserted-by":"publisher","first-page":"4466","DOI":"10.3390\/nu15204466","volume":"15","author":"Y Shin","year":"2023","unstructured":"Shin Y, Han S, Kwon J et al (2023) Roles of short-chain fatty acids in inflammatory bowel disease. Nutrients 15(20):4466. https:\/\/doi.org\/10.3390\/nu15204466","journal-title":"Nutrients"},{"key":"10553_CR105","doi-asserted-by":"publisher","first-page":"634897","DOI":"10.3389\/fnut.2021.634897","volume":"8","author":"Y Liu","year":"2021","unstructured":"Liu Y, Wang J, Wu C (2021) Modulation of gut microbiota and immune system by probiotics, pre-biotics, and post-biotics. Front Nutr 8:634897. https:\/\/doi.org\/10.3389\/fnut.2021.634897","journal-title":"Front Nutr"},{"key":"10553_CR106","doi-asserted-by":"publisher","first-page":"1167116","DOI":"10.3389\/fcimb.2023.1167116","volume":"13","author":"J Gao","year":"2023","unstructured":"Gao J, Zhao L, Cheng Y et al (2023) Probiotics for the treatment of depression and its comorbidities: a systemic review. Front Cell Infect Microbiol 13:1167116. https:\/\/doi.org\/10.3389\/fcimb.2023.1167116","journal-title":"Front Cell Infect Microbiol"},{"key":"10553_CR107","doi-asserted-by":"publisher","first-page":"1277","DOI":"10.1007\/s10620-019-05777-2","volume":"65","author":"D Hollander","year":"2020","unstructured":"Hollander D, Kaunitz JD (2020) The \u201cleaky gut\u201d: tight junctions but loose associations? Dig Dis Sci 65:1277\u20131287. https:\/\/doi.org\/10.1007\/s10620-019-05777-2","journal-title":"Dig Dis Sci"},{"key":"10553_CR108","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1002\/1873-3468.14328","volume":"596","author":"AE Mohr","year":"2022","unstructured":"Mohr AE, Crawford M, Jasbi P et al (2022) Lipopolysaccharide and the gut microbiota: considering structural variation. FEBS Lett 596:849\u2013875. https:\/\/doi.org\/10.1002\/1873-3468.14328","journal-title":"FEBS Lett"},{"key":"10553_CR109","doi-asserted-by":"publisher","first-page":"503","DOI":"10.3988\/jcn.2021.17.4.503","volume":"17","author":"KM Han","year":"2021","unstructured":"Han KM, Ham BJ (2021) How inflammation affects the brain in depression: a review of functional and structural MRI studies. J Clin Neurol 17:503\u2013515. https:\/\/doi.org\/10.3988\/jcn.2021.17.4.503","journal-title":"J Clin Neurol"},{"issue":"13","key":"10553_CR110","doi-asserted-by":"publisher","first-page":"6729","DOI":"10.3390\/ijms22136729","volume":"22","author":"EC Rose","year":"2021","unstructured":"Rose EC, Odle J, Blikslager AT, Ziegler AL (2021) Probiotics, prebiotics and epithelial tight junctions: a promising approach to modulate intestinal barrier function. Int J Mol Sci 22(13):6729. https:\/\/doi.org\/10.3390\/ijms22136729","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10553_CR111","doi-asserted-by":"publisher","first-page":"e00308","DOI":"10.14309\/ctg.0000000000000308","volume":"12","author":"M Camilleri","year":"2021","unstructured":"Camilleri M (2021) Human intestinal barrier: effects of stressors, diet, prebiotics, and probiotics. Clin Transl Gastroenterol 12(1):e00308","journal-title":"Clin Transl Gastroenterol"},{"key":"10553_CR112","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1007\/s12602-017-9322-6","volume":"10","author":"G La Fata","year":"2018","unstructured":"La Fata G, Weber P, Mohajeri MH (2018) Probiotics and the gut immune system: indirect regulation. Probiotics Antimicrob Proteins 10:11\u201321. https:\/\/doi.org\/10.1007\/s12602-017-9322-6","journal-title":"Probiotics Antimicrob Proteins"},{"key":"10553_CR113","doi-asserted-by":"publisher","first-page":"1143548","DOI":"10.3389\/fimmu.2023.1143548","volume":"14","author":"Y Zheng","year":"2023","unstructured":"Zheng Y, Zhang Z, Tang P et al (2023) Probiotics fortify intestinal barrier function: a systematic review and meta-analysis of randomized