{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T15:25:58Z","timestamp":1791818758599,"version":"4.3.4"},"reference-count":43,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T00:00:00Z","timestamp":1733788800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"name":"A.T. Still University, Mesa"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["J. Maxillofac. Oral Surg."],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Objective<\/jats:title>\n            <jats:p>This study analyzed clinical parameters to assess whether dental implant material is a risk factor for peri-implantitis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods<\/jats:title>\n            <jats:p>A literature search was performed on PubMed Central, Cochrane, PubMed\/MEDLINE, Embase, and Scopus. The PICO strategy involved healthy patient, partially or fully edentulous, receiving at least one dental implant; zirconia or titanium dental implants; comparison involving assessment of whether there were differences in the risk of peri-implantitis among different materials used for dental implants; clinical parameters. Quality assessment was performed using the modified Jadad scale.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results<\/jats:title>\n            <jats:p>Nineteen articles met the inclusion criteria. BoP did not have statistically significant differences comparing zirconia and titanium implants or natural teeth. MBL had diversified results; sometimes, it was higher in zirconia implants than titanium; otherwise, there was no significant difference. Comparing implants with natural teeth, MBL was lower in titanium implants over prolonged observation periods, and greater severity was found in the zirconia group. Notably, natural teeth had minimal bone loss. Zirconia implants demonstrated reduced plaque accumulation and minimal microbial contamination compared to titanium implants and control teeth. The quality assessment was considered poor to low in 9 studies and good to excellent in 10. The development of peri-implantitis was influenced by several patient-specific and clinical factors, underscoring the need to adopt a comprehensive and personalized approach to implant dentistry and peri-implantitis prevention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion<\/jats:title>\n            <jats:p>It was not possible to draft any solid conclusion for the relationship between implant material and peri-implantitis.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1007\/s12663-024-02409-9","type":"journal-article","created":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T14:41:41Z","timestamp":1733841701000},"page":"1010-1028","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Clinical Assessment of the Relationship of Dental Implant Materials (Titanium and Zirconia) and Peri-Implantitis: A Systematic Review"],"prefix":"10.1007","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1073-9920","authenticated-orcid":false,"given":"Deepti","family":"Shrivastava","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Altafuddin","family":"Quadri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulkhaliq Ali F.","family":"Alshadidi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravinder","family":"Saini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4678-0260","authenticated-orcid":false,"given":"Meghna","family":"Dewan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3022-4390","authenticated-orcid":false,"given":"Gustavo Vicentis Oliveira","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5969-6810","authenticated-orcid":false,"given":"Kumar Chandan","family":"Srivastava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2024,12,10]]},"reference":[{"issue":"Suppl 1","key":"2409_CR1","doi-asserted-by":"publisher","first-page":"S117","DOI":"10.4103\/0975-7406.113310","volume":"5","author":"K Karthik","year":"2013","unstructured":"Karthik K, Thangaswamy V (2013) Evaluation of implant success: a review of past and present concepts. J Pharm Bioallied Sci 5(Suppl 1):S117\u2013S119","journal-title":"J Pharm Bioallied Sci"},{"key":"2409_CR2","doi-asserted-by":"publisher","first-page":"24","DOI":"10.4012\/dmj.2019-172","volume":"39","author":"T Hanawa","year":"2020","unstructured":"Hanawa T (2020) Zirconia versus titanium in dentistry: a review. Dent Mater J 39:24\u201336","journal-title":"Dent Mater J"},{"key":"2409_CR3","doi-asserted-by":"publisher","first-page":"6279","DOI":"10.1007\/s00784-023-05242-5","volume":"27","author":"NM