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This submitted paper is not being currently submitted to any other journal and the material has not been published elsewhere. It will not be published elsewhere while under consideration to be published in your journal.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"All procedures in this study were conducted in accordance with the * Research Ethics Committee of the Faculty of Medicine, Cairo University, code: MD-232\u20132020* approved protocols.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human ethics"}},{"value":"MAA, HMA, MSS, SO, NN, MMB and HEK declare no conflict of interest regarding this manuscript.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interest"}}]}}