{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T05:19:20Z","timestamp":1788153560044,"version":"build-2803163510"},"reference-count":63,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics & Antimicro. Prot."],"DOI":"10.1007\/s12602-026-11193-6","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:31:39Z","timestamp":1788150699000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lactobacillus Fermentum MCC2760 Mitigates Oxidized Oil-Induced Metabolic Dysfunction and Gut-liver axis Perturbations: A Two-Generation Study in rats"],"prefix":"10.1007","author":[{"given":"Vyshali Ramesh","family":"Keremane","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamsavi Gopal","family":"Kamala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Komatwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai Kumar","family":"Somashekher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5783-1890","authenticated-orcid":false,"given":"Ramaprasad Ravichandra","family":"Talahalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"key":"11193_CR1","doi-asserted-by":"publisher","first-page":"636","DOI":"10.1016\/j.toxrep.2016.08.003","volume":"3","author":"RP Venkata","year":"2016","unstructured":"Venkata RP, Subramanyam R (2016) Evaluation of the deleterious health effects of consumption of repeatedly heated vegetable oil. Toxicol Rep 3:636\u2013643. https:\/\/doi.org\/10.1016\/j.toxrep.2016.08.003","journal-title":"Toxicol Rep"},{"issue":"1","key":"11193_CR2","doi-asserted-by":"publisher","first-page":"2212","DOI":"10.1186\/s12889-024-19624-1","volume":"24","author":"S Ghosh-Jerath","year":"2024","unstructured":"Ghosh-Jerath S, Khandpur N, Kumar G, Kohli S, Singh M, Bhamra IK, Marrocos-Leite FH, Reddy KS (2024) Mapping ultra-processed foods (UPFs) in India: a formative research study. BMC Public Health 24(1):2212. https:\/\/doi.org\/10.1186\/s12889-024-19624-1","journal-title":"BMC Public Health"},{"issue":"10","key":"11193_CR3","doi-asserted-by":"publisher","first-page":"8424","DOI":"10.3390\/nu7105404","volume":"7","author":"TV Gadiraju","year":"2015","unstructured":"Gadiraju TV, Patel Y, Gaziano JM, Djouss\u00e9 L (2015) Fried food consumption and cardiovascular health: a review of current evidence. Nutrients 7(10):8424\u20138430. https:\/\/doi.org\/10.3390\/nu7105404","journal-title":"Nutrients"},{"issue":"10","key":"11193_CR4","doi-asserted-by":"publisher","first-page":"e70969","DOI":"10.1002\/fsn3.70969","volume":"13","author":"N Bazina","year":"2025","unstructured":"Bazina N, Ahmed T, Almdaaf M, Abu Hallalah HM, Jibia S (2025) Chemical changes in deep-fat frying: reaction mechanisms, oil degradation, and health implications. Food Sci Nutr 13(10):e70969. https:\/\/doi.org\/10.1002\/fsn3.70969","journal-title":"Food Sci Nutr"},{"issue":"6","key":"11193_CR5","doi-asserted-by":"publisher","first-page":"662","DOI":"10.1016\/j.chemphyslip.2012.07.002","volume":"165","author":"Q Zhang","year":"2012","unstructured":"Zhang Q, Saleh AS, Chen J, Shen Q (2012) Chemical alterations taken place during deep-fat frying based on certain reaction products: a review. Chem Phys Lipids 165(6):662\u2013681. https:\/\/doi.org\/10.1016\/j.chemphyslip.2012.07.002","journal-title":"Chem Phys Lipids"},{"issue":"36","key":"11193_CR6","doi-asserted-by":"publisher","first-page":"13483","DOI":"10.1021\/acs.jafc.3c02466","volume":"71","author":"F Gao","year":"2023","unstructured":"Gao F, Guan X, Zhang W, Han T, Liu X, Shi B (2023) Oxidized soybean oil evoked hepatic fatty acid metabolism disturbance in rats and their offspring. J Agric Food Chem 71(36):13483\u201313494. https:\/\/doi.org\/10.1021\/acs.jafc.3c02466","journal-title":"J