{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,29]],"date-time":"2026-01-29T12:30:42Z","timestamp":1769689842587,"version":"3.49.0"},"reference-count":49,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T00:00:00Z","timestamp":1598486400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T00:00:00Z","timestamp":1598486400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"funder":[{"DOI":"10.13039\/501100005851","name":"Shahid Beheshti University of Medical Sciences","doi-asserted-by":"publisher","award":["91-6124"],"award-info":[{"award-number":["91-6124"]}],"id":[{"id":"10.13039\/501100005851","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Neurotox Res"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1007\/s12640-020-00276-z","type":"journal-article","created":{"date-parts":[[2020,8,27]],"date-time":"2020-08-27T07:03:54Z","timestamp":1598511834000},"page":"413-428","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Tissue Plasminogen Activator Loaded PCL Nanofibrous Scaffold Promoted Nerve Regeneration After Sciatic Nerve Transection in Male Rats"],"prefix":"10.1007","volume":"39","author":[{"given":"Ensieh","family":"Sajadi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abbas","family":"Aliaghaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza Mastery","family":"Farahni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Rashidiani-Rashidabadi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir","family":"Raoofi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousef","family":"Sadeghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Bagheri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saba","family":"Ilkhani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6947-3285","authenticated-orcid":false,"given":"Mohammad-Amin","family":"Abdollahifar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2020,8,27]]},"reference":[{"issue":"5","key":"276_CR1","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1083\/jcb.149.5.1157","volume":"149","author":"K Akassoglou","year":"2000","unstructured":"Akassoglou K, Kombrinck KW, Degen JL, Strickland S (2000) Tissue plasminogen activator\u2013mediated fibrinolysis protects against axonal degeneration and demyelination after sciatic nerve injury. J Cell Biol 149(5):1157\u20131166","journal-title":"J Cell Biol"},{"issue":"9","key":"276_CR2","doi-asserted-by":"crossref","first-page":"2238","DOI":"10.1021\/bm100221h","volume":"11","author":"MA Alvarez-Perez","year":"2010","unstructured":"Alvarez-Perez MA, Guarino V, Cirillo V, Ambrosio L (2010) Influence of gelatin cues in PCL electrospun membranes on nerve outgrowth. Biomacromolecules 11(9):2238\u20132246","journal-title":"Biomacromolecules"},{"issue":"1","key":"276_CR3","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1750-0680-4-7","volume":"4","author":"H B\u00f6ttcher","year":"2009","unstructured":"B\u00f6ttcher H, Eisbrenner K, Fritz S, Kindermann G, Kraxner F, McCallum I, Obersteiner M (2009) An assessment of monitoring requirements and costs of \u2018Reduced Emissions from Deforestation and Degradation\u2019. Carbon Balance and Management 4(1):7","journal-title":"Carbon Balance and Management"},{"issue":"12","key":"276_CR4","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1016\/j.addr.2009.07.009","volume":"61","author":"H Cao","year":"2009","unstructured":"Cao H, Liu T, Chew SY (2009) The application of nanofibrous scaffolds in neural tissue engineering. Adv Drug Deliv Rev 61(12):1055\u20131064","journal-title":"Adv Drug Deliv Rev"},{"issue":"6","key":"276_CR5","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.biomaterials.2007.10.025","volume":"29","author":"SY Chew","year":"2008","unstructured":"Chew SY, Mi R, Hoke A, Leong KW (2008) The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. Biomaterials 29(6):653\u2013661","journal-title":"Biomaterials"},{"issue":"3","key":"276_CR6","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.actbio.2007.01.002","volume":"3","author":"EJ Chong","year":"2007","unstructured":"Chong EJ, Phan TT, Lim IJ, Zhang Y, Bay BH, Ramakrishna S, Lim CT (2007) Evaluation of electrospun PCL\/gelatin nanofibrous scaffold for wound healing and layered dermal reconstitution. Acta Biomater 3(3):321\u2013330","journal-title":"Acta Biomater"},{"issue":"19\u201320","key":"276_CR7","doi-asserted-by":"crossref","first-page":"2030","DOI":"10.1089\/ten.tea.2011.0496","volume":"18","author":"F Frattini","year":"2012","unstructured":"Frattini F, Pereira Lopes