{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T16:38:47Z","timestamp":1781800727534,"version":"3.54.5"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Indian J Gastroenterol"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1007\/s12664-022-01308-6","type":"journal-article","created":{"date-parts":[[2023,2,13]],"date-time":"2023-02-13T13:19:56Z","timestamp":1676294396000},"page":"53-63","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Utility of high-flow nasal oxygen in comparison to conventional oxygen therapy during upper gastrointestinal endoscopic procedures under sedation: A systematic review and meta-analyses"],"prefix":"10.1007","volume":"42","author":[{"given":"Puneet","family":"Khanna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damarla","family":"Haritha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Das","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0497-9909","authenticated-orcid":false,"given":"Soumya","family":"Sarkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avishek","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,2,13]]},"reference":[{"key":"1308_CR1","doi-asserted-by":"publisher","first-page":"319","DOI":"10.1016\/S0016-5107(92)70424-6","volume":"38","author":"GD Bell","year":"1992","unstructured":"Bell GD, Quine A, Antrobus JH, et al. Upper gastrointestinal endoscopy: a prospective randomized study comparing continuous supplemental oxygen via the nasal or oral route. Gastrointest Endosc. 1992;38:319\u201325.","journal-title":"Gastrointest Endosc."},{"key":"1308_CR2","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.tgie.2009.09.005","volume":"11","author":"JH Atkins","year":"2009","unstructured":"Atkins JH. Ventilation strategies in gastrointestinal endoscopy. Tech Gastrointest Endosc. 2009;11:192\u20136.","journal-title":"Tech Gastrointest Endosc."},{"key":"1308_CR3","doi-asserted-by":"publisher","first-page":"527","DOI":"10.4097\/kja.19174","volume":"72","author":"HJ Kim","year":"2019","unstructured":"Kim HJ, Asai T. High-flow nasal oxygenation for anesthetic management. Korean J Anesthesiol. 2019;72:527\u201347.","journal-title":"Korean J Anesthesiol."},{"key":"1308_CR4","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1016\/j.bja.2017.11.010","volume":"120","author":"T Renda","year":"2018","unstructured":"Renda T, Corrado A, Iskandar G, Pelaia G, Abdalla K, Navalesi P. High-flow nasal oxygen therapy in intensive care and anaesthesia. Br J Anaesth. 2018;120:18\u201327.","journal-title":"Br J Anaesth."},{"key":"1308_CR5","doi-asserted-by":"publisher","first-page":"10398","DOI":"10.3748\/wjg.v22.i47.10398","volume":"22","author":"R Schumann","year":"2016","unstructured":"Schumann R, Natov NS, Rocuts-Martinez KA, et al. High-flow nasal oxygen availability for sedation decreases the use of general anesthesia during endoscopic retrograde cholangiopancreatography and endoscopic ultrasound. World J Gastroenterol. 2016;22:10398\u2013405.","journal-title":"World J Gastroenterol."},{"key":"1308_CR6","unstructured":"Rex DK, Deenadayalu VP, Eid E, et al. Endoscopist-directed administration of propofol: a worldwide safety experience.Gastroenterology. 2009;137:1229-37;quiz 1518-9."},{"key":"1308_CR7","doi-asserted-by":"publisher","first-page":"161","DOI":"10.5946\/ce.2016.019","volume":"50","author":"B Goudra","year":"2017","unstructured":"Goudra B, Nuzat A, Singh PM, Borle A, Carlin A, Gouda G. Association between type of sedation and the adverse events associated with gastrointestinal endoscopy: an analysis of 5 years\u2019 data from a tertiary center in the USA. Clin Endosc. 2017;50:161\u20139.","journal-title":"Clin Endosc."},{"key":"1308_CR8","doi-asserted-by":"publisher","first-page":"66","DOI":"10.1097\/LBR.0000000000000533","volume":"26","author":"JS Bain","year":"2019","unstructured":"Service JA, Bain JS, Gardner CP, McNarry AF. Prospective experience of high-flow nasal oxygen during bronchoscopy in 182 patients: a feasibility study. J Bronchology Interv Pulmonol. 