{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T08:18:54Z","timestamp":1787732334011,"version":"build-2784847793"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","issue":"7","license":[{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:00:00Z","timestamp":1778544000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"crossref","award":["lzujbky-2025-26"],"award-info":[{"award-number":["lzujbky-2025-26"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key R&D Program of Gansu Province","award":["23ZDKA0007"],"award-info":[{"award-number":["23ZDKA0007"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics & Antimicro. Prot."],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1007\/s12602-026-11043-5","type":"journal-article","created":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:38:15Z","timestamp":1778575095000},"page":"8755-8771","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lactiplantibacillus plantarum AS21 Reduces Colitis in Mice by Modulating Inflammation, Gut Barrier Function, and Microbiota in an Intervention Dose and Time-dependent Manner"],"prefix":"10.1007","volume":"18","author":[{"given":"Ali Sher","family":"Bacha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengyan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zitong","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengya","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikram","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Ishaq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azmat Ullah","family":"Jan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashiq","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xusheng","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,5,12]]},"reference":[{"key":"11043_CR1","doi-asserted-by":"publisher","first-page":"1526","DOI":"10.3390\/ijms24021526","volume":"24","author":"A Saez","year":"2023","unstructured":"Saez A, Herrero-Fernandez B, Gomez-Bris R et al (2023) Pathophysiology of Inflammatory Bowel Disease: Innate Immune System. Int J Mol Sci 24:1526. https:\/\/doi.org\/10.3390\/ijms24021526","journal-title":"Int J Mol Sci"},{"key":"11043_CR2","unstructured":"Kemos P (2024) Developing a database and geostatistical methods to study the epidemiology of PIBD. Thesis, Queen Mary University of London"},{"key":"11043_CR3","doi-asserted-by":"publisher","first-page":"1023","DOI":"10.1038\/s41590-025-02197-5","volume":"26","author":"K Cadwell","year":"2025","unstructured":"Cadwell K, Loke P (2025) Gene-environment interactions shape the host-microbial interface in inflammatory bowel disease. Nat Immunol 26:1023\u20131035. https:\/\/doi.org\/10.1038\/s41590-025-02197-5","journal-title":"Nat Immunol"},{"key":"11043_CR4","doi-asserted-by":"publisher","first-page":"5382","DOI":"10.1007\/s10620-022-07719-x","volume":"67","author":"AK Turbayne","year":"2022","unstructured":"Turbayne AK, Sparrow MP (2022) Low-Dose Azathioprine in Combination with Allopurinol: The Past, Present and Future of This Useful Duo. Dig Dis Sci 67:5382\u20135391. https:\/\/doi.org\/10.1007\/s10620-022-07719-x","journal-title":"Dig Dis Sci"},{"key":"11043_CR5","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.3390\/ijms27031534","volume":"27","author":"A Wilk","year":"2026","unstructured":"Wilk A, Paw\u0142owski M, Balcerczak E et al (2026) Advances in the Treatment of Ulcerative Colitis\u2014From Conventional Therapies to Targeted Biologics and Small Molecules. Int J Mol Sci 27:1534. https:\/\/doi.org\/10.3390\/ijms27031534","journal-title":"Int J Mol Sci"},{"key":"11043_CR6","doi-asserted-by":"publisher","first-page":"469","DOI":"10.1007\/s10620-024-08764-4","volume":"70","author":"K Fansiwala","year":"2025","unstructured":"Fansiwala K, Sauk JS (2025) Small molecules, big results: how JAK inhibitors have transformed the treatment of patients with IBD. Dig Dis Sci 