{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T09:01:51Z","timestamp":1773219711570,"version":"3.50.1"},"reference-count":51,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,4,1]],"date-time":"2011-04-01T00:00:00Z","timestamp":1301616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,22]],"date-time":"2023-12-22T00:00:00Z","timestamp":1703203200000},"content-version":"vor","delay-in-days":4648,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Journal of nutrition, health and aging"],"published-print":{"date-parts":[[2011,4]]},"DOI":"10.1007\/s12603-010-0282-8","type":"journal-article","created":{"date-parts":[[2010,10,7]],"date-time":"2010-10-07T03:52:15Z","timestamp":1286423535000},"page":"304-310","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Association between folate status, diabetes, antihypertensive medication and age-related cataracts in elderly Taiwanese"],"prefix":"10.1016","volume":"15","author":[{"given":"Kuan-Ju","family":"Chen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. -H.","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. -J.","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bi-Fong","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1007\/s12603-010-0282-8_bib1","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/s10384-004-0164-x","article-title":"The current status of visual disability in the elderly population of Taiwan","volume":"49","author":"Tsai","year":"2005","journal-title":"Jpn J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib2","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1001\/archopht.1991.01080020090051","article-title":"The lens opacities case-control study. Risk factors for cataract","volume":"109","author":"Leske","year":"1991","journal-title":"Arch Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib3","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1016\/S0161-6420(96)30593-9","article-title":"Risk factors of age-related maculopathy in a population 70 years of age or older","volume":"103","author":"Hirvela","year":"1996","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib4","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0002-9394(14)76661-9","article-title":"Prevalence of senile cataract, diabetic retinopathy, senile macular degeneration, and open-angle glaucoma in the Framingham eye study","volume":"85","author":"Kini","year":"1978","journal-title":"Am J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib5","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1093\/oxfordjournals.aje.a112428","article-title":"The Framingham Eye Study.1.Outline and major prevalence findings","volume":"106","author":"Kahn","year":"1977","journal-title":"Am J Epidemiol"},{"key":"10.1007\/s12603-010-0282-8_bib6","first-page":"2478","article-title":"Prevalence of the different types of agerelated cataract in an African population","volume":"42","author":"Congdon","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1007\/s12603-010-0282-8_bib7","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1001\/archopht.122.4.487","article-title":"Eye Diseases Research Group. Prevalence of cataract and pseudoaphakia\/aphakia among adults in the United States","volume":"122","author":"Congdon","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib8","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1016\/S0002-9394(14)70223-5","article-title":"Hypertension and lens opacities from the Beaver Dam Eye Study","volume":"119","author":"Klein","year":"1995","journal-title":"Am J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib9","first-page":"1248","article-title":"Selected diseases and risk of cataract in women. A case-control study","volume":"96","author":"Tavani","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib10","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000417021","article-title":"Metabolic and social risk factors in a cataractous population. A case-control study","volume":"17","author":"Minglior","year":"1989","journal-title":"Dev Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib11","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/oxfordjournals.aje.a009364","article-title":"Risk factors for nuclear opalescence in a longitudinal study","volume":"147","author":"Leske","year":"1998","journal-title":"Am J Epidemiol"},{"key":"10.1007\/s12603-010-0282-8_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0161-6420(84)34337-8","article-title":"Visual impairment in diabetes","volume":"91","author":"Klein","year":"1984","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib13","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/0002-9394(81)90293-2","article-title":"Senile lens changes and diabetes in two population studies","volume":"91","author":"Ederer","year":"1981","journal-title":"Am J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib14","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0161-6420(85)33877-0","article-title":"Prevalence of cataracts in a population-base study of persons with diabetes mellitus","volume":"92","author":"Klein","year":"1985","journal-title":"Ophthalmology"},{"issue":"suppl3A","key":"10.1007\/s12603-010-0282-8_bib15","doi-asserted-by":"crossref","first-page":"14S","DOI":"10.1016\/0002-9343(94)90293-3","article-title":"Antioxidants and eye disease","volume":"97","author":"Christen","year":"1994","journal-title":"Am J Med"},{"key":"10.1007\/s12603-010-0282-8_bib16","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1093\/aje\/141.4.322","article-title":"Diet and nuclear lens opacities","volume":"141","author":"Mares-Perlman","year":"1995","journal-title":"Am J Epidemiol"},{"key":"10.1007\/s12603-010-0282-8_bib17","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/S0161-6420(99)00024-X","article-title":"Diet