{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:59:48Z","timestamp":1790193588211,"version":"4.1.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","license":[{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:00:00Z","timestamp":1790121600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Probiotics & Antimicro. Prot."],"DOI":"10.1007\/s12602-026-11217-1","type":"journal-article","created":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T07:01:27Z","timestamp":1790146887000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Biocontrol Potential of Bacillus Amyloliquefaciens JDF-1 Against Aspergillus Flavus During Cigar Tobacco Fermentation: Antifungal Activity, Aflatoxin Suppression, and Metabolomic Associations"],"prefix":"10.1007","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9528-1117","authenticated-orcid":false,"given":"Hui","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuming","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueru","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youguo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiakui","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jilai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yonghe","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-3028-5827","authenticated-orcid":false,"given":"Youbo","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,9,23]]},"reference":[{"issue":"7","key":"11217_CR1","doi-asserted-by":"publisher","first-page":"1734","DOI":"10.3390\/molecules25071734","volume":"25","author":"M Bano\u017ei\u0107","year":"2020","unstructured":"Bano\u017ei\u0107 M, Joki\u0107 S, A\u010dkar \u0110, Bla\u017ei\u0107 M, \u0160ubari\u0107 D (2020) Carbohydrates\u2014key players in tobacco aroma formation and quality determination. Molecules 25(7):1734. https:\/\/doi.org\/10.3390\/molecules25071734","journal-title":"Molecules"},{"issue":"5","key":"11217_CR2","doi-asserted-by":"publisher","first-page":"1301","DOI":"10.1007\/s10895-012-1072-y","volume":"22","author":"LL Chan","year":"2012","unstructured":"Chan LL, Wilkinson AR, Paradis BD, Lai N (2012) Rapid image-based cytometry for comparison of fluorescent viability staining methods. J Fluoresc 22(5):1301\u20131311. https:\/\/doi.org\/10.1007\/s10895-012-1072-y","journal-title":"J Fluoresc"},{"key":"11217_CR3","doi-asserted-by":"publisher","first-page":"101421","DOI":"10.1016\/j.jafr.2024.101421","volume":"18","author":"R Chaudhary","year":"2024","unstructured":"Chaudhary R, Nawaz A, Khattak Z, Butt MA, Fouillaud M, Dufoss\u00e9 L, Mukhtar H (2024) Microbial bio-control agents: A comprehensive analysis on sustainable pest management in agriculture. J Agr Food Res 18:101421. https:\/\/doi.org\/10.1016\/j.jafr.2024.101421","journal-title":"J Agr Food Res"},{"key":"11217_CR4","doi-asserted-by":"publisher","first-page":"222","DOI":"10.3389\/fpls.2012.00222","volume":"3","author":"ML Falcone Ferreyra","year":"2012","unstructured":"Falcone Ferreyra ML, Rius SP, Casati P (2012) Flavonoids: biosynthesis, biological functions, and biotechnological applications. Front Plant Sci 3:222. https:\/\/doi.org\/10.3389\/fpls.2012.00222","journal-title":"Front Plant Sci"},{"key":"11217_CR5","doi-asserted-by":"publisher","first-page":"1399777","DOI":"10.3389\/fmicb.2024.1399777","volume":"15","author":"K Fu","year":"2024","unstructured":"Fu K, Song X, Cui Y, Zhou Q, Yin Y, Zhang J, Su Y (2024) Analyzing the quality differences between healthy and mouldy cigar tobacco leaves during the air-curing process through fungal communities and physicochemical components. Front Microbiol 15:1399777. https:\/\/doi.org\/10.3389\/fmicb.2024.1399777","journal-title":"Front