{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T11:03:33Z","timestamp":1788260613486,"version":"build-2803163510"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","issue":"2","license":[{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"},{"start":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T00:00:00Z","timestamp":1626134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Cardiovasc Interv and Ther"],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The clinical outcomes of patients undergoing percutaneous coronary intervention (PCI) for left main coronary artery (LMCA) malperfusion caused by acute type A aortic dissection (AAAD) remains largely unexplored. The aim of this study was to determine the clinical outcomes of patients undergoing PCI for LMCA malperfusion caused by AAAD. We examined nine consecutive patients undergoing PCI for LMCA malperfusion caused by AAAD between 1995 and 2020. The mean age was 55.4\u2009\u00b1\u20097.7\u00a0years. Eight patients presented cardiogenic shock, and five patients cardiopulmonary arrest. Two patients were diagnosed with AAAD before coronary angiography using computed tomography and transthoracic echocardiography, respectively, and in the other seven patients after coronary angiography using other modalities. Four patients underwent PCI on intra-aortic balloon pumping support, and four patients on venoarterial extracorporeal membrane oxygenation (VA-ECMO) support, including one patient on both. PCI was successful in eight patients, with final thrombolysis in myocardial infarction grade 2 or 3. The four patients on VA-ECMO did not undergo aortic dissection repair due to poor recovery of cardiac function and died during the hospital stay, and the other five patients had successful PCI, underwent aortic dissection repair, and remained alive at 5\u00a0year follow-up. In conclusion, LMCA malperfusion caused by AAAD seemed to have clinical presentations and electrocardiogram changes similar to acute coronary syndrome. PCI and subsequent surgical aortic repair saved the lives of all AAAD patients with LMCA malperfusion who had not required VA-ECMO.<\/jats:p>","DOI":"10.1007\/s12928-021-00793-4","type":"journal-article","created":{"date-parts":[[2021,7,13]],"date-time":"2021-07-13T13:03:21Z","timestamp":1626181401000},"page":"333-342","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Percutaneous coronary intervention for left main coronary artery malperfusion in acute type A aortic dissection"],"prefix":"10.1007","volume":"37","author":[{"given":"Yuya","family":"Taguchi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunsuke","family":"Kubo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiro","family":"Ikuta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Osakada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makoto","family":"Takamatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kotaro","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanobu","family":"Ohya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenobu","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuya","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Murai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Tada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Fuku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsuyoshi","family":"Goto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuhiko","family":"Komiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazushige","family":"Kadota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2021,7,13]]},"reference":[{"issue":"3","key":"793_CR1","doi-asserted-by":"publisher","first-page":"552","DOI":"10.1067\/mtc.2001.112534","volume":"121","author":"E Neri","year":"2001","unstructured":"Neri E, Toscano T, Papalia U, Frati G, Massetti M, Capannini G, et al. Proximal aortic dissection with coronary malperfusion: presentation, management, and outcome. J Thorac Cardiovasc Surg. 2001;121(3):552\u201360.","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"5","key":"793_CR2","doi-asserted-by":"publisher","first-page":"1471","DOI":"10.1016\/S0003-4975(03)00899-3","volume":"76","author":"K Kawahito","year":"2003","unstructured":"Kawahito K, Adachi H, Murata S, Yamaguchi A, Ino T. Coronary malperfusion due to type A aortic dissection: mechanism and surgical management. Ann Thorac Surg. 2003;76(5):1471\u20136 (discussion 1476).","journal-title":"Ann Thorac Surg"},{"issue":"3","key":"793_CR3","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1093\/ejcts\/ezt060","volume":"44","author":"K Imoto","year":"2013","unstructured":"Imoto K, Uchida K, Karube N, Yasutsune T, Cho T, Kimura K, et al. Risk analysis and improvement of strategies in patients who have acute type A aortic dissection with coronary artery dissection. Eur J Cardiothorac Surg. 2013;44(3):419\u201324 (discussion 424\u20135).","journal-title":"Eur J Cardiothorac Surg"},{"issue":"11","key":"793_CR4","doi-asserted-by":"publisher","first-page":"621","DOI":"10.1007\/s11748-018-1014-y","volume":"66","author":"K Uchida","year":"2018","unstructured":"Uchida K, Karube N, Minami T, Cho T, Matsuki Y, Nemoto H, et al. Treatment of coronary malperfusion in type A acute aortic dissection. Gen Thorac Cardiovasc Surg. 2018;66(11):621\u20135.","journal-title":"Gen Thorac Cardiovasc Surg"},{"issue":"14","key":"793_CR5","doi-asserted-by":"publisher","first-page":"e27","DOI":"10.1016\/j.jacc.2010.02.015","volume":"55","author":"Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, et al. American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines; American Association for Thoracic Surgery; American College of Radiology; American Stroke Association; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Interventional Radiology; Society of Thoracic Surgeons; Society for Vascular Medicine","year":"2010","unstructured":"Hiratzka LF, Bakris GL, Beckman JA, Bersin RM, Carr VF, Casey DE Jr, et al. American College of Cardiology Foundation\/American Heart Association Task Force on Practice Guidelines; American Association for Thoracic Surgery; American College of Radiology; American Stroke Association; Society of Cardiovascular Anesthesiologists; Society for Cardiovascular Angiography and Interventions; Society of Interventional Radiology; Society of Thoracic Surgeons; Society for Vascular Medicine. ACCF\/AHA\/AATS\/ACR\/ASA\/SCA\/SCAI\/SIR\/STS\/SVM Guidelines for the diagnosis and management of patients with thoracic aortic disease. A report of the American college of cardiology foundation\/american heart association task force on practice guidelines, American association for thoracic surgery, American college of radiology, American stroke association, society of cardiovascular anesthesiologists, society for cardiovascular angiography and interventions, society of interventional radiology, society of thoracic surgeons,and society for vascular medicine. J Am Coll Cardiol. 2010;55(14):e27\u2013129. https:\/\/doi.org\/10.1016\/j.jacc.2010.02.015 (Erratum in: J Am Coll Cardiol. 2013 Sep 10;62(11):1039\u201340).","journal-title":"J Am Coll Cardiol"},{"issue":"41","key":"793_CR6","doi-asserted-by":"publisher","first-page":"2873","DOI":"10.1093\/eurheartj\/ehu281","volume":"35","author":"Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, et al. ESC Committee for Practice Guidelines","year":"2014","unstructured":"Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H, et al. ESC Committee for Practice Guidelines. ESC Guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The task force for the diagnosis and treatment of aortic diseases of the European society of cardiology (ESC). Eur Heart J. 2014;35(41):2873\u2013926.","journal-title":"Eur Heart J"},{"key":"793_CR7","doi-asserted-by":"publisher","first-page":"b1807","DOI":"10.1136\/bmj.b1807","volume":"338","author":"Rathore SS, Curtis JP, Chen J, Wang Y, Nallamothu BK, Epstein AJ, et al. National Cardiovascular Data Registry","year":"2009","unstructured":"Rathore SS, Curtis JP, Chen J, Wang Y, Nallamothu BK, Epstein AJ, et al. National Cardiovascular Data Registry. Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study. BMJ. 2009;338:b1807.","journal-title":"BMJ"},{"issue":"1","key":"793_CR8","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1002\/1522-726X(200009)51:1<74::AID-CCD17>3.0.CO;2-F","volume":"51","author":"M Barabas","year":"2000","unstructured":"Barabas M, Gosselin G, Cr\u00e9peau J, Petitclerc R, Cartier R, Th\u00e9roux P. Left main stenting-as a bridge to surgery-for acute type A aortic dissection and anterior myocardial infarction. Catheter Cardiovasc Interv. 2000;51(1):74\u20137.","journal-title":"Catheter Cardiovasc Interv"},{"issue":"2","key":"793_CR9","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1583\/03-1120R.1","volume":"12","author":"K Imoto","year":"2005","unstructured":"Imoto K, Uchida K, Suzuki S, Isoda S, Karube N, Kimura K. Stenting of a left main coronary artery dissection and stent-graft implantation for acute type A aortic dissection. J Endovasc Ther. 2005;12(2):258\u201361.","journal-title":"J Endovasc Ther"},{"issue":"5","key":"793_CR10","doi-asserted-by":"publisher","first-page":"356","DOI":"10.14740\/jocmr2039w","volume":"7","author":"M Ruisi","year":"2015","unstructured":"Ruisi M, Fallahi A, Lala M, Kanei Y. Aortic dissection presenting as acute subtotal left main coronary artery occlusion: a case approach and review of the literature. J Clin Med Res. 2015;7(5):356\u201360.","journal-title":"J Clin Med Res"},{"issue":"7","key":"793_CR11","doi-asserted-by":"publisher","first-page":"398","DOI":"10.1007\/s11748-014-0406-x","volume":"62","author":"T Shimamoto","year":"2014","unstructured":"Shimamoto T, Komiya T. Clinical dilemma in the surgical treatment of organ malperfusion caused by acute type A aortic dissection. Gen Thorac Cardiovasc Surg. 2014;62(7):398\u2013406.","journal-title":"Gen Thorac Cardiovasc Surg"},{"issue":"2","key":"793_CR12","doi-asserted-by":"publisher","first-page":"104","DOI":"10.4330\/wjc.v7.i2.104","volume":"7","author":"Y Hanaki","year":"2015","unstructured":"Hanaki Y, Yumoto K, I S, Aoki H, Fukuzawa T, Watanabe T, Kato K. Coronary stenting with cardiogenic shock due to acute ascending aortic dissection. World J Cardiol. 