and cataract: The Blue Mountains Eye Study","volume":"107","author":"Cumming","year":"2000","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib18","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/ajcn\/75.3.540","article-title":"Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities","volume":"75","author":"Taylor","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib19","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1016\/S0161-6420(01)00833-8","article-title":"Plasma antioxidant vitamins and carotenoids and age-related cataract","volume":"108","author":"Gale","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib20","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1093\/ajcn\/69.2.272","article-title":"Serum carotenoids and tocopherols and incidence of age-related nuclear cataract","volume":"69","author":"Lyle","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib21","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1093\/ajcn\/70.4.509","article-title":"A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women","volume":"70","author":"Chasan-Taber","year":"1999","journal-title":"Am J Clin Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib22","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.ophtha.2003.04.009","article-title":"Vitamin E supplementation and cataract. Randomized Trial","volume":"111","author":"McNeil","year":"2004","journal-title":"Ophthalmology"},{"issue":"21","key":"10.1007\/s12603-010-0282-8_bib23","doi-asserted-by":"crossref","first-page":"10098","DOI":"10.1016\/S0021-9258(18)61082-8","article-title":"The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells","volume":"262","author":"Heinecke","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1007\/s12603-010-0282-8_bib24","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1093\/ajcn\/73.3.613","article-title":"Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort","volume":"73","author":"Jacques","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib25","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1093\/jn\/132.2.283","article-title":"The relationship between riboflavin and plasma total homocysteine in the Framingham offspring cohort is influenced by folate status and the C677T transition in the methylenetrahydrofolate reductase gene","volume":"132","author":"Jacques","year":"2002","journal-title":"J Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib26","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/0026-0495(87)90043-6","article-title":"Homocysteinemia due to folate deficiency","volume":"36","author":"Kang","year":"1987","journal-title":"Metabolism"},{"issue":"3","key":"10.1007\/s12603-010-0282-8_bib27","first-page":"250","article-title":"Association of B vitamins status and homocysteine levels in elderly Taiwanese","volume":"14","author":"Chen","year":"2005","journal-title":"Asia Pacific Journal of Clinical Nutrition"},{"key":"10.1007\/s12603-010-0282-8_bib28","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0002-9394(01)00922-9","article-title":"Use of vitamin supplements and cataract: the Blue Mountains Eye study","volume":"132","author":"Kuzniarz","year":"2001","journal-title":"Am J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib29","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0161-6420(01)00923-X","article-title":"Homocysteine: a risk factor for retinal venous occlusive disease","volume":"109","author":"Brown","year":"2002","journal-title":"Ophthalmology"},{"key":"10.1007\/s12603-010-0282-8_bib30","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/s12291-008-0057-8","article-title":"Plasma Homocysteine, Folate and Vitamin B12 levels in senile cataract","volume":"76","author":"Sen","year":"2008","journal-title":"Indian Journal of Clinical Biochemistry"},{"key":"10.1007\/s12603-010-0282-8_bib31","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1093\/ajcn\/76.4.897","article-title":"Relation of blood homocysteine and its nutritional determinants to age-related maculopathy in the third National Health and Nutrition Examination Survey","volume":"76","author":"Heuberger","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib32","first-page":"203","article-title":"Elderly Nutrition and Health Survey in Taiwan (1999\u20132000) Research design, methodology and content","volume":"14","author":"Pan","year":"2005","journal-title":"Asia Pac J Clin Nut"},{"key":"10.1007\/s12603-010-0282-8_bib33","first-page":"244","article-title":"Association between dietary folate intake and folate status of elderly Taiwanese","volume":"14","author":"Chen","year":"2005","journal-title":"Asia Pacific Journal of Clinical Nutrition"},{"key":"10.1007\/s12603-010-0282-8_bib34","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1136\/jcp.14.4.335","article-title":"Studies on the folic acid activity of human serum","volume":"14","author":"Waters","year":"1961","journal-title":"J Clin Pathol"},{"key":"10.1007\/s12603-010-0282-8_bib35","series-title":"Laboratory tests for the assessment of nutritional status","first-page":"55","author":"Sauberlich","year":"1973"},{"issue":"suppl11","key":"10.1007\/s12603-010-0282-8_bib36","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1093\/jn\/120.suppl_11.1503","article-title":"Vitmin B-6: A status report","volume":"120","author":"Leklem","year":"1990","journal-title":"J Nutr"},{"key":"10.1007\/s12603-010-0282-8_bib37","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/ajcn\/60.1.2","article-title":"Prevalence of cobalamin deficiency in the Framingham elderly population","volume":"60","author":"Lindenbaum","year":"1994","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"10.1007\/s12603-010-0282-8_bib38","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1001\/archopht.1994.01090130095025","article-title":"Is