2019;26:66\u201370.","journal-title":"J Bronchology Interv Pulmonol."},{"key":"1308_CR9","doi-asserted-by":"publisher","first-page":"1058","DOI":"10.1016\/j.joms.2014.12.020","volume":"73","author":"T Sago","year":"2015","unstructured":"Sago T, Harano N, Chogyoji Y, Nunomaki M, Shiiba S, Watanabe S. A nasal high-flow system prevents hypoxia in dental patients under intravenous sedation. J Oral Maxillofac Surg. 2015;73:1058\u201364.","journal-title":"J Oral Maxillofac Surg."},{"key":"1308_CR10","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1093\/bja\/aev262","volume":"115","author":"S Badiger","year":"2015","unstructured":"Badiger S, John M, Fearnley RA, Ahmad I. Optimizing oxygenation and intubation conditions during awake fibre-optic intubation using a high-flow nasal oxygen-delivery system. Br J Anaesth. 2015;115:629\u201332.","journal-title":"Br J Anaesth"},{"key":"1308_CR11","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1097\/LBR.0000000000000719","volume":"28","author":"M Irfan","year":"2021","unstructured":"Irfan M, Ahmed M, Breen D. Assessment of high flow nasal cannula oxygenation in endobronchial ultrasound bronchoscopy: a randomized controlled trial. J Bronchology Interv Pulmonol. 2021;28:130\u20137.","journal-title":"J Bronchology Interv Pulmonol."},{"key":"1308_CR12","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1136\/thoraxjnl-2021-217116","volume":"77","author":"F Longhini","year":"2022","unstructured":"Longhini F, Pelaia C, Garofalo E, et al. High-flow nasal cannula oxygen therapy for outpatients undergoing flexible bronchoscopy: a randomised controlled trial. Thorax. 2022;77:58\u201364.","journal-title":"Thorax."},{"key":"1308_CR13","doi-asserted-by":"crossref","unstructured":"Lucangelo U, Vassallo FG, Marras E, et al. High-flow nasal interface improves oxygenation in patients undergoing bronchoscopy. Crit Care Res Pract. 2012;2012:506382.","DOI":"10.1155\/2012\/506382"},{"key":"1308_CR14","doi-asserted-by":"crossref","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6:e1000097.","DOI":"10.1371\/journal.pmed.1000097"},{"key":"1308_CR15","doi-asserted-by":"publisher","first-page":"i4919","DOI":"10.1136\/bmj.i4919","volume":"355","author":"JAC Sterne","year":"2016","unstructured":"Sterne JAC, Hern\u00e1n MA, Reeves BC, et al. ROBINS-I: a tool for assessing risk of bias in non-randomized studies of interventions. BMJ. 2016;355:i4919.","journal-title":"BMJ"},{"key":"1308_CR16","doi-asserted-by":"crossref","unstructured":"Sterne JAC, Savovi\u0107 J, Page MJ, et al. RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019;366:l4898","DOI":"10.1136\/bmj.l4898"},{"key":"1308_CR17","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.jclinepi.2016.07.001","volume":"79","author":"SL Norris","year":"2016","unstructured":"Norris SL, Meerpohl JJ, Akl EA, et al. The skills and experience of GRADE methodologists can be assessed with a simple tool. J Clin Epidemiol. 2016;79:150-158.e1.","journal-title":"J Clin Epidemiol."},{"key":"1308_CR18","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","volume":"64","author":"G Guyatt","year":"2011","unstructured":"Guyatt G, Oxman AD, Akl EA, et al. GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables. J Clin Epidemiol. 2011;64:383\u201394.","journal-title":"J Clin Epidemiol."},{"key":"1308_CR19","doi-asserted-by":"crossref","unstructured":"Balshem H, Helfand M, Sch\u00fcnemann HJ, et al. GRADE guidelines: 3. Rating the quality of evidence. J Clin Epidemiol. 2011;64:401\u20136.\u00a0","DOI":"10.1016\/j.jclinepi.2010.07.015"},{"key":"1308_CR20","doi-asserted-by":"crossref","unstructured":"Cumpston M, Li T, Page MJ, et al. Updated guidance for trusted systematic reviews: a new edition of the Cochrane Handbook for Systematic Reviews of Interventions. Cochrane Database Syst Rev. 2019;10:ED000142.","DOI":"10.1002\/14651858.ED000142"},{"key":"1308_CR21","doi-asserted-by":"crossref","unstructured":"Nay MA, Fromont L, Eugene A, et al. High-flow nasal oxygenation or standard oxygenation for gastrointestinal endoscopy with sedation in patients at risk of hypoxaemia: a multicentre randomised controlled trial (ODEPHI trial). Br J Anaesth. 