{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:32:54Z","timestamp":1778542374480,"version":"3.51.4"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"3","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Indian J Gastroenterol"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1007\/s12664-012-0201-5","type":"journal-article","created":{"date-parts":[[2012,7,5]],"date-time":"2012-07-05T13:39:06Z","timestamp":1341495546000},"page":"111-115","source":"Crossref","is-referenced-by-count":28,"title":["Time trends in epidemiology of peptic ulcer disease in India over two decades"],"prefix":"10.1007","volume":"31","author":[{"given":"Amit Kumar","family":"Dutta","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashok","family":"Chacko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avinash","family":"Balekuduru","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manoj Kumar","family":"Sahu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajith Kattiparambil","family":"Gangadharan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2012,7,6]]},"reference":[{"key":"201_CR1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000070394","volume":"67","author":"J Regula","year":"2003","unstructured":"Regula J, Hennig E, Burzykowski T, et al. Multivariate analysis of risk factors for development of duodenal ulcer in Helicobacter pylori-infected patients. Digestion. 2003;67:25\u201331.","journal-title":"Digestion."},{"key":"201_CR2","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1136\/gut.52.2.186","volume":"52","author":"S Rosenstock","year":"2003","unstructured":"Rosenstock S, Jorgensen T, Bonnevie O, Andersen L. Risk factors for peptic ulcer disease: a population based prospective cohort study comprising 2416 Danish adults. Gut. 2003;52:186\u201393.","journal-title":"Gut."},{"key":"201_CR3","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.clim.2008.07.009","volume":"129","author":"OA Trejo-de la","year":"2008","unstructured":"la Trejo-de OA, Torres J, Perez-Rodriguez M, et al. TLR4 single-nucleotide polymorphisms alter mucosal cytokine and chemokine patterns in Mexican patients with Helicobacter pylori-associated gastroduodenal diseases. Clin Immunol. 2008;129:333\u201340.","journal-title":"Clin Immunol."},{"key":"201_CR4","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1136\/gut.26.8.789","volume":"26","author":"JH McIntosh","year":"1985","unstructured":"McIntosh JH, Byth K, Piper DW. Environmental factors in aetiology of chronic gastric ulcer: a case control study of exposure variables before the first symptoms. Gut. 1985;26:789\u201398.","journal-title":"Gut."},{"issue":"Suppl 5","key":"201_CR5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF02989226","volume":"28","author":"SK Lam","year":"1993","unstructured":"Lam SK. Epidemiology and genetics of peptic ulcer. Gastroenterol Jpn. 1993;28 Suppl 5:145\u201357.","journal-title":"Gastroenterol Jpn."},{"key":"201_CR6","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1053\/bega.1999.0058","volume":"14","author":"SK Lam","year":"2000","unstructured":"Lam SK. Differences in peptic ulcer between East and West. Baillieres Best Pract Res Clin Gastroenterol. 2000;14:41\u201352.","journal-title":"Baillieres Best Pract Res Clin Gastroenterol."},{"key":"201_CR7","first-page":"285","volume":"26","author":"A Sood","year":"2007","unstructured":"Sood A, Midha V. Epidemiology of inflammatory bowel disease in Asia. Indian J Gastroenterol. 2007;26:285\u20139.","journal-title":"Indian J Gastroenterol."},{"key":"201_CR8","doi-asserted-by":"crossref","unstructured":"Tack J. Dyspepsia. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran\u2019s gastrointestinal and liver disease pathophysiology, diagnosis, management, Ninth edition, Gurgaon, Elsevier Publication; 2010. pp 183.","DOI":"10.1016\/B978-1-4160-6189-2.00013-5"},{"key":"201_CR9","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/ajg.2009.706","volume":"105","author":"RM Zagari","year":"2010","unstructured":"Zagari RM, Law GR, Fuccio L, Pozzato P, Forman D, Bazzoli F. Dyspeptic symptoms and endoscopic findings in the community: the Loiano-Monghidoro study. Am J Gastroenterol. 2010;105:565\u201371.","journal-title":"Am J Gastroenterol."},{"key":"201_CR10","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1016\/0016-5085(93)90142-Y","volume":"105","author":"NJ Talley","year":"1993","unstructured":"Talley NJ, Weaver AL, Tesmer DL, Zinsmeister AR. Lack of discriminant value of dyspepsia subgroups in patients referred for upper endoscopy. Gastroenterology. 1993;105:1378\u201386.","journal-title":"Gastroenterology."},{"key":"201_CR11","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1136\/gut.31.9.989","volume":"31","author":"B Bernersen","year":"1990","unstructured":"Bernersen B, Johnsen R, Straume B, Burhol PG, Jenssen TG, Stakkevold PA. Towards a true prevalence of peptic ulcer: the Sorreisa gastrointestinal disorder study. Gut. 1990;31:989\u201392.","journal-title":"Gut."},{"key":"201_CR12","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2036.2004.01897.x","volume":"19","author":"HB El-Serag","year":"2004","unstructured":"El-Serag HB, Talley NJ. Systemic review: the prevalence and clinical course of functional dyspepsia. Aliment Pharmacol Ther. 2004;19:643\u201354.","journal-title":"Aliment Pharmacol Ther."},{"issue":"Suppl 4","key":"201_CR13","doi-asserted-by":"crossref","first-page":"iv10","DOI":"10.1136\/gut.50.suppl_4.iv10","volume":"50","author":"P Moayyedi","year":"2002","unstructured":"Moayyedi P, Mason J. Clinical and economic consequences of dyspepsia in the community. Gut. 2002;50 Suppl 4:iv10\u20132.","journal-title":"Gut"},{"issue":"Suppl 2","key":"201_CR14","doi-asserted-by":"crossref","first-page":"II37","DOI":"10.1136\/gut.45.2008.ii37","volume":"45","author":"NJ Talley","year":"1999","unstructured":"Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, Tytgat GN. Functional gastroduodenal disorders. Gut. 1999;45 Suppl 2:II37\u201342.","journal-title":"Gut"},{"key":"201_CR15","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.43.3.327","volume":"43","author":"HB el-Serag","year":"1998","unstructured":"el-Serag HB, Sonnenberg A. Opposing time trends of peptic ulcer and reflux disease. Gut. 1998;43:327\u201333.","journal-title":"Gut."},{"key":"201_CR16","doi-asserted-by":"crossref","first-page":"1423","DOI":"10.1111\/j.1365-2036.2007.03340.x","volume":"25","author":"D Manuel","year":"2007","unstructured":"Manuel D, Cutler A, Goldstein J, Fennerty MB, Brown K. Decreasing prevalence combined with increasing eradication of Helicobacter pylori infection in the United States has not resulted in fewer hospital admissions for peptic ulcer disease-related complications. Aliment Pharmacol Ther. 2007;25:1423\u20137.","journal-title":"Aliment Pharmacol Ther."},{"key":"201_CR17","doi-asserted-by":"crossref","first-page":"189","DOI":"10.3109\/00365528509089655","volume":"20","author":"H Ostensen","year":"1985","unstructured":"Ostensen H, Gudmundsen TE, Bolz KD, Burhol PG, Bonnevie O. The incidence of gastric ulcer and duodenal ulcer in north Norway. A prospective epidemiological study. Scand J Gastroenterol. 1985;20:189\u201392.","journal-title":"Scand J Gastroenterol"},{"key":"201_CR18","doi-asserted-by":"crossref","first-page":"81","DOI":"10.5694\/j.1326-5377.1984.tb132708.x","volume":"141","author":"TB Hugh","year":"1984","unstructured":"Hugh TB, Coleman MJ, McNamara ME, Norman JR, Howell C. Epidemiology of peptic ulcer in Australia. A study based on government statistics in four states. Med J Aust. 1984;141:81\u20135.","journal-title":"Med J Aust."