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Dr. Hara received honoraria for lectures and proctoring from Abbott Medical Japan LLC. Dr. Kozuma received honoraria for lectures from Boston Scientific Japan K.K., Abbott Medical Japan LLC, Medtronic Japan Co., Ltd., Otsuka, Takeda, Daiichi-Sankyo, Amgen, and Novartis Pharma. Received a scholarship fund from Abbott Medical. All other authors declare no relevant relationships related to the content of this manuscript. Dr. Saji received honoraria for lectures from Medtronic Japan, Boston Scientific Japan, Abbott Medical Japan, Edwards LifeSciences, Japan lifeline and Daiichi-Sankyo.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of interest"}},{"value":"The study protocol was approved by the Independent Central Ethics Committee of the Clinical Research Promotion Network in Japan.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethical approval"}},{"value":"This study was performed as a secondary data analysis of anonymous information from the Japanese Structural Heart Disease, so the requirement for informed consent was waived.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to participate"}},{"value":"Not applicable.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent to publish"}}]}}