Padhye","year":"2023","unstructured":"Padhye NM, Calciolari E, Zuercher AN, Tagliaferri S, Donos N (2023) Survival and success of zirconia compared with titanium implants: a systematic review and meta-analysis. Clin Oral Investig 27:6279\u20136290","journal-title":"Clin Oral Investig"},{"key":"2409_CR4","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.dental.2006.06.025","volume":"23","author":"L Guehennec","year":"2007","unstructured":"Guehennec L (2007) Surface treatments of titanium dental implants for rapid osseointegration. Dent mater 23:844\u2013854","journal-title":"Dent mater"},{"key":"2409_CR5","doi-asserted-by":"publisher","first-page":"39","DOI":"10.11607\/prd.2663","volume":"36","author":"DS Thoma","year":"2016","unstructured":"Thoma DS, Cathomen E, H\u00e4mmerle CHF, H\u00fcsler J, Jung RE (2016) Discoloration of the peri-implant mucosa caused by zirconia and titanium implants. Int J Periodontics Restorative Dent 36:39\u201345","journal-title":"Int J Periodontics Restorative Dent"},{"key":"2409_CR6","doi-asserted-by":"publisher","first-page":"1413","DOI":"10.11607\/jomi.6077","volume":"32","author":"FS-L Amo","year":"2017","unstructured":"Amo FS-L, Rudek I, Wagner V, Martins M, O\u2019Valle F, Galindo-Moreno P, Giannobile WV, Wang H-L, Castilho RM (2017) Titanium activates the DNA damage response pathway in oral epithelial cells: a pilot study. Int J Oral Maxillofac Implants 32:1413\u201320","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR7","doi-asserted-by":"publisher","first-page":"109","DOI":"10.1016\/0300-5712(95)00033-X","volume":"24","author":"F Toumelin-Chemla","year":"1996","unstructured":"Toumelin-Chemla F, Rouelle F, Burdairon G (1996) Corrosive properties of fluoride-containing odontologic gels against titanium. J Dent 24:109\u2013115","journal-title":"J Dent"},{"key":"2409_CR8","doi-asserted-by":"publisher","first-page":"1403","DOI":"10.1007\/s00784-016-1853-9","volume":"20","author":"D Hashim","year":"2016","unstructured":"Hashim D, Cionca N, Courvoisier DS, Mombelli A (2016) A systematic review of the clinical survival of zirconia implants. Clin Oral Investig 20:1403\u20131417","journal-title":"Clin Oral Investig"},{"key":"2409_CR9","doi-asserted-by":"publisher","first-page":"667","DOI":"10.11607\/jomi.10142","volume":"38","author":"MJS Rem\u00edsio","year":"2023","unstructured":"Rem\u00edsio MJS, Borges T, Castro F, Alexandre Gehrke S, Fernandes JCH, Fernandes GVO (2023) Histologic osseointegration level comparing titanium and zirconia dental implants: meta-analysis of preclinical studies. Int J Oral Maxillofac Implants 38:667\u2013680","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR10","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1111\/j.1600-0501.2009.01785.x","volume":"20","author":"M Andreiotelli","year":"2009","unstructured":"Andreiotelli M, Wenz HJ, Kohal R (2009) Are ceramic implants a viable alternative to titanium implants? A systematic literature review. Clin Oral Implants Res 20:32\u201347","journal-title":"Clin Oral Implants Res"},{"key":"2409_CR11","doi-asserted-by":"publisher","first-page":"124","DOI":"10.1111\/j.1708-8208.2012.00454.x","volume":"16","author":"R Depprich","year":"2014","unstructured":"Depprich R, Naujoks C, Ommerborn M, Schwarz F, K\u00fcbler NR, Handschel J (2014) Current findings regarding zirconia implants. Clin Implant Dent Relat Res 16:124\u2013137","journal-title":"Clin Implant Dent Relat Res"},{"key":"2409_CR12","doi-asserted-by":"publisher","first-page":"686","DOI":"10.1186\/s12903-023-03370-8","volume":"23","author":"AR Alqahtani","year":"2023","unstructured":"Alqahtani AR, Desai SR, Patel JR, Alqhtani NR, Alqahtani AS, Heboyan A, Fernandes GVO, Mustafa M, Karobari MI (2023) Investigating the impact of diameters and thread designs on the biomechanics of short implants placed in D4 bone: a 3D finite element analysis. BMC Oral Health 23:686","journal-title":"BMC Oral Health"},{"key":"2409_CR13","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1111\/cid.12720","volume":"21","author":"J Lorenz","year":"2019","unstructured":"Lorenz J, Giulini N, H\u00f6lscher W, Schwiertz A, Schwarz F, Sader R (2019) Prospective controlled clinical study investigating long-term clinical parameters, patient satisfaction, and microbial contamination of zirconia implants. Clin Implant Dent Relat Res 21:263\u2013271","journal-title":"Clin Implant Dent Relat Res"},{"key":"2409_CR14","doi-asserted-by":"publisher","first-page":"313","DOI":"10.11607\/jomi.9886","volume":"38","author":"W