Agric Food Chem"},{"issue":"1","key":"11193_CR7","doi-asserted-by":"publisher","first-page":"14751","DOI":"10.1038\/s41598-018-32906-0","volume":"8","author":"RA Miranda","year":"2018","unstructured":"Miranda RA, De Almeida MM, Rocha CPDD, de Brito Fassarella L, De Souza LL, Souza AFPD, Andrade CBVD, Fortunato RS, Pazos-Moura CC, Trevenzoli IH (2018) Maternal high-fat diet consumption induces sex-dependent alterations of the endocannabinoid system and redox homeostasis in liver of adult rat offspring. Sci Rep 8(1):14751. https:\/\/doi.org\/10.1038\/s41598-018-32906-0","journal-title":"Sci Rep"},{"issue":"2","key":"11193_CR8","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1007\/s11011-020-00642-y","volume":"36","author":"M Zarei","year":"2021","unstructured":"Zarei M, Uppin V, Acharya P, Talahalli R (2021) Ginger and turmeric lipid-solubles attenuate heated oil-induced oxidative stress in the brain via the upregulation of NRF2 and improve cognitive function in rats. Metab Brain Dis 36(2):225\u2013238. https:\/\/doi.org\/10.1007\/s11011-020-00642-y","journal-title":"Metab Brain Dis"},{"key":"11193_CR9","doi-asserted-by":"publisher","first-page":"100919","DOI":"10.1016\/j.focha.2025.100919","volume":"6","author":"AN Mafe","year":"2025","unstructured":"Mafe AN, Edo GI, Majeed OS, Gaaz TS, Akpoghelie PO, Isoje EF, Igbuku UA, Owheruo JO, Opiti RA, Garba Y, Essaghah AE (2025) A review on probiotics and dietary bioactives: insights on metabolic well-being, gut microbiota, and inflammatory responses. Food Chem Adv 6:100919. https:\/\/doi.org\/10.1016\/j.focha.2025.100919","journal-title":"Food Chem Adv"},{"issue":"11","key":"11193_CR10","doi-asserted-by":"publisher","first-page":"6022","DOI":"10.3390\/ijms25116022","volume":"25","author":"P Chandrasekaran","year":"2024","unstructured":"Chandrasekaran P, Weiskirchen S, Weiskirchen R (2024) Effects of probiotics on gut microbiota: an overview. Int J Mol Sci 25(11):6022. https:\/\/doi.org\/10.3390\/ijms25116022","journal-title":"Int J Mol Sci"},{"key":"11193_CR11","doi-asserted-by":"publisher","unstructured":"Keremane V, Kamala H, Halami P, Talahalli R (2025) Lactobacillus fermentum MCC2760 attenuates neurobehavioral alterations induced by oxidized oils in rats. Metab Brain Dis 40(75). https:\/\/doi.org\/10.1007\/s11011-024-01509-2","DOI":"10.1007\/s11011-024-01509-2"},{"issue":"23","key":"11193_CR12","doi-asserted-by":"publisher","first-page":"2400656","DOI":"10.1002\/mnfr.202400656","volume":"68","author":"VR Keremane","year":"2024","unstructured":"Keremane VR, Yashwanthkumar MH, Uppin V, Halami P, Talahalli RR (2024) Lactobacillus fermentum MCC2760 attenuates heated oil-induced brain oxidative stress and inflammation via modulation of NRF2 and NF\u2010kB in rats. Mol Nutr Food Res 68(23):2400656. https:\/\/doi.org\/10.1002\/mnfr.202400656","journal-title":"Mol Nutr Food Res"},{"key":"11193_CR13","doi-asserted-by":"publisher","first-page":"121563","DOI":"10.1016\/j.lfs.2023.121563","volume":"320","author":"D Nair","year":"2023","unstructured":"Nair D, Zarei M, Halami P, Talahalli R (2023) Lactobacillus fermentum MCC2760 abrogate high-fat induced perturbations in the enterohepatic circulation of bile acids in rats. Life Sci 320:121563. https:\/\/doi.org\/10.1016\/j.lfs.2023.121563","journal-title":"Life Sci"},{"issue":"1340","key":"11193_CR14","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1093\/jn\/107.7.1340","volume":"107","author":"CB Diet","year":"1977","unstructured":"Diet CB, Diet U, Diet NP (1977) Report of the American Institute of Nutrition ad hoc committee on standards for nutritional studies. J Nutr 