{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T05:19:26Z","timestamp":1792732766970,"version":"4.5.0"},"reference-count":31,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"},{"start":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T00:00:00Z","timestamp":1747008000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Discov Onc"],"DOI":"10.1007\/s12672-025-02533-z","type":"journal-article","created":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T12:40:43Z","timestamp":1747053643000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Application of ultrasound-guided microwave ablation combined with polidocanol injection in benign cystic-solid thyroid nodules and recurrence analysis"],"prefix":"10.1007","volume":"16","author":[{"given":"Sichen","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dali","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2025,5,12]]},"reference":[{"issue":"9","key":"2533_CR1","doi-asserted-by":"publisher","first-page":"2869","DOI":"10.1210\/clinem\/dgaa322","volume":"105","author":"G Grani","year":"2020","unstructured":"Grani G, et al. Contemporary thyroid nodule evaluation and management. J Clin Endocrinol Metab. 2020;105(9):2869\u201383.","journal-title":"J Clin Endocrinol Metab"},{"issue":"7","key":"2533_CR2","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1016\/S2213-8587(22)00101-2","volume":"10","author":"EK Alexander","year":"2022","unstructured":"Alexander EK, Cibas ES. Diagnosis of thyroid nodules. Lancet Diabetes Endocrinol. 2022;10(7):533\u20139.","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"9","key":"2533_CR3","doi-asserted-by":"publisher","first-page":"914","DOI":"10.1001\/jama.2018.0898","volume":"319","author":"C Durante","year":"2018","unstructured":"Durante C, et al. The diagnosis and management of thyroid nodules: a review. JAMA. 2018;319(9):914\u201324.","journal-title":"JAMA"},{"issue":"1","key":"2533_CR4","doi-asserted-by":"publisher","first-page":"22270","DOI":"10.1038\/s41598-021-01593-9","volume":"11","author":"J Li","year":"2021","unstructured":"Li J, et al. Efficacy on radiofrequency ablation according to the types of benign thyroid nodules. Sci Rep. 2021;11(1):22270.","journal-title":"Sci Rep"},{"issue":"7","key":"2533_CR5","doi-asserted-by":"publisher","first-page":"846","DOI":"10.1530\/EC-19-0236","volume":"8","author":"H Dossing","year":"2019","unstructured":"Dossing H, Bennedbaek FN, Hegedus L. Long-term outcome following laser therapy of benign cystic-solid thyroid nodules. Endocr Connect. 2019;8(7):846\u201352.","journal-title":"Endocr Connect"},{"key":"2533_CR6","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1146\/annurev-med-042220-015032","volume":"73","author":"K Kobaly","year":"2022","unstructured":"Kobaly K, Kim CS, Mandel SJ. Contemporary management of thyroid nodules. Annu Rev Med. 2022;73:517\u201328.","journal-title":"Annu Rev Med"},{"issue":"7","key":"2533_CR7","doi-asserted-by":"publisher","first-page":"666","DOI":"10.1159\/000522544","volume":"101","author":"M Senitko","year":"2022","unstructured":"Senitko M, et al. Microwave ablation for malignant central airway obstruction: a pilot study. Respiration. 2022;101(7):666\u201374.","journal-title":"Respiration"},{"issue":"3","key":"2533_CR8","first-page":"122","volume":"5","author":"H Zhang","year":"2022","unstructured":"Zhang H, Yu S, Xu H. Ultrasound-guided microwave ablation for symptomatic adenomyosis: more areas of concern for more uniform and promising outcomes. J Interv Med. 2022;5(3):122\u20136.","journal-title":"J Interv Med"},{"issue":"1","key":"2533_CR9","doi-asserted-by":"publisher","first-page":"2244713","DOI":"10.1080\/02656736.2023.2244713","volume":"40","author":"X Gao","year":"2023","unstructured":"Gao X, et al. Efficacy and safety of ultrasound-guided radiofrequency, microwave and laser ablation for the treatment of T1N0M0 papillary thyroid carcinoma on a large scale: a systematic review and meta-analysis. Int J Hyperthermia. 