70:469\u2013477. https:\/\/doi.org\/10.1007\/s10620-024-08764-4","journal-title":"Dig Dis Sci"},{"key":"11043_CR7","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1016\/j.gie.2018.09.045","volume":"89","author":"B Shen","year":"2019","unstructured":"Shen B, Kochhar G, Navaneethan U et al (2019) Role of interventional inflammatory bowel disease in the era of biologic therapy: a position statement from the Global Interventional IBD Group. Gastrointest Endosc 89:215\u2013237. https:\/\/doi.org\/10.1016\/j.gie.2018.09.045","journal-title":"Gastrointest Endosc"},{"key":"11043_CR8","doi-asserted-by":"publisher","first-page":"221","DOI":"10.3390\/gastroent15010016","volume":"15","author":"GP Venkatesh","year":"2024","unstructured":"Venkatesh GP, Kuruvalli G, Syed K et al (2024) An Updated Review on Probiotic Production and Applications. Gastroenterol Insights 15:221\u2013236. https:\/\/doi.org\/10.3390\/gastroent15010016","journal-title":"Gastroenterol Insights"},{"key":"11043_CR9","doi-asserted-by":"publisher","first-page":"10730","DOI":"10.1080\/10408398.2023.2227896","volume":"64","author":"MM Abedin","year":"2024","unstructured":"Abedin MM, Chourasia R, Phukon LC et al (2024) Lactic acid bacteria in the functional food industry: biotechnological properties and potential applications. Crit Rev Food Sci Nutr 64:10730\u201310748. https:\/\/doi.org\/10.1080\/10408398.2023.2227896","journal-title":"Crit Rev Food Sci Nutr"},{"key":"11043_CR10","doi-asserted-by":"publisher","first-page":"463","DOI":"10.1134\/S0026261722601439","volume":"91","author":"AL Bryukhanov","year":"2022","unstructured":"Bryukhanov AL, Klimko AI, Netrusov AI (2022) Antioxidant Properties of Lactic Acid Bacteria. Microbiology 91:463\u2013478. https:\/\/doi.org\/10.1134\/S0026261722601439","journal-title":"Microbiology"},{"key":"11043_CR11","doi-asserted-by":"publisher","first-page":"72","DOI":"10.1186\/s12951-025-03141-3","volume":"23","author":"A Chen","year":"2025","unstructured":"Chen A, Gong Y, Wu S et al (2025) Navigating a challenging path: precision disease treatment with tailored oral nano-armor-probiotics. J Nanobiotechnol 23:72. https:\/\/doi.org\/10.1186\/s12951-025-03141-3","journal-title":"J Nanobiotechnol"},{"key":"11043_CR12","doi-asserted-by":"publisher","first-page":"2022","DOI":"10.1039\/d3fo05337g","volume":"15","author":"W Li","year":"2024","unstructured":"Li W, Zhang Y, Chen M et al (2024) The antioxidant strain Lactiplantibacillus plantarum AS21 and Clostridium butyricum ameliorate DSS-induced colitis in mice by remodeling the assembly of intestinal microbiota and improving gut functions. Food Funct 15:2022\u20132037. https:\/\/doi.org\/10.1039\/d3fo05337g","journal-title":"Food Funct"},{"key":"11043_CR13","doi-asserted-by":"publisher","first-page":"e0145723","DOI":"10.1128\/spectrum.01457-23","volume":"11","author":"J Liu","year":"2023","unstructured":"Liu J, Fang H, Hong N et al (2023) Gut Microbiome and Metabonomic Profile Predict Early Remission to Anti-Integrin Therapy in Patients with Moderate to Severe Ulcerative Colitis. Microbiol Spectr 11:e0145723. https:\/\/doi.org\/10.1128\/spectrum.01457-23","journal-title":"Microbiol Spectr"},{"key":"11043_CR14","doi-asserted-by":"publisher","first-page":"1996","DOI":"10.1007\/s10753-015-0180-7","volume":"38","author":"J B\u00e1b\u00ed\u010dkov\u00e1","year":"2015","unstructured":"B\u00e1b\u00ed\u010dkov\u00e1 J, T\u00f3thov\u00e1 \u013d, Lengyelov\u00e1 E et al (2015) Sex differences in experimentally induced colitis in mice: a role for estrogens. Inflammation 38:1996\u20132006. https:\/\/doi.org\/10.1007\/s10753-015-0180-7","journal-title":"Inflammation"},{"key":"11043_CR15","doi-asserted-by":"publisher","first-page":"196","DOI":"10.4143\/crt.2022.080","volume":"55","author":"C-H Song","year":"2023","unstructured":"Song C-H, Kim N, Nam RH et al (2023) Changes in gut microbiome upon orchiectomy and testosterone