{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:22:55Z","timestamp":1787728975600,"version":"build-2784847793"},"reference-count":54,"publisher":"Springer Science and Business Media LLC","issue":"6","license":[{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T00:00:00Z","timestamp":1773705600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100004377","name":"The Hong Kong Polytechnic University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004377","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics & Antimicro. Prot."],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1007\/s12602-026-10983-2","type":"journal-article","created":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T10:35:40Z","timestamp":1773743740000},"page":"7668-7680","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Synergistic Effects of Auranofin and Lysozyme Against Staphylococcus Aureus"],"prefix":"10.1007","volume":"18","author":[{"given":"Qi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachi","family":"Chiou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,3,17]]},"reference":[{"key":"10983_CR1","doi-asserted-by":"publisher","first-page":"105914","DOI":"10.1016\/j.ebiom.2025.105914","volume":"119","author":"Q Zhang","year":"2025","unstructured":"Zhang Q et al (2025) A strategy to re-sensitise drug-resistant Gram-positive bacteria to oxazolidinone-class antibiotics. EBioMedicine 119:105914","journal-title":"EBioMedicine"},{"key":"10983_CR2","doi-asserted-by":"publisher","first-page":"1319","DOI":"10.1016\/S0161-6420(99)00717-4","volume":"106","author":"P Garg","year":"1999","unstructured":"Garg P, Sharma S, Rao GN (1999) Ciprofloxacin-resistant Pseudomonas keratitis. Ophthalmology 106:1319\u20131323","journal-title":"Ophthalmology"},{"key":"10983_CR3","doi-asserted-by":"publisher","first-page":"e02115","DOI":"10.1128\/aem.02115-24","volume":"91","author":"Q Zhang","year":"2025","unstructured":"Zhang Q (2025) Antimicrobial peptides: from discovery to developmental applications. Appl Environ Microbiol 91:e02115\u201302124","journal-title":"Appl Environ Microbiol"},{"key":"10983_CR4","doi-asserted-by":"publisher","first-page":"127983","DOI":"10.1016\/j.micres.2024.127983","volume":"291","author":"Q Zhang","year":"2025","unstructured":"Zhang Q (2025) Structural insights into the advancements of mobile colistin resistance enzymes. Microbiol Res 291:127983","journal-title":"Microbiol Res"},{"key":"10983_CR5","doi-asserted-by":"crossref","unstructured":"Shoaib M et al (2023), MRSA compendium of epidemiology, transmission, pathophysiology, treatment, and prevention within one health framework. Front. Microbiol. 13, 1067284","DOI":"10.3389\/fmicb.2022.1067284"},{"key":"10983_CR6","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1002\/mlf2.12137","volume":"3","author":"K Cheng","year":"2024","unstructured":"Cheng K et al (2024) Staphylococcus aureus SOS response: activation, impact, and drug targets. mLife 3:343\u2013366","journal-title":"mLife"},{"key":"10983_CR7","doi-asserted-by":"publisher","first-page":"5453","DOI":"10.1002\/chem.202004698","volume":"27","author":"Z Zhao","year":"2021","unstructured":"Zhao Z et al (2021) Light-triggered nitric oxide release by a photosensitizer to combat bacterial biofilm infections. Chem Eur J 27:5453\u20135460","journal-title":"Chem Eur J"},{"key":"10983_CR8","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1002\/mlf2.12135","volume":"3","author":"J Wang","year":"2024","unstructured":"Wang J et al (2024) Discovery of \u03b2-nitrostyrene derivatives as potential quorum sensing inhibitors for biofilm inhibition and antivirulence factor therapeutics against Serratia marcescens. mLife 3:445\u2013458","journal-title":"mLife"},{"key":"10983_CR9","doi-asserted-by":"publisher","first-page":"462","DOI":"10.1007\/s00203-024-04188-w","volume":"206","author":"Q Zhang","year":"2024","unstructured":"Zhang Q (2024) Bacteria carrying mobile colistin resistance genes and their control measures, an updated review. Arch Microbiol 206:462","journal-title":"Arch Microbiol"},{"key":"10983_CR10","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1038\/s41586-025-08615-w","volume":"639","author":"K Goldberg","year":"2025","unstructured":"Goldberg