{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T23:29:08Z","timestamp":1793834948625,"version":"4.6.1"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2016,5,9]],"date-time":"2016-05-09T00:00:00Z","timestamp":1462752000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/100007366","name":"Fondazione Italiana Sclerosi Multipla","doi-asserted-by":"publisher","award":["FISM \/2010\/R\/7"],"award-info":[{"award-number":["FISM \/2010\/R\/7"]}],"id":[{"id":"10.13039\/100007366","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Italian Ministry of Health (Bando Giovani Ricercatori 2010)","award":["GR-2010-2315964"],"award-info":[{"award-number":["GR-2010-2315964"]}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurotox Res"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1007\/s12640-016-9626-4","type":"journal-article","created":{"date-parts":[[2016,5,9]],"date-time":"2016-05-09T07:40:16Z","timestamp":1462779616000},"page":"338-344","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Altered NR4A Subfamily Gene Expression Level in Peripheral Blood of Parkinson\u2019s and Alzheimer\u2019s Disease Patients"],"prefix":"10.1007","volume":"30","author":[{"given":"Francesca","family":"Montarolo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Perga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serena","family":"Martire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9sir\u00e9e Nicole","family":"Navone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto","family":"Marchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Leotta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Bertolotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2016,5,9]]},"reference":[{"issue":"2","key":"9626_CR1","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.nbd.2009.12.029","volume":"38","author":"A Achiron","year":"2010","unstructured":"Achiron A, Grotto I, Balicer R, Magalashvili D, Feldman A, Gurevich M (2010) Microarray analysis identifies altered regulation of nuclear receptor family members in the pre-disease state of multiple sclerosis. Neurobiol Dis 38(2):201\u2013209","journal-title":"Neurobiol Dis"},{"issue":"1","key":"9626_CR2","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jns.2011.06.038","volume":"311","author":"A Achiron","year":"2011","unstructured":"Achiron A, Feldman A, Gurevich M (2011) Characterization of the multiple sclerosis traits: nuclear receptors (NR) impaired apoptosis pathway and the role of 1-alpha 25-dihydroxyvitamin D3. J Neurol Sci 311(1):9\u201314","journal-title":"J Neurol Sci"},{"key":"9626_CR3","doi-asserted-by":"crossref","first-page":"43277","DOI":"10.1074\/jbc.M107013200","volume":"276","author":"DS Castro","year":"2001","unstructured":"Castro DS, Hermanson E, Joseph B, Wallen A, Aarnisalo P, Heller A, Perlmann T (2001) Induction of cell cycle arrest and morphological differentiation by Nurr1 and retinoids in dopamine MN9D cells. J Biol Chem 276:43277\u201343284","journal-title":"J Biol Chem"},{"key":"9626_CR4","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/cne.10261","volume":"450","author":"Y Chu","year":"2002","unstructured":"Chu Y, Kompoliti K, Cochran EJ, Mufson EJ, Kordower JH (2002) Age-related decreases in Nurr1 immunoreactivity in the human substantia nigra. J Comp Neurol 450:203\u2013214","journal-title":"J Comp Neurol"},{"issue":"2","key":"9626_CR5","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1093\/toxsci\/kfu236","volume":"143","author":"BR Miranda De","year":"2014","unstructured":"De Miranda BR, Popichak KA, Hammond SL, Miller JA, Safe S, Tjalkens RB (2014) Novel para-phenyl substituted diindolylmethanes protect against MPTP neurotoxicity and suppress glial activation in a mouse model of Parkinson\u2019s disease. Toxicol Sci 143(2):360\u2013373","journal-title":"Toxicol