administration in AOM\/DSS-induced colon cancer mouse model. Cancer Res Treat Off J Korean Cancer Assoc 55:196\u2013218. https:\/\/doi.org\/10.4143\/crt.2022.080","journal-title":"Cancer Res Treat Off J Korean Cancer Assoc"},{"key":"11043_CR16","unstructured":"Tshikudi DM (2025) Characterization of the effect of the lack of chromogranin A and pancreastatin inhibition on colonic epithelial barrier integrity and function in male and female mice during colitis. http:\/\/hdl.handle.net\/1993\/39207"},{"key":"11043_CR17","doi-asserted-by":"publisher","first-page":"226","DOI":"10.1186\/s12866-025-03878-9","volume":"25","author":"I Khan","year":"2025","unstructured":"Khan I, Khan I, Xie P et al (2025) Insights into the blood, gut, and oral microbiomes in Chinese patients with myocardial infarction: a case-control study. BMC Microbiol 25:226. https:\/\/doi.org\/10.1186\/s12866-025-03878-9","journal-title":"BMC Microbiol"},{"key":"11043_CR18","doi-asserted-by":"publisher","first-page":"253","DOI":"10.5009\/gnl240146","volume":"19","author":"SJ Oh","year":"2025","unstructured":"Oh SJ, Choi CH, Jung S-A et al (2025) Anxiety and Depression Are Associated with Poor Long-term Quality of Life in Moderate-to-Severe Ulcerative Colitis: Results of a 3-Year Longitudinal Study of the MOSAIK Cohort. Gut Liver 19:253\u2013264. https:\/\/doi.org\/10.5009\/gnl240146","journal-title":"Gut Liver"},{"key":"11043_CR19","doi-asserted-by":"publisher","first-page":"969","DOI":"10.3390\/pharmaceutics15030969","volume":"15","author":"AE Levine","year":"2023","unstructured":"Levine AE, Mark D, Smith L et al (2023) Pharmacologic Management of Monogenic and Very Early Onset Inflammatory Bowel Diseases. Pharmaceutics 15:969. https:\/\/doi.org\/10.3390\/pharmaceutics15030969","journal-title":"Pharmaceutics"},{"key":"11043_CR20","doi-asserted-by":"publisher","first-page":"2705","DOI":"10.7150\/jca.73130","volume":"13","author":"R Caccialanza","year":"2022","unstructured":"Caccialanza R, Cotogni P, Cereda E et al (2022) Nutritional Support in Cancer patients: update of the Italian Intersociety Working Group practical recommendations. J Cancer 13:2705\u20132716. https:\/\/doi.org\/10.7150\/jca.73130","journal-title":"J Cancer"},{"key":"11043_CR21","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1016\/j.jff.2017.06.008","volume":"35","author":"W Ding","year":"2017","unstructured":"Ding W, Wang L, Zhang J et al (2017) Characterization of antioxidant properties of lactic acid bacteria isolated from spontaneously fermented yak milk in the Tibetan Plateau. J Funct Foods 35:481\u2013488. https:\/\/doi.org\/10.1016\/j.jff.2017.06.008","journal-title":"J Funct Foods"},{"key":"11043_CR22","doi-asserted-by":"publisher","first-page":"3690","DOI":"10.1039\/D1FO03538J","volume":"13","author":"W Li","year":"2022","unstructured":"Li W, Gao L, Huang W et al (2022) Antioxidant properties of lactic acid bacteria isolated from traditional fermented yak milk and their probiotic effects on the oxidative senescence of Caenorhabditis elegans. Food Funct 13:3690\u20133703. https:\/\/doi.org\/10.1039\/D1FO03538J","journal-title":"Food Funct"},{"key":"11043_CR23","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.1039\/d2fo02523j","volume":"14","author":"Z Zhou","year":"2023","unstructured":"Zhou Z, He W, Tian H et al (2023) Thyme (Thymus vulgaris L.) polyphenols ameliorate DSS-induced ulcerative colitis of mice by mitigating intestinal barrier damage, regulating gut microbiota, and suppressing TLR4\/NF-\u03baB-NLRP3 inflammasome pathways. Food Funct 14:1113\u20131132. https:\/\/doi.org\/10.1039\/d2fo02523j","journal-title":"Food Funct"},{"key":"11043_CR24","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1038\/s41575-022-00675-x","volume":"19","author":"JK Gustafsson","year":"2022","unstructured":"Gustafsson JK, Johansson MEV (2022) The role of goblet cells and mucus in intestinal