2021;127:133\u201342.","DOI":"10.1016\/j.bja.2021.03.020"},{"key":"1308_CR22","doi-asserted-by":"crossref","unstructured":"Mazzeffi MA, Petrick KM, Magder L, et al. High-flow nasal cannula oxygen in patients having anesthesia for advanced esophagogastroduodenoscopy: HIFLOW-ENDO, a randomized clinical trial. Anesth Analg. 2021;132:743\u201351.","DOI":"10.1213\/ANE.0000000000004837"},{"key":"1308_CR23","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1007\/s12630-020-01883-2","volume":"68","author":"SH Kim","year":"2021","unstructured":"Kim SH, Bang S, Lee KY, et al. Comparison of high flow nasal oxygen and conventional nasal cannula during gastrointestinal endoscopic sedation in the prone position: a randomized trial. Can J Anaesth. 2021;68:460\u20136.","journal-title":"Can J Anaesth"},{"key":"1308_CR24","doi-asserted-by":"publisher","first-page":"4206795","DOI":"10.1155\/2019\/4206795","volume":"2019","author":"WN Teng","year":"2019","unstructured":"Teng WN, Ting CK, Wang YT, et al. High-flow nasal cannula and mandibular advancement bite block decrease hypoxic events during sedative esophagogastroduodenoscopy: a randomized clinical trial. Biomed Res Int. 2019;2019:4206795.","journal-title":"Biomed Res Int."},{"key":"1308_CR25","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1016\/j.gie.2019.06.033","volume":"90","author":"Y Lin","year":"2019","unstructured":"Lin Y, Zhang X, Li L, et al. High-flow nasal cannula oxygen therapy and hypoxia during gastroscopy with propofol sedation: a randomized multicenter clinical trial. Gastrointest Endosc. 2019;90:591\u2013601.","journal-title":"Gastrointest Endosc."},{"key":"1308_CR26","doi-asserted-by":"publisher","first-page":"4154","DOI":"10.1007\/s10620-021-07272-z","volume":"67","author":"MJ Lee","year":"2022","unstructured":"Lee MJ, Cha B, Park JS, et al. Impact of high-flow nasal cannula oxygenation on the prevention of hypoxia during endoscopic retrograde cholangiopancreatography in elderly patients: a randomized clinical trial. Dig Dis Sci. 2022;67:4154\u201360.","journal-title":"Dig Dis Sci."},{"key":"1308_CR27","doi-asserted-by":"crossref","unstructured":"Shukla K, Parikh B, Kumar A, Nakra M. Comparative evaluation of efficacy of oxygenation using high flow nasal cannula vs. conventional nasal cannula during procedural sedation for endoscopic ultrasound: a pilot study. J Anaesthesiol Clin Pharmacol. 2021;37:648\u201354.\u00a0","DOI":"10.4103\/joacp.JOACP_371_20"},{"key":"1308_CR28","doi-asserted-by":"crossref","unstructured":"Thiruvenkatarajan V, Dharmalingam A, Arenas G, et al. Effect of high-flow vs. low-flow nasal plus mouthguard oxygen therapy on hypoxaemia during sedation: a multicentre randomised controlled trial. Anaesthesia. 2022;77:46\u201353.\u00a0","DOI":"10.1111\/anae.15527"},{"key":"1308_CR29","unstructured":"Benatar PF, Galaviz ODA, Ch\u00e1vez RMA, et al. High-flow nasal cannula versus conventional oxygen therapy for patients undergoing gastrointestinal endoscopy. An Med Asoc Med Hosp ABC. 2017;62:187\u201391."},{"issue":"1","key":"1308_CR30","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/s40001-022-00661-8","volume":"27","author":"YX Zhang","year":"2022","unstructured":"Zhang YX, He XX, Chen YP, Yang S. The effectiveness of high-flow nasal cannula during sedated digestive endoscopy: a systematic review and meta-analysis. Eur J Med Res. 2022;27:30.","journal-title":"Eur J Med Res"},{"key":"1308_CR31","doi-asserted-by":"publisher","first-page":"3860","DOI":"10.3390\/jcm11133860","volume":"11","author":"CC Lee","year":"2022","unstructured":"Lee CC, Ju TR, Lai PC, Lin HT, Huang YT. Should we use high-flow nasal cannula in patients receiving gastrointestinal endoscopies? Critical appraisals through updated meta-analyses with multiple methodologies and depiction of certainty of evidence. J Clin Med. 2022;11:3860.","journal-title":"J Clin Med."