there evidence of an estrogen effect on age-related lens opacities? The Beaver Dam Eye Study","volume":"112","author":"Klein","year":"1994","journal-title":"Arch Ophthalmol"},{"issue":"3","key":"10.1007\/s12603-010-0282-8_bib39","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1093\/oxfordjournals.aje.a009097","article-title":"Hormone replacement therapy, reproductive factors, and cataract. The Blue Mountains Eye Study","volume":"145","author":"Cumming","year":"1997","journal-title":"Am J Epidemiol"},{"issue":"3","key":"10.1007\/s12603-010-0282-8_bib40","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1016\/S0002-9394(00)00474-8","article-title":"Reproductive exposures, incident age-related cataracts, and age-related maculopathy in women: the beaver dam eye study","volume":"130","author":"Klein","year":"2000","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"10.1007\/s12603-010-0282-8_bib41","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1080\/09286580701585736","article-title":"Prevalence and associated factors of refractive errors among type 2 diabetics in Kinmen, Taiwan","volume":"15","author":"Chen","year":"2008","journal-title":"Ophthalmic Epidemiol"},{"key":"10.1007\/s12603-010-0282-8_bib42","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/S1047-2797(00)00178-2","article-title":"A prospective study of blood pressure and risk of cataract in men","volume":"11","author":"Schaumberg","year":"2001","journal-title":"Ann Epidemiol"},{"issue":"2","key":"10.1007\/s12603-010-0282-8_bib43","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1046\/j.1365-2362.1997.780629.x","article-title":"Oxidative protein damage in human diabetic eye: evidence of a retinal participation","volume":"27","author":"Altomare","year":"1997","journal-title":"Eur J Clin Invest"},{"issue":"12","key":"10.1007\/s12603-010-0282-8_bib44","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1016\/S0891-5849(02)01109-7","article-title":"Effect of high-glucose levels on protein oxidation in cultured lens cells, and in crystalline and albumin solution and its inhibition by vitamin B6 and N-acetylcysteine: its possible relevance to cataract formation in diabetes","volume":"33","author":"Jain","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"10.1007\/s12603-010-0282-8_bib45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000266246","article-title":"Cataract and health status: a case-control study","volume":"201","author":"Chen","year":"1988","journal-title":"Ophthalmic Res"},{"key":"10.1007\/s12603-010-0282-8_bib46","doi-asserted-by":"crossref","first-page":"262","DOI":"10.3129\/can j ophthalmol.i07-013","article-title":"Population-based study of cataract surgery among patients with type 2 diabetes in Kinmen, Taiwan","volume":"42","author":"Tsai","year":"2007","journal-title":"Can J Ophthalmol"},{"key":"10.1007\/s12603-010-0282-8_bib47","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/0748233793009001-226","article-title":"Oxidation and aging: impact on vision","volume":"9","author":"Taylor","year":"1993","journal-title":"Toxicol Ind Health"},{"key":"10.1007\/s12603-010-0282-8_bib48","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1159\/000081206","article-title":"Vitamin E can protect against ultraviolet radiationinduced cataract in albino rats","volume":"36","author":"Ayala","year":"2004","journal-title":"Ophthalmic Res"},{"key":"10.1007\/s12603-010-0282-8_bib49","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1001\/jama.1993.03510220049033","article-title":"Vitamin status and intake as primary determinants of homocysteinemia in an elderly population","volume":"270","author":"Selhub","year":"1993","journal-title":"JAMA"},{"key":"10.1007\/s12603-010-0282-8_bib50","first-page":"39","article-title":"Folate, vitamin B12 and vitamin B6 and one carbon metabolism","volume":"6","author":"Selhub","year":"2002","journal-title":"J Nutr Health Aging"},{"key":"10.1007\/s12603-010-0282-8_bib51","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1111\/j.1600-0420.2004.00182.x","article-title":"Ocular changes, risk markers for eye disorders and effects of cataract surgery in elderly people: a study of an urban Swedish population followed from 70 to 97 years of age","volume":"82","author":"Bergman","year":"2004","journal-title":"Acta Ophthalmol Scand"}],"container-title":["The Journal of nutrition, health and aging"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12603-010-0282-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12603-010-0282-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1279770723023862?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1279770723023862?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12603-010-0282-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T13:05:50Z","timestamp":1761138350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1279770723023862"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,4]]},"references-count":51,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2011,4]]}},"alternative-id":["S1279770723023862"],"URL":"https:\/\/doi.org\/10.1007\/s12603-010-0282-8","relation":{},"ISSN":["1279-7707"],"issn-type":[{"value":"1279-7707","type":"print"}],"subject":[],"published":{"date-parts":[[2011,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between folate status, diabetes, antihypertensive medication and age-related cataracts in elderly Taiwanese","name":"articletitle","label":"Article Title"},{"value":"The Journal of nutrition, health and aging","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1007\/s12603-010-0282-8","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2011 SERDI Publisher.","name":"copyright","label":"Copyright"}]}}