107(1340):10\u201393. https:\/\/doi.org\/10.1093\/jn\/107.7.1340","journal-title":"J Nutr"},{"key":"11193_CR15","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1016\/j.foodchem.2015.04.023","volume":"185","author":"BM Mehta","year":"2015","unstructured":"Mehta BM, Darji VB, Aparnathi KD (2015) Comparison of five analytical methods for the determination of peroxide value in oxidized ghee. Food Chem 185:449\u2013453. https:\/\/doi.org\/10.1016\/j.foodchem.2015.04.023","journal-title":"Food Chem"},{"issue":"5","key":"11193_CR16","doi-asserted-by":"publisher","first-page":"563","DOI":"10.1007\/s11746-998-0066-z","volume":"75","author":"IH Rukunudin","year":"1998","unstructured":"Rukunudin IH, White PJ, Bern CJ, Bailey TB (1998) A modified method for determining free fatty acids from small soybean oil sample sizes. J Am Oil Chem Soc 75(5):563\u2013568. https:\/\/doi.org\/10.1007\/s11746-998-0066-z","journal-title":"J Am Oil Chem Soc"},{"issue":"3","key":"11193_CR17","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1093\/jaoac\/77.3.674","volume":"77","author":"D Firestone","year":"1994","unstructured":"Firestone D (1994) Determination of the iodine value of oils and fats: summary of collaborative study. J AOAC Int 77(3):674\u2013676. https:\/\/doi.org\/10.1093\/jaoac\/77.3.674","journal-title":"J AOAC Int"},{"issue":"10","key":"11193_CR18","doi-asserted-by":"publisher","first-page":"991","DOI":"10.1007\/s11746-009-1435-y","volume":"86","author":"AS Bhatnagar","year":"2009","unstructured":"Bhatnagar AS, Prasanth Kumar PK, Hemavathy J, Gopala Krishna AG (2009) Fatty acid composition, oxidative stability, and radical scavenging activity of vegetable oil blends with coconut oil. J Am Oil Chem Soc 86(10):991\u2013999. https:\/\/doi.org\/10.1007\/s11746-009-1435-y","journal-title":"J Am Oil Chem Soc"},{"key":"11193_CR19","doi-asserted-by":"publisher","unstructured":"Frankel EN (2005) Methods to Determine Extent of Oxidation. In: Lipid Oxidation Chap. 5, The Oily Press, Bridgwater, England. Lipid oxidation. ed. Frankel, EN 10. https:\/\/doi.org\/10.1533\/9780857097927.99","DOI":"10.1533\/9780857097927.99"},{"issue":"1","key":"11193_CR20","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/s0021-9258(18)64849-5","volume":"226","author":"J Folch","year":"1957","unstructured":"Folch J, Lees M, Stanley GS (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226(1):497\u2013509. https:\/\/doi.org\/10.1016\/s0021-9258(18)64849-5","journal-title":"J Biol Chem"},{"issue":"7","key":"11193_CR21","doi-asserted-by":"publisher","first-page":"1201","DOI":"10.1093\/clinchem\/23.7.1201","volume":"23","author":"B Zak","year":"1977","unstructured":"Zak B (1977) Cholesterol methodologies: a review. Clin Chem 23(7):1201\u20131214. https:\/\/doi.org\/10.1093\/clinchem\/23.7.1201","journal-title":"Clin Chem"},{"issue":"3","key":"11193_CR22","doi-asserted-by":"publisher","first-page":"393","DOI":"10.1016\/0009-8981(68)90041-7","volume":"22","author":"MJ Fletcher","year":"1968","unstructured":"Fletcher MJ (1968) A colorimetric method for estimating serum triglycerides. Clin Chim Acta 22(3):393\u2013397. https:\/\/doi.org\/10.1016\/0009-8981(68)90041-7","journal-title":"Clin Chim Acta"},{"issue":"4","key":"11193_CR23","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1016\/S0022-2275(20)40190-7","volume":"5","author":"WR Morrison","year":"1964","unstructured":"Morrison WR, Smith LM (1964) Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride\u2013methanol. J Lipid Res 5(4):600\u2013608. https:\/\/doi.org\/10.1016\/S0022-2275(20)40190-7","journal-title":"J Lipid