Sci"},{"key":"9626_CR6","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1126\/science.290.5499.2140","volume":"290","author":"AM Urquiza de","year":"2000","unstructured":"de Urquiza AM, Liu S, Sjoberg M, Zetterstrom RH, Griffiths W, Sjovall J, Perlmann T (2000) Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290:2140\u20132144","journal-title":"Science"},{"key":"9626_CR7","first-page":"ra156","volume":"163","author":"M Decressac","year":"2012","unstructured":"Decressac M, Kadkhodaei B, Mattsson B, Laguna A, Perlmann T, Bjorklund A (2012) \u03b1-Synuclein-induced down-regulation of Nurr1 disrupts GDNF signaling in nigral dopamine neurons. Sci Transl Med 163:ra156","journal-title":"Sci Transl Med"},{"issue":"5","key":"9626_CR8","first-page":"689","volume":"20","author":"V Gigu\u00e8re","year":"1999","unstructured":"Gigu\u00e8re V (1999) Orphan nuclear receptors: from gene to function 1. Endocr Rev 20(5):689\u2013725","journal-title":"Endocr Rev"},{"issue":"1","key":"9626_CR9","doi-asserted-by":"crossref","first-page":"e8962","DOI":"10.1371\/journal.pone.0008962","volume":"5","author":"F Gilli","year":"2010","unstructured":"Gilli F, Lindberg RL, Valentino P, Marnetto F, Malucchi S, Sala A, Capobianco M, Di Sapio A, Sperli F, Kappos L, Calogero RA, Bertolotto A (2010) Learning from nature: pregnancy changes the expression of inflammation-related genes in patients with multiple sclerosis. PlosOne 5(1):e8962","journal-title":"PlosOne"},{"issue":"7","key":"9626_CR10","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1001\/archneurol.2011.32","volume":"68","author":"F Gilli","year":"2011","unstructured":"Gilli F, Navone ND, Perga S, Marnetto F, Caldano M, Capobianco M, Pulizzi A, Malucchi S, Bertolotto A (2011) Loss of braking signals during inflammation: a factor affecting the development and disease course of multiple sclerosis. Arch Neurol 68(7):879\u2013888","journal-title":"Arch Neurol"},{"key":"9626_CR11","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.neulet.2015.09.015","volume":"607","author":"SL Hammond","year":"2015","unstructured":"Hammond SL, Safe S, Tjalkensa RB (2015) A novel synthetic activator of Nurr1 induces dopaminergic gene expression and protects against 6-hydroxydopamine neurotoxicity in vitro. Neurosci Lett 607:83\u201389","journal-title":"Neurosci Lett"},{"issue":"10","key":"9626_CR12","doi-asserted-by":"crossref","first-page":"3593","DOI":"10.1172\/JCI64145","volume":"122","author":"JD Hawk","year":"2012","unstructured":"Hawk JD, Bookout AL, Poplawski SG, Bridi M, Rao AJ, Sulewski ME, Kroener BT, Manglesdorf DJ, Abel T (2012) NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors. J Clin Invest 122(10):3593\u20133602","journal-title":"J Clin Investig"},{"key":"9626_CR13","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1212\/01.WNL.0000118285.18383.90","volume":"62","author":"R Hering","year":"2004","unstructured":"Hering R, Petrovic S, Mietz EM, Holzmann C, Berg D, Bauer P, Woitalla D, M\u00fcller T, Berger K, Kr\u00fcger R, Riess O (2004) Extended mutation analysis and association studies of Nurr1 (NR4A2) in Parkinson disease. Neurology 62:1231\u20131232","journal-title":"Neurology"},{"issue":"50","key":"9626_CR14","doi-asserted-by":"crossref","first-page":"15923","DOI":"10.1523\/JNEUROSCI.3910-09.2009","volume":"29","author":"B Kadkhodaei","year":"2009","unstructured":"Kadkhodaei B, Ito T, Joodmardi E, Mattsson B, Rouillard C, Carta M, Muramatsu S, Sumi-Ichinose C, Nomura T, Metzger D, Chambon P, Lindqvist E, Larsson NG, Olson L, Bj\u00f6rklund A, Ichinose H, Perlmann T (2009) Nurr1 is required for maintenance of maturing and adult midbrain dopamine neurons. J Neurosci 29(50):15923\u201315932","journal-title":"J Neurosci"},{"key":"9626_CR15","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1073\/pnas.1221077110","volume":"110","author":"B Kadkhodaei","year":"2013","unstructured":"Kadkhodaei B, Alvarsson