Teixeira","year":"2023","unstructured":"Teixeira W, Nascimento C, Pereira A, Martins R, Mendon\u00e7a G, de Oliveira Fernandes GVO, Wang H-L, Pedrazzi V (2023) Bacterial leakage evaluation through DNA-DNA checkerboard hybridization technique in Morse taper implant-abutment connections: an in vitro study. Int J Oral Maxillofac Implants 38:313\u2013320","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR15","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1177\/0022034520949851","volume":"100","author":"GN Belibasakis","year":"2021","unstructured":"Belibasakis GN, Manoil D (2021) Microbial community-driven etiopathogenesis of peri-implantitis. J Dent Res 100:21\u201328","journal-title":"J Dent Res"},{"key":"2409_CR16","doi-asserted-by":"publisher","first-page":"78","DOI":"10.1016\/j.jdsr.2021.05.002","volume":"57","author":"M Wada","year":"2021","unstructured":"Wada M, Mameno T, Otsuki M, Kani M, Tsujioka Y, Ikebe K (2021) Prevalence and risk indicators for peri-implant diseases: a literature review. Jap Dental Sci Rev 57:78\u201384","journal-title":"Jap Dental Sci Rev"},{"key":"2409_CR17","doi-asserted-by":"publisher","first-page":"660","DOI":"10.11607\/jomi.9659","volume":"37","author":"BGS Martins","year":"2022","unstructured":"Martins BGS, Fernandes JCH, Martins AG, Castilho RM, Fernandes GVO (2022) Surgical and nonsurgical treatment protocols for peri-implantitis: an overview of systematic reviews. Int J Oral Maxillofac Implants 37:660\u2013676","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR18","doi-asserted-by":"publisher","first-page":"1075","DOI":"10.3390\/molecules28031075","volume":"28","author":"MA Alarc\u00f3n-S\u00e1nchez","year":"2023","unstructured":"Alarc\u00f3n-S\u00e1nchez MA, Heboyan A, Fernandes GVO, Castro-Alarc\u00f3n N, Romero-Castro NS (2023) Potential impact of prosthetic biomaterials on the periodontium: a comprehensive review. Molecules 28:1075","journal-title":"Molecules"},{"key":"2409_CR19","doi-asserted-by":"publisher","first-page":"e125","DOI":"10.11607\/jomi.5223","volume":"32","author":"B Elnayef","year":"2017","unstructured":"Elnayef B, Lazaro A, Su\u00e1rez-L\u00f3pez del Amo F, Galindo-Moreno P, Wang H-L, Gargallo-Albiol J, Hern\u00e1ndez-Alfaro F (2017) Zirconia implants as an alternative to titanium: a systematic review and meta-analysis. Int J Oral Maxillofac Implants 32:e125\u2013e134","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR20","doi-asserted-by":"publisher","first-page":"1587","DOI":"10.3390\/diagnostics13091587","volume":"13","author":"S Fuda","year":"2023","unstructured":"Fuda S, Martins BGS, Castro FC, Heboyan A, Gehrke SA, Fernandes JCH, Mello-Moura ACV, Fernandes GVO (2023) Marginal bone level and clinical parameter analysis comparing external hexagon and morse taper implants: a systematic review and meta-analysis. Diagnostics 13:1587","journal-title":"Diagnostics"},{"key":"2409_CR21","doi-asserted-by":"publisher","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","volume":"151","author":"D Moher","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG (2009) PRISMA group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151:264\u20139","journal-title":"Ann Intern Med"},{"key":"2409_CR22","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1472-6947-7-16","volume":"7","author":"C Schardt","year":"2007","unstructured":"Schardt C, Adams MB, Owens T, Keitz S, Fontelo P (2007) Utilization of the PICO framework to improve searching PubMed for clinical questions. BMC Med Inform Decis Mak 7:1\u20136","journal-title":"BMC Med Inform Decis Mak"},{"key":"2409_CR23","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1159\/000051263","volume":"12","author":"M Oremus","year":"2001","unstructured":"Oremus M, Wolfson C, Perrault A, Demers L, Momoli F, Moride Y (2001) Interrater reliability of the modified Jadad quality scale for systematic reviews of Alzheimer\u2019s disease drug trials. Dement Geriatr Cogn Disord 12:232\u2013236","journal-title":"Dement Geriatr Cogn Disord"},{"key":"2409_CR24","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1111\/j.1600-0501.2004.00983.x","volume":"15","author":"IK Karoussis","year":"2004","unstructured":"Karoussis IK, Br\u00e4gger U, Salvi GE, B\u00fcrgin W, Lang NP (2004) Effect of implant design on survival and success rates of titanium oral implants: a 10-year prospective cohort study of the ITI\u00ae dental implant system. Clin Oral Implants Res 15:8\u201317","journal-title":"Clin Oral Implants