trials. Front Immunol 14:1143548. https:\/\/doi.org\/10.3389\/fimmu.2023.1143548","journal-title":"Front Immunol"},{"key":"10553_CR114","doi-asserted-by":"publisher","first-page":"1205","DOI":"10.1016\/j.biopha.2018.05.086","volume":"105","author":"F Mumtaz","year":"2018","unstructured":"Mumtaz F, Khan MI, Zubair M, Dehpour AR (2018) Neurobiology and consequences of social isolation stress in animal model\u2014a comprehensive review. Biomed Pharmacother 105:1205\u20131222. https:\/\/doi.org\/10.1016\/j.biopha.2018.05.086","journal-title":"Biomed Pharmacother"},{"key":"10553_CR115","doi-asserted-by":"publisher","first-page":"1098412","DOI":"10.3389\/fmicb.2023.1098412","volume":"14","author":"S Miri","year":"2023","unstructured":"Miri S, Yeo J, Abubaker S, Hammami R (2023) Neuromicrobiology, an emerging neurometabolic facet of the gut microbiome? Front Microbiol 14:1098412. https:\/\/doi.org\/10.3389\/fmicb.2023.1098412","journal-title":"Front Microbiol"},{"issue":"1","key":"10553_CR116","doi-asserted-by":"publisher","first-page":"154","DOI":"10.1186\/s12974-022-02510-1","volume":"19","author":"P Sittipo","year":"2022","unstructured":"Sittipo P, Choi J, Lee S, Lee YK (2022) The function of gut microbiota in immune-related neurological disorders: A review. J Neuroinflammation 19(1):154. https:\/\/doi.org\/10.1186\/s12974-022-02510-1","journal-title":"J Neuroinflammation"},{"key":"10553_CR117","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.jtcme.2022.03.001","volume":"13","author":"A Mehra","year":"2023","unstructured":"Mehra A, Arora G, Sahni G et al (2023) Gut microbiota and autism spectrum disorder: from pathogenesis to potential therapeutic perspectives. J Tradit Complement Med 13:135\u2013149. https:\/\/doi.org\/10.1016\/j.jtcme.2022.03.001","journal-title":"J Tradit Complement Med"},{"key":"10553_CR118","doi-asserted-by":"publisher","first-page":"106952","DOI":"10.1016\/j.phrs.2023.106952","volume":"197","author":"S Parolisi","year":"2023","unstructured":"Parolisi S, Montanari C, Borghi E et al (2023) Possible role of tryptophan metabolism along the microbiota-gut-brain axis on cognitive & behavioral aspects in phenylketonuria. Pharmacol Res 197:106952. https:\/\/doi.org\/10.1016\/j.phrs.2023.106952","journal-title":"Pharmacol Res"},{"key":"10553_CR119","doi-asserted-by":"publisher","first-page":"1348297","DOI":"10.3389\/fphar.2024.1348297","volume":"15","author":"A Kumar","year":"2024","unstructured":"Kumar A, Sivamaruthi BS, Dey S et al (2024) Probiotics as modulators of gut-brain axis for cognitive development. Frontiers in Pharmacology 15:1348297. https:\/\/doi.org\/10.3389\/fphar.2024.1348297","journal-title":"Frontiers in Pharmacology"},{"key":"10553_CR120","doi-asserted-by":"publisher","first-page":"1434","DOI":"10.3390\/cimb44040096","volume":"44","author":"F-M Tette","year":"2022","unstructured":"Tette F-M, Kwofie SK, Wilson MD (2022) Therapeutic anti-depressant potential of microbial GABA produced by Lactobacillus rhamnosus strains for GABAergic signaling restoration and inhibition of addiction-induced HPA axis hyperactivity. Curr Issues Mol Biol 44:1434\u20131451. https:\/\/doi.org\/10.3390\/cimb44040096","journal-title":"Curr Issues Mol Biol"},{"issue":"11","key":"10553_CR121","doi-asserted-by":"publisher","first-page":"1166","DOI":"10.3390\/metabo13111166","volume":"13","author":"Y Hou","year":"2023","unstructured":"Hou Y, Li J, Ying S (2023) Tryptophan metabolism and gut microbiota: a novel regulatory axis integrating the microbiome, immunity, and cancer. Metabolites 13(11):1166. https:\/\/doi.org\/10.3390\/metabo13111166","journal-title":"Metabolites"},{"key":"10553_CR122","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1093\/advances\/nmz127","volume":"11","author":"K Gao","year":"2020","unstructured":"Gao K, Mu C-L, Farzi A, Zhu W-Y (2020) Tryptophan