2015;7(2):104\u201310.","journal-title":"World J Cardiol"},{"issue":"6","key":"793_CR13","doi-asserted-by":"publisher","first-page":"852","DOI":"10.1016\/j.amjcard.2006.10.055","volume":"99","author":"MS Hansen","year":"2007","unstructured":"Hansen MS, Nogareda GJ, Hutchison SJ. Frequency of and inappropriate treatment of misdiagnosis of acute aortic dissection. Am J Cardiol. 2007;99(6):852\u20136.","journal-title":"Am J Cardiol"},{"issue":"1","key":"793_CR14","doi-asserted-by":"publisher","first-page":"e5","DOI":"10.1016\/j.jemermed.2011.05.100","volume":"44","author":"TS G\u00fcven\u00e7","year":"2013","unstructured":"G\u00fcven\u00e7 TS, Erer HB, \u00c7etin R, Hasdemir H, \u0130lhan E, T\u00fcrkkan C, et al. Acute aortic regurgitation with myocardial infarction: an important clue for aortic dissection. J Emerg Med. 2013;44(1):e5-8.","journal-title":"J Emerg Med"},{"issue":"2","key":"793_CR15","doi-asserted-by":"publisher","first-page":"89","DOI":"10.1007\/s12928-015-0352-2","volume":"31","author":"S Hashimoto","year":"2016","unstructured":"Hashimoto S, Shiraishi J, Nakamura T, Nishikawa M, Yanagiuchi T, Ito D, et al. Survivors of acute myocardial infarction at left main trunk undergoing primary percutaneous coronary intervention. Cardiovasc Interv Ther. 2016;31(2):89\u201395.","journal-title":"Cardiovasc Interv Ther"},{"issue":"1","key":"793_CR16","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1002\/ccd.10168","volume":"56","author":"R Neri","year":"2002","unstructured":"Neri R, Migliorini A, Moschi G, Valenti R, Dovellini EV, Antoniucci D. Percutaneous reperfusion of left main coronary disease complicated by acute myocardial infarction. Catheter Cardiovasc Interv. 2002;56(1):31\u20134.","journal-title":"Catheter Cardiovasc Interv"},{"issue":"11","key":"793_CR17","doi-asserted-by":"publisher","first-page":"1513","DOI":"10.1016\/S0002-9149(99)00139-3","volume":"83","author":"SP Marso","year":"1999","unstructured":"Marso SP, Steg G, Plokker T, Holmes D, Park SJ, Kosuga K, et al. Catheter-based reperfusion of unprotected left main stenosis during an acute myocardial infarction (the ULTIMA experience). Unprotected left main trunk intervention multi-center assessment. Am J Cardiol. 1999;83(11):1513\u20137.","journal-title":"Am J Cardiol"},{"issue":"9351","key":"793_CR18","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/S0140-6736(03)12113-7","volume":"361","author":"EC Keeley","year":"2003","unstructured":"Keeley EC, Boura JA, Grines CL. Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials. Lancet. 2003;361(9351):13\u201320.","journal-title":"Lancet"},{"issue":"23","key":"793_CR19","doi-asserted-by":"publisher","first-page":"2145","DOI":"10.1016\/j.jacc.2009.08.024","volume":"54","author":"M Francone","year":"2009","unstructured":"Francone M, Bucciarelli-Ducci C, Carbone I, Canali E, Scardala R, Calabrese FA, et al. Impact of primary coronary angioplasty delay on myocardial salvage, infarct size, and microvascular damage in patients with ST-segment elevation myocardial infarction: insight from cardiovascular magnetic resonance. J Am Coll Cardiol. 2009;54(23):2145\u201353.","journal-title":"J Am Coll Cardiol"}],"container-title":["Cardiovascular Intervention and Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12928-021-00793-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12928-021-00793-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12928-021-00793-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,3,16]],"date-time":"2022-03-16T10:50:37Z","timestamp":1647427837000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12928-021-00793-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,13]]},"references-count":19,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["793"],"URL":"https:\/\/doi.org\/10.1007\/s12928-021-00793-4","relation":{},"ISSN":["1868-4300","1868-4297"],"issn-type":[{"value":"1868-4300","type":"print"},{"value":"1868-4297","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,13]]},"assertion":[{"value":"15 February 2021","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 July 2021","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2021","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors have no conflicts of interest to disclose.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}}]}}