2023;40(1):2244713.","journal-title":"Int J Hyperthermia"},{"key":"2533_CR10","doi-asserted-by":"publisher","DOI":"10.1530\/ETJ-22-0175","author":"E Crespo Vallejo","year":"2023","unstructured":"Crespo Vallejo E, et al. Multiple overlapping microwave ablation in benign thyroid nodule: a single-center 24-month study. Eur Thyroid J. 2023;12(1):e220175. https:\/\/doi.org\/10.1530\/ETJ-22-0175.","journal-title":"Eur Thyroid J"},{"issue":"6","key":"2533_CR11","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1016\/j.bj.2021.11.009","volume":"45","author":"JH Sun","year":"2022","unstructured":"Sun JH, et al. Evaluation of recurrence risk in patients with papillary thyroid cancer through tumor-node-metastasis staging: a single-center observational study in Taiwan. Biomed J. 2022;45(6):923\u201330.","journal-title":"Biomed J"},{"key":"2533_CR12","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12030564","author":"H Adwan","year":"2022","unstructured":"Adwan H, et al. Percutaneous thermal ablation therapy of hepatocellular carcinoma (HCC): microwave ablation (MWA) versus laser-induced thermotherapy (LITT). Diagnostics (Basel). 2023;12(3):564. https:\/\/doi.org\/10.3390\/diagnostics12030564.","journal-title":"Diagnostics (Basel)"},{"issue":"1","key":"2533_CR13","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/s12880-022-00752-2","volume":"22","author":"X Deng","year":"2022","unstructured":"Deng X, et al. Effectiveness and safety of ultrasound-guided percutaneous microwave ablation for hepatic alveolar echinococcosis. BMC Med Imaging. 2022;22(1):27.","journal-title":"BMC Med Imaging"},{"issue":"1","key":"2533_CR14","doi-asserted-by":"publisher","first-page":"2285705","DOI":"10.1080\/02656736.2023.2285705","volume":"41","author":"Q Cai","year":"2024","unstructured":"Cai Q, et al. Percutaneous microwave ablation versus sclerotherapy for large hepatic hemangioma: a multi-center cohort study. Int J Hyperthermia. 2024;41(1):2285705.","journal-title":"Int J Hyperthermia"},{"issue":"12","key":"2533_CR15","first-page":"CD001732","volume":"12","author":"R de Avila Oliveira","year":"2021","unstructured":"de Avila Oliveira R, et al. Injection sclerotherapy for varicose veins. Cochrane Database Syst Rev. 2021;12(12):CD001732.","journal-title":"Cochrane Database Syst Rev"},{"issue":"9","key":"2533_CR16","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1097\/DSS.0000000000003520","volume":"48","author":"QD Nguyen","year":"2022","unstructured":"Nguyen QD, et al. Polidocanol: a review of off-label dermatologic uses. Dermatol Surg. 2022;48(9):961\u20136.","journal-title":"Dermatol Surg"},{"issue":"4","key":"2533_CR17","doi-asserted-by":"publisher","first-page":"479","DOI":"10.3348\/kjr.2020.1205","volume":"23","author":"YJ Dong","year":"2022","unstructured":"Dong YJ, et al. Efficacy of lauromacrogol injection for ablation of benign predominantly cystic thyroid nodules and related factors: a prospective study. Korean J Radiol. 2022;23(4):479\u201387.","journal-title":"Korean J Radiol"},{"issue":"1","key":"2533_CR18","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1016\/j.crad.2014.09.008","volume":"70","author":"CH Suh","year":"2015","unstructured":"Suh CH, et al. Ethanol ablation of predominantly cystic thyroid nodules: evaluation of recurrence rate and factors related to recurrence. Clin Radiol. 2015;70(1):42\u20137.","journal-title":"Clin Radiol"},{"issue":"7","key":"2533_CR19","doi-asserted-by":"publisher","first-page":"540","DOI":"10.1016\/S2213-8587(22)00139-5","volume":"10","author":"EK Alexander","year":"2022","unstructured":"Alexander EK, Doherty GM, Barletta JA. Management of thyroid nodules. Lancet Diabetes Endocrinol. 2022;10(7):540\u20138.","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"11","key":"2533_CR20","doi-asserted-by":"publisher","first-page":"2636","DOI":"10.1016\/j.acra.2023.02.002","volume":"30","author":"L Wang","year":"2023","unstructured":"Wang L, et al. Image-guided thermal ablation as a promising approach to both nontoxic and toxic autonomously functioning thyroid nodules. Acad Radiol. 2023;30(11):2636\u201346.","journal-title":"Acad Radiol"},{"issue":"1","key":"2533_CR21","doi-asserted-by":"publisher","first-page":"785","DOI":"10.1186\/s12885-023-11301-7","volume":"23","author":"X Min","year":"2023","unstructured":"Min X, et al. Comparison of the effectiveness of lauromacrogol injection for ablation and microwave ablation in the treatment of predominantly cystic thyroid nodules: a multicentre study. BMC Cancer. 2023;23(1):785.","journal-title":"BMC Cancer"},{"issue":"12","key":"2533_CR22","doi-asserted-by":"crossref","first-page":"916","DOI":"10.1055\/a-2144-4132","volume":"102","author":"JP Richter","year":"2023","unstructured":"Richter JP, Richter CP, Groner D. Ultrasound-guided ablation techniques for thyroid lesions. Laryngorhinootologie. 