A, Alvarsson A, Schintu N, Ramskold D, Volakakis N, Joodmardi E, Yoshitake T, Kehr J, Decressac M, Bjorklund A, Sandberg R, Svenningsson P, Perlmann T (2013) Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons. Proc Natl Acad Sci USA 110:2360\u20132365","journal-title":"Proc Natl Acad Sci USA"},{"issue":"12","key":"9626_CR16","first-page":"2129","volume":"6","author":"SW Law","year":"1992","unstructured":"Law SW, Conneely OM, DeMayo FJ, O\u2019Malley BW (1992) Identification of a new brain-specific transcription factor, NURR1. Mol Endocrinol 6(12):2129\u20132135","journal-title":"Mol Endocrinol"},{"key":"9626_CR17","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1038\/ng1066","volume":"33","author":"W Le","year":"2003","unstructured":"Le W, Xu P, Jankovic J, Jiang H, Appel SH, Smith RG, Vassilatis DK (2003) Mutations in NR4A2 associated with familial Parkinson disease. Nat Genet 33:85\u201389","journal-title":"Nat Genet"},{"key":"9626_CR18","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.jns.2008.06.007","volume":"273","author":"W Le","year":"2008","unstructured":"Le W, Pan T, Huang M, Xu P, Xie W, Zhu W, Zhang X, Deng H, Jankovic J (2008) Decreased NURR1 gene expression in patients with Parkinson\u2019s disease. J Neurol Sci 273:29\u201333","journal-title":"J Neurol Sci"},{"key":"9626_CR19","first-page":"533","volume":"21","author":"QX Li","year":"2006","unstructured":"Li QX, Ke N, Sundaram R, Wong-Staal F (2006) NR4A1, 2, 3-an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis. Histol Histopathol 21:533\u2013540","journal-title":"Histol Histopathol"},{"key":"9626_CR20","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1111\/j.1468-1331.2011.03644.x","volume":"19","author":"H Liu","year":"2012","unstructured":"Liu H, Wei L, Tao Q, Deng H, Ming M, Xu P, Le W (2012) Decreased NURR1 and PITX3 gene expression in Chinese patients with Parkinson\u2019s disease. Eur J Neurol 19:870\u2013875","journal-title":"Eur J Neurol"},{"issue":"3","key":"9626_CR21","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1111\/j.1468-1331.2012.03824.x","volume":"20","author":"H Liu","year":"2013","unstructured":"Liu H, Tao Q, Deng H, Ming M, Ding Y, Xu P, Chen S, Song Z, Le W (2013) Genetic analysis of NR4A2 gene in a large population of Han Chinese patients with Parkinson\u2019s disease. Eur J Neurol 20(3):584\u2013587","journal-title":"Eur J Neurol"},{"key":"9626_CR22","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1101\/gad.16872411","volume":"25","author":"M Malewicz","year":"2011","unstructured":"Malewicz M, Kadkhodaei B, Kee N, Volakakis N, Hellman U, Viktorsson K, Leung CY, Chen B, Lewensohn R, van Gent DC, Chen DJ, Perlmann T (2011) Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair. Genes Dev 25:2031\u20132040","journal-title":"Genes Dev"},{"key":"9626_CR23","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1042\/BST0390688","volume":"39","author":"JP McMorrow","year":"2011","unstructured":"McMorrow JP, Murphy EP (2011) Inflammation: a role for NR4A orphan nuclear receptors? Biochem Soc Trans 39:688\u2013693","journal-title":"Biochem Soc Trans"},{"issue":"12","key":"9626_CR24","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1101\/lm.026385.112","volume":"19","author":"SE McNulty","year":"2012","unstructured":"McNulty SE, Barrett RM, Vogel-Ciernia A, Malvaez M, Hernandez N, Davatolhagh MF, Matheos DP, Schiffman A, Wood MA (2012) Differential roles for Nr4a1 and Nr4a2 in object location versus object recognition long-term memory. Learn Mem 19(12):588\u2013592","journal-title":"Learn Mem"},{"issue":"5","key":"9626_CR25","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/nrd3430","volume":"10","author":"WG Meissner","year":"2011","unstructured":"Meissner WG (2011) Priorities in Parkinson\u2019s disease research. Nat Rev Drug Discov 10(5):377\u2013393","journal-title":"Nat