{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T23:36:47Z","timestamp":1791934607848,"version":"4.3.4"},"reference-count":35,"publisher":"Springer Science and Business Media LLC","issue":"5","license":[{"start":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T00:00:00Z","timestamp":1689206400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"},{"start":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T00:00:00Z","timestamp":1689206400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springernature.com\/gp\/researchers\/text-and-data-mining"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":["Transl. Stroke Res."],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1007\/s12975-023-01176-y","type":"journal-article","created":{"date-parts":[[2023,7,13]],"date-time":"2023-07-13T21:01:36Z","timestamp":1689282096000},"page":"916-924","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Effect of INR on Outcomes of Endovascular Treatment for Acute Vertebrobasilar Artery Occlusion"],"prefix":"10.1007","volume":"15","author":[{"given":"Yingjie","family":"Xu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixin","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghui","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaomiao","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianjun","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongyi","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoqiang","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2023,7,13]]},"reference":[{"issue":"2","key":"1176_CR1","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1161\/STROKEAHA.118.022466","volume":"50","author":"T Boeckh-Behrens","year":"2019","unstructured":"Boeckh-Behrens T, Pree D, Lummel N, et al. Vertebral artery patency and thrombectomy in basilar artery occlusions. Stroke. 2019;50(2):389\u201395.","journal-title":"Stroke"},{"issue":"11","key":"1176_CR2","doi-asserted-by":"publisher","first-page":"1002","DOI":"10.1016\/S1474-4422(11)70229-0","volume":"10","author":"HP Mattle","year":"2011","unstructured":"Mattle HP, Arnold M, Lindsberg PJ, et al. Basilar artery occlusion. Lancet Neurol. 2011;10(11):1002\u201314.","journal-title":"Lancet Neurol"},{"issue":"10","key":"1176_CR3","doi-asserted-by":"publisher","first-page":"1216","DOI":"10.1161\/01.STR.19.10.1216","volume":"19","author":"W Hacke","year":"1988","unstructured":"Hacke W, Zeumer H, Ferbert A, et al. Intra-arterial thrombolytic therapy improves outcome in patients with acute vertebrobasilar occlusive disease. Stroke. 1988;19(10):1216\u201322.","journal-title":"Stroke"},{"issue":"15","key":"1176_CR4","doi-asserted-by":"publisher","first-page":"1361","DOI":"10.1056\/NEJMoa2206317","volume":"387","author":"C Tao","year":"2022","unstructured":"Tao C, Nogueira RG, Zhu Y, et al. Trial of endovascular treatment of acute basilar-artery occlusion. N Engl J Med. 2022;387(15):1361\u201372.","journal-title":"N Engl J Med"},{"issue":"15","key":"1176_CR5","doi-asserted-by":"publisher","first-page":"1373","DOI":"10.1056\/NEJMoa2207576","volume":"387","author":"TG Jovin","year":"2022","unstructured":"Jovin TG, Li C, Wu L, et al. Trial of thrombectomy 6 to 24 hours after stroke due to basilar-artery occlusion. N Engl J Med. 2022;387(15):1373\u201384.","journal-title":"N Engl J Med"},{"issue":"5","key":"1176_CR6","doi-asserted-by":"publisher","first-page":"1687","DOI":"10.1161\/STROKEAHA.108.527804","volume":"40","author":"GJ del Zoppo","year":"2009","unstructured":"del Zoppo GJ, Levy DE, Wasiewski WW, et al. Hyperfibrinogenemia and functional outcome from acute ischemic stroke. Stroke. 