Microbiol"},{"key":"11217_CR6","doi-asserted-by":"publisher","first-page":"1264739","DOI":"10.3389\/fpls.2023.1264739","volume":"14","author":"Z Geng","year":"2023","unstructured":"Geng Z, He P, Gao H, Liu J, Qiu J, Cai B (2023) Aroma precursors of cigars from different tobacco parts and origins, and their correlations with sensory characteristics. Front Plant Sci 14:1264739. https:\/\/doi.org\/10.3389\/fpls.2023.1264739","journal-title":"Front Plant Sci"},{"issue":"8","key":"11217_CR7","doi-asserted-by":"publisher","first-page":"3171","DOI":"10.3390\/su16083171","volume":"16","author":"A Gong","year":"2024","unstructured":"Gong A, Song M, Zhang J (2024) Current strategies in controlling Aspergillus flavus and aflatoxins in grains during storage: a review. Sustainability 16(8):3171. https:\/\/doi.org\/10.3390\/su16083171","journal-title":"Sustainability"},{"key":"11217_CR8","doi-asserted-by":"publisher","first-page":"1138877","DOI":"10.3389\/fmicb.2023.1138877","volume":"14","author":"Y Jia","year":"2023","unstructured":"Jia Y, Liu Y, Hu W, Cai W, Zheng Z, Luo C, Li D (2023) Development of Candida autochthonous starter for cigar fermentation via dissecting the microbiome. Front Microbiol 14:1138877. https:\/\/doi.org\/10.3389\/fmicb.2023.1138877","journal-title":"Front Microbiol"},{"key":"11217_CR9","doi-asserted-by":"publisher","first-page":"1201957","DOI":"10.3389\/fbioe.2023.1201957","volume":"11","author":"Y Jia","year":"2023","unstructured":"Jia Y, Zhou W, Yang Z, Zhou Q, Wang Y, Liu Y, Li D (2023) A critical assessment of the Candida strains isolated from cigar tobacco leaves. Front Bioeng Biotech 11:1201957. https:\/\/doi.org\/10.3389\/fbioe.2023.1201957","journal-title":"Front Bioeng Biotech"},{"key":"11217_CR10","doi-asserted-by":"publisher","first-page":"1230345","DOI":"10.3389\/fmicb.2023.1230345","volume":"14","author":"J Kim","year":"2023","unstructured":"Kim J, Kim JC, Sang MK (2023) Identification of isomeric cyclo (leu-pro) produced by Pseudomonas sesami BC42 and its differential antifungal activities against Colletotrichum orbiculare. Front Microbiol 14:1230345. https:\/\/doi.org\/10.3389\/fmicb.2023.1230345","journal-title":"Front Microbiol"},{"issue":"5","key":"11217_CR11","doi-asserted-by":"publisher","first-page":"278","DOI":"10.1016\/j.micres.2013.02.003","volume":"168","author":"SN Kumar","year":"2013","unstructured":"Kumar SN, Mohandas C, Nambisan B (2013) Purification of an antifungal compound, cyclo (l-Pro-d-Leu) for cereals produced by Bacillus cereus subsp. thuringiensis associated with entomopathogenic nematode. Microbiol Res 168(5):278\u2013288. https:\/\/doi.org\/10.1016\/j.micres.2013.02.003","journal-title":"Microbiol Res"},{"issue":"1","key":"11217_CR12","doi-asserted-by":"publisher","first-page":"505","DOI":"10.1007\/s11104-010-0615-8","volume":"340","author":"C Pliego","year":"2011","unstructured":"Pliego C, Ramos C, de Vicente A, Cazorla FM (2011) Screening for candidate bacterial biocontrol agents against soilborne fungal plant pathogens. Plant Soil 340(1):505\u2013520. https:\/\/doi.org\/10.1007\/s11104-010-0615-8","journal-title":"Plant Soil"},{"key":"11217_CR13","doi-asserted-by":"publisher","first-page":"1481158","DOI":"10.3389\/fmicb.2024.1481158","volume":"15","author":"Y Su","year":"2024","unstructured":"Su Y, Cui Y, Fu K, Bu L, Sun Y, Zhou Q, Song X (2024) Contribution of pectin-degrading bacteria to the quality of cigar fermentation: an analysis based on microbial communities and physicochemical components. Front Microbiol 15:1481158. https:\/\/doi.org\/10.3389\/fmicb.2024.1481158","journal-title":"Front Microbiol"},{"issue":"1","key":"11217_CR14","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1186\/s42483-022-00124-2","volume":"4","author":"B