Res"},{"issue":"2","key":"11193_CR24","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","volume":"95","author":"H Ohkawa","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K (1979) Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 95(2):351\u2013358. https:\/\/doi.org\/10.1016\/0003-2697(79)90738-3","journal-title":"Anal Biochem"},{"key":"11193_CR25","doi-asserted-by":"publisher","first-page":"69","DOI":"10.1016\/j.ab.2014.04.034","volume":"458","author":"CS Mesquita","year":"2014","unstructured":"Mesquita CS, Oliveira R, Bento F, Geraldo D, Rodrigues JV, Marcos JC (2014) Simplified 2, 4-dinitrophenylhydrazine spectrophotometric assay for quantification of carbonyls in oxidized proteins. Anal Biochem 458:69\u201371. https:\/\/doi.org\/10.1016\/j.ab.2014.04.034","journal-title":"Anal Biochem"},{"key":"11193_CR26","doi-asserted-by":"publisher","unstructured":"Aebi H (1984) [13] Catalase in vitro. In Methods in enzymology (Vol 105, pp 121\u2013126). Academic press. https:\/\/doi.org\/10.1016\/S0076-6879(84)05016-3","DOI":"10.1016\/S0076-6879(84)05016-3"},{"key":"11193_CR27","doi-asserted-by":"publisher","unstructured":"Flohe L (1984) [10] Superoxide dismutase assays. In Methods in enzymology (Vol 105, pp 93\u2013104). Academic press. https:\/\/doi.org\/10.1016\/S0076-6879(84)05013-8","DOI":"10.1016\/S0076-6879(84)05013-8"},{"issue":"4","key":"11193_CR28","doi-asserted-by":"publisher","first-page":"1629","DOI":"10.1016\/S0021-9258(17)35986-0","volume":"261","author":"I Carlberg","year":"1986","unstructured":"Carlberg I, Mannervik B (1986) Reduction of 2, 4, 6-trinitrobenzenesulfonate by glutathione reductase and the effect of NADP\u2009+\u2009on the electron transfer. J Biol Chem 261(4):1629\u20131635. https:\/\/doi.org\/10.1016\/S0021-9258(17)35986-0","journal-title":"J Biol Chem"},{"issue":"4","key":"11193_CR29","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1016\/0305-0491(82)90341-8","volume":"73","author":"ME Tappel","year":"1982","unstructured":"Tappel ME, Chaudiere J, Tappel AL (1982) Glutathione peroxidase activities of animal tissues. Comp Biochem Physiol Part B: Comp Biochem 73(4):945\u2013949. https:\/\/doi.org\/10.1016\/0305-0491(82)90341-8","journal-title":"Comp Biochem Physiol Part B: Comp Biochem"},{"issue":"22","key":"11193_CR30","doi-asserted-by":"publisher","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","volume":"249","author":"WH Habig","year":"1974","unstructured":"Habig WH, Pabst MJ, Jakoby WB (1974) Glutathione S-transferases: the first enzymatic step in mercapturic acid formation. J Biol Chem 249(22):7130\u20137139. https:\/\/doi.org\/10.1016\/S0021-9258(19)42083-8","journal-title":"J Biol Chem"},{"issue":"1","key":"11193_CR31","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","volume":"193","author":"OH Lowry","year":"1951","unstructured":"Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J biol Chem 193(1):265\u2013275. https:\/\/doi.org\/10.1016\/S0021-9258(19)52451-6","journal-title":"J biol Chem"},{"key":"11193_CR32","doi-asserted-by":"publisher","first-page":"1192199","DOI":"10.3389\/fnut.2023.1192199","volume":"10","author":"L Geng","year":"2023","unstructured":"Geng L, Liu K, Zhang H (2023) Lipid oxidation in foods and its implications on proteins. Front Nutr 10:1192199. https:\/\/doi.org\/10.3389\/fnut.2023.1192199","journal-title":"Front Nutr"},{"key":"11193_CR33","doi-asserted-by":"publisher","first-page":"717740","DOI":"10.3389\/fnut.2021.717740","volume":"8","author":"XF Leong","year":"2021","unstructured":"Leong XF (2021) Lipid oxidation products on inflammation-mediated hypertension and atherosclerosis: a mini review. Front Nutr 