},{"key":"201_CR19","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1136\/gut.20.4.329","volume":"20","author":"F Tovey","year":"1979","unstructured":"Tovey F. Peptic ulcer in India and Bangladesh. Gut. 1979;20:329\u201347.","journal-title":"Gut."},{"key":"201_CR20","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1136\/gut.30.7.930","volume":"30","author":"MS Khuroo","year":"1989","unstructured":"Khuroo MS, Mahajan R, Zargar SA, Javid G, Munshi S. Prevalence of peptic ulcer in India: an endoscopic and epidemiological study in urban Kashmir. Gut. 1989;30:930\u20134.","journal-title":"Gut."},{"key":"201_CR21","first-page":"212","volume":"40","author":"W Ahmed","year":"1990","unstructured":"Ahmed W, Qureshi H, Alam SE, Zuberi SJ. Pattern of duodenal ulcer in Karachi. J Pak Med Assoc. 1990;40:212\u20135.","journal-title":"J Pak Med Assoc."},{"key":"201_CR22","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1097\/00004836-199110000-00021","volume":"13","author":"MK Goenka","year":"1991","unstructured":"Goenka MK, Kochhar R, Ghosh P, Mehta SK. Changing pattern of peptic ulcer in India. An endoscopic study of 1,188 ulcer patients. J Clin Gastroenterol. 1991;13:575\u20139.","journal-title":"J Clin Gastroenterol."},{"key":"201_CR23","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1111\/j.1440-1746.2005.03719.x","volume":"20","author":"SN Wong","year":"2005","unstructured":"Wong SN, Sollano JD, Chan MM, et al. Changing trends in peptic ulcer prevalence in a tertiary care setting in the Philippines: a seven-year study. J Gastroenterol Hepatol. 2005;20:628\u201332.","journal-title":"J Gastroenterol Hepatol."},{"key":"201_CR24","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1111\/j.1365-2036.2009.03930.x","volume":"29","author":"KL Goh","year":"2009","unstructured":"Goh KL, Wong HT, Lim CH, Rosaida MS. Time trends in peptic ulcer, erosive reflux oesophagitis, gastric and oesophageal cancers in a multiracial Asian population. Aliment Pharmacol Ther. 2009;29:774\u201380.","journal-title":"Aliment Pharmacol Ther."},{"key":"201_CR25","first-page":"260","volume":"31","author":"JV Cherian","year":"2010","unstructured":"Cherian JV, Somasundaram A, Ramalingam S, Jayanthi V. Peptic ulcer disease in India\u2013a 16\u00a0year trend analysis. Trop Gastroenterol. 2010;31:260\u20135.","journal-title":"Trop Gastroenterol."},{"key":"201_CR26","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1007\/s10620-007-0028-6","volume":"53","author":"HJ Jang","year":"2008","unstructured":"Jang HJ, Choi MH, Shin WG, et al. Has peptic ulcer disease changed during the past ten years in Korea? A prospective multi-center study. Dig Dis Sci. 2008;53:1527\u201331.","journal-title":"Dig Dis Sci."},{"key":"201_CR27","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1097\/MEG.0b013e32830e285a","volume":"21","author":"JI Kim","year":"2009","unstructured":"Kim JI, Kim SG, Kim N, et al. Changing prevalence of upper gastrointestinal disease in 28 893 Koreans from 1995 to 2005. Eur J Gastroenterol Hepatol. 2009;21:787\u201393.","journal-title":"Eur J Gastroenterol Hepatol."},{"key":"201_CR28","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1002\/pds.988","volume":"13","author":"DP Devi","year":"2004","unstructured":"Devi DP, Sushma M, Guido S. Drug-induced upper gastrointestinal disorders requiring hospitalization: a five-year study in a South Indian hospital. Pharmacoepidemiol Drug Saf. 2004;13:859\u201362.","journal-title":"Pharmacoepidemiol Drug Saf."},{"key":"201_CR29","doi-asserted-by":"crossref","first-page":"16","DOI":"10.3109\/00365529709025057","volume":"32","author":"HO Hein","year":"1997","unstructured":"Hein HO, Suadicani P, Gyntelberg F. Genetic markers for peptic ulcer. A study of 3387 men aged 54 to 74\u00a0years: the Copenhagen Male Study. Scand J Gastroenterol. 