K et al (2025) Cell-autonomous innate immunity by proteasome-derived defence peptides. Nature 639:1032\u20131041","journal-title":"Nature"},{"key":"10983_CR11","doi-asserted-by":"publisher","first-page":"94","DOI":"10.3390\/antibiotics8030094","volume":"8","author":"AS Brott","year":"2019","unstructured":"Brott AS, Clarke AJ (2019) Peptidoglycan O-acetylation as a virulence factor: its effect on lysozyme in the innate immune system. Antibiotics 8:94","journal-title":"Antibiotics"},{"key":"10983_CR12","doi-asserted-by":"publisher","first-page":"107523","DOI":"10.1016\/j.ijantimicag.2025.107523","volume":"66","author":"J Yang","year":"2025","unstructured":"Yang J et al (2025) Synergistic activity of menadione in combination with colistin against colistin-susceptible and colistin-resistant Gram-negative bacteria. Int J Antimicrob Agents 66:107523","journal-title":"Int J Antimicrob Agents"},{"key":"10983_CR13","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1007\/s12602-020-09708-w","volume":"13","author":"P Sheoran","year":"2021","unstructured":"Sheoran P, Tiwari SK (2021) Synergistically-acting enterocin LD3 and plantaricin LD4 against Gram-positive and Gram-negative pathogenic bacteria. Probiotics Antimicro 13:542\u2013554","journal-title":"Probiotics Antimicro"},{"key":"10983_CR14","doi-asserted-by":"publisher","first-page":"105186","DOI":"10.1016\/j.ebiom.2024.105186","volume":"105","author":"HY Li","year":"2024","unstructured":"Li HY et al (2024) Clinical efficacy of CDK4\/6 inhibitor plus endocrine therapy in HR-positive\/HER2-0 and HER2-low-positive metastatic breast cancer: a secondary analysis of PALOMA-2 and PALOMA-3 trials. EBioMedicine 105:105186","journal-title":"EBioMedicine"},{"key":"10983_CR15","doi-asserted-by":"crossref","unstructured":"Zhang Q et al (2022), Re-sensitization of mcr carrying multidrug resistant bacteria to colistin by silver. Proc. Natl. Acad. Sci. U.S.A. 119, e2119417119","DOI":"10.1073\/pnas.2119417119"},{"key":"10983_CR16","doi-asserted-by":"publisher","first-page":"5263","DOI":"10.1038\/s41467-020-18939-y","volume":"11","author":"H Sun","year":"2020","unstructured":"Sun H et al (2020) Resensitizing carbapenem- and colistin-resistant bacteria to antibiotics using auranofin. Nat Commun 11:5263","journal-title":"Nat Commun"},{"key":"10983_CR17","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/mlf2.12121","volume":"3","author":"J Li","year":"2024","unstructured":"Li J et al (2024) Cinnamaldehyde targets SarA to enhance \u03b2-lactam antibiotic activity against methicillin-resistant Staphylococcus aureus. mLife 3:291\u2013306","journal-title":"mLife"},{"key":"10983_CR18","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1016\/j.pharmr.2025.100104","volume":"78","author":"CA Roque-Borda","year":"2026","unstructured":"Roque-Borda CA et al (2026) Synergistic combinations of antimicrobial peptides and conventional antibiotics: A strategy to delay resistance emergence in World Health Organization priority bacteria. Pharmacol Rev 78:34","journal-title":"Pharmacol Rev"},{"key":"10983_CR19","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1038\/s41579-019-0159-8","volume":"17","author":"K Bush","year":"2019","unstructured":"Bush K, Bradford PA (2019) Interplay between \u03b2-lactamases and new \u03b2-lactamase inhibitors. Nat Rev Microbiol 17:295\u2013306","journal-title":"Nat Rev Microbiol"},{"key":"10983_CR20","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s00775-022-01983-y","volume":"28","author":"Q Zhang","year":"2023","unstructured":"Zhang Q et al (2023) Gold drugs as colistin adjuvants in the fight against MCR-1 producing bacteria. J Biol Inorg Chem 28:225\u2013234","journal-title":"J Biol Inorg Chem"},{"key":"10983_CR21","doi-asserted-by":"publisher","DOI":"10.1002\/9781119191377","volume-title":"Metals in Medicine","author":"JC Dabrowiak","year":"2017","unstructured":"Dabrowiak JC (2017) Metals in Medicine. John Wiley & Sons, Ltd, West Sussex"},{"key":"10983_CR22","doi-asserted-by":"publisher","first-page":"1749","DOI":"10.1086\/647952","volume":"49","author":"JH Jorgensen","year":"2009","unstructured":"Jorgensen JH, Ferraro MJ (2009) Antimicrobial susceptibility testing: a review of