8:717740. https:\/\/doi.org\/10.3389\/fnut.2021.717740","journal-title":"Front Nutr"},{"issue":"8","key":"11193_CR34","doi-asserted-by":"publisher","first-page":"e0237182","DOI":"10.1371\/journal.pone.0237182","volume":"15","author":"Y Yu","year":"2020","unstructured":"Yu Y, Lu J, Oliphant K, Gupta N, Claud K, Lu L (2020) Maternal administration of probiotics promotes gut development in mouse offsprings. PLoS ONE 15(8):e0237182. https:\/\/doi.org\/10.1371\/journal.pone.0237182","journal-title":"PLoS ONE"},{"issue":"1","key":"11193_CR35","doi-asserted-by":"publisher","first-page":"8178","DOI":"10.1038\/s41598-020-65180-0","volume":"10","author":"J Lu","year":"2020","unstructured":"Lu J, Lu L, Yu Y, Baranowski J, Claud EC (2020) Maternal administration of probiotics promotes brain development and protects offspring\u2019s brain from postnatal inflammatory insults in C57\/BL6J mice. Sci Rep 10(1):8178. https:\/\/doi.org\/10.1038\/s41598-020-65180-0","journal-title":"Sci Rep"},{"issue":"4","key":"11193_CR36","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s13668-022-00429-w","volume":"11","author":"C Cuinat","year":"2022","unstructured":"Cuinat C, Stinson SE, Ward WE, Comelli EM (2022) Maternal intake of probiotics to program offspring health. Curr Nutr Rep 11(4):537\u2013562. https:\/\/doi.org\/10.1007\/s13668-022-00429-w","journal-title":"Curr Nutr Rep"},{"key":"11193_CR37","doi-asserted-by":"publisher","first-page":"100797","DOI":"10.1016\/j.yfrne.2019.100797","volume":"55","author":"E Ja\u0161arevi\u0107","year":"2019","unstructured":"Ja\u0161arevi\u0107 E, Bale TL (2019) Prenatal and postnatal contributions of the maternal microbiome on offspring programming. Front Neuroendocr 55:100797. https:\/\/doi.org\/10.1016\/j.yfrne.2019.100797","journal-title":"Front Neuroendocr"},{"issue":"9","key":"11193_CR38","doi-asserted-by":"publisher","first-page":"1099","DOI":"10.3390\/pathogens10091099","volume":"10","author":"S Kumar","year":"2021","unstructured":"Kumar S, Patel GK, Ghoshal UC (2021) Helicobacter pylori-induced inflammation: possible factors modulating the risk of gastric cancer. Pathogens 10(9):1099. https:\/\/doi.org\/10.3390\/pathogens10091099","journal-title":"Pathogens"},{"key":"11193_CR39","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/j.tifs.2021.09.018","volume":"118","author":"J Wang","year":"2021","unstructured":"Wang J, Han L, Wang D, Sun Y, Huang J, Shahidi F (2021) Stability and stabilization of omega-3 oils: a review. Trends Food Sci Technol 118:17\u201335. https:\/\/doi.org\/10.1016\/j.tifs.2021.09.018","journal-title":"Trends Food Sci Technol"},{"issue":"9","key":"11193_CR40","doi-asserted-by":"publisher","first-page":"919","DOI":"10.1177\/0960327116674530","volume":"36","author":"A Narayanankutty","year":"2017","unstructured":"Narayanankutty A, Manalil JJ, Suseela IM, Ramavarma SK, Mathew SE, Illam SP, Babu TD, Kuzhivelil BT, Raghavamenon AC (2017) Deep fried edible oils disturb hepatic redox equilibrium and heightens lipotoxicity and hepatosteatosis in male Wistar rats. Hum Exp Toxicol 36(9):919\u2013930. https:\/\/doi.org\/10.1177\/0960327116674530","journal-title":"Hum Exp Toxicol"},{"issue":"5","key":"11193_CR41","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1016\/j.jn","volume":"31","author":"BJ Saeedi","year":"2020","unstructured":"Saeedi BJ, Liu KH, Owens JA, Hunter-Chang S, Camacho MC, Eboka RU, Chandrasekharan B, Baker NF, Darby TM, Robinson BS, Jones RM (2020) Gut-resident lactobacilli activate hepatic Nrf2 and protect against oxidative liver injury. Cell Metabol 31(5):956\u2013968. https:\/\/doi.org\/10.1016\/j.jn","journal-title":"Cell