metabolism: a link between the gut microbiota and brain. Adv Nutr 11:709\u2013723. https:\/\/doi.org\/10.1093\/advances\/nmz127","journal-title":"Adv Nutr"},{"key":"10553_CR123","doi-asserted-by":"publisher","first-page":"e40293","DOI":"10.7759\/cureus.40293","volume":"15","author":"JS Madabushi","year":"2023","unstructured":"Madabushi JS, Khurana P, Gupta N, Gupta M (2023) Gut biome and mental health: do probiotics work? Cureus 15:e40293. https:\/\/doi.org\/10.7759\/cureus.40293","journal-title":"Cureus"},{"key":"10553_CR124","doi-asserted-by":"publisher","first-page":"e08522","DOI":"10.1016\/j.heliyon.2021.e08522","volume":"7","author":"V Agarwal","year":"2021","unstructured":"Agarwal V, Kaushik AS, Rehman M et al (2021) Interleukin-6 expression and its modulation by diacerein in a rat model of chronic stress induced cardiac dysfunction. Heliyon 7:e08522. https:\/\/doi.org\/10.1016\/j.heliyon.2021.e08522","journal-title":"Heliyon"},{"key":"10553_CR125","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1111\/nyas.13217","volume":"1391","author":"JJ Joseph","year":"2017","unstructured":"Joseph JJ, Golden SH (2017) Cortisol dysregulation: the bidirectional link between stress, depression, and type 2 diabetes mellitus. Ann N Y Acad Sci 1391:20\u201334. https:\/\/doi.org\/10.1111\/nyas.13217","journal-title":"Ann N Y Acad Sci"},{"key":"10553_CR126","doi-asserted-by":"publisher","first-page":"100541","DOI":"10.1016\/j.bbih.2022.100541","volume":"26","author":"D Freimer","year":"2022","unstructured":"Freimer D, Yang TT, Ho TC et al (2022) The gut microbiota, HPA axis, and brain in adolescent-onset depression: probiotics as a novel treatment. Brain, Behav Immun - Heal 26:100541. https:\/\/doi.org\/10.1016\/j.bbih.2022.100541","journal-title":"Brain, Behav Immun - Heal"},{"key":"10553_CR127","doi-asserted-by":"publisher","first-page":"138","DOI":"10.5056\/jnm16167","volume":"24","author":"A Ait-Belgnaoui","year":"2018","unstructured":"Ait-Belgnaoui A, Payard I, Rolland C et al (2018) Bifidobacterium longum and lactobacillus helveticus synergistically suppress stress-related visceral hypersensitivity through hypothalamic-pituitary-adrenal axis modulation. J Neurogastroenterol Motil 24:138\u2013146. https:\/\/doi.org\/10.5056\/jnm16167","journal-title":"J Neurogastroenterol Motil"},{"issue":"7","key":"10553_CR128","doi-asserted-by":"publisher","first-page":"1054","DOI":"10.3390\/nu16071054","volume":"16","author":"A Dziedzic","year":"2024","unstructured":"Dziedzic A, Maciak K, Bli\u017aniewska-Kowalska K et al (2024) The power of psychobiotics in depression: a modern approach through the microbiota\u2013gut\u2013brain axis: a literature review. Nutrients 16(7):1054. https:\/\/doi.org\/10.3390\/nu16071054","journal-title":"Nutrients"},{"key":"10553_CR129","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.jpsychires.2023.08.006","volume":"166","author":"X-J Kong","year":"2023","unstructured":"Kong X-J, Kang J, Liu K (2023) Probiotic and intra-nasal oxytocin combination therapy on autonomic function and gut-brain axis signaling in young children and teens with autism spectrum disorder. J Psychiatr Res 166:1\u20139. https:\/\/doi.org\/10.1016\/j.jpsychires.2023.08.006","journal-title":"J Psychiatr Res"},{"key":"10553_CR130","doi-asserted-by":"publisher","first-page":"589","DOI":"10.5056\/jnm16018","volume":"22","author":"H Wang","year":"2016","unstructured":"Wang H, Lee I-S, Braun C, Enck P (2016) Effect of probiotics on central nervous system functions in animals and humans: a systematic review. J Neurogastroenterol Motil 22:589\u2013605. https:\/\/doi.org\/10.5056\/jnm16018","journal-title":"J Neurogastroenterol Motil"},{"key":"10553_CR131","doi-asserted-by":"publisher","first-page":"107541","DOI":"10.1016\/j.phrs.2024.107541","volume":"211","author":"J