FR, Almeida FM, Rodrigues RF, Boldrini LC, Tomaz MA, Baptista AF, Melo PA, Martinez AMB (2012) Mesenchymal stem cells in a polycaprolactone conduit promote sciatic nerve regeneration and sensory neuron survival after nerve injury. Tissue Eng A 18(19\u201320):2030\u20132039","journal-title":"Tissue Eng A"},{"issue":"19","key":"276_CR8","doi-asserted-by":"crossref","first-page":"3793","DOI":"10.1038\/sj.emboj.7600397","volume":"23","author":"L Fredriksson","year":"2004","unstructured":"Fredriksson L, Li H, Fieber C, Li X, Eriksson U (2004) Tissue plasminogen activator is a potent activator of PDGF-CC. EMBO J 23(19):3793\u20133802","journal-title":"EMBO J"},{"issue":"2","key":"276_CR9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/0304-3940(94)90502-9","volume":"180","author":"M Garc\u00eda-Rocha","year":"1994","unstructured":"Garc\u00eda-Rocha M, Avila J, Armas-Portela R (1994) Tissue-type plasminogen activator (tPA) is the main plasminogen activator associated with isolated rat nerve growth cones. Neurosci Lett 180(2):123\u2013126","journal-title":"Neurosci Lett"},{"issue":"34","key":"276_CR10","doi-asserted-by":"crossref","first-page":"4532","DOI":"10.1016\/j.biomaterials.2008.08.007","volume":"29","author":"L Ghasemi-Mobarakeh","year":"2008","unstructured":"Ghasemi-Mobarakeh L, Prabhakaran MP, Morshed M, Nasr-Esfahani M-H, Ramakrishna S (2008) Electrospun poly (\u025b-caprolactone)\/gelatin nanofibrous scaffolds for nerve tissue engineering. Biomaterials 29(34):4532\u20134539","journal-title":"Biomaterials"},{"key":"276_CR11","doi-asserted-by":"crossref","unstructured":"Grinsell, D. and C. Keating (2014). Peripheral nerve reconstruction after injury: a review of clinical and experimental therapies. BioMed research international 2014","DOI":"10.1155\/2014\/698256"},{"issue":"7\u201312","key":"276_CR12","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1111\/j.1699-0463.1988.tb00954.x","volume":"96","author":"H Gundersen","year":"1988","unstructured":"Gundersen H, Bagger P, Bendtsen T, Evans S, Korbo L, Marcussen N, M\u00f8ller A, Nielsen K, Nyengaard J, Pakkenberg B (1988a) The new stereological tools: disector, fractionator, nucleator and point sampled intercepts and their use in pathological research and diagnosis. Apmis 96(7\u201312):857\u2013881","journal-title":"Apmis"},{"issue":"1\u20136","key":"276_CR13","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1111\/j.1699-0463.1988.tb05320.x","volume":"96","author":"H Gundersen","year":"1988","unstructured":"Gundersen H, Bendtsen TF, Korbo L, Marcussen N, M\u00f8ller A, Nielsen K, Nyengaard J, Pakkenberg B, S\u00f8rensen FB, Vesterby A (1988b) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. Apmis 96(1\u20136):379\u2013394","journal-title":"Apmis"},{"issue":"2","key":"276_CR14","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1002\/cne.902840206","volume":"284","author":"B Himes","year":"1989","unstructured":"Himes B, Tessler A (1989) Death of some dorsal root ganglion neurons and plasticity of others following sciatic nerve section in adult and neonatal rats. J Comp Neurol 284(2):215\u2013230","journal-title":"J Comp Neurol"},{"issue":"1","key":"276_CR15","doi-asserted-by":"crossref","first-page":"650857","DOI":"10.4061\/2010\/650857","volume":"1","author":"JK Hyun","year":"2010","unstructured":"Hyun JK, Kim H-W (2010) Clinical and experimental advances in regeneration of spinal cord injury. Journal of tissue engineering 1(1):650857","journal-title":"Journal of tissue engineering"},{"issue":"1","key":"276_CR16","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1365-2818.1979.tb00149.x","volume":"115","author":"EB Jensen","year":"1979","unstructured":"Jensen EB, Gundersen HJG, \u00d8sterby R (1979) Determination of membrane thickness distribution from orthogonal intercepts. J Microsc 115(1):19\u201333","journal-title":"J Microsc"},{"issue":"3","key":"276_CR17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.injury.2008.06.015","volume":"39","author":"EO Johnson","year":"2008","unstructured":"Johnson EO, Charchanti A, Soucacos PN (2008) Nerve repair: experimental and clinical evaluation of neurotrophic factors in peripheral nerve regeneration. Injury 39(3):37\u201342","journal-title":"Injury"},{"issue":"2","key":"276_CR18","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1046\/j.1365-2818.1997.1460700.x","volume":"186","author":"LM Karlsson","year":"1997","unstructured":"Karlsson LM, Cruz-Orive L (1997) Estimation of mean particle size from single sections. J Microsc 186(2):121\u2013132","journal-title":"J Microsc"},{"issue":"2","key":"276_CR19","first-page":"283","volume":"78","author":"CH Kim","year":"2006","unstructured":"Kim CH, Khil MS, Kim HY, Lee HU, Jahng KY (2006) An improved hydrophilicity via electrospinning for enhanced cell attachment and proliferation. Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials 78(2):283\u2013290","journal-title":"Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials"},{"issue":"26","key":"276_CR20","doi-asserted-by":"crossref","first-page":"3574","DOI":"10.1016\/j.biomaterials.2008.05.014","volume":"29","author":"H Koh","year":"2008","unstructured":"Koh H, Yong T, Chan C, Ramakrishna S (2008) Enhancement of neurite outgrowth using nano-structured scaffolds coupled with laminin. Biomaterials 29(26):3574\u20133582","journal-title":"Biomaterials"},{"issue":"1","key":"276_CR21","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/S0165-0270(98)00129-0","volume":"85","author":"JO Larsen","year":"1998","unstructured":"Larsen JO (1998) Stereology of nerve cross sections. J Neurosci Methods 85(1):107\u2013118","journal-title":"J Neurosci Methods"},{"issue":"11","key":"276_CR22","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1016\/j.biomaterials.2004.04.037","volume":"26","author":"CH Lee","year":"2005","unstructured":"Lee CH, Shin HJ, Cho IH, Kang Y-M, Kim IA, Park K-D, Shin J-W (2005) Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. Biomaterials 26(11):1261\u20131270","journal-title":"Biomaterials"},{"issue":"4","key":"276_CR23","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.actbio.2006.02.005","volume":"2","author":"W-J Li","year":"2006","unstructured":"Li W-J, Cooper JA Jr, Mauck RL, Tuan RS (2006) Fabrication and characterization of six electrospun poly (\u03b1-hydroxy ester)-based fibrous scaffolds for tissue engineering applications. Acta Biomater 2(4):377\u2013385","journal-title":"Acta Biomater"},{"issue":"11","key":"276_CR24","doi-asserted-by":"crossref","first-page":"7717","DOI":"10.1073\/pnas.102088899","volume":"99","author":"N Mataga","year":"2002","unstructured":"Mataga N, Nagai N, Hensch TK (2002) Permissive proteolytic activity for visual cortical plasticity. Proc Natl Acad Sci 99(11):7717\u20137721","journal-title":"Proc Natl Acad Sci"},{"issue":"3","key":"276_CR25","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/0009-9120(90)90601-P","volume":"23","author":"M Mayer","year":"1990","unstructured":"Mayer M (1990) Biochemical and biological aspects of the plasminogen activation system. Clin Biochem 23(3):197\u2013211","journal-title":"Clin Biochem"},{"issue":"9","key":"276_CR26","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.prp.2011.06.011","volume":"207","author":"A Noorafshan","year":"2011","unstructured":"Noorafshan A, Omidi A, Karbalay-Doust S (2011) Curcumin protects the dorsal root ganglion and sciatic nerve after crush in rat. Pathology-Research and Practice 207(9):577\u2013582","journal-title":"Pathology-Research and Practice"},{"issue":"4","key":"276_CR27","first-page":"427","volume":"13","author":"A Noorafshan","year":"2012","unstructured":"Noorafshan A, Hoseini L, Karbalay-Doust S, Nadimi E (2012) A simple stereological method for estimating the number and the volume of the pancreatic beta cells. JOP Journal of the Pancreas 13(4):427\u2013432","journal-title":"JOP Journal of the Pancreas"},{"issue":"2","key":"276_CR28","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.neulet.2005.11.024","volume":"396","author":"A Pierucci","year":"2006","unstructured":"Pierucci A, de Oliveira ALR (2006) Increased sensory neuron apoptotic death 2 weeks after peripheral axotomy in C57BL\/6J mice compared to A\/J mice. Neurosci Lett 396(2):127\u2013131","journal-title":"Neurosci Lett"},{"issue":"2","key":"276_CR29","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1046\/j.1471-4159.1995.64020566.x","volume":"64","author":"RN Pittman","year":"1995","unstructured":"Pittman RN, DiBenedetto AJ (1995) PC12 cells overexpressing tissue plasminogen activator regenerate neurites to a greater extent and migrate faster than control cells in complex extracellular matrix. J Neurochem 64(2):566\u2013575","journal-title":"J Neurochem"},{"issue":"45","key":"276_CR30","doi-asserted-by":"crossref","first-page":"455102","DOI":"10.1088\/0957-4484\/19\/45\/455102","volume":"19","author":"MP Prabhakaran","year":"2008","unstructured":"Prabhakaran MP, Venugopal J, Chan CK, Ramakrishna S (2008) Surface modified electrospun nanofibrous