Metabol"},{"issue":"4","key":"11193_CR42","first-page":"54","volume":"21","author":"R Pelton","year":"2022","unstructured":"Pelton R (2022) Lactobacillus fermentum ME-3: a breakthrough in glutathione therapy. Integr Medicine: Clinician\u2019s J 21(4):54. https:\/\/pubmed.ncbi.nlm.nih.gov\/36644601\/","journal-title":"Integr Medicine: Clinician\u2019s J"},{"issue":"10","key":"11193_CR43","doi-asserted-by":"publisher","first-page":"1340","DOI":"10.3390\/biomedicines9101340","volume":"9","author":"OV Averina","year":"2021","unstructured":"Averina OV, Poluektova EU, Marsova MV, Danilenko VN (2021) Biomarkers and utility of the antioxidant potential of probiotic lactobacilli and bifidobacteria as representatives of the human gut microbiota. Biomedicines 9(10):1340. https:\/\/doi.org\/10.3390\/biomedicines9101340","journal-title":"Biomedicines"},{"key":"11193_CR44","doi-asserted-by":"publisher","unstructured":"Yu W, Tu Y, Long Z, Liu J, Kong D, Peng J, Wu H, Zheng G, Zhao J, Chen Y, Liu R (2022) Reactive oxygen species bridge the gap between chronic inflammation and tumor development. Oxidative Med Cell Longev 12606928. https:\/\/doi.org\/10.1155\/2022\/2606928","DOI":"10.1155\/2022\/2606928"},{"issue":"3","key":"11193_CR45","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1084\/jem.20102049","volume":"208","author":"AC Bulua","year":"2011","unstructured":"Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, Siegel RM (2011) Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med 208(3):519\u2013533. https:\/\/doi.org\/10.1084\/jem.20102049","journal-title":"J Exp Med"},{"key":"11193_CR46","doi-asserted-by":"publisher","first-page":"100885","DOI":"10.1016\/j.crfs.2024.10","volume":"9","author":"Y Yao","year":"2024","unstructured":"Yao Y, Hong Q, Ding S, Cui J, Li W, Zhang J, Sun Y, Yu Y, Yu M, Mi L, Wang Y (2024) Meta-analysis of the effects of probiotics on hyperlipidemia. Curr Res Food Sci 9:100885. https:\/\/doi.org\/10.1016\/j.crfs.2024.10","journal-title":"Curr Res Food Sci"},{"issue":"4","key":"11193_CR47","doi-asserted-by":"publisher","first-page":"411","DOI":"10.2217\/clp.13","volume":"8","author":"N Santoro","year":"2013","unstructured":"Santoro N, Caprio S, Feldstein AE (2013) Oxidized metabolites of linoleic acid as biomarkers of liver injury in nonalcoholic steatohepatitis. Clin Lipidol 8(4):411\u2013418. https:\/\/doi.org\/10.2217\/clp.13","journal-title":"Clin Lipidol"},{"issue":"11","key":"11193_CR48","doi-asserted-by":"publisher","first-page":"2333","DOI":"10.3390\/microorganisms12112333","volume":"12","author":"M Khalil","year":"2024","unstructured":"Khalil M, Di Ciaula A, Mahdi L, Jaber N, Di Palo DM, Graziani A, Baffy G, Portincasa P (2024) Unraveling the role of the human gut microbiome in health and diseases. Microorganisms 12(11):2333. https:\/\/doi.org\/10.3390\/microorganisms12112333","journal-title":"Microorganisms"},{"issue":"7","key":"11193_CR49","doi-asserted-by":"publisher","first-page":"1613","DOI":"10.3390\/nu11071613","volume":"11","author":"RD Hills","year":"2019","unstructured":"Hills RD, Pontefract BA, Mishcon HR, Black CA, Sutton SC, Theberge CR (2019) Gut microbiome: profound implications for diet and disease. Nutrients 11(7):1613. https:\/\/doi.org\/10.3390\/nu11071613","journal-title":"Nutrients"},{"issue":"9","key":"11193_CR50","doi-asserted-by":"publisher","first-page":"1732","DOI":"10.3390\/antiox11091732","volume":"11","author":"E Kwek","year":"2022","unstructured":"Kwek E, Yan C, Ding H, Hao W, He Z, Ma KY, Liu J, Zhu H, Chen ZY (2022) Effects of thermally-oxidized frying oils (corn oil and lard) on gut microbiota in hamsters. Antioxidants 