general principles and contemporary practices. Clin Infect Dis 49:1749\u20131755","journal-title":"Clin Infect Dis"},{"key":"10983_CR23","doi-asserted-by":"publisher","first-page":"2100681","DOI":"10.1002\/advs.202100681","volume":"8","author":"S Zhang","year":"2021","unstructured":"Zhang S et al (2021) Diclofenac resensitizes methicillin-resistant Staphylococcus aureus to \u03b2-lactams and prevents implant infections. Adv Sci 8:2100681","journal-title":"Adv Sci"},{"key":"10983_CR24","doi-asserted-by":"publisher","first-page":"2003","DOI":"10.1021\/acschembio.2c00011","volume":"17","author":"H Guo","year":"2022","unstructured":"Guo H et al (2022) Integrated mass spectrometry reveals celastrol as a novel catechol-O-methyltransferase inhibitor. ACS Chem Biol 17:2003\u20132009","journal-title":"ACS Chem Biol"},{"key":"10983_CR25","doi-asserted-by":"publisher","first-page":"eadd9280","DOI":"10.1126\/sciadv.add9280","volume":"9","author":"RAG da Silva","year":"2023","unstructured":"da Silva RAG et al (2023) Mitoxantrone targets both host and bacteria to overcome vancomycin resistance in Enterococcus faecalis. Sci Adv 9:eadd9280","journal-title":"Sci Adv"},{"key":"10983_CR26","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1002\/mlf2.12084","volume":"2","author":"X Shen","year":"2023","unstructured":"Shen X et al (2023) Identification of atypical T4SS effector proteins mediating bacterial defense. mLife 2:295\u2013307","journal-title":"mLife"},{"key":"10983_CR27","doi-asserted-by":"publisher","first-page":"2162","DOI":"10.1093\/jac\/dkad207","volume":"78","author":"WJ Cai","year":"2023","unstructured":"Cai WJ, Lu MQ, Dai WJ (2023) Novel antibiotic susceptibility of an RNA polymerase \u03b1-subunit mutant in Pseudomonas aeruginosa. J Antimicrob Chemother 78:2162\u20132169","journal-title":"J Antimicrob Chemother"},{"key":"10983_CR28","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1002\/mlf2.12139","volume":"3","author":"J He","year":"2024","unstructured":"He J et al (2024) EmbB and EmbC regulate the sensitivity of Mycobacterium abscessus to echinomycin. mLife 3:459\u2013470","journal-title":"mLife"},{"key":"10983_CR29","doi-asserted-by":"publisher","first-page":"7459","DOI":"10.1021\/acs.jmedchem.4c03167","volume":"68","author":"T Xu","year":"2025","unstructured":"Xu T et al (2025) Development of membrane-targeting osthole derivatives containing pyridinium quaternary ammonium moieties with potent anti-methicillin-resistant Staphylococcus aureus properties. J Med Chem 68:7459\u20137475","journal-title":"J Med Chem"},{"key":"10983_CR30","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1002\/mlf2.70040","volume":"4","author":"X Chen","year":"2025","unstructured":"Chen X et al (2025) CcpA promotes Staphylococcus aureus virulence by directly controlling staphyloxanthin production. mLife 4:651\u2013663","journal-title":"mLife"},{"key":"10983_CR31","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1128\/spectrum.01464-24","volume":"12","author":"H Balogh","year":"2024","unstructured":"Balogh H et al (2024) Novel anti-virulence compounds disrupt exotoxin expression in MRSA. Microbiol Spectr 12:14","journal-title":"Microbiol Spectr"},{"key":"10983_CR32","doi-asserted-by":"publisher","first-page":"1177","DOI":"10.1128\/AAC.01285-10","volume":"55","author":"DJ Farrell","year":"2011","unstructured":"Farrell DJ, Robbins M, Rhys-Williams W, Love WG (2011) Investigation of the potential for mutational resistance to XF-73, retapamulin, mupirocin, fusidic acid, daptomycin, and vancomycin in methicillin-resistant Staphylococcus aureus isolates during a 55-passage study. Antimicrob Agents Chemother 55:1177\u20131181","journal-title":"Antimicrob Agents Chemother"},{"key":"10983_CR33","doi-asserted-by":"publisher","first-page":"1485","DOI":"10.1056\/NEJMe058023","volume":"352","author":"F Chambers Henry","year":"2005","unstructured":"Chambers Henry F (2005) Community-associated MRSA-resistance and virulence converge. New Engl J Med 352:1485\u20131487","journal-title":"New Engl J Med"},{"key":"10983_CR34","doi-asserted-by":"publisher","first-page":"204ra132","DOI":"10.1126\/scitranslmed.3006609","volume":"5","author":"L Imamovic","year":"2013","unstructured":"Imamovic L, Sommer