2023;102(12):916\u201327.","journal-title":"Laryngorhinootologie"},{"key":"2533_CR23","unstructured":"Beneat A, Oropallo A. Sclerotherapy. In StatPearls. 2024: Treasure Island (FL) ineligible companies. Disclosure: Alisha Oropallo declares no relevant financial relationships with ineligible companies."},{"issue":"5","key":"2533_CR24","doi-asserted-by":"publisher","first-page":"615","DOI":"10.2169\/internalmedicine.8034-21","volume":"61","author":"S Iio","year":"2022","unstructured":"Iio S, et al. Characteristics and treatment outcomes of small-bowel angioectasia in systemic sclerosis patients: a retrospective observational study. Intern Med. 2022;61(5):615\u201322.","journal-title":"Intern Med"},{"issue":"1","key":"2533_CR25","doi-asserted-by":"publisher","first-page":"e12","DOI":"10.1210\/clinem\/dgad357","volume":"109","author":"JE Noel","year":"2023","unstructured":"Noel JE, Sinclair CF. Radiofrequency ablation for benign thyroid nodules. J Clin Endocrinol Metab. 2023;109(1):e12\u20137.","journal-title":"J Clin Endocrinol Metab"},{"issue":"10","key":"2533_CR26","first-page":"605","volume":"103","author":"SA Wilson","year":"2021","unstructured":"Wilson SA, Stem LA, Bruehlman RD. Hypothyroidism: diagnosis and treatment. Am Fam Phys. 2021;103(10):605\u201313.","journal-title":"Am Fam Phys"},{"issue":"6","key":"2533_CR27","doi-asserted-by":"publisher","first-page":"3851","DOI":"10.1007\/s00330-023-10282-2","volume":"34","author":"W Shi","year":"2024","unstructured":"Shi W, et al. Safety and efficacy of microwave ablation for symptomatic benign thyroid nodules in children. Eur Radiol. 2024;34(6):3851\u201360.","journal-title":"Eur Radiol"},{"key":"2533_CR28","doi-asserted-by":"publisher","first-page":"622996","DOI":"10.3389\/fendo.2021.622996","volume":"12","author":"H Monpeyssen","year":"2021","unstructured":"Monpeyssen H, Alamri A, Ben Hamou A. Long-term results of ultrasound-guided radiofrequency ablation of benign thyroid nodules: state of the art and future perspectives-a systematic review. Front Endocrinol. 2021;12:622996.","journal-title":"Front Endocrinol"},{"issue":"4","key":"2533_CR29","doi-asserted-by":"publisher","first-page":"104259","DOI":"10.1016\/j.amjoto.2024.104259","volume":"45","author":"R Huang","year":"2024","unstructured":"Huang R, et al. Effect of different retention doses of ultrasound-guided polidocanol chemical ablation for benign cystic-solid thyroid nodules. Am J Otolaryngol. 2024;45(4):104259.","journal-title":"Am J Otolaryngol"},{"issue":"1","key":"2533_CR30","doi-asserted-by":"publisher","first-page":"210","DOI":"10.1016\/j.jvsv.2022.08.004","volume":"11","author":"J Cao","year":"2023","unstructured":"Cao J, et al. A systematic review and network meta-analysis of the effectiveness of sclerotherapy for venous malformation. J Vasc Surg Venous Lymphat Disord. 2023;11(1):210\u20138.","journal-title":"J Vasc Surg Venous Lymphat Disord"},{"issue":"2","key":"2533_CR31","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1002\/jcu.23134","volume":"50","author":"M Zhang","year":"2022","unstructured":"Zhang M, et al. Evaluation of efficacy of ultrasound-guided microwave ablation in primary hyperparathyroidism. J Clin Ultrasound. 2022;50(2):227\u201335.","journal-title":"J Clin Ultrasound"}],"container-title":["Discover Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12672-025-02533-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12672-025-02533-z\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12672-025-02533-z.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,12]],"date-time":"2025-05-12T12:40:45Z","timestamp":1747053645000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12672-025-02533-z"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,12]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,12]]}},"alternative-id":["2533"],"URL":"https:\/\/doi.org\/10.1007\/s12672-025-02533-z","relation":{},"ISSN":["2730-6011"],"issn-type":[{"value":"2730-6011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,12]]},"assertion":[{"value":"3 January 2025","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"29 April 2025","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"12 May 2025","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study was approved by the ethics committee of The First Hospital of Changsha and informed consent was obtained from all participating patients. This study complied with the Declaration of Helsinki.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"736"}}