homeostasis. Nat Rev Gastroenterol Hepatol 19:785\u2013803. https:\/\/doi.org\/10.1038\/s41575-022-00675-x","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"11043_CR25","doi-asserted-by":"publisher","first-page":"6014706","DOI":"10.1155\/2023\/6014706","volume":"2023","author":"K Mohideen","year":"2023","unstructured":"Mohideen K, Chandrasekar K, Ramsridhar S et al (2023) Assessment of Oxidative Stress by the Estimation of Lipid Peroxidation Marker Malondialdehyde (MDA) in Patients with Chronic Periodontitis: A Systematic Review and Meta-Analysis. Int J Dent 2023:6014706. https:\/\/doi.org\/10.1155\/2023\/6014706","journal-title":"Int J Dent"},{"key":"11043_CR26","doi-asserted-by":"publisher","first-page":"1385","DOI":"10.3390\/antiox12071385","volume":"12","author":"A Golubkova","year":"2023","unstructured":"Golubkova A, Leiva T, Snyder K et al (2023) Response of the Glutathione (GSH) Antioxidant Defense System to Oxidative Injury in Necrotizing Enterocolitis. Antioxid Basel Switz 12:1385. https:\/\/doi.org\/10.3390\/antiox12071385","journal-title":"Antioxid Basel Switz"},{"key":"11043_CR27","doi-asserted-by":"publisher","first-page":"1307394","DOI":"10.3389\/fmed.2024.1307394","volume":"11","author":"I Aggeletopoulou","year":"2024","unstructured":"Aggeletopoulou I, Kalafateli M, Tsounis EP, Triantos C (2024) Exploring the role of IL-1\u03b2 in inflammatory bowel disease pathogenesis. Front Med 11:1307394. https:\/\/doi.org\/10.3389\/fmed.2024.1307394","journal-title":"Front Med"},{"key":"11043_CR28","doi-asserted-by":"publisher","first-page":"15","DOI":"10.61474\/ncs.2024.00052","volume":"3","author":"B Peng","year":"2025","unstructured":"Peng B, Wang X, Tang T et al (2025) The ROS\/NLRP3 Axis in Autophagy Regulation: Implications for Inflammatory Bowel Disease Pathogenesis and Therapy. Nat Cell Sci 3:15\u201326. https:\/\/doi.org\/10.61474\/ncs.2024.00052","journal-title":"Nat Cell Sci"},{"key":"11043_CR29","doi-asserted-by":"publisher","unstructured":"Gryaznova M, Burakova I, Smirnova Y et al (2024) Effect of Probiotic Bacteria on the Gut Microbiome of Mice with Lipopolysaccharide-Induced Inflammation. https:\/\/doi.org\/10.3390\/microorganisms12071341. Microorganisms 12:","DOI":"10.3390\/microorganisms12071341"},{"key":"11043_CR30","doi-asserted-by":"publisher","first-page":"947313","DOI":"10.3389\/fimmu.2022.947313","volume":"13","author":"J Hu","year":"2022","unstructured":"Hu J, Cheng S, Yao J et al (2022) Correlation between altered gut microbiota and elevated inflammation markers in patients with Crohn\u2019s disease. Front Immunol 13:947313. https:\/\/doi.org\/10.3389\/fimmu.2022.947313","journal-title":"Front Immunol"},{"key":"11043_CR31","doi-asserted-by":"publisher","first-page":"681","DOI":"10.1007\/s12602-024-10370-9","volume":"17","author":"MA Tufail","year":"2025","unstructured":"Tufail MA, Schmitz RA (2025) Exploring the Probiotic Potential of Bacteroides spp. Within One Health Paradigm. Probiotics Antimicrob Proteins 17:681\u2013704. https:\/\/doi.org\/10.1007\/s12602-024-10370-9","journal-title":"Probiotics Antimicrob Proteins"},{"key":"11043_CR32","doi-asserted-by":"publisher","first-page":"793","DOI":"10.3390\/cells12050793","volume":"12","author":"J Wang","year":"2023","unstructured":"Wang J, Zhu N, Su X et al (2023) Gut-Microbiota-Derived Metabolites Maintain Gut and Systemic Immune Homeostasis. Cells 12:793. https:\/\/doi.org\/10.3390\/cells12050793","journal-title":"Cells"},{"key":"11043_CR33","doi-asserted-by":"publisher","first-page":"4149","DOI":"10.3390\/ijms11104149","volume":"11","author":"H Schneider","year":"2010","unstructured":"Schneider H, Braun A, F\u00fcllekrug J et al (2010) Lipid Based Therapy for Ulcerative Colitis\u2014Modulation of Intestinal Mucus Membrane Phospholipids as a Tool to Influence Inflammation. Int J Mol Sci 11:4149\u20134164. https:\/\/doi.org\/10.3390\/ijms11104149","journal-title":"Int