{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T18:11:29Z","timestamp":1791483089024,"version":"4.3.4"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","issue":"4","license":[{"start":{"date-parts":[[2010,6,8]],"date-time":"2010-06-08T00:00:00Z","timestamp":1275955200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Med. Toxicol."],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1007\/s13181-010-0092-8","type":"journal-article","created":{"date-parts":[[2010,6,7]],"date-time":"2010-06-07T19:50:38Z","timestamp":1275940238000},"page":"443-447","source":"Crossref","is-referenced-by-count":35,"title":["Complications of Oral Exposure to Fentanyl Transdermal Delivery System Patches"],"prefix":"10.1007","volume":"6","author":[{"given":"Jane M.","family":"Prosser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brent E.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewis","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2010,6,8]]},"reference":[{"key":"92_CR1","doi-asserted-by":"crossref","first-page":"422","DOI":"10.2165\/00003088-198308050-00004","volume":"8","author":"LE Mather","year":"1983","unstructured":"Mather LE (1983) Clinical pharmacokinetics of fentanyl and its newer derivatives. Clin Pharmacokinet 8:422\u2013446","journal-title":"Clin Pharmacokinet"},{"key":"92_CR2","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1001\/archinte.167.16.1752","volume":"167","author":"TJ Moore","year":"2007","unstructured":"Moore TJ, Cohen MR, Furberg CD (2007) Serious adverse drug events reported to the food and drug administration, 1998\u20132005. Arch Intern Med 167:1752\u20131758","journal-title":"Arch Intern Med"},{"key":"92_CR3","unstructured":"Nelson LS (2006) Opioids. In: Goldfrank\u2019s Toxicologic Emergencies. 8th (ed.) New York: McGraw-Hill, pp 540\u2013613"},{"key":"92_CR4","unstructured":"http:\/\/drugtopics.modernmedicine.com\/Pharmacy+Facts+&+Figures . Last accessed 03\/28\/08."},{"key":"92_CR5","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1007\/BF03178274","volume":"5","author":"LS Nelson","year":"2009","unstructured":"Nelson LS, Schwaner R (2009) Transdermal fentanyl: pharmacology and toxicology. J Med Toxicol 5:230\u2013241","journal-title":"J Med Toxicol"},{"key":"92_CR6","unstructured":"Janssen Pharmaceutical. Duragesic\u00aeapproved package insert. Titusville, NJ. Available from: http:\/\/www.duragesic.com\/duragesic\/shared\/pi\/duragesic.pdf . Last accessed 06\/06\/2009."},{"key":"92_CR7","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1093\/jat\/24.7.627","volume":"24","author":"DT Anderson","year":"2000","unstructured":"Anderson DT, Muto JJ (2000) Duragesic transdermal patch: postmortem tissue distribution of fentanyl in 25 cases. J Anal Toxicol 24:627\u2013634","journal-title":"J Anal Toxicol"},{"key":"92_CR8","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.annemergmed.2005.06.450","volume":"45","author":"TP Coon","year":"2005","unstructured":"Coon TP, Miller M, Kaylor D, Jones-Spangle K (2005) Rectal Insertion of fentanyl patches: a new route of toxicity. Ann Emerg Med 45:473","journal-title":"Ann Emerg Med"},{"key":"92_CR9","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1097\/01.paf.0000127398.67081.11","volume":"25","author":"AM Tharp","year":"2004","unstructured":"Tharp AM, Winecker RE, Winston DC (2004) Fatal intravenous fentanyl abuse: four cases involving extraction of fentanyl from transdermal patches. Am J Forensic Med Pathol 25:178\u2013181","journal-title":"Am J Forensic Med Pathol"},{"key":"92_CR10","first-page":"75","volume":"32","author":"KA Marquardt","year":"1994","unstructured":"Marquardt KA, Tharratt RS (1994) Inhalation abuse of fentanyl patch. Clin Toxicol 32:75\u201378","journal-title":"Clin Toxicol"},{"key":"92_CR11","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00000542-199108000-00009","volume":"75","author":"JB Streisand","year":"1991","unstructured":"Streisand JB, Varvel JR, Stanski DR et al (1991) Absorption and bioavailability of oral transmucosal fentanyl citrate. Anesthesiology 75:223\u2013229","journal-title":"Anesthesiology"},{"key":"92_CR12","unstructured":"Jentzen JM. Alternative drug-delivery systems are subject to abuse. In: Clinical and Forensic Toxicology News. http:\/\/www.aacc.org\/publications\/toxicology\/Documents\/9023f590e32540b29c02cf27a1320efedec03.pdf . Last accessed 09\/01\/2009."