{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:55:14Z","timestamp":1791932114376,"version":"4.3.4"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T00:00:00Z","timestamp":1654128000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Transl. Stroke Res."],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1007\/s12975-022-01041-4","type":"journal-article","created":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T07:08:55Z","timestamp":1654153735000},"page":"438-442","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Vagus Nerve Stimulation for Stroke Motor Recovery\u2014What Is Next?"],"prefix":"10.1007","volume":"14","author":[{"given":"Zafer","family":"Keser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wuwei","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2022,6,2]]},"reference":[{"issue":"1","key":"1041_CR1","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1161\/STROKEAHA.115.010477","volume":"47","author":"J Dawson","year":"2016","unstructured":"Dawson J, Pierce D, Dixit A, Kimberley TJ, Robertson M, Tarver B, et al. Safety, feasibility, and efficacy of vagus nerve stimulation paired with upper-limb rehabilitation after ischemic stroke. Stroke. 2016;47(1):143\u201350.","journal-title":"Stroke"},{"issue":"11","key":"1041_CR2","doi-asserted-by":"publisher","first-page":"2789","DOI":"10.1161\/STROKEAHA.118.022279","volume":"49","author":"TJ Kimberley","year":"2018","unstructured":"Kimberley TJ, Pierce D, Prudente CN, Francisco GE, Yozbatiran N, Smith P, et al. Vagus nerve stimulation paired with upper limb rehabilitation after chronic stroke. Stroke. 2018;49(11):2789\u201392.","journal-title":"Stroke"},{"issue":"10284","key":"1041_CR3","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1016\/S0140-6736(21)00475-X","volume":"397","author":"J Dawson","year":"2021","unstructured":"Dawson J, Liu CY, Francisco GE, Cramer SC, Wolf SL, Dixit A, et al. Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial. Lancet. 2021;397(10284):1545\u201353.","journal-title":"Lancet"},{"issue":"1","key":"1041_CR4","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/s12975-020-00829-6","volume":"12","author":"DT Pruitt","year":"2021","unstructured":"Pruitt DT, Danaphongse TT, Lutchman M, Patel N, Reddy P, Wang V, et al. Optimizing dosing of vagus nerve stimulation for stroke recovery. Transl Stroke Res. 2021;12(1):65\u201371.","journal-title":"Transl Stroke Res"},{"issue":"3","key":"1041_CR5","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1016\/j.brs.2015.01.408","volume":"8","author":"CT Engineer","year":"2015","unstructured":"Engineer CT, Engineer ND, Riley JR, Seale JD, Kilgard MP. Pairing speech sounds with vagus nerve stimulation drives stimulus-specific cortical plasticity. Brain Stimul. 2015;8(3):637\u201344.","journal-title":"Brain Stimul"},{"issue":"10","key":"1041_CR6","doi-asserted-by":"publisher","first-page":"3097","DOI":"10.1161\/STROKEAHA.114.006654","volume":"45","author":"SA Hays","year":"2014","unstructured":"Hays SA, Khodaparast N, Hulsey DR, Ruiz A, Sloan AM, Rennaker RL 2nd, et al. Vagus nerve stimulation during rehabilitative training improves functional recovery after intracerebral hemorrhage. Stroke. 2014;45(10):3097\u2013100.","journal-title":"Stroke"},{"key":"1041_CR7","doi-asserted-by":"publisher","first-page":"8841752","DOI":"10.1155\/2020\/8841752","volume":"2020","author":"D Wu","year":"2020","unstructured":"Wu D, Ma J, Zhang L, Wang S, Tan B, Jia G. Effect and safety of transcutaneous auricular vagus nerve stimulation on recovery of upper limb motor function in subacute ischemic stroke patients: a randomized pilot study. Neural Plast. 2020;2020:8841752.","journal-title":"Neural Plast"},{"key":"1041_CR8","doi-asserted-by":"publisher","first-page":"7876507","DOI":"10.1155\/2017\/7876507","volume":"2017","author":"F Capone","year":"2017","unstructured":"Capone F, Miccinilli S, Pellegrino G, Zollo L, Simonetti D, Bressi F, et al. Transcutaneous vagus nerve stimulation combined with robotic rehabilitation improves upper limb function after stroke. Neural Plast. 2017;2017:7876507.","journal-title":"Neural Plast"},{"key":"1041_CR9","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.767302","volume":"15","author":"JL Chang","year":"2021","unstructured":"Chang JL, Coggins AN, Saul M, Paget-Blanc A, Straka M, Wright J, et al. Transcutaneous auricular vagus nerve stimulation (tAVNS) delivered during upper limb interactive robotic training demonstrates novel antagonist control for reaching movements following stroke. Front Neurosci. 2021;15: 767302.","journal-title":"Front Neurosci"},{"key":"1041_CR10","doi-asserted-by":"publisher","unstructured":"Dromerick AW, Geed S, Barth J, Brady K, Giannetti ML, Mitchell A, Edwardson MA, Tan MT, Zhou Y, Newport EL, Edwards DF. Critical period after stroke study (CPASS): a phase II clinical trial testing an optimal time for motor recovery after stroke in humans. Proc Natl Acad Sci USA. 2021;118(39).\u00a0https:\/\/doi.org\/10.1073\/pnas.2026676118.","DOI":"10.1073\/pnas.2026676118"}],"container-title":["Translational Stroke Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12975-022-01041-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12975-022-01041-4\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12975-022-01041-4.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T01:13:14Z","timestamp":1687914794000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12975-022-01041-4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,2]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,8]]}},"alternative-id":["1041"],"URL":"https:\/\/doi.org\/10.1007\/s12975-022-01041-4","relation":{},"ISSN":["1868-4483","1868-601X"],"issn-type":[{"value":"1868-4483","type":"print"},{"value":"1868-601X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,2]]},"assertion":[{"value":"19 May 2022","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"24 May 2022","order":2,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"2 June 2022","order":3,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"Not applicable.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Ethics Approval and Consent to Participate"}},{"value":"Not applicable.","order":3,"name":"Ethics","group":{"name":"EthicsHeading","label":"Human and Animal Ethics"}},{"value":"Both authors have read and approved the manuscript submission.","order":4,"name":"Ethics","group":{"name":"EthicsHeading","label":"Consent for Publication"}},{"value":"Dr. Feng was a site principal investigator for the VNS-Rehab study.","order":5,"name":"Ethics","group":{"name":"EthicsHeading","label":"Competing Interests"}},{"value":"Z.K. is an assistant professor of neurology at Mayo Clinic and W.F. is a professor of neurology at Duke University School of Medicine. Both authors are board certified vascular neurologists.","order":6,"name":"Ethics","group":{"name":"EthicsHeading","label":"Authors\u2019 Information"}}]}}