J Mol Sci"},{"key":"11043_CR34","doi-asserted-by":"publisher","unstructured":"Li W, Zhang G, Fang Y et al (2025) Exploring the potential association and experimental validation of disrupted circadian rhythms with polycystic ovary syndrome via meta-analysis and bioinformatics: a possible pathogenic mechanism. Front Endocrinol 16. https:\/\/doi.org\/10.3389\/fendo.2025.1545789","DOI":"10.3389\/fendo.2025.1545789"},{"key":"11043_CR35","doi-asserted-by":"publisher","first-page":"1574887","DOI":"10.3389\/fphar.2025.1574887","volume":"16","author":"L Wen","year":"2025","unstructured":"Wen L, Yang K, Wang J et al (2025) Gut microbiota-mitochondrial crosstalk in obesity: novel mechanistic insights and therapeutic strategies with traditional Chinese medicine. Front Pharmacol 16:1574887. https:\/\/doi.org\/10.3389\/fphar.2025.1574887","journal-title":"Front Pharmacol"},{"key":"11043_CR36","doi-asserted-by":"publisher","unstructured":"Zhang X, Liu L, Niu P et al (2025) Promoting cytidine biosynthesis by modulating pyrimidine metabolism and carbon metabolic regulatory networks in Bacillus subtilis. Microb Cell Factories 24. https:\/\/doi.org\/10.1186\/s12934-025-02731-y","DOI":"10.1186\/s12934-025-02731-y"},{"key":"11043_CR37","doi-asserted-by":"publisher","first-page":"2507","DOI":"10.3390\/microorganisms10122507","volume":"10","author":"J Fu","year":"2022","unstructured":"Fu J, Zheng Y, Gao Y, Xu W (2022) Dietary Fiber Intake and Gut Microbiota in Human Health. Microorganisms 10:2507. https:\/\/doi.org\/10.3390\/microorganisms10122507","journal-title":"Microorganisms"},{"key":"11043_CR38","doi-asserted-by":"publisher","first-page":"2143","DOI":"10.4014\/jmb.2407.07039","volume":"34","author":"UY Choi","year":"2024","unstructured":"Choi UY, Lee SH (2024) Understanding Metabolic Pathway Rewiring by Oncogenic Gamma Herpesvirus. J Microbiol Biotechnol 34:2143\u20132152. https:\/\/doi.org\/10.4014\/jmb.2407.07039","journal-title":"J Microbiol Biotechnol"},{"key":"11043_CR39","doi-asserted-by":"publisher","first-page":"3556","DOI":"10.1080\/10408398.2022.2132377","volume":"64","author":"Y Wang","year":"2024","unstructured":"Wang Y, Ai Z, Xing X et al (2024) The ameliorative effect of probiotics on diet-induced lipid metabolism disorders: A review. Crit Rev Food Sci Nutr 64:3556\u20133572. https:\/\/doi.org\/10.1080\/10408398.2022.2132377","journal-title":"Crit Rev Food Sci Nutr"},{"key":"11043_CR40","doi-asserted-by":"publisher","unstructured":"Yan Y, Dong L, Xu J et al (2024) Preliminary study on the potential impact of probiotic combination therapy on Helicobacter pylori infection in children using 16S gene sequencing and untargeted metabolomics approach. Front Microbiol 15. https:\/\/doi.org\/10.3389\/fmicb.2024.1487978","DOI":"10.3389\/fmicb.2024.1487978"},{"key":"11043_CR41","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1038\/s41420-024-02180-3","volume":"10","author":"W Zhu","year":"2024","unstructured":"Zhu W, Zhou Y, Guo L, Feng S (2024) Biological function of sialic acid and sialylation in human health and disease. Cell Death Discov 10:415. https:\/\/doi.org\/10.1038\/s41420-024-02180-3","journal-title":"Cell Death Discov"},{"key":"11043_CR42","doi-asserted-by":"publisher","first-page":"6215573","DOI":"10.1155\/2022\/6215573","volume":"2022","author":"X Zhang","year":"2022","unstructured":"Zhang X, Chen D, Xu K, Ma Z (2022) Deciphering the Metabolomics-Based Intervention of Yanghe Decoction on Hashimoto\u2019s Thyroiditis. Evid-Based Complement Altern Med ECAM 2022:6215573. https:\/\/doi.org\/10.1155\/2022\/6215573","journal-title":"Evid-Based Complement Altern Med ECAM"},{"key":"11043_CR43","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/s13213-024-01765-8","volume":"74","author":"Q Liu","year":"2024","unstructured":"Liu Q (2024) Fenofibrate alleviates the composition and metabolic pathways of gut