{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T06:10:59Z","timestamp":1779257459630,"version":"3.51.4"},"reference-count":8,"publisher":"Springer Science and Business Media LLC","issue":"1","license":[{"start":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T00:00:00Z","timestamp":1778112000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Discov Onc"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The ureteral stump carcinoma after radical nephrectomy is exceedingly rare. We report a 75-year-old woman who underwent right laparoscopic nephrectomy in April 2024 for a renal mass detected during hypertension evaluation. Pathology confirmed clear cell RCC, ISUP grade 2, with negative ureteral margins. In December 2025, during cystoscopy for contralateral renal calculus management, A long pedunculated tumor, arising from the ureteral stump and protruding into the bladder, was incidentally discovered at the right ureteral orifice. Biopsy revealed low-grade non\u2011invasive TCC. Subsequent laparoscopic partial cystectomy and ureterectomy confirmed ureteral non\u2011invasive low\u2011grade TCC originating from the stump. This case highlights that even with initial negative margins, metachronous primary tumors may arise in the urinary tract, necessitating reconsideration of ureteral stump management after nephrectomy.<\/jats:p>","DOI":"10.1007\/s12672-026-05028-7","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T14:07:26Z","timestamp":1778162846000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Long pedunculated tumor from the ureteral stump protruding into the bladder after nephrectomy: a case report"],"prefix":"10.1007","volume":"17","author":[{"given":"Jiahao","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jintao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianbiao","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2026,5,7]]},"reference":[{"key":"5028_CR1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12081940","author":"S-Y Pan","year":"2022","unstructured":"Pan S-Y, Huang C-P, Chen W-C Synchronous\/metachronous multiple primary malignancies: review of associated risk factors. Diagnostics (Basel). 2022. https:\/\/doi.org\/10.3390\/diagnostics12081940.","journal-title":"Diagnostics (Basel)"},{"key":"5028_CR2","doi-asserted-by":"publisher","first-page":"1576764","DOI":"10.3389\/fonc.2025.1576764","volume":"15","author":"B Huang","year":"2025","unstructured":"Huang B, Yin W, Al-Qaisi MA, et al. Multiple synchronous primary malignant neoplasms of renal, ureter and urinary bladder: a case report. Front Oncol. 2025;15:1576764. https:\/\/doi.org\/10.3389\/fonc.2025.1576764.","journal-title":"Front Oncol"},{"issue":"6","key":"5028_CR3","doi-asserted-by":"publisher","first-page":"e2021380","DOI":"10.23750\/abm.v92i6.11768","volume":"92","author":"A Symeonidis","year":"2022","unstructured":"Symeonidis A, Tsikopoulos I, Symeonidis EN, et al. More than meets the eye: A case of synchronous ipsilateral clear cell renal cell carcinoma and urothelial carcinoma of the pelvicalyceal system and literature review. Acta Biomed. 2022;92(6):e2021380. https:\/\/doi.org\/10.23750\/abm.v92i6.11768.","journal-title":"Acta Biomed"},{"issue":"3","key":"5028_CR4","doi-asserted-by":"publisher","first-page":"126","DOI":"10.1007\/s13691-019-00369-3","volume":"8","author":"T Masago","year":"2019","unstructured":"Masago T, Naka T, Yoshida H, Takahashi C. Primary tumor of the ureteral stump after a radical nephrectomy for renal cell carcinoma: case report and literature review. Int Cancer Conf J. 2019;8(3):126\u20139. https:\/\/doi.org\/10.1007\/s13691-019-00369-3.","journal-title":"Int Cancer Conf J"},{"issue":"9","key":"5028_CR5","doi-asserted-by":"publisher","first-page":"e29103","DOI":"10.7759\/cureus.29103","volume":"14","author":"KW Perry","year":"2022","unstructured":"Perry KW, Taylor Z, Piraino J, McMahon G. Primary ureteral stump carcinoma: rare presentation and management. Cureus. 2022;14(9):e29103. https:\/\/doi.org\/10.7759\/cureus.29103.","journal-title":"Cureus"},{"issue":"11","key":"5028_CR6","doi-asserted-by":"publisher","first-page":"5064","DOI":"10.1016\/j.asjsur.2023.06.084","volume":"46","author":"C Yu","year":"2023","unstructured":"Yu C, Li Z, Niu Y, Li Z. A case of accidental renal pelvis carcinoma during percutaneous nephrolithotipsy. Asian J Surg. 2023;46(11):5064. https:\/\/doi.org\/10.1016\/j.asjsur.2023.06.084.","journal-title":"Asian J Surg"},{"issue":"5","key":"5028_CR7","doi-asserted-by":"publisher","first-page":"720","DOI":"10.21037\/tau-21-1041","volume":"11","author":"JY Kim","year":"2022","unstructured":"Kim JY, Yu JH, Sung LH, Kim HJ, Cho DY. Ureteral fibroepithelial polyp protruding into the bladder which mimics a bladder tumour: a case report and literature review. Translational Androl Urol. 2022;11(5):720\u20136. https:\/\/doi.org\/10.21037\/tau-21-1041.","journal-title":"Translational Androl Urol"},{"issue":"1","key":"5028_CR8","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1186\/s13256-021-03070-3","volume":"15","author":"S Akan","year":"2021","unstructured":"Akan S, Ediz C. A rare association in a patient with non-muscle invasive bladder cancer: ureteral fibroepithelial polyp and ipsilateral renal cell carcinoma: a case report. J Med Case Rep. 2021;15(1):475. https:\/\/doi.org\/10.1186\/s13256-021-03070-3.","journal-title":"J Med Case Rep"}],"container-title":["Discover Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12672-026-05028-7","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12672-026-05028-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12672-026-05028-7.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T05:41:24Z","timestamp":1779255684000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12672-026-05028-7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,7]]},"references-count":8,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2026,12]]}},"alternative-id":["5028"],"URL":"https:\/\/doi.org\/10.1007\/s12672-026-05028-7","relation":{},"ISSN":["2730-6011"],"issn-type":[{"value":"2730-6011","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,7]]},"assertion":[{"value":"29 January 2026","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 April 2026","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 May 2026","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The study protocol was approved by The Ethics Committee of Jiangxi Cancer Hospital, in accordance with\n                      the measures for ethical review of life sciences and medical research involving human beings (2023)\n                      issued by China\u2019s National Health Commission. Informed consent to participate was obtained from the patient.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics approval and consent to participate"}},{"value":"Informed consent to publish was obtained from the patient.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for publication"}},{"value":"The authors declare no competing interests.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing interests"}}],"article-number":"748"}}