1997;32:16\u201321.","journal-title":"Scand J Gastroenterol"},{"key":"201_CR30","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1093\/ije\/dyl093","volume":"35","author":"A Sonnenberg","year":"2006","unstructured":"Sonnenberg A. Causes underlying the birth-cohort phenomenon of peptic ulcer: analysis of mortality data 1911\u20132000, England and Wales. Int J Epidemiol. 2006;35:1090\u20137.","journal-title":"Int J Epidemiol."},{"key":"201_CR31","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1111\/j.1365-2036.2005.02554.x","volume":"22","author":"B Xia","year":"2005","unstructured":"Xia B, Xia HH, Ma CW, et al. Trends in the prevalence of peptic ulcer disease and Helicobacter pylori infection in family physician-referred uninvestigated dyspeptic patients in Hong Kong. Aliment Pharmacol Ther. 2005;22:243\u20139.","journal-title":"Aliment Pharmacol Ther."},{"key":"201_CR32","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1111\/j.1365-2036.1993.tb00118.x","volume":"7","author":"SC Misra","year":"1993","unstructured":"Misra SC, Dasarathy S, Sharma MP. Omeprazole versus famotidine in the healing and relapse of duodenal ulcer. Aliment Pharmacol Ther. 1993;7:443\u20139.","journal-title":"Aliment Pharmacol Ther."},{"key":"201_CR33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1440-1746.1998.tb00537.x","volume":"13","author":"SK Lam","year":"1998","unstructured":"Lam SK, Talley NJ. Report of the 1997 Asia Pacific Consensus Conference on the management of Helicobacter pylori infection. J Gastroenterol Hepatol. 1998;13:1\u201312.","journal-title":"J Gastroenterol Hepatol."},{"key":"201_CR34","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/gut.22.4.327","volume":"22","author":"MG Moshal","year":"1981","unstructured":"Moshal MG, Spitaels JM, Robbs JV, MacLeod IN, Good CJ. Eight-year experience with 3392 endoscopically proven duodenal ulcers in Durban, 1972\u201379. Rise and fall of duodenal ulcers and a theory of changing dietary and social factors. Gut. 1981;22:327\u201331.","journal-title":"Gut"},{"key":"201_CR35","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1136\/gut.27.3.239","volume":"27","author":"D Hollander","year":"1986","unstructured":"Hollander D, Tarnawski A. Dietary essential fatty acids and the decline in peptic ulcer disease\u2013a hypothesis. Gut. 1986;27:239\u201342.","journal-title":"Gut."},{"key":"201_CR36","first-page":"36","volume":"20","author":"A Jain","year":"1999","unstructured":"Jain A, Buddhiraja S, Khurana B, et al. Risk factors for duodenal ulcer in north India. Trop Gastroenterol. 1999;20:36\u20139.","journal-title":"Trop Gastroenterol."},{"key":"201_CR37","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/MCG.0b013e3180318ac5","volume":"42","author":"G Talamini","year":"2008","unstructured":"Talamini G, Tommasi M, Amadei V, et al. Risk factors of peptic ulcer in 4943 inpatients. J Clin Gastroenterol. 2008;42:373\u201380.","journal-title":"J Clin Gastroenterol."}],"container-title":["Indian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12664-012-0201-5.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s12664-012-0201-5\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s12664-012-0201-5","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T08:09:33Z","timestamp":1594368573000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s12664-012-0201-5"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":37,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["201"],"URL":"https:\/\/doi.org\/10.1007\/s12664-012-0201-5","relation":{},"ISSN":["0254-8860","0975-0711"],"issn-type":[{"value":"0254-8860","type":"print"},{"value":"0975-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,6]]}}}