MOA (2013) Use of collateral sensitivity networks to design drug cycling protocols that avoid resistance development. Sci Transl Med 5:204ra132","journal-title":"Sci Transl Med"},{"key":"10983_CR35","doi-asserted-by":"publisher","first-page":"262ra156","DOI":"10.1126\/scitranslmed.3009940","volume":"6","author":"C Munck","year":"2014","unstructured":"Munck C, Gumpert HK, Wallin AIN, Wang HH, Sommer MOA (2014) Prediction of resistance development against drug combinations by collateral responses to component drugs. Sci Transl Med 6:262ra156","journal-title":"Sci Transl Med"},{"key":"10983_CR36","doi-asserted-by":"publisher","first-page":"819","DOI":"10.3390\/antibiotics11060819","volume":"11","author":"P Gao","year":"2022","unstructured":"Gao P et al (2022) Antivirulence agent as an adjuvant of \u03b2-lactam antibiotics in treating Staphylococcal infections. Antibiotics 11:819","journal-title":"Antibiotics"},{"key":"10983_CR37","doi-asserted-by":"publisher","first-page":"251","DOI":"10.1002\/mlf2.12123","volume":"3","author":"T Wang","year":"2024","unstructured":"Wang T et al (2024) Phage-displayed heptapeptide sequence conjugation significantly improves the specific targeting ability of antimicrobial peptides against Staphylococcus aureus. mLife 3:251\u2013268","journal-title":"mLife"},{"key":"10983_CR38","doi-asserted-by":"crossref","unstructured":"Zhou Y, Ip TK-Y, Zhang Q, Li H, Sun H (2021) Elsevier, Oxford, 9.20 - Metal complexes as drugs and therapeutic agents. in Comprehensive Coordination Chemistry III (eds. Constable, E.C., Parkin, G. & Que Jr, L.) 680\u2013705","DOI":"10.1016\/B978-0-08-102688-5.00018-0"},{"key":"10983_CR39","doi-asserted-by":"publisher","first-page":"102473","DOI":"10.1016\/j.jbc.2022.102473","volume":"298","author":"SPN Tan","year":"2022","unstructured":"Tan SPN, Cho KL, Nodwell JR (2022) A defect in cell wall recycling confers antibiotic resistance and sensitivity in Staphylococcus aureus. J Biol Chem 298:102473","journal-title":"J Biol Chem"},{"key":"10983_CR40","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1111\/j.1574-6976.2007.00099.x","volume":"32","author":"W Vollmer","year":"2008","unstructured":"Vollmer W, Joris B, Charlier P, Foster S (2008) Bacterial peptidoglycan (murein) hydrolases. FEMS Microbiol Rev 32:259\u2013286","journal-title":"FEMS Microbiol Rev"},{"key":"10983_CR41","doi-asserted-by":"publisher","first-page":"3914","DOI":"10.1128\/JB.00207-08","volume":"190","author":"T Uehara","year":"2008","unstructured":"Uehara T, Park JT (2008) Growth of Escherichia coli: significance of peptidoglycan degradation during elongation and septation. J Bacteriol 190:3914\u20133922","journal-title":"J Bacteriol"},{"key":"10983_CR42","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1046\/j.1365-2958.2001.02499.x","volume":"41","author":"C Heidrich","year":"2001","unstructured":"Heidrich C et al (2001) Involvement of N-acetylmuramyl-L-alanine amidases in cell separation and antibiotic-induced autolysis of Escherichia coli. Mol Microbiol 41:167\u2013178","journal-title":"Mol Microbiol"},{"key":"10983_CR43","doi-asserted-by":"publisher","first-page":"1307","DOI":"10.1111\/j.1365-2958.2008.06483.x","volume":"70","author":"S Dubrac","year":"2008","unstructured":"Dubrac S, Bisicchia P, Devine KM, Msadek T (2008) A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway. Mol Microbiol 70:1307\u20131322","journal-title":"Mol Microbiol"},{"key":"10983_CR44","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1038\/ja.2013.33","volume":"66","author":"M Igarashi","year":"2013","unstructured":"Igarashi M et al (2013) Waldiomycin, a novel WalK-histidine kinase inhibitor from Streptomyces sp. MK844-mF10. J Antibiot 66:459\u2013464","journal-title":"J Antibiot"},{"key":"10983_CR45","doi-asserted-by":"publisher","first-page":"1178","DOI":"10.3389\/fimmu.2019.01178","volume":"10","author":"HG Hanstock","year":"2019","unstructured":"Hanstock HG, Edwards JP, Walsh NP (2019) Tear lactoferrin and lysozyme as clinically relevant biomarkers of mucosal immune competence. Front Immunol 10:1178","journal-title":"Front Immunol"},{"key":"10983_CR46","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.mib.2013.11.004","volume":"17","author":"M