Feng","year":"2025","unstructured":"Feng J, Cen Q, Cui Y et al (2025) Lactobacillus rhamnosus: an emerging probiotic with therapeutic potential for depression. Pharmacol Res 211:107541. https:\/\/doi.org\/10.1016\/j.phrs.2024.107541","journal-title":"Pharmacol Res"},{"key":"10553_CR132","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.3389\/fnins.2019.01361","volume":"13","author":"SJ Yong","year":"2020","unstructured":"Yong SJ, Tong T, Chew J, Lim WL (2020) Antidepressive mechanisms of probiotics and their therapeutic potential. Front Neurosci 13:1361. https:\/\/doi.org\/10.3389\/fnins.2019.01361","journal-title":"Front Neurosci"},{"key":"10553_CR133","doi-asserted-by":"publisher","first-page":"510","DOI":"10.1111\/nmo.12295","volume":"26","author":"A Ait-Belgnaoui","year":"2014","unstructured":"Ait-Belgnaoui A, Colom A, Braniste V et al (2014) Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice. Neurogastroenterol Motil 26:510\u2013520. https:\/\/doi.org\/10.1111\/nmo.12295","journal-title":"Neurogastroenterol Motil"},{"key":"10553_CR134","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1038\/npp.2015.171","volume":"41","author":"BS McEwen","year":"2016","unstructured":"McEwen BS, Nasca C, Gray JD (2016) Stress effects on neuronal structure: hippocampus, amygdala, and prefrontal cortex. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol 41:3\u201323. https:\/\/doi.org\/10.1038\/npp.2015.171","journal-title":"Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol"},{"key":"10553_CR135","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1016\/j.nbd.2010.04.017","volume":"39","author":"G Issa","year":"2010","unstructured":"Issa G, Wilson C, Terry AVJ, Pillai A (2010) An inverse relationship between cortisol and BDNF levels in schizophrenia: data from human postmortem and animal studies. Neurobiol Dis 39:327\u2013333. https:\/\/doi.org\/10.1016\/j.nbd.2010.04.017","journal-title":"Neurobiol Dis"},{"key":"10553_CR136","doi-asserted-by":"publisher","first-page":"363","DOI":"10.3389\/fncel.2019.00363","volume":"13","author":"M Miranda","year":"2019","unstructured":"Miranda M, Morici JF, Zanoni MB, Bekinschtein P (2019) Brain-derived neurotrophic factor: a key molecule for memory in the healthy and the pathological brain. Front Cell Neurosci 13:363. https:\/\/doi.org\/10.3389\/fncel.2019.00363","journal-title":"Front Cell Neurosci"},{"key":"10553_CR137","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/j.immuni.2019.12.003","volume":"52","author":"C Madore","year":"2020","unstructured":"Madore C, Yin Z, Leibowitz J, Butovsky O (2020) Microglia, Lifestyle Stress, And Neurodegeneration. Immunity 52:222\u2013240. https:\/\/doi.org\/10.1016\/j.immuni.2019.12.003","journal-title":"Immunity"},{"key":"10553_CR138","doi-asserted-by":"publisher","first-page":"117177","DOI":"10.1016\/j.biopha.2024.117177","volume":"178","author":"NK Bhol","year":"2024","unstructured":"Bhol NK, Bhanjadeo MM, Singh AK et al (2024) The interplay between cytokines, inflammation, and antioxidants: mechanistic insights and therapeutic potentials of various antioxidants and anti-cytokine compounds. Biomed Pharmacother 178:117177. https:\/\/doi.org\/10.1016\/j.biopha.2024.117177","journal-title":"Biomed Pharmacother"},{"issue":"3","key":"10553_CR139","doi-asserted-by":"publisher","first-page":"629","DOI":"10.3390\/nu12030629","volume":"12","author":"A Orlando","year":"2020","unstructured":"Orlando A, Chimienti G, Lezza AMS et al (2020) Lactobacillus rhamnosus GG affects the BDNF system in brain samples of Wistar rats with pepsin-trypsin-digested gliadin (PTG)-induced enteropathy. Nutrients 12(3):629. https:\/\/doi.org\/10.3390\/nu12030629","journal-title":"Nutrients"},{"key":"10553_CR140","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.1111\/j.1365-2982.2011.01796.x","volume":"23","author":"P