Wang","year":"2022","unstructured":"Wang B, Li L, Lin Y, Shen D, Shao X, Zhong C, Qian G (2022) Targeted isolation of biocontrol agents from plants through phytopathogen co-culture and pathogen enrichment. Phytopathol Res 4(1):19. https:\/\/doi.org\/10.1186\/s42483-022-00124-2","journal-title":"Phytopathol Res"},{"key":"11217_CR15","doi-asserted-by":"publisher","first-page":"128531","DOI":"10.1016\/j.jhazmat.2022.128531","volume":"431","author":"X Wang","year":"2022","unstructured":"Wang X, Zhao Y, Qi X, Zhao T, Wang X, Ma F, Zhang L, Zhang Q, Li P (2022) Quantitative analysis of metabolites in the aflatoxin biosynthesis pathway for early warning of aflatoxin contamination by UHPLC-HRMS combined with QAMS. J Hazard Mater 431:128531. https:\/\/doi.org\/10.1016\/j.jhazmat.2022.128531","journal-title":"J Hazard Mater"},{"issue":"1","key":"11217_CR16","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1186\/s13213-024-01783-6","volume":"74","author":"M Wei","year":"2024","unstructured":"Wei M, Shi Y, Song X, Rong L, Li Z, Li J, Chen B (2024) Microbial community analysis of mildewed cigar tobacco leaves from high-throughput sequencing data. Ann Microbiol 74(1):38. https:\/\/doi.org\/10.1186\/s13213-024-01783-6","journal-title":"Ann Microbiol"},{"issue":"1","key":"11217_CR17","doi-asserted-by":"publisher","first-page":"55","DOI":"10.1007\/s44211-024-00676-7","volume":"41","author":"M Wei","year":"2025","unstructured":"Wei M, Wang Y, Shan Y, Rong L, Zhu L, Guo M, Xiang Y (2025) Characteristic volatile product analysis of mouldy cigar wrapper and filler using gas chromatography\u2013ion mobility spectrometry. Anal Sci 41(1):55\u201362. https:\/\/doi.org\/10.1007\/s44211-024-00676-7","journal-title":"Anal Sci"},{"issue":"2","key":"11217_CR18","doi-asserted-by":"publisher","first-page":"485","DOI":"10.1104\/pp.126.2.485","volume":"126","author":"B Winkel-Shirley","year":"2001","unstructured":"Winkel-Shirley B (2001) Flavonoid biosynthesis. A colourful model for genetics, biochemistry, cell biology, and biotechnology. Plant Physiol 126(2):485\u2013493. https:\/\/doi.org\/10.1104\/pp.126.2.485","journal-title":"Plant Physiol"},{"key":"11217_CR19","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.procbio.2024.07.004","volume":"146","author":"G Wu","year":"2024","unstructured":"Wu G, Zhang M, Liu L, Wang H, Guo D, Shi Y, Wu X (2024) Mildew invasion: deciphering its influence on primary metabolites and microbial dynamics in fermented cigar tobacco ecosystems. Process Biochem 146:128\u2013139. https:\/\/doi.org\/10.1016\/j.procbio.2024.07.004","journal-title":"Process Biochem"},{"key":"11217_CR20","doi-asserted-by":"publisher","first-page":"120005","DOI":"10.1016\/j.indcrop.2024.120005","volume":"222","author":"G Wu","year":"2024","unstructured":"Wu G, Zhang M, Han P, Guo D, Shi Y, Mu D, Wu X (2024) Microbial community succession patterns and metabolite profiles in cigar tobacco during different mildew stages. Ind Crop Prod 222:120005. https:\/\/doi.org\/10.1016\/j.indcrop.2024.120005","journal-title":"Ind Crop Prod"},{"key":"11217_CR21","doi-asserted-by":"publisher","first-page":"1632731","DOI":"10.3389\/fmicb.2025.1632731","volume":"16","author":"Y Yin","year":"2025","unstructured":"Yin Y, Song X, Cui Y, Zhang J, Fu K, Zhou Q, Su Y (2025) Application of starch-degradation bacteria in cigar tobacco leaf fermentation: effects on starch degradation, microbial communities and metabolic pathways. Front Microbiol 16:1632731. https:\/\/doi.org\/10.3389\/fmicb.2025.1632731","journal-title":"Front Microbiol"},{"key":"11217_CR22","doi-asserted-by":"publisher","first-page":"104689","DOI":"10.1016\/j.biocontrol.2021.104689","volume":"160","author":"Q Zhang","year":"2021","unstructured":"Zhang