},{"key":"1308_CR32","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1080\/17476348.2022.2042256","volume":"16","author":"M Doulberis","year":"2022","unstructured":"Doulberis M, Sampsonas F, Papaefthymiou A, et al. High-flow versus conventional nasal cannula oxygen supplementation therapy and risk of hypoxia in gastrointestinal endoscopies: a systematic review and meta-analysis. Expert Rev Respir Med. 2022;16:323\u201332.","journal-title":"Expert Rev Respir Med."},{"key":"1308_CR33","doi-asserted-by":"publisher","first-page":"103429","DOI":"10.1016\/j.resp.2020.103429","volume":"277","author":"G Mishima","year":"2020","unstructured":"Mishima G, Sanuki T, Revie J, et al. Nasal high flow improves ventilation during propofol sedation: a randomized cross-over study in healthy volunteers. Respir Physiol Neurobiol. 2020;277:103429.","journal-title":"Respir Physiol Neurobiol"},{"key":"1308_CR34","doi-asserted-by":"publisher","first-page":"350","DOI":"10.1038\/s41598-020-79798-7","volume":"11","author":"B Cha","year":"2021","unstructured":"Cha B, Lee MJ, Park JS, et al. Clinical efficacy of high-flow nasal oxygen in patients undergoing ERCP under sedation. Sci Rep. 2021;11:350.","journal-title":"Sci Rep."},{"key":"1308_CR35","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1097\/00003246-199601000-00007","volume":"24","author":"CW Hanson 3rd","year":"1996","unstructured":"Hanson CW 3rd, Marshall BE, Frasch HF, Marshall C. Causes of hypercarbia with oxygen therapy in patients with chronic obstructive pulmonary disease. Crit Care Med. 1996;24:23\u20138.","journal-title":"Crit Care Med"},{"key":"1308_CR36","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1186\/cc11475","volume":"16","author":"WF Abdo","year":"2012","unstructured":"Abdo WF, Heunks LM. Oxygen-induced hypercapnia in COPD: myths and facts. Crit Care. 2012;16:323.","journal-title":"Crit Care"},{"key":"1308_CR37","doi-asserted-by":"publisher","first-page":"2706","DOI":"10.1002\/ppul.24975","volume":"55","author":"D Klotz","year":"2020","unstructured":"Klotz D, Seifert V, Baumgartner J, Teufel U, Fuchs H. High-flow nasal cannula vs standard respiratory care in pediatric procedural sedation: a randomized controlled pilot trial. Pediatr Pulmonol. 2020;55:2706\u201312.","journal-title":"Pediatr Pulmonol."}],"container-title":["Indian Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12664-022-01308-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12664-022-01308-6\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12664-022-01308-6.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T04:03:45Z","timestamp":1744171425000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12664-022-01308-6"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["1308"],"URL":"https:\/\/doi.org\/10.1007\/s12664-022-01308-6","relation":{},"ISSN":["0254-8860","0975-0711"],"issn-type":[{"value":"0254-8860","type":"print"},{"value":"0975-0711","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"7 February 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 October 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 February 2023","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"PK, DH, AD, SS, and AR declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study was performed conforming to the Helsinki Declaration of 1975, as revised in 2000 and 2008 concerning human and animal rights, and the authors followed the policy concerning informed consent as shown on .","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics statement"}},{"value":"The authors are solely responsible for the data and the contents of the paper. In no way is the Editor-in-Chief, Editorial Board members the Indian Society of Gastroenterology\u00a0or the printer\/publishers responsible for the results\/findings and content of this article.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Disclaimer"}}]}}