scaffolds for nerve tissue engineering. Nanotechnology 19(45):455102","journal-title":"Nanotechnology"},{"issue":"6411","key":"276_CR31","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/361453a0","volume":"361","author":"Z Qian","year":"1993","unstructured":"Qian Z, Gilbert ME, Colicos MA, Kandel ER, Kuhl D (1993) Tissue-plasminogen activator is induced as an immediate\u2013early gene during seizure, kindling and long-term potentiation. Nature 361(6411):453\u2013457","journal-title":"Nature"},{"issue":"22","key":"276_CR32","doi-asserted-by":"crossref","first-page":"4007","DOI":"10.1242\/jcs.112.22.4007","volume":"112","author":"AD Rogove","year":"1999","unstructured":"Rogove AD, Siao C, Keyt B, Strickland S, Tsirka SE (1999) Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system. J Cell Sci 112(22):4007\u20134016","journal-title":"J Cell Sci"},{"issue":"19","key":"276_CR33","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1016\/j.biomaterials.2007.03.009","volume":"28","author":"E Schnell","year":"2007","unstructured":"Schnell E, Klinkhammer K, Balzer S, Brook G, Klee D, Dalton P, Mey J (2007) Guidance of glial cell migration and axonal growth on electrospun nanofibers of poly-\u03b5-caprolactone and a collagen\/poly-\u03b5-caprolactone blend. Biomaterials 28(19):3012\u20133025","journal-title":"Biomaterials"},{"issue":"5244","key":"276_CR34","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1126\/science.270.5244.1992","volume":"270","author":"NW Seeds","year":"1995","unstructured":"Seeds NW, Williams BL, Bickford PC (1995) Tissue plasminogen activator induction in Purkinje neurons after cerebellar motor learning. Science 270(5244):1992\u20131994","journal-title":"Science"},{"issue":"12","key":"276_CR35","doi-asserted-by":"crossref","first-page":"4348","DOI":"10.1523\/JNEUROSCI.21-12-04348.2001","volume":"21","author":"LB Siconolfi","year":"2001","unstructured":"Siconolfi LB, Seeds NW (2001) Mice lacking tPA, uPA, or plasminogen genes showed delayed functional recovery after sciatic nerve crush. J Neurosci 21(12):4348\u20134355","journal-title":"J Neurosci"},{"key":"276_CR36","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0074-7742(09)87008-6","volume":"87","author":"M Siemionow","year":"2009","unstructured":"Siemionow M, Brzezicki G (2009) Current techniques and concepts in peripheral nerve repair. Int Rev Neurobiol 87:141\u2013172","journal-title":"Int Rev Neurobiol"},{"issue":"1","key":"276_CR37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1042\/BA20060217","volume":"48","author":"M Soleimani","year":"2007","unstructured":"Soleimani M, Mahboudi F, Davoudi N, Amanzadeh A, Azizi M, Adeli A, Rastegar H, Barkhordari F, Mohajer-Maghari B (2007) Expression of human tissue plasminogen activator in the trypanosomatid protozoan Leishmania tarentolae. Biotechnol Appl Biochem 48(1):55\u201361","journal-title":"Biotechnol Appl Biochem"},{"issue":"1","key":"276_CR38","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1469-7580.1999.19410001.x","volume":"194","author":"G Terenghi","year":"1999","unstructured":"Terenghi G (1999) Peripheral nerve regeneration and neurotrophic factors. The Journal of Anatomy 194(1):1\u201314","journal-title":"The Journal of Anatomy"},{"issue":"6547","key":"276_CR39","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1038\/377340a0","volume":"377","author":"SE Tsirka","year":"1995","unstructured":"Tsirka SE, Gualandris A, Amaral DG, Strickland S (1995) Excitotoxin-induced neuronal degeneration and seizure are mediated by tissue plasminogen activator. Nature 377(6547):340\u2013344","journal-title":"Nature"},{"issue":"2","key":"276_CR40","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1523\/JNEUROSCI.17-02-00543.1997","volume":"17","author":"SE Tsirka","year":"1997","unstructured":"Tsirka SE, Rogove AD, Bugge TH, Degen JL, Strickland S (1997) An extracellular proteolytic cascade promotes neuronal degeneration in the mouse hippocampus. J Neurosci 17(2):543\u2013552","journal-title":"J Neurosci"},{"issue":"2","key":"276_CR41","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1179\/016164104225013833","volume":"26","author":"AS Varej\u00e3o","year":"2004","unstructured":"Varej\u00e3o AS, Melo-Pinto P, Meek MF, Filipe VM, Bulas-Cruz J (2004) Methods for the experimental functional assessment of rat sciatic nerve regeneration. Neurol Res 26(2):186\u2013194","journal-title":"Neurol Res"},{"issue":"4","key":"276_CR42","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1172\/JCI115405","volume":"88","author":"J-D