Q, Xing C, Li S, He L, Qu T, Chen X (2021) In vitro antagonism and biocontrol effects of Paenibacillus polymyxa JY1-5 against Botrytis cinerea in tomato. Biol Control 160:104689. https:\/\/doi.org\/10.1016\/j.biocontrol.2021.104689","journal-title":"Biol Control"},{"key":"11217_CR23","doi-asserted-by":"publisher","first-page":"1595849","DOI":"10.3389\/fmicb.2025.1595849","volume":"16","author":"G Zhang","year":"2025","unstructured":"Zhang G, Huang K, Xie Q, Li Q, Li D, Ye C, Hu Q (2025) GC-IMS identification of early-warning biomarkers and fungal community dynamics during cigar tobacco mould process. Front Microbiol 16:1595849. https:\/\/doi.org\/10.3389\/fmicb.2025.1595849","journal-title":"Front Microbiol"},{"key":"11217_CR24","doi-asserted-by":"publisher","first-page":"140805","DOI":"10.1016\/j.foodchem.2024.140805","volume":"461","author":"W Zhao","year":"2024","unstructured":"Zhao W, Ma X, Yan H, Zhang L, Shi W, Zhou Y (2024) Aspergillus flavus and aflatoxins control in long-term storage of food ingredients of Puerh tea, peanut and polished rice. Food Chem 461:140805. https:\/\/doi.org\/10.1016\/j.foodchem.2024.140805","journal-title":"Food Chem"},{"issue":"1","key":"11217_CR25","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1007\/s00253-021-11703-2","volume":"106","author":"J Zhou","year":"2022","unstructured":"Zhou J, Cheng Y, Yu L, Zhang J, Zou X (2022) Characteristics of fungal communities and the sources of mould contamination in mildewed tobacco leaves stored under different climatic conditions. Appl Microbiol Biot 106(1):131\u2013144. https:\/\/doi.org\/10.1007\/s00253-021-11703-2","journal-title":"Appl Microbiol Biot"},{"issue":"1","key":"11217_CR26","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1007\/s00253-023-12882-w","volume":"108","author":"J Zhou","year":"2024","unstructured":"Zhou J, Liu J, Wang D, Ruan Y, Gong S, Gou J, Zou X (2024) Fungal communities are more sensitive to mildew than bacterial communities during tobacco storage processes. Appl Microbiol Biot 108(1):88. https:\/\/doi.org\/10.1007\/s00253-023-12882-w","journal-title":"Appl Microbiol Biot"},{"issue":"6","key":"11217_CR27","doi-asserted-by":"publisher","first-page":"93","DOI":"10.16472\/j.chinatobacco.2022.208","volume":"29","author":"BB Zhu","year":"2023","unstructured":"Zhu BB, Huang K, Xue F, An HY, Ye CW, Li D, Li DL (2023) Isolation and identification of major moulds in handmade cigars and study of their biological characteristics. Acta Tabacaria Sinica 29(6):93\u2013101. https:\/\/doi.org\/10.16472\/j.chinatobacco.2022.208","journal-title":"Acta Tabacaria Sinica"}],"container-title":["Probiotics and Antimicrobial Proteins"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11217-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12602-026-11217-1","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12602-026-11217-1.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T19:03:29Z","timestamp":1790190209000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12602-026-11217-1"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,23]]},"references-count":27,"alternative-id":["11217"],"URL":"https:\/\/doi.org\/10.1007\/s12602-026-11217-1","relation":{},"ISSN":["1867-1306","1867-1314"],"issn-type":[{"value":"1867-1306","type":"print"},{"value":"1867-1314","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,23]]},"assertion":[{"value":"14 July 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 September 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"23 September 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"Not applicable.","order":1,"name":"Ethics","label":"Ethical approval","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}]}}