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It does not present new primary patient data requiring separate ethical review. All cohort studies, case reports, and clinical analyses referenced herein received institutional ethical approval from Al Neelain University and\/or Assafa College (Approval ID: DSR-ACEC NO 19-6-3 and equivalent clearances), with informed consent obtained per Declaration of Helsinki standards. All patient data in referenced publications were anonymised; no identifiable information is included in this manuscript.","order":1,"name":"Ethics","label":"Ethics approval and consent to participate","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Written informed consent for the publication of de-identified clinical and genetic data was obtained from all participants or their legal guardians in the referenced studies. No individual-level identifiable information is presented in this Short Communication.","order":2,"name":"Ethics","label":"Consent for publication","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":3,"name":"Ethics","label":"Competing interests","group":{"name":"EthicsHeading","label":"Declarations"}}],"article-number":"121"}}