},{"key":"92_CR13","first-page":"30","volume":"46","author":"F Barrueto Jr","year":"2004","unstructured":"Barrueto F Jr, Howland MA, Hoffman RS (2004) The fentanyl tea bag. Vet Human Toxicol 46:30\u201331","journal-title":"Vet Human Toxicol"},{"key":"92_CR14","unstructured":"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/InformationbyDrugClass\/ucm163647.htm . Last accessed 10\/20\/2009."},{"key":"92_CR15","unstructured":"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm172039.htm . Last accessed 10\/20\/2009."},{"key":"92_CR16","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1097\/00000542-198906000-00008","volume":"70","author":"JR Varvel","year":"1989","unstructured":"Varvel JR, Shafer SL, Hwang SS et al (1989) Absorbtion characteristics of transdermally administered fentanyl. Anesthesiology 70:928\u2013934","journal-title":"Anesthesiology"},{"key":"92_CR17","first-page":"706","volume":"47","author":"AM Arroyo","year":"2009","unstructured":"Arroyo AM, Smith J, Kriger S, Mowry J (2009) In-vitro release of fentanyl from transdermal patches in gastric and intestinal fluid. Clin Toxicol 47:706","journal-title":"Clin Toxicol"},{"key":"92_CR18","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1097\/00007611-199709000-00023","volume":"90","author":"WE Hardwick","year":"1997","unstructured":"Hardwick WE, King WD, Palmisano PA (1997) Respiratory depression in a child unintentionally exposed to transdermal fentanyl patch. South Med J 90:962\u2013964","journal-title":"South Med J"},{"key":"92_CR19","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1177\/106002809502901001","volume":"29","author":"KA Marquardt","year":"1995","unstructured":"Marquardt KA, Tharratt RS, Musallam NA (1995) Fentanyl remaining in a transdermal system following three days of continuous use. Ann Pharmacother 29:969\u2013971","journal-title":"Ann Pharmacother"},{"key":"92_CR20","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/j.1556-4029.2007.00597.x","volume":"53","author":"KL Woodall","year":"2008","unstructured":"Woodall KL, Martin TL, McLellan BA (2008) Oral abuse of fentanyl patches (Duragesic): seven case reports. J Forensic Sci 53:222\u2013225","journal-title":"J Forensic Sci"},{"key":"92_CR21","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/jat\/27.7.499","volume":"27","author":"JJ Kuhlman","year":"2003","unstructured":"Kuhlman JJ, McCaulley R, Valouch TJ, Behonick GS (2003) Fentanyl use, misuse, and abuse: a summary of 23 postmortem cases. J Anal Toxicol 27:499\u2013504","journal-title":"J Anal Toxicol"},{"key":"92_CR22","first-page":"385","volume":"98","author":"C Kramer","year":"1998","unstructured":"Kramer C, Tawney M (1998) A fatal overdose of transdermally administered fentanyl. J Am Osteo Assoc 98:385","journal-title":"J Am Osteo Assoc"},{"key":"92_CR23","doi-asserted-by":"crossref","first-page":"59","DOI":"10.2165\/00003088-200038010-00004","volume":"38","author":"S Grond","year":"2000","unstructured":"Grond S, Radbruch L, Lehmann KA (2000) Clinical pharmacokinetics of transdermal opioids: focus on transdermal fentanyl. Clin Pharmacokinet 38:59\u201389","journal-title":"Clin Pharmacokinet"},{"key":"92_CR24","unstructured":"Howland MA (2006) Antidotes in depth: naloxone. In Goldfrank\u2019s Toxicologic Emergencies 8th (ed.) New York: McGraw-Hill. pp 540\u2013613"}],"container-title":["Journal of Medical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-010-0092-8.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/article\/10.1007\/s13181-010-0092-8\/fulltext.html","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/s13181-010-0092-8","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T17:23:10Z","timestamp":1559582590000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/s13181-010-0092-8"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6,8]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["92"],"URL":"https:\/\/doi.org\/10.1007\/s13181-010-0092-8","relation":{},"ISSN":["1556-9039","1937-6995"],"issn-type":[{"value":"1556-9039","type":"print"},{"value":"1937-6995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,6,8]]}}}