2009;40(5):1687\u201391.","journal-title":"Stroke"},{"issue":"1\u20132","key":"1176_CR7","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.jns.2006.01.020","volume":"246","author":"W Turaj","year":"2006","unstructured":"Turaj W, S\u0142owik A, Dziedzic T, et al. Increased plasma fibrinogen predicts one-year mortality in patients with acute ischemic stroke. J Neurol Sci. 2006;246(1\u20132):13\u20139.","journal-title":"J Neurol Sci"},{"issue":"2","key":"1176_CR8","doi-asserted-by":"publisher","first-page":"e0211458","DOI":"10.1371\/journal.pone.0211458","volume":"14","author":"J Zhang","year":"2019","unstructured":"Zhang J, Liu L, Tao J, et al. Prognostic role of early D-dimer level in patients with acute ischemic stroke. PLoS\u00a0One. 2019;14(2):e0211458.","journal-title":"PLoS ONE"},{"issue":"3","key":"1176_CR9","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1159\/000196823","volume":"27","author":"P Welsh","year":"2009","unstructured":"Welsh P, Barber M, Langhorne P, et al. Associations of inflammatory and haemostatic biomarkers with poor outcome in acute ischaemic stroke. Cerebrovasc Dis. 2009;27(3):247\u201353.","journal-title":"Cerebrovasc Dis"},{"key":"1176_CR10","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1007\/978-1-62703-339-8_9","volume":"992","author":"V Ignjatovic","year":"2013","unstructured":"Ignjatovic V. Prothrombin time\/international normalized ratio. Methods Mol Biol. 2013;992:121\u20139.","journal-title":"Methods Mol Biol"},{"issue":"3","key":"1176_CR11","doi-asserted-by":"publisher","first-page":"192","DOI":"10.5847\/wjem.j.issn.1920-8642.2014.03.006","volume":"5","author":"A Verma","year":"2014","unstructured":"Verma A, Kole T. International normalized ratio as a predictor of mortality in trauma patients in India. World J Emerg Med. 2014;5(3):192\u20135.","journal-title":"World J Emerg Med"},{"issue":"4","key":"1176_CR12","doi-asserted-by":"publisher","first-page":"913","DOI":"10.1253\/circj.CJ-15-1326","volume":"80","author":"A Okada","year":"2016","unstructured":"Okada A, Sugano Y, Nagai T, et al. Prognostic value of prothrombin time international normalized ratio in acute decompensated heart failure \u2013 a combined marker of hepatic insufficiency and hemostatic abnormality. Circ J. 2016;80(4):913\u201323.","journal-title":"Circ J"},{"key":"1176_CR13","doi-asserted-by":"crossref","unstructured":"K\u0131r\u0131\u015f T, Yaz\u0131c\u0131 S, Durmu\u015f G, et al. The relation between international normalized ratio and mortality in acute pulmonary embolism: A retrospective study. J Clin Lab Anal. 2018;32(1):e22164.","DOI":"10.1002\/jcla.22164"},{"issue":"4","key":"1176_CR14","doi-asserted-by":"publisher","first-page":"378","DOI":"10.5551\/jat.43752","volume":"26","author":"X Xie","year":"2019","unstructured":"Xie X, Wang X, Li Z, et al. Prognostic value of international normalized ratio in ischemic stroke patients without atrial fibrillation or anticoagulation therapy. J Atheroscler Thromb. 2019;26(4):378\u201387.","journal-title":"J Atheroscler Thromb"},{"key":"1176_CR15","doi-asserted-by":"crossref","unstructured":"You S, Han Q, Dong X, et al. Prognostic significance of international normalised ratio and prothrombin time in Chinese acute ischaemic stroke patients. Postgrad Med J. 2023;99(1170):333\u201339.","DOI":"10.1136\/postgradmedj-2021-141204"},{"key":"1176_CR16","unstructured":"Chen H, Ahmad G, Colasurdo M, et al. Mildly elevated INR is associated with worse outcomes following mechanical thrombectomy for acute ischemic stroke. J Neurointerv Surg. 2022;jnis-2022-019283."},{"issue":"12","key":"1176_CR17","doi-asserted-by":"publisher","first-page":"3239","DOI":"10.1161\/STROKEAHA.117.018377","volume":"48","author":"JF Scheitz","year":"2017","unstructured":"Scheitz JF, Turc G, Kujala L, et al. Intracerebral hemorrhage and outcome after thrombolysis in stroke patients using selective serotonin-reuptake inhibitors. Stroke. 2017;48(12):3239\u201344.","journal-title":"Stroke"},{"issue":"4","key":"1176_CR18","doi-asserted-by":"publisher","first-page":"1116","DOI":"10.1161\/STROKEAHA.110.604652","volume":"42","author":"W Pfeilschifter","year":"2011","unstructured":"Pfeilschifter W, Spitzer D, Czech-Zechmeister B, et al. Increased risk of hemorrhagic transformation in ischemic stroke occurring during warfarin anticoagulation: an experimental study in mice. Stroke. 