11(9):1732. https:\/\/doi.org\/10.3390\/antiox11091732","journal-title":"Antioxidants"},{"issue":"6","key":"11193_CR51","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.3390\/microorganisms12061210","volume":"12","author":"L Hu","year":"2024","unstructured":"Hu L, Huang L, Fang Z, Wang C, Luo J, Deng Q, Xu D, Sun L, Gooneratne R (2024) Fried soybean oil causes systemic low-grade inflammation by disrupting the balance of gut microbiota in mice. Microorganisms 12(6):1210. https:\/\/doi.org\/10.3390\/microorganisms12061210","journal-title":"Microorganisms"},{"issue":"11","key":"11193_CR52","doi-asserted-by":"publisher","first-page":"1715","DOI":"10.3390\/microorganisms8111715","volume":"8","author":"S Stojanov","year":"2020","unstructured":"Stojanov S, Berlec A, \u0160trukelj B (2020) The influence of probiotics on the firmicutes\/bacteroidetes ratio in the treatment of obesity and inflammatory bowel disease. Microorganisms 8(11):1715. https:\/\/doi.org\/10.3390\/microorganisms8111715","journal-title":"Microorganisms"},{"issue":"5","key":"11193_CR53","doi-asserted-by":"publisher","first-page":"1137","DOI":"10.1097\/MIB.0000000000000750","volume":"22","author":"AK DeGruttola","year":"2016","unstructured":"DeGruttola AK, Low D, Mizoguchi A, Mizoguchi E (2016) Current understanding of dysbiosis in disease in human and animal models. Inflamm Bowel Dis 22(5):1137\u20131150. https:\/\/doi.org\/10.1097\/MIB.0000000000000750","journal-title":"Inflamm Bowel Dis"},{"key":"11193_CR54","doi-asserted-by":"publisher","first-page":"1498625","DOI":"10.3389\/fphar.2024.1498625","volume":"15","author":"Y Alioui","year":"2024","unstructured":"Alioui Y, Ullah H, Ali S, Rahman MU, Elkharti M, Farooqui NA, Rehman AU, Ilyas M, Alsholi DM, Siddiqi NZ, Ali M (2024) Polysaccharides derived from golden mushroom (Cantharellus cibarius Fr.) modulate gut microbiota and enhance intestinal barrier function to ameliorate dextran sulfate sodium-induced colitis in mice. Front Pharmacol 15:1498625. https:\/\/doi.org\/10.3389\/fphar.2024.1498625","journal-title":"Front Pharmacol"},{"issue":"1","key":"11193_CR55","doi-asserted-by":"publisher","first-page":"473","DOI":"10.1007\/s12672-024-01393-3","volume":"15","author":"J Fu","year":"2024","unstructured":"Fu J, Li G, Li X, Song S, Cheng L, Rui B, Jiang L (2024) Gut commensal Alistipes as a potential pathogenic factor in colorectal cancer. Discover Oncol 15(1):473. https:\/\/doi.org\/10.1007\/s12672-024-01393-3","journal-title":"Discover Oncol"},{"issue":"10","key":"11193_CR56","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1111\/apt.17720","volume":"58","author":"N Faqerah","year":"2023","unstructured":"Faqerah N, Walker D, Gerasimidis K (2023) The complex interplay between diet and Escherichia coli in inflammatory bowel disease. Aliment Pharmacol Ther 58(10):984\u20131004. https:\/\/doi.org\/10.1111\/apt.17720","journal-title":"Aliment Pharmacol Ther"},{"issue":"11","key":"11193_CR57","doi-asserted-by":"publisher","first-page":"7701","DOI":"10.1021\/acsomega.1c0004","volume":"6","author":"MK Palani Kumar","year":"2021","unstructured":"Palani Kumar MK, Halami PM, Serva Peddha M (2021) Effect of Lactobacillus fermentum MCC2760-based probiotic curd on hypercholesterolemic C57BL6 mice. ACS omega 6(11):7701\u20137710. https:\/\/doi.org\/10.1021\/acsomega.1c0004","journal-title":"ACS omega"},{"issue":"3","key":"11193_CR58","doi-asserted-by":"publisher","first-page":"318","DOI":"10.5009\/gnl14344","volume":"9","author":"SM Bennet","year":"2015","unstructured":"Bennet SM, \u00d6hman L, Simr\u00e9n M (2015) Gut microbiota as potential orchestrators of irritable bowel syndrome. Gut Liver 