Rev Drug Discov"},{"issue":"3","key":"9626_CR26","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0896-6273(88)90138-9","volume":"1","author":"J Milbrandt","year":"1988","unstructured":"Milbrandt J (1988) Nerve growth factor induces a gene homologous to the glucocorticoid receptor gene. Neuron 1(3):183\u2013188","journal-title":"Neuron"},{"key":"9626_CR27","doi-asserted-by":"crossref","first-page":"3223","DOI":"10.1158\/1078-0432.CCR-11-2953","volume":"18","author":"H Mohan","year":"2012","unstructured":"Mohan H, Aherne CM, Rogers AC, Baird AW, Winter DC, Murphy EP (2012) Molecular pathways: the role of NR4A orphan nuclear receptors in cancer. Clin Cancer Res 18:3223\u20133228","journal-title":"Clin Cancer Res"},{"key":"9626_CR28","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/nm1579","volume":"13","author":"SE Mullican","year":"2007","unstructured":"Mullican SE, Zhang S, Konopleva M (2007) Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia. Nat Med 13:730\u2013735","journal-title":"Nat Med"},{"issue":"1\u20132","key":"9626_CR29","first-page":"99102","volume":"272","author":"ND Navone","year":"2014","unstructured":"Navone ND, Perga S, Martire S, Berchialla P, Malucchi S, Bertolotto A (2014) Monocytes and CD4+\u00a0T cells contribution to the under-expression of NR4A2 and TNFAIP3 genes in patients with Multiple Sclerosis. J Neuroimmunol 272(1\u20132):99102","journal-title":"J Neuroimmunol"},{"key":"9626_CR30","doi-asserted-by":"crossref","first-page":"510","DOI":"10.15252\/emmm.201404610","volume":"7","author":"S Oh","year":"2015","unstructured":"Oh S, Chang M, Song J, Rhee Y, Joe E, Lee H, Yi Lee S (2015) Combined Nurr1 and Foxa2 roles in the therapy of Parkinson\u2019s disease. EMBO Mol Med 7:510\u2013525","journal-title":"EMBO Mol Med"},{"issue":"3","key":"9626_CR31","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1006\/bbrc.1994.2900","volume":"205","author":"N Ohkura","year":"1994","unstructured":"Ohkura N, Hijikuro M, Yamamoto A, Miki K (1994) Molecular cloning of a novel thyroid\/steroid receptor superfamily gene from cultured rat neuronal cells. Biochem Biophys Res Commun 205(3):1959\u20131965","journal-title":"Biochem Biophys Res Commun"},{"key":"9626_CR32","doi-asserted-by":"crossref","first-page":"4264","DOI":"10.1038\/srep04264","volume":"4","author":"S P\u00e8rez-Sieira","year":"2014","unstructured":"P\u00e8rez-Sieira S, L\u00f2pez M, Nogueiras R, Tovar S (2014) Regulation of NR4A by nutritional status, gender, postnatal development and hormonal deficiency. Sci Rep 4:4264","journal-title":"Sci Rep"},{"key":"9626_CR33","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1101\/gad.9.7.769","volume":"9","author":"T Perlmann","year":"1995","unstructured":"Perlmann T, Jansson L (1995) A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 9:769\u2013782","journal-title":"Genes Dev"},{"issue":"5","key":"9626_CR34","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1189\/jlb.0507296","volume":"82","author":"AD Reynolds","year":"2007","unstructured":"Reynolds AD, Banerjee R, Liu J, Gendelman HE, Mosley RL (2007) Neuroprotective activities of CD4+\u00a0CD25+\u00a0regulatory T cells in an animal model of Parkinson\u2019s disease. J Leukoc Biol 82(5):1083\u20131094","journal-title":"J Leukoc Biol"},{"key":"9626_CR35","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jsbmb.2015.04.016","volume":"157","author":"S Safe","year":"2015","unstructured":"Safe S, Jin U, Morpurgo B, Abudayyeh A, Singh M, Tjalkens RB (2015) Nuclear receptor 4A (NR4A) family\u2014orphans no more. J Steroid Biochem Mol Biol 157:48\u201360","journal-title":"J Steroid Biochem Mol Biol"},{"key":"9626_CR36","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.cell.2009.01.038","volume":"137","author":"K Saijo","year":"2009","unstructured":"Saijo K, Winner B, Carson CT, Collier JG, Boyer L, Rosenfeld MG, Gage