Otto","year":"2014","unstructured":"Otto M (2014) Staphylococcus aureus toxins. Curr Opin Microbiol 17:32\u201337","journal-title":"Curr Opin Microbiol"},{"key":"10983_CR47","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1126\/science.abl5997","volume":"373","author":"JH Kwon","year":"2021","unstructured":"Kwon JH, Powderly WG (2021) The post-antibiotic era is here. Science 373:471","journal-title":"Science"},{"key":"10983_CR48","doi-asserted-by":"publisher","first-page":"101","DOI":"10.1002\/mlf2.12114","volume":"3","author":"N Tang","year":"2024","unstructured":"Tang N et al (2024) Understanding the rapid spread of antimicrobial resistance genes mediated by IS26. mLife 3:101\u2013109","journal-title":"mLife"},{"key":"10983_CR49","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1038\/sj.eye.6700566","volume":"17","author":"JM Tiffany","year":"2003","unstructured":"Tiffany JM (2003) Tears in health and disease. Eye 17:923\u2013926","journal-title":"Eye"},{"key":"10983_CR50","doi-asserted-by":"publisher","first-page":"e130","DOI":"10.1016\/S2214-109X(20)30425-3","volume":"9","author":"RRA Bourne","year":"2021","unstructured":"Bourne RRA et al (2021) Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the global burden of disease study. Lancet Glob Health 9:e130\u2013e143","journal-title":"Lancet Glob Health"},{"key":"10983_CR51","doi-asserted-by":"publisher","first-page":"55","DOI":"10.3390\/antibiotics10121534","volume":"10","author":"P Ferraboschi","year":"2021","unstructured":"Ferraboschi P, Ciceri S, Grisenti P (2021) Applications of lysozyme, an innate immune defense factor, as an alternative antibiotic. Antibiotics 10:55","journal-title":"Antibiotics"},{"key":"10983_CR52","doi-asserted-by":"publisher","first-page":"997","DOI":"10.1021\/acsmedchemlett.7b00162","volume":"8","author":"T Marzo","year":"2017","unstructured":"Marzo T et al (2017) Et3PAuCl, and Et3PAuI are highly cytotoxic on colorectal cancer cells: a chemical and biological study. ACS Med Chem Lett 8:997\u20131001Auranofin","journal-title":"ACS Med Chem Lett"},{"key":"10983_CR53","first-page":"432","volume":"14","author":"W Jielian","year":"2017","unstructured":"Jielian W, Baoqing H, Chungen W, Peipei Y (2017) Characterization and roles of lysozyme in molluscs. ISJ-Invert Surviv J 14:432\u2013442","journal-title":"ISJ-Invert Surviv J"},{"key":"10983_CR54","first-page":"21","volume":"62","author":"J Liu","year":"2021","unstructured":"Liu J et al (2021) Retinal pigment epithelial cells express antimicrobial peptide lysozyme -a novel mechanism of innate immune defense of the blood-retina barrier. Invest Ophthalmol Vis Sci 62:21\u201321","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-10983-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-026-10983-2","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-10983-2.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:02:10Z","timestamp":1787727730000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-026-10983-2"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,17]]},"references-count":54,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["10983"],"URL":"https:\/\/doi.org\/10.1007\/s12602-026-10983-2","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,17]]},"assertion":[{"value":"26 October 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 March 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"17 March 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"This article does not contain any studies with human participants or animals performed by any of the authors.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Qian Zhao and Qi Zhang have filed a patent application (US application No. 18\/888,874) related to the work presented in this manuscript. All other authors declare no conflict of interest.","order":2,"name":"Ethics","label":"Competing Interests","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Qian Zhao and Qi Zhang have filed a patent application (US application No. 18\/888,874) related to the work presented in this manuscript. All other authors declare no conflict of interest.","order":3,"name":"Ethics","label":"Conflict of interest","group":{"name":"EthicsHeading","label":"Declarations"}}]}}