Bercik","year":"2011","unstructured":"Bercik P, Park AJ, Sinclair D et al (2011) The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication. Neurogastroenterol Motil 23:1132\u20131139. https:\/\/doi.org\/10.1111\/j.1365-2982.2011.01796.x","journal-title":"Neurogastroenterol Motil"},{"issue":"1","key":"10553_CR141","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1186\/s12964-023-01219-9","volume":"21","author":"D Zhang","year":"2023","unstructured":"Zhang D, Jian YP, Zhang YN et al (2023) Short-chain fatty acids in diseases. Cell Commun Signal 21(1):212. https:\/\/doi.org\/10.1186\/s12964-023-01219-9","journal-title":"Cell Commun Signal"},{"key":"10553_CR142","doi-asserted-by":"publisher","first-page":"100673","DOI":"10.1016\/j.bbih.2023.100673","volume":"32","author":"SM M\u00e4kel\u00e4","year":"2023","unstructured":"M\u00e4kel\u00e4 SM, Griffin SM, Reimari J et al (2023) Efficacy and safety of Lacticaseibacillus paracasei Lpc-37\u00ae in students facing examination stress: a randomized, triple-blind, placebo-controlled clinical trial (the ChillEx study). Brain, Behav Immun - Heal 32:100673. https:\/\/doi.org\/10.1016\/j.bbih.2023.100673","journal-title":"Brain, Behav Immun - Heal"},{"key":"10553_CR143","doi-asserted-by":"publisher","first-page":"e27908","DOI":"10.1016\/j.heliyon.2024.e27908","volume":"10","author":"X Liu","year":"2024","unstructured":"Liu X, Zhao H, Wong A (2024) Accounting for the health risk of probiotics. Heliyon 10:e27908. https:\/\/doi.org\/10.1016\/j.heliyon.2024.e27908","journal-title":"Heliyon"},{"key":"10553_CR144","doi-asserted-by":"publisher","first-page":"e8860","DOI":"10.7759\/cureus.8860","volume":"12","author":"TGO Achufusi","year":"2020","unstructured":"Achufusi TGO, Sharma A, Zamora EA, Manocha D (2020) Small intestinal bacterial overgrowth: comprehensive review of diagnosis, prevention, and treatment methods. Cureus 12:e8860. https:\/\/doi.org\/10.7759\/cureus.8860","journal-title":"Cureus"},{"key":"10553_CR145","doi-asserted-by":"publisher","first-page":"112376","DOI":"10.1016\/j.bbr.2019.112376","volume":"379","author":"LK Stenman","year":"2020","unstructured":"Stenman LK, Patterson E, Meunier J et al (2020) Strain specific stress-modulating effects of candidate probiotics: a systematic screening in a mouse model of chronic restraint stress. Behav Brain Res 379:112376. https:\/\/doi.org\/10.1016\/j.bbr.2019.112376","journal-title":"Behav Brain Res"},{"key":"10553_CR146","doi-asserted-by":"publisher","first-page":"100919","DOI":"10.1016\/j.focha.2025.100919","volume":"6","author":"AN Mafe","year":"2025","unstructured":"Mafe AN, Edo GI, Majeed OS et al (2025) A review on probiotics and dietary bioactives: insights on metabolic well-being, gut microbiota, and inflammatory responses. Food Chem Adv 6:100919. https:\/\/doi.org\/10.1016\/j.focha.2025.100919","journal-title":"Food Chem Adv"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-025-10553-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-025-10553-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-025-10553-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T12:07:59Z","timestamp":1757160479000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-025-10553-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,26]]},"references-count":146,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["10553"],"URL":"https:\/\/doi.org\/10.1007\/s12602-025-10553-y","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,26]]},"assertion":[{"value":"17 April 2025","order":1,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"26 April 2025","order":2,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"It is a review and no ethical approval is required.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Animal Ethical Approval"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}