2011;42(4):1116\u201321.","journal-title":"Stroke"},{"issue":"2","key":"1176_CR19","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1212\/WNL.46.2.341","volume":"46","author":"D Toni","year":"1996","unstructured":"Toni D, Fiorelli M, Bastianello S, et al. Hemorrhagic transformation of brain infarct: predictability in the first 5 hours from stroke onset and influence on clinical outcome. Neurology. 1996;46(2):341\u20135.","journal-title":"Neurology"},{"issue":"12","key":"1176_CR20","doi-asserted-by":"publisher","first-page":"1432","DOI":"10.1111\/ene.13747","volume":"25","author":"G Zhang","year":"2018","unstructured":"Zhang G, He M, Xu Y, et al. Hemoglobin A1c predicts hemorrhagic transformation and poor outcomes after acute anterior stroke. Eur J Neurol. 2018;25(12):1432-e122.","journal-title":"Eur J Neurol"},{"issue":"10029","key":"1176_CR21","doi-asserted-by":"publisher","first-page":"1723","DOI":"10.1016\/S0140-6736(16)00163-X","volume":"387","author":"M Goyal","year":"2016","unstructured":"Goyal M, Menon BK, van Zwam WH, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723\u201331.","journal-title":"Lancet"},{"issue":"20","key":"1176_CR22","doi-asserted-by":"publisher","first-page":"1910","DOI":"10.1056\/NEJMoa2030297","volume":"384","author":"LCM Langezaal","year":"2021","unstructured":"Langezaal LCM, van der Hoeven EJRJ, Mont\u2019Alverne FJA, et al. Endovascular therapy for stroke due to basilar-artery occlusion. N Engl J Med. 2021;384(20):1910\u201320.","journal-title":"N Engl J Med"},{"issue":"2","key":"1176_CR23","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S1474-4422(19)30395-3","volume":"19","author":"X Liu","year":"2020","unstructured":"Liu X, Dai Q, Ye R, et al. Endovascular treatment versus standard medical treatment for vertebrobasilar artery occlusion (BEST): an open-label, randomised controlled trial. Lancet Neurol. 2020;19(2):115\u201322.","journal-title":"Lancet Neurol"},{"issue":"1","key":"1176_CR24","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1161\/01.STR.24.1.35","volume":"24","author":"HP Adams","year":"1993","unstructured":"Adams HP, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24(1):35\u201341.","journal-title":"Stroke."},{"issue":"9","key":"1176_CR25","doi-asserted-by":"publisher","first-page":"2485","DOI":"10.1161\/STROKEAHA.107.511162","volume":"39","author":"V Puetz","year":"2008","unstructured":"Puetz V, Sylaja PN, Coutts SB, et al. Extent of hypoattenuation on CT angiography source images predicts functional outcome in patients with basilar artery occlusion. Stroke. 2008;39(9):2485\u201390.","journal-title":"Stroke"},{"issue":"3","key":"1176_CR26","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1002\/ana.24336","volume":"77","author":"OC Singer","year":"2015","unstructured":"Singer OC, Berkefeld J, Nolte CH, et al. Mechanical recanalization in basilar artery occlusion: the ENDOSTROKE study. Ann Neurol. 2015;77(3):415\u201324.","journal-title":"Ann Neurol"},{"issue":"9","key":"1176_CR27","doi-asserted-by":"publisher","first-page":"2650","DOI":"10.1161\/STROKEAHA.113.001972","volume":"44","author":"OO Zaidat","year":"2013","unstructured":"Zaidat OO, Yoo AJ, Khatri P, et al. Recommendations on angiographic revascularization grading standards for acute ischemic stroke: a consensus statement. Stroke. 2013;44(9):2650\u201363.","journal-title":"Stroke"},{"issue":"2","key":"1176_CR28","first-page":"260","volume":"90","author":"SD Fihn","year":"2003","unstructured":"Fihn SD, Gadisseur AAP, Pasterkamp E, et al. Comparison of control and stability of oral anticoagulant therapy using acenocoumarol versus phenprocoumon. Thromb Haemost. 