microbiota in high-fat diet treated hamsters. Ann Microbiol 74:21. https:\/\/doi.org\/10.1186\/s13213-024-01765-8","journal-title":"Ann Microbiol"},{"key":"11043_CR44","doi-asserted-by":"publisher","first-page":"347","DOI":"10.1038\/s41579-022-00833-7","volume":"21","author":"G Caballero-Flores","year":"2023","unstructured":"Caballero-Flores G, Pickard JM, N\u00fa\u00f1ez G (2023) Microbiota-mediated colonization resistance: mechanisms and regulation. Nat Rev Microbiol 21:347\u2013360. https:\/\/doi.org\/10.1038\/s41579-022-00833-7","journal-title":"Nat Rev Microbiol"},{"key":"11043_CR45","doi-asserted-by":"publisher","first-page":"116330","DOI":"10.1016\/j.jep.2023.116330","volume":"309","author":"Y Wang","year":"2023","unstructured":"Wang Y, Shao Z, Song C et al (2023) Clinopodium chinense Kuntze ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by reducing systematic inflammation and regulating metabolism. J Ethnopharmacol 309:116330. https:\/\/doi.org\/10.1016\/j.jep.2023.116330","journal-title":"J Ethnopharmacol"},{"key":"11043_CR46","doi-asserted-by":"publisher","first-page":"4485","DOI":"10.1111\/ijfs.16253","volume":"58","author":"F Casciano","year":"2023","unstructured":"Casciano F, Nissen L, Chiarello E et al (2023) In vitro assessment of the effect of lactose-free milk on colon microbiota of lactose-intolerant adults. Int J Food Sci Technol 58:4485\u20134494","journal-title":"Int J Food Sci Technol"},{"key":"11043_CR47","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s12229-020-09231-1","volume":"87","author":"P Garcia-Caparros","year":"2021","unstructured":"Garcia-Caparros P, De Filippis L, Gul A et al (2021) Oxidative stress and antioxidant metabolism under adverse environmental conditions: a review. Bot Rev 87:421\u2013466. https:\/\/doi.org\/10.1007\/s12229-020-09231-1","journal-title":"Bot Rev"},{"key":"11043_CR48","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s43556-025-00301-7","volume":"6","author":"Z Zhang","year":"2025","unstructured":"Zhang Z, Hong W, Zhang Y et al (2025) Mucosal immunity and vaccination strategies: current insights and future perspectives. Mol Biomed 6:57. https:\/\/doi.org\/10.1186\/s43556-025-00301-7","journal-title":"Mol Biomed"},{"key":"11043_CR49","doi-asserted-by":"publisher","first-page":"3421","DOI":"10.3390\/nu17193421","volume":"17","author":"X Liang","year":"2025","unstructured":"Liang X, Wang L (2025) The Mediating Role of Bioactive Molecules in Gut Microbiota\u2013Bone Metabolism Crosstalk. Nutrients 17:3421. https:\/\/doi.org\/10.3390\/nu17193421","journal-title":"Nutrients"},{"key":"11043_CR50","doi-asserted-by":"publisher","first-page":"89","DOI":"10.3390\/cimb47020089","volume":"47","author":"K Napi\u00f3rkowska-Baran","year":"2025","unstructured":"Napi\u00f3rkowska-Baran K, Treichel P, Dardzi\u0144ska A et al (2025) Immunomodulatory effects of selected non-nutritive bioactive compounds and their role in optimal nutrition. Curr Issues Mol Biol 47:89. https:\/\/doi.org\/10.3390\/cimb47020089","journal-title":"Curr Issues Mol Biol"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11043-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-026-11043-5","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11043-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:29:59Z","timestamp":1787729399000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-026-11043-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,12]]},"references-count":50,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["11043"],"URL":"https:\/\/doi.org\/10.1007\/s12602-026-11043-5","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,12]]},"assertion":[{"value":"4 February 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"28 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The authors declare no competing interests.","order":1,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}