FH, Glass CK (2009) A Nurr1\/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137:47\u201359","journal-title":"Cell"},{"key":"9626_CR37","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1038\/ncomms1272","volume":"2","author":"T Sekiya","year":"2011","unstructured":"Sekiya T, Kashiwagi I, Inoue N, Morita R, Hori S, Waldmann H, Rudensky AY, Ichinose H, Metzger D, Chambon P, Yoshimura A (2011) The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nat Comm 2:269","journal-title":"Nat Comm"},{"issue":"3","key":"9626_CR38","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1038\/ni.2520","volume":"14","author":"T Sekiya","year":"2013","unstructured":"Sekiya T, Kashiwagi I, Yoshida R, Fukaya T, Morita R, Kimura A, Ichinose H, Metzger D, Chambon P, Yoshimura A (2013) Nr4a receptors are essential for thymic regulatory T cell development and immune homeostasis. Nat Immunol 14(3):230\u2013237","journal-title":"Nat Immunol"},{"key":"9626_CR39","doi-asserted-by":"crossref","first-page":"12317","DOI":"10.1073\/pnas.1007088107","volume":"107","author":"N Volakakis","year":"2010","unstructured":"Volakakis N, Kadkhodaei B, Joodmardi E, Wallis K, Panman L, Silvaggi J, Spiegelman BM, Perlmann T (2010) NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection. Proc Natl Acad Sci USA 107:12317\u201312322","journal-title":"Proc Natl Acad Sci USA"},{"issue":"6939","key":"9626_CR40","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/nature01645","volume":"423","author":"Z Wang","year":"2003","unstructured":"Wang Z, Benoit G, Liu J, Prasad S, Aarnisalo P, Liu X, Xu H, Walker NP, Perlmann T (2003) Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors. Nature 423(6939):555\u2013560","journal-title":"Nature"},{"key":"9626_CR41","doi-asserted-by":"crossref","first-page":"38","DOI":"10.2174\/1389450115666141120112818","volume":"16","author":"K Wenzl","year":"2015","unstructured":"Wenzl K, Troppan K, Neumeister P, Deutsch AJA (2015) The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms. Curr Drug Targ. 16:38\u201346","journal-title":"Curr Drug Targ."},{"key":"9626_CR42","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1126\/science.276.5310.248","volume":"276","author":"RH Zetterstrom","year":"1997","unstructured":"Zetterstrom RH, Solomin L, Jansson L, Hoffer BJ, Olson L, Perlman T (1997) Dopamine neuron agenesis in Nurr1-deficient mice. Science 276:248\u2013250","journal-title":"Science"},{"key":"9626_CR43","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1001\/archneur.60.5.722","volume":"60","author":"K Zheng","year":"2003","unstructured":"Zheng K, Heydari B, Simon DK (2003) A common NURR1 polymorphism associated with Parkinson disease and diffuse Lewy body disease. Arch Neurol 60:722\u2013725","journal-title":"Arch Neurol"}],"updated-by":[{"DOI":"10.1007\/s12640-016-9685-6","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2016,12,2]],"date-time":"2016-12-02T00:00:00Z","timestamp":1480636800000}}],"container-title":["Neurotoxicity Research"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12640-016-9626-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12640-016-9626-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12640-016-9626-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12640-016-9626-4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T09:31:32Z","timestamp":1559467892000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12640-016-9626-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,9]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["9626"],"URL":"https:\/\/doi.org\/10.1007\/s12640-016-9626-4","relation":{"correction":[{"id-type":"doi","id":"10.1007\/s12640-016-9685-6","asserted-by":"object"}]},"ISSN":["1029-8428","1476-3524"],"issn-type":[{"value":"1029-8428","type":"print"},{"value":"1476-3524","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,9]]}}}