2003;90(2):260\u20136.","journal-title":"Thromb Haemost"},{"issue":"11","key":"1176_CR29","doi-asserted-by":"publisher","first-page":"1077","DOI":"10.1136\/neurintsurg-2021-018003","volume":"14","author":"L Xiao","year":"2022","unstructured":"Xiao L, Gu M, Lu Y, et al. Influence of renal impairment on clinical outcomes after endovascular recanalization in vertebrobasilar artery occlusions. J Neurointerv Surg. 2022;14(11):1077\u201383.","journal-title":"J Neurointerv Surg"},{"issue":"10","key":"1176_CR30","doi-asserted-by":"publisher","first-page":"2981","DOI":"10.1161\/STROKEAHA.115.010049","volume":"46","author":"R von Kummer","year":"2015","unstructured":"von Kummer R, Broderick JP, Campbell BCV, et al. The Heidelberg bleeding classification: classification of bleeding events after ischemic stroke and reperfusion therapy. Stroke. 2015;46(10):2981\u20136.","journal-title":"Stroke"},{"issue":"5","key":"1176_CR31","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1001\/jamaneurol.2020.0156","volume":"77","author":"W Zi","year":"2020","unstructured":"Zi W, Qiu Z, Wu D, et al. Assessment of endovascular treatment for acute basilar artery occlusion via a nationwide prospective registry. JAMA Neurol. 2020;77(5):561\u201373.","journal-title":"JAMA Neurol"},{"issue":"2","key":"1176_CR32","doi-asserted-by":"publisher","first-page":"301","DOI":"10.1007\/s11239-015-1235-1","volume":"41","author":"H Tamim","year":"2016","unstructured":"Tamim H, Habbal M, Saliba A, et al. Preoperative INR and postoperative major bleeding and mortality: a retrospective cohort study. J Thromb Thrombolysis. 2016;41(2):301\u201311.","journal-title":"J Thromb Thrombolysis"},{"issue":"8","key":"1176_CR33","doi-asserted-by":"publisher","first-page":"3161","DOI":"10.1182\/blood-2006-09-003004","volume":"109","author":"LO Mosnier","year":"2007","unstructured":"Mosnier LO, Zlokovic BV, Griffin JH. The cytoprotective protein C pathway. Blood. 2007;109(8):3161\u201372.","journal-title":"Blood"},{"issue":"2","key":"1176_CR34","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1016\/j.atherosclerosis.2009.05.002","volume":"207","author":"U Sadat","year":"2009","unstructured":"Sadat U, Weerakkody RA, Bowden DJ, et al. Utility of high resolution MR imaging to assess carotid plaque morphology: a comparison of acute symptomatic, recently symptomatic and asymptomatic patients with carotid artery disease. Atherosclerosis. 2009;207(2):434\u20139.","journal-title":"Atherosclerosis"},{"issue":"8","key":"1176_CR35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0221112","volume":"14","author":"GE Delgado","year":"2019","unstructured":"Delgado GE, Zirlik A, Gruber R, et al. The association of high-normal international-normalized-ratio (INR) with mortality in patients referred for coronary angiography. PLoS\u00a0One. 2019;14(8): e0221112.","journal-title":"PLoS ONE"}],"container-title":["Translational Stroke Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12975-023-01176-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/article\/10.1007\/s12975-023-01176-y\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/s12975-023-01176-y.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T08:31:06Z","timestamp":1725006666000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/s12975-023-01176-y"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,13]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["1176"],"URL":"https:\/\/doi.org\/10.1007\/s12975-023-01176-y","relation":{},"ISSN":["1868-4483","1868-601X"],"issn-type":[{"value":"1868-4483","type":"print"},{"value":"1868-601X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,13]]},"assertion":[{"value":"29 June 2023","order":1,"name":"received","label":"Received","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"4 July 2023","order":2,"name":"revised","label":"Revised","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"7 July 2023","order":3,"name":"accepted","label":"Accepted","group":{"name":"ArticleHistory","label":"Article History"}},{"value":"13 July 2023","order":4,"name":"first_online","label":"First Online","group":{"name":"ArticleHistory","label":"Article History"}},{"order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Declarations"}},{"value":"The authors declare no competing interests.","order":2,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}