Vassalli","year":"1991","unstructured":"Vassalli J-D, Sappino A, Belin D (1991) The plasminogen activator\/plasmin system. J Clin Invest 88(4):1067\u20131072","journal-title":"J Clin Invest"},{"issue":"2","key":"276_CR43","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/(SICI)1096-9861(19971117)388:2<307::AID-CNE8>3.0.CO;2-5","volume":"388","author":"S Vestergaard","year":"1997","unstructured":"Vestergaard S, Tandrup T, Jakobsen J (1997) Effect of permanent axotomy on number and volume of dorsal root ganglion cell bodies. J Comp Neurol 388(2):307\u2013312","journal-title":"J Comp Neurol"},{"issue":"4\u20135","key":"276_CR44","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.addr.2007.03.014","volume":"59","author":"SM Willerth","year":"2007","unstructured":"Willerth SM, Sakiyama-Elbert SE (2007) Approaches to neural tissue engineering using scaffolds for drug delivery. Adv Drug Deliv Rev 59(4\u20135):325\u2013338","journal-title":"Adv Drug Deliv Rev"},{"issue":"6","key":"276_CR45","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1083\/jcb.148.6.1295","volume":"148","author":"YP Wu","year":"2000","unstructured":"Wu YP, Siao C-J, Lu W, Sung T-C, Frohman MA, Milev P, Bugge TH, Degen JL, Levine JM, Margolis RU (2000) The tissue plasminogen activator (tPA\/plasmin) extracellular proteolytic system regulates seizure-induced hippocampal mossy fiber outgrowth through a proteoglycan substrate. J Cell Biol 148(6):1295\u20131304","journal-title":"J Cell Biol"},{"issue":"8","key":"276_CR46","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1016\/j.biomaterials.2007.10.058","volume":"29","author":"L Yang","year":"2008","unstructured":"Yang L, Fitie CF, van der Werf KO, Bennink ML, Dijkstra PJ, Feijen J (2008) Mechanical properties of single electrospun collagen type I fibers. Biomaterials 29(8):955\u2013962","journal-title":"Biomaterials"},{"issue":"12","key":"276_CR47","doi-asserted-by":"crossref","first-page":"1571","DOI":"10.1172\/JCI0214308","volume":"109","author":"M Yepes","year":"2002","unstructured":"Yepes M, Sandkvist M, Coleman TA, Moore E, Wu J-Y, Mitola D, Bugge TH, Lawrence DA (2002) Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent. J Clin Invest 109(12):1571\u20131578","journal-title":"J Clin Invest"},{"issue":"1","key":"276_CR48","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/1471-2202-12-68","volume":"12","author":"W Yu","year":"2011","unstructured":"Yu W, Zhao W, Zhu C, Zhang X, Ye D, Zhang W, Zhou Y, Jiang X, Zhang Z (2011) Sciatic nerve regeneration in rats by a promising electrospun collagen\/poly (\u03b5-caprolactone) nerve conduit with tailored degradation rate. BMC Neurosci 12(1):68","journal-title":"BMC Neurosci"},{"issue":"1","key":"276_CR49","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/00007890-198101000-00020","volume":"31","author":"AA Zalewski","year":"1981","unstructured":"Zalewski AA, Gulati AK (1981) Rejection of nerve allografts after cessation of immunosuppression with cyclosporin A. Transplantation 31(1):88\u201389","journal-title":"Transplantation"}],"container-title":["Neurotoxicity Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12640-020-00276-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12640-020-00276-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12640-020-00276-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T00:24:18Z","timestamp":1630023858000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12640-020-00276-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8,27]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["276"],"URL":"https:\/\/doi.org\/10.1007\/s12640-020-00276-z","relation":{},"ISSN":["1029-8428","1476-3524"],"issn-type":[{"value":"1029-8428","type":"print"},{"value":"1476-3524","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8,27]]},"assertion":[{"value":"28 May 2020","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"19 August 2020","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"20 August 2020","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"27 August 2020","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Compliance with Ethical Standards"}},{"value":"The authors declare that they have no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}},{"value":"All procedures were approved by the Medical Ethics Committee at Shahid Beheshti University of Medical Sciences, Tehran, Iran (IR.SBMU.MSP.REC. 1396.544).","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval"}}]}}