Res"},{"key":"2409_CR25","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1902\/jop.2009.080411","volume":"80","author":"M Venza","year":"2009","unstructured":"Venza M, Visalli M, Lo Giudice G, Cicciu M, Passi P, Teti D (2009) Changes in inflammatory mediators in peri-implant fluid after implant insertion. J Periodontol 80:297\u2013306","journal-title":"J Periodontol"},{"key":"2409_CR26","doi-asserted-by":"publisher","first-page":"780","DOI":"10.1111\/cid.12056","volume":"15","author":"V Chappuis","year":"2013","unstructured":"Chappuis V, Buser R, Br\u00e4gger U, Bornstein MM, Salvi GE, Buser D (2013) Long-term outcomes of dental implants with a titanium plasma-sprayed surface: a 20-year prospective case series study in partially edentulous patients. Clin Implant Dent Relat Res 15:780\u2013790","journal-title":"Clin Implant Dent Relat Res"},{"key":"2409_CR27","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1111\/clr.12272","volume":"25","author":"RB Osman","year":"2014","unstructured":"Osman RB, Swain MV, Atieh M, Ma S, Duncan W (2014) Ceramic implants (Y-TZP): are they a viable alternative to titanium implants for the support of overdentures? A randomized clinical trial. Clin Oral Implants Res 25:1366\u20131377","journal-title":"Clin Oral Implants Res"},{"key":"2409_CR28","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1111\/cid.12159","volume":"17","author":"A Siddiqi","year":"2015","unstructured":"Siddiqi A, Kieser JA, De Silva RK, Thomson WM, Duncan WJ (2015) Soft and hard tissue response to zirconia versus titanium one-piece implants placed in alveolar and palatal sites: a randomized control trial. Clin Implant Dent Relat Res 17:483\u2013496","journal-title":"Clin Implant Dent Relat Res"},{"key":"2409_CR29","doi-asserted-by":"publisher","first-page":"371","DOI":"10.1111\/clr.12342","volume":"26","author":"M Payer","year":"2015","unstructured":"Payer M, Heschl A, Koller M, Arnetzl G, Lorenzoni M, Jakse N (2015) All-ceramic restoration of zirconia two-piece implants\u2013a randomized controlled clinical trial. Clin Oral Implants Res 26:371\u2013376","journal-title":"Clin Oral Implants Res"},{"key":"2409_CR30","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/415029","volume":"2015","author":"AE Borgonovo","year":"2015","unstructured":"Borgonovo AE, Censi R, Vavassori V, Arnaboldi O, Maiorana C, Re D (2015) Zirconia implants in esthetic areas: 4-Year follow-up evaluation study. Int J Dent 2015:415029","journal-title":"Int J Dent"},{"key":"2409_CR31","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1111\/jcpe.12439","volume":"42","author":"F Schwarz","year":"2015","unstructured":"Schwarz F, John G, Hegewald A, Becker J (2015) Non-surgical treatment of peri-implant mucositis and peri-implantitis at zirconia implants: a prospective case series. J Clin Periodontol 42:783\u2013788","journal-title":"J Clin Periodontol"},{"key":"2409_CR32","doi-asserted-by":"publisher","first-page":"855","DOI":"10.11607\/jomi.4511","volume":"31","author":"J Holl\u00e4nder","year":"2016","unstructured":"Holl\u00e4nder J, Lorenz J, St\u00fcbinger S, H\u00f6lscher W, Heidemann D, Ghanaati S, Sader R (2016) Zirconia dental implants: investigation of clinical parameters, patient satisfaction, and microbial contamination. Int J Oral Maxillofac Implants 31:855\u2013864","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR33","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1186\/s40729-017-0101-7","volume":"3","author":"T Horikawa","year":"2017","unstructured":"Horikawa T, Odatsu T, Itoh T, Soejima Y, Morinaga H, Abe N, Tsuchiya N, Iijima T, Sawase T (2017) Retrospective cohort study of rough-surface titanium implants with at least 25 years\u2019 function. Int J Implant Dent 3:42","journal-title":"Int J Implant Dent"},{"key":"2409_CR34","doi-asserted-by":"publisher","first-page":"114","DOI":"10.1111\/jcpe.12815","volume":"45","author":"R Kohal","year":"2018","unstructured":"Kohal R, Spies BC, Bauer A, Butz F (2018) One-piece zirconia oral implants for single-tooth replacement: three-year results from a long-term prospective cohort study. J Clin Periodontol 45:114\u2013124","journal-title":"J Clin Periodontol"},{"key":"2409_CR35","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1902\/jop.2016.160524","volume":"88","author":"LM Safioti","year":"2017","unstructured":"Safioti LM, Kotsakis GA, Pozhitkov AE, Chung WO, Daubert DM (2017) Increased levels of dissolved titanium are associated with peri-implantitis\u2013a cross-sectional study. J Periodontol 88:436\u2013442","journal-title":"J