9(3):318. https:\/\/doi.org\/10.5009\/gnl14344","journal-title":"Gut Liver"},{"issue":"1","key":"11193_CR59","doi-asserted-by":"publisher","first-page":"106","DOI":"10.1186\/s12937-025-01124-6","volume":"24","author":"Y Zhao","year":"2025","unstructured":"Zhao Y, Niu X, Zhang Y, Zhao L, Zhang L, He J, Zhang Q, Mao Y, Wang F, Zhao X, Wang R (2025) Impact of supplementing Limosilactobacillus fermentum MN\u2013LF23 on the eradication of Helicobacter pylori with 14\u2013day standard quadruple therapy: a randomized, double\u2013blind, placebo\u2013controlled trial. Nutr J 24(1):106. https:\/\/doi.org\/10.1186\/s12937-025-01124-6","journal-title":"Nutr J"},{"key":"11193_CR60","doi-asserted-by":"publisher","first-page":"1103836","DOI":"10.3389\/fmicb.2022.1103836","volume":"13","author":"V Singh","year":"2023","unstructured":"Singh V, Lee G, Son H, Koh H, Kim ES, Unno T, Shin JH (2023) Butyrate producers, The Sentinel of Gut: their intestinal significance with and beyond butyrate, and prospective use as microbial therapeutics. Front Microbiol 13:1103836. https:\/\/doi.org\/10.3389\/fmicb.2022.1103836","journal-title":"Front Microbiol"},{"issue":"1","key":"11193_CR61","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1186\/s12964-023-01219-9","volume":"21","author":"D Zhang","year":"2023","unstructured":"Zhang D, Jian YP, Zhang YN, Li Y, Gu LT, Sun HH, Liu MD, Zhou HL, Wang YS, Xu ZX (2023) Short-chain fatty acids in diseases. Cell Communication Signal 21(1):212. https:\/\/doi.org\/10.1186\/s12964-023-01219-9","journal-title":"Cell Communication Signal"},{"issue":"1","key":"11193_CR62","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1186\/s13099-024-00632-w","volume":"16","author":"G Huang","year":"2024","unstructured":"Huang G, Zheng Y, Zhang N, Huang G, Zhang W, Li Q, Ren X (2024) Desulfovibrio vulgaris caused gut inflammation and aggravated DSS-induced colitis in C57BL\/6 mice model. Gut pathogens 16(1):39. https:\/\/doi.org\/10.1186\/s13099-024-00632-w","journal-title":"Gut pathogens"},{"issue":"7","key":"11193_CR63","doi-asserted-by":"publisher","first-page":"1772","DOI":"10.3390\/microorganisms11071772","volume":"11","author":"SB Singh","year":"2023","unstructured":"Singh SB, Carroll-Portillo A, Lin HC (2023) Desulfovibrio in the gut: the enemy within? Microorganisms 11(7):1772. https:\/\/doi.org\/10.3390\/microorganisms11071772","journal-title":"Microorganisms"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11193-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-026-11193-6","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11193-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T04:31:49Z","timestamp":1788150709000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-026-11193-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,31]]},"references-count":63,"alternative-id":["11193"],"URL":"https:\/\/doi.org\/10.1007\/s12602-026-11193-6","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,31]]},"assertion":[{"value":"10 June 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"22 August 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"31 August 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"The animal procedures were approved (CFT\/IAEC\/254\/2021) and monitored by the Institutional Animal Care and Use Committee of CSIR-CFTRI, Mysore, India. All the experiments were performed according to the CPCSEA (Committee for Control and Supervision of Experiments on Animals) guidelines (CPCSEA Reg No: 49\/ReBi\/S\/99\/CPCSEA).","order":1,"name":"Ethics","label":"Ethical Approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing Interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}