Periodontol"},{"issue":"217","key":"2409_CR36","first-page":"222","volume":"33","author":"K Kniha","year":"2018","unstructured":"Kniha K, Milz S, Kniha H, Ayoub N, H\u00f6lzle F, Modabber A (2018) Peri-implant crestal bone changes around zirconia implants in periodontally healthy and compromised patients. Int J Oral Maxillofac Implants 33(217):222","journal-title":"Int J Oral Maxillofac Implants"},{"key":"2409_CR37","doi-asserted-by":"publisher","first-page":"538","DOI":"10.1111\/jerd.12414","volume":"30","author":"AE Rodriguez","year":"2018","unstructured":"Rodriguez AE, Monzavi M, Yokoyama CL, Nowzari H (2018) Zirconia dental implants: a clinical and radiographic evaluation. J Esthet Restor Dent 30:538\u2013544","journal-title":"J Esthet Restor Dent"},{"key":"2409_CR38","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1111\/clr.13576","volume":"31","author":"M Koller","year":"2020","unstructured":"Koller M, Steyer E, Theisen K, Stagnell S, Jakse N, Payer M (2020) Two-piece zirconia versus titanium implants after 80 months: clinical outcomes from a prospective randomized pilot trial. Clin Oral Implants Res 31:388\u2013396","journal-title":"Clin Oral Implants Res"},{"key":"2409_CR39","doi-asserted-by":"publisher","first-page":"721","DOI":"10.1111\/jcpe.13411","volume":"48","author":"SP Bienz","year":"2021","unstructured":"Bienz SP, Hilbe M, H\u00fcsler J, Thoma DS, H\u00e4mmerle CHF, Jung RE (2021) Clinical and histological comparison of the soft tissue morphology between zirconia and titanium dental implants under healthy and experimental mucositis conditions\u2014a randomized controlled clinical trial. J Clin Periodontol 48:721\u2013733","journal-title":"J Clin Periodontol"},{"key":"2409_CR40","doi-asserted-by":"publisher","first-page":"9625","DOI":"10.3390\/app11209625","volume":"11","author":"F Delucchi","year":"2021","unstructured":"Delucchi F, Pozzetti E, Bagnasco F, Pesce P, Baldi D, Pera F et al (2021) Peri-implant tissue behaviour next to different titanium surfaces: 16-year post-trial follow-up. Appl Sci 11:9625","journal-title":"Appl Sci"},{"key":"2409_CR41","doi-asserted-by":"publisher","first-page":"S383","DOI":"10.4103\/jpbs.JPBS_815_20","volume":"13","author":"J Rasul","year":"2021","unstructured":"Rasul J, Thakur MK, Maheshwari B, Aga N, Kumar H, Mahajani M (2021) Assessment of titanium level in submucosal plaque around healthy implants and implants with peri-implantitis: a clinical study. J Pharm Bioallied Sci 13:S383\u2013S386","journal-title":"J Pharm Bioallied Sci"},{"key":"2409_CR42","first-page":"590","volume":"53","author":"F De Pascalis","year":"2022","unstructured":"De Pascalis F (2022) Soft tissue integration with a hybrid abutment using the \u201cone abutment\u2013one time\u201d therapeutic protocol: case series. Quintessence Int (Berl) 53:590","journal-title":"Quintessence Int (Berl)"},{"issue":"90","key":"2409_CR43","first-page":"176","volume":"2022","author":"S Ivanovski","year":"2000","unstructured":"Ivanovski S, Bartold PM, Huang Y (2000) The role of foreign body response in peri-implantitis: what is the evidence? Periodontol 2022(90):176\u2013185","journal-title":"Periodontol"}],"container-title":["Journal of Maxillofacial and Oral Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12663-024-02409-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12663-024-02409-9\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12663-024-02409-9.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T04:22:17Z","timestamp":1757132537000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12663-024-02409-9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,10]]},"references-count":43,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,8]]}},"alternative-id":["2409"],"URL":"https:\/\/doi.org\/10.1007\/s12663-024-02409-9","relation":{},"ISSN":["0972-8279","0974-942X"],"issn-type":[{"value":"0972-8279","type":"print"},{"value":"0974-942X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,10]]},"assertion":[{"value":"4 September 2024","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"1 December 2024","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"10 December 2024","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no conflict of